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Tomographie a emission de positons dans l'evaluation de l'extension ganglionnaire intrathoracique du cancer bronchique non petites cellules. Etude preliminaire chez 30 patients.
Bury, Thierry; CORHAY, Jean-Louis; Paulus, P et al.
1996In Revue des Maladies Respiratoires, 13 (3), p. 281-286
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Keywords :
Adult; Aged; Carcinoma, Non-Small-Cell Lung/pathology/radionuclide imaging; Deoxyglucose/analogs & derivatives/diagnostic use; Female; Fluorine Radioisotopes/diagnostic use; Fluorodeoxyglucose F18; Humans; Lung Neoplasms/pathology/radionuclide imaging; Lymph Nodes/pathology/radionuclide imaging; Magnetic Resonance Imaging; Male; Mediastinoscopy; Mediastinum/pathology/radionuclide imaging; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Thoracotomy; Tomography, Emission-Computed; Tomography, X-Ray Computed
Abstract :
[en] Current methods for evaluating the mediastinum include chest radiography, computed tomography (CT) or magnetic resonance (MR) imaging and mediastinoscopy. Despite advances in morphologic imaging, some lung cancer patients are found to have unresectable disease at surgery. In contrast to CT scan or MR imaging, which depend primarily on anatomic and morphological criteria, positron emission tomography (PET) with 18fluorodeoxyglucose (FDG) depends mainly of the metabolic characteristics of a tissue for the diagnosis of disease. We perform a prospective study to compare FDG-PET and CT of the thorax in the presurgical assessment of the mediastinum in patients with newly diagnosed non-small cell lung cancer. Thirty patients have been included. CT and PET-scans were interpreted separately and results were compared to surgical staging during thoracotomy. In assessing mediastinal involvement, CT scan had a sensitivity of 56% and a specificity of 64%. For diagnosis mediastinal nodal disease, FDG-PET was 87% sensitive and 78% specific. Its positive predictive value was 82%, and the negative value was 83%. In conclusion, our preliminary results show that FDG-PET appears more accurate than CT in staging of mediastinal non-small cell lung cancer.
Disciplines :
Public health, health care sciences & services
Surgery
Cardiovascular & respiratory systems
Author, co-author :
Bury, Thierry ;  Université de Liège - ULiège > Département des sciences de la motricité > Physiologie humaine et physiologie de l'effort physique
CORHAY, Jean-Louis ;  Centre Hospitalier Universitaire de Liège - CHU > Pneumologie-Allergologie
Paulus, P
Weber, T
D'Harcour, J B
Limet, Raymond ;  Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique
Rigo, Pierre ;  Université de Liège - ULiège > Département des sciences de la motricité > Département des sciences de la motricité
Radermecker, Maurice ;  Université de Liège - ULiège
Language :
French
Title :
Tomographie a emission de positons dans l'evaluation de l'extension ganglionnaire intrathoracique du cancer bronchique non petites cellules. Etude preliminaire chez 30 patients.
Alternative titles :
[en] Positron emission tomography in the evaluation of intrathoracic lymphatic extension of non-small cell bronchial cancer. A preliminary study of 30 patients
Publication date :
1996
Journal title :
Revue des Maladies Respiratoires
ISSN :
0761-8425
eISSN :
1776-2588
Publisher :
Elsevier Masson, Paris, France
Volume :
13
Issue :
3
Pages :
281-286
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 01 August 2012

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