Processing aortic and pulmonary artery waveforms to derive the ventricle time-varying elastance

Cardiovascular system; Intensive Care Unit; Model-based cardiac diagnosis; Porcine model; Pressure waveform; Signal Processing; Time-varying elastance

Abstract :

[en] Time-varying elastance of the ventricles is an important metric both clinically and as an input for a previously developed cardiovascular model. However, currently time-varying elastance is not normally available in an Intensive Care Unit (ICU) setting, as it is an invasive and ethically challenging metric to measure. A previous paper developed a method to map less invasive metrics to the driver function, enabling an estimate to be achieved without invasive measurements. This method requires reliable and accurate processing of the aortic and pulmonary artery pressure waveforms to locate the specific points that are required to estimate the driver function. This paper details the method by which these waveforms are processed, using a data set of five pigs induced with pulmonary embolism, and five pigs induced with septic shock (with haemofiltration), adding up to 88 waveforms (for each of aortic and pulmonary artery pressure), and 616 points in total to locate. 98.2% of all points were located to within 1% of their true value, 0.81% were between 1% and 5%, 0.65% were between 5% and 10%, the remaining 0.32% were below 20%.© 2011 IFAC.

Disciplines :

Engineering, computing & technology: Multidisciplinary, general & others

Author, co-author :

Stevenson, D. J.; Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand

Hann, C. E.; Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand

Chase, G. J.; Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand

Revie, J.; Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand

Shaw, G. M.; Department of Intensive Care, Christchurch Hospital, Christchurch, New Zealand

Desaive, Thomas ; Université de Liège - ULiège > Département d'astrophys., géophysique et océanographie (AGO) > Thermodynamique des phénomènes irréversibles

LAMBERMONT, Bernard ; Centre Hospitalier Universitaire de Liège - CHU > Frais communs médecine

GHUYSEN, Alexandre ; Centre Hospitalier Universitaire de Liège - CHU > Urgences

Kolh, Philippe ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, humaines et path.

Heldmann, S.; Department of Mechanical Engineering, TU Darmstadt, Germany

Language :

English

Title :

Processing aortic and pulmonary artery waveforms to derive the ventricle time-varying elastance

Publication date :

2011

Event name :

18th IFAC World Congress

Event date :

28 August 2011 through 2 September 2011

Audience :

International

Journal title :

IFAC Proceedings Volumes

ISSN :

1474-6670

eISSN :

2589-3653

Publisher :

Elsevier

Volume :

Issue :

PART 1

Pages :

587-592

Peer reviewed :

Peer Reviewed verified by ORBi

Commentary :

86642 9783902661937

Available on ORBi :

since 12 October 2012

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