Article (Scientific journals)
Is there anybody in there? Detecting awareness in disorders of consciousness.
Demertzi, Athina; Vanhaudenhuyse, Audrey; Bruno, Marie-Aurelie et al.
2008In Expert Review of Neurotherapeutics, 8 (11), p. 1719-30
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Keywords :
Awareness/physiology; Brain/physiopathology; Consciousness Disorders/diagnosis; Diagnosis, Differential; Diagnostic Imaging/methods; Electrophysiology; Humans; Neurologic Examination
Abstract :
[en] The bedside detection of awareness in disorders of consciousness (DOC) caused by acquired brain injury is not an easy task. For this reason, differential diagnosis using neuroimaging and electrophysiological tools in search for objective markers of consciousness is being employed. However, such tools cannot be considered as diagnostic per se, but as assistants to the clinical evaluation, which, at present, remains the gold standard. Regarding therapeutic management in DOC, no evidence-based recommendations can be made in favor of a specific treatment. The present review summarizes clinical and paraclinical studies that have been conducted with neuroimaging and electrophysiological techniques in search of residual awareness in DOC. We discuss the medical, scientific and ethical implications that derive from these studies and we argue that, in the future, the role of neuroimaging and electrophysiology will be important not only for the diagnosis and prognosis of DOC but also in establishing communication with these challenging patients.
Disciplines :
Neurology
Author, co-author :
Demertzi, Athina  ;  Université de Liège - ULiège > Consciousness-Physiology of Cognition
Vanhaudenhuyse, Audrey  ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Bruno, Marie-Aurelie
Schnakers, Caroline ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Boly, Mélanie ;  Université de Liège - ULiège > Département des sciences cliniques > Neurologie
BOVEROUX, Pierre 
Maquet, Pierre  ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Moonen, Gustave  ;  Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Laureys, Steven  ;  Université de Liège - ULiège > Centre de recherches du cyclotron
Language :
English
Title :
Is there anybody in there? Detecting awareness in disorders of consciousness.
Publication date :
2008
Journal title :
Expert Review of Neurotherapeutics
ISSN :
1473-7175
eISSN :
1744-8360
Publisher :
Taylor & Francis, United Kingdom
Volume :
8
Issue :
11
Pages :
1719-30
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 07 January 2013

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