[en] A case of malignant carotid body tumor with nodal, hepatic and bone metastases is reported. Carotid body chemodectomas are slow-growing tumors which invade local structures. These tumors are usually benign but can occasionally produce local and distant metastases. Development of metastatic localizations is the only formal proof of malignancy as histology cannot distinguish between benign and malignant chemodectomas. Bilateral carotid arteriography gives the diagnosis. Surgery is the basis of treatment and should be performed early in the course to limit operative complications. Radiotherapy can be given as adjuvant treatment.
Disciplines :
Cardiovascular & respiratory systems Surgery
Author, co-author :
DEFRAIGNE, Jean ; Centre Hospitalier Universitaire de Liège - CHU > Chirurgie cardio-vasculaire
Limet, Raymond ; Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique
Language :
French
Title :
Métastases ganglionnaires, hépatiques et osseuses d'un chemodectome carotidien. A propos d'un cas
Alternative titles :
[en] Lymphatic, Hepatic and Osseous Metastasis of a Carotid Chemodectoma. Apropos of a Case
Nora JD, Hallett JW, O'Brien PC, Naessens JM, Cherry KJ, Pairolero PC. Surgical resection of carotid body tumors : long-term survival, recurrence, and metastasis. Mayo Clin Proc 1988 ; 63 : 348-352.
Padberg FT, Gady B, Persson AV. Carotid body tumor, the Lahey Clinic experience. Am J Surg 1983 ; 145 ; 526.
Rosen IB, Palmer JA, Goldberg M, Mustard RA. Vascular problems associated with carotid body tumors. Am J Surg, 1981 ; 142 : 459-463.
Tashiro M, Nagase M, Akita S, Nemoto K. Malignant paraganglioma. Report of a case and review of the japanese literature. J Cranio Max Fac Surg 1988 ; 16 : 324-329.
Pacheco-Ojeda L, Durango L, Rodriquez C, Vivar N. Carotid body tumor at high altitudes. World J Surg 1988 ; 12 : 856-860.
Grufferman S, Gillman MW, Pasternak LR, Peterson CL, Young WG. Familial carotid body tumors. Case report and epidemiologic review. Cancer 1980 ; 46 : 2116-22.
Bosq J, Caillaud J, Icheau C, Luboinski B, Marandas P, Richard JM. Etude anatomo-pathologique des paragangliomes cervico-céphaliques. Actualités de carcinologie cervico-faciale, vol 10, Paris, Masson, 1984, p 27.
Barnes L, Taylor SR. Carotid body paragangliomas. Arch Otolaryngol Head Neck Surg 1990 ; 116 : 447-453.
Gaylis H, Mieny CJ. The incidence of malignancy in carotid body tumors. Br J Surg 1977 ; 64 : 885-89.
Mc Pherson GAD, Halliday AW, Mansfield AO. Carotid body tumours and other cervical paragaangliomas. Diagnosis and management in 25 patients. Br J Surg 1989 ; 76 : 33-36.
Smith RF, Shetty PC, Reddy DJ. Surgical treatment of carotid paragangliomas presenting unusual technical difficulties. The value of preoperative embolization. J Vasc Surg 1988 ; 7 : 631-6.
Konefal JB, Pilepich MV, Spector GJ, Perez CA. Radiation therapy in the treatment of chemodectomas. Laryngoscope, 1987 ; 97 : 1331-1335.
Valdagni R, Amichetti M. Radiation therapy of carotid body tumors. Am J Clin Oncol 1990 ; 13 : 45-48.
Shepard RC, Lopez W, Robert NJ. Chemotherapy of glomus jugulare tumors. World J Surg 1988 ; 12 : 1202-1203.