[en] Owing to their shape, accurately calibrated microspheres appear to be very suitable material for distal embolization. Moreover, the biocompatible (D,L) polylactide (PLA) microspheres possess two other valuable advantages: easy adjustment of their biodegradation rate, and incorporation of chemotherapeutic agents during their production. The authors describe the preparation of these (D,L) PLA microspheres and their clinical applications as a preliminary step to arterial chemoembolization.
Research Center/Unit :
Department of Neuroradiology and Department of Macromolecular Chemistry and Organic Catalysis
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Grandfils, Christian ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine
Flandroy, Pierre; Université de Liège - ULiège > Neuroradiologie
Nihant, Nicole; Université de Liège - ULiège > Neuroradiologie
Barbette, S; Université de Liège - ULiège > Neuroradiologie
Jérôme, Robert ; Université de Liège - ULiège > Département de chimie (sciences) > Département de chimie (sciences)