Reference : Microencapsulation by Coacervation of Poly(lactide-co-glycolide)-II:Encapsulation of ...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/144609
Microencapsulation by Coacervation of Poly(lactide-co-glycolide)-II:Encapsulation of a Dispersed Aqueous Phase
English
Nihant, Nicole []
Stassen, S []
Grandfils, Christian mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine >]
Jérôme, Robert mailto [Université de Liège - ULiège > Département de chimie (sciences) > Département de chimie (sciences) >]
Teyssié, Ph []
1993
polymer International
32
171-176
Yes (verified by ORBi)
International
0959-8103
[en] Microencapsulation ; Coacervation ; Surface tension ; Interfacial ; Tension ; Polylactide ; Polylactide-co-glycolide ; Protein encapsulation
[en] This paper is related to the phase separation of different copolyesters of lactides and glycolide solutions induced by the addition of silicone oil in order to promote microencapsulation of proteins. This coating process can be divided in three successive steps: phase separation of the coating polymer; adsorption of the coacervate droplets around the drugs phase, and microcapsule solidification. This paper focuses on the physico-chemical analysis of the second step. The knowledge of the interfacial tensions between the three liquid phases allows understanding of the microscopic evolution of the phase separation medium.
Center for Education and Research on Macromolecules (CERM) - University of Liege
http://hdl.handle.net/2268/144609

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