Reference : Diamine oxidase in Serum and Small Intestinal Biopsy Tissue in Childhood Celiac Disease
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
Diamine oxidase in Serum and Small Intestinal Biopsy Tissue in Childhood Celiac Disease
FORGET, Patricia [Centre Hospitalier Universitaire de Liège - CHU > > Pédiatrie CHR >]
Grandfils, Christian mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine >]
Van Cutsem, J. L. [Liège University > Department of Pediatrics > > >]
Dandrifosse, Guy mailto [Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine) >]
Journal of Pediatric Gastroenterology and Nutrition
Lippincott Williams & Wilkins
Yes (verified by ORBi)
[en] Diamine oxidase ; Celiac disease ; Serum diamine oxidase activity
[en] A relationship between disaccharidase and diamine oxidase (DAO) activities was looked for by measuring these enzyme activities in histologically normal small intestinal biopsies of 18 children. The range for disaccharidase activities expressed in U g-1 wet weight was 0.1-5.7, 7.1-36.7, and 2.3-8.5 for lactase, maltase, and sucrase, respectively. The range for DAO activities expressed in nmol h-1 g-1 wet weight was 202-974. Significant correlations were found between disaccharidase and DAO activities (lactase versus DAO: n = 17, r = 0.80, P < 0.001; maltase versus DAO: n = 18, r = 0.70, P < 0.001; sucrase versus DAO: n = 18, r = 0.55, P < 0.05). Our results further support the hypothesis that DAO is a marker of small intestinal functional integrity in children.
Departments of Pediatrics and General and Comparative Biochemistry

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1986 Forget n°14.PDFPublisher postprint3.95 MBRequest copy

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