Gestion de la glycémie aux soins intensifs

[en] The aim of this article is to describe the current status and understanding and the clinical data related to the effects of Tight Glucose Control by Intensive Insulin therapy, TGCIIT, in critically ill patients. Recent prospectively collected data, from one centre, demonstrated decreases of mortality and of various other outcomes in critically ill patients treated with TGCIIT. These results are currently awaiting confirmation, although available data from prospective multi-centre studies do not seem to support the external validity of the beneficial effects of TGCIIT titrated to restore blood glucose between 80 and 110 mg/dl. Also, recent data raised new closely related and relevant issues including the variability of blood glucose, the risks of hypoglycaemia, and the delineation of the categories of patients in whom TGCIIT could bring an actual benefit.

Disciplines :

Anesthesia & intensive care

Author, co-author :

Preiser, Jean-Charles ; Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)

Devos, P.

Language :

French

Title :

Gestion de la glycémie aux soins intensifs

Alternative titles :

[en] Management of Blood Glucose Level in Intensive Care

Publication date :

2007

Journal title :

Revue Médicale de Liège

ISSN :

0370-629X

eISSN :

2566-1566

Publisher :

Université de Liège. Revue Médicale de Liège, Liège, Belgium

Volume :

62 Spec No

Pages :

51-4

Available on ORBi :

since 19 September 2012

Statistics

Number of views

72 (3 by ULiège)

Number of downloads

0 (0 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenAlex citations

Bibliography

Van den Berghe G, Wouters P, Weekers F, et al. - Intensive insulin therapy in the critically ill patients. N Engl J Med, 2001, 345, 1359-1367.
Van den Berghe G, Wilmer A, Hermans G, et al. - Intensive insulin therapy in the medical ICU. N Engl J Med, 2006, 354, 449-461.
Van den Berghe G, Wilmer A, Milants I, et al.- Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes, 2006, 55, 31513159.
Van den Berghe G, Wouters PJ, Kesteloot K, et al. - Analysis of healthcare resource utilization with intensive insulin therapy in critically ill patients. Crit Care Med, 2006, 34, 612-616.
Brownlee M. - Biochemistry and molecular cell biology of diabetic complications. Nature, 2001, 414, 813-820.
Hirsch IB, Brownlee M. - Should minimal blood glucose variability become the gold standard of glycemic control?. J Diabetes Complications, 2005, 19, 178-181.
Garcia Soriano F, Virag L, Jagtap P, et al. - Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med, 2001, 7, 108-113.
Szabo C, Biser A, Benko R, et al. - Poly(ADP-Ribose) polymerase inhibitors ameliorate nephropathy of type 2 diabetic Leprdb/db Mice. Diabetes, 2006, 55, 3004-3012.
Ceriello A. - Oxidative stress and diabetes-associated complications. Endocr Pract, 2006, 12, 60-62.
Corstjens AM, van der Horst IC, Zijlstra JG, et al. - Hyperglycaemia in critically ill patients: marker or mediator of mortality? Crit Care, 2006, 10, 216.
Krinsley JS. - Effect of an intensive glucose management protocol on the mortality of critically ill adult patients. Mayo Clin Proc, 2004, 79, 992-1000.
Finney SJ, Zekveld C, Elia A, et al. - Glucose control and mortality in critically ill patients. JAMA, 2003, 290, 2041-2047.
Gabbanelli V, Pantanetti S, Donati A, et al. - Correlation between hyperglycemia and mortality in a medical and surgical intensive care unit. Minerva Anestesiol, 2005, 71, 717-725.
Ouattara A, Lecomte P, Le Manach Y, et al. - Poor intraoperative blood glucose control is associated with a worsened hospital outcome after cardiac surgery in diabetic patients. Anesthesiology, 2005, 103, 687-694.
Angus DC, Abraham E. - Intensive insulin therapy in critical illness. Am J Respir Crit Care Med, 2005, 172, 1358-1359.
Brunkhorst FM, Kuhnt E, Engel C, et al. - Intensive insulin therapy in patients with severe sepsis and septic shock is associated with an increased rate of hypoglycaemia - results from a randomized multicenter study. Infection, 2005, 33, 19.
McMullin J, Brozek J, Jaeschke R, et al. - Glycemic control in the ICU: a multicenter survey. Intensive Care Med, 2004, 30, 798-803.
Meijering S, Corstjens AM, Tulleken JE, et al. - Towards a feasible algorithm for tight glycaemic control in critically ill patients: a systematic review of the literature. Crit Care, 2006, 10, R19.
Preiser JC, Devos P. - Steps for the implementation and validation of tight glucose control. Intensive Care Med, 2007, 33, 570-571.
Kanji S, Buffie J, Hutton B, et al. - Reliability of point-of-care testing for glucose measurement in critically ill adults. Crit Care Med, 2005, 33, 2778-2785.
Brunkhorst FM, Wahl HG. - Blood glucose measurements in the critically ill : more than just a blood draw. Crit Care, 2006, 10, 178.
Devos Ph, Ledoux D, Preiser JC, on behalf of the GLU-CONTROL Steering Committee. - Current practice of glycaemia control in European intensive care units (ICUs). Intensive Care Med, 2005, 31, 130.
Egi M, Bellomo R, Stachowski E, et al. - Variability of blood glucose concentration and short-term mortality in critically ill patients. Anesthesiology, 2006, 105, 244-252.
Monnier L, Mas E, Ginet C, et al. - Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA, 2006, 295, 1681-1687.
Vriesendorp TM, van Santen S, DeVries JH, et al. - Predisposing factors for hypoglycemia in the intensive care unit. Crit Care Med, 2006, 34, 96-101.
Cryer PE. - Mechanisms of sympathoadrenal failure and hypoglycemia in diabetes. J Clin Invest, 2006, 116, 1470-1473.
Vriesendorp TM, Devries JH, van Santen S, et al. - Evaluation of short-term consequences of hypoglycemia in an intensive care unit. Crit Care Med, 2006, 34, 2714-2718.
Malhotra A. - Intensive insulin in intensive care. N Engl J Med, 2006, 354, 516-518.
Devos P, Preiser JC. - Is it time for implementation of tight glycaemia control by intensive insulin therapy in every ICU ? Crit Care, 2006, 10, 130.
Devos P, Chiolero R, Van den Berghe G, et al. - Glucose, insulin and myocardial ischaemia. Curr Opin Clin Nutr Metab Care, 2006, 9, 131-139.
Devos P, Preiser JC. - Tight blood glucose control: a recommendation applicable to any critically ill patient ? Crit Care, 2004, 8, 427-429.
Preiser JC, Devos P, Van den Berghe G. - Tight control of glycaemia in critically ill patients. Curr Opin Clin Nutr Metab Care, 2002, 5, 533-537.