Reference : Dermal ultrastructure in low Beighton score members of 17 families with hypermobile-t...
Scientific journals : Article
Human health sciences : Dermatology
http://hdl.handle.net/2268/137946
Dermal ultrastructure in low Beighton score members of 17 families with hypermobile-type Ehlers-Danlos syndrome.
English
Hermanns-Lê, Trinh mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
REGINSTER, Marie-Annick mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Franchimont, Claudine mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
Delvenne, Philippe mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques >]
PIERARD, Gérald mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Manicourt, Daniel [> >]
2012
Journal of Biomedicine and Biotechnology
2012
878107
Yes (verified by ORBi)
International
1110-7243
1110-7251
United States
[en] The distinction between the Ehlers-Danlos syndrome hypermobile type (EDSH) and the benign joint hypermobility syndrome (BJHS) is unclear. The aim of the present study was to compare skin ultrastructural abnormalities of EDSH and BJHS among different families. Skin of 23 EDSH, 27 BJHS, and 41 asymptomatic subjects from 17 families was examined using transmission electron microscopy. Similar ultrastructural abnormalities were found irrespective of the Beighton score. Flower-like collagen fibrils represented the key change and elastic fibers were altered as well. Beighton score is a clinical parameter rating joint mobility that appeared unrelated to quantitative and qualitative collagen ultrastructural alterations in the skin. Some EDSH family members fit with BJHS diagnosis. BJHS possibly represents a mild variant of EDSH.
http://hdl.handle.net/2268/137946
10.1155/2012/878107

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
DERMAL ULTRASTRUCTURE.pdfPublisher postprint1.02 MBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.