Article (Scientific journals)
When should we measure vitamin D concentration in clinical pratice?
Souberbielle, Jean-Claude; Courbebaisse, Marie; Cormier, Catherine et al.
2012In Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum, 72 (suppl 243), p. 129-135
Peer Reviewed verified by ORBi
 

Files


Full Text
When should we measure Vitamin D concentration.pdf
Publisher postprint (107.18 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
25-hydroxyvitamin D; osteoporosis; chronic kidney disease; vitamin D deficiency
Abstract :
[en] The many recently published data on vitamin D have raised much interest in the medical community. One of the consequences has been a great increase in the prescription of vitamin D concentration measurements in clinical practice. It must be reminded that only the measurement of 25-hydroxyvitamin D (25(OH)D) concentration is indicated to evaluate vitamin D status. Furthermore, since vitamin D insuffi ciency is so common, since treatment is inexpensive and has a large safety margin, and since we already have much data suggesting that besides its classic effects on bone and mineral metabolism, vitamin D may potentially be helpful for the prevention/management of several diseases, perhaps should it be prescribed to everyone without prior testing? In our opinion, there are however groups of patients in whom estimation of vitamin D status is legitimate and may be recommended. This includes patients in whom a “ reasonably ” evidence-based target concentration (i.e., based on randomized clinical trials when possible) should be achieved and/or maintained such as patients with rickets/osteomalacia, osteoporosis, chronic kidney disease and kidney transplant recipients, malabsorption, primary hyperparathyroidism, granulomatous disease, and those receiving treatments potentially inducing bone loss. Other patients in whom vitamin D concentration may be measured are those with symptoms compatible with a severe vitamin D defi ciency or excess persisting without explanation such as those with diffuse pain, or elderly individuals who fall, or those receiving treatments which modify vitamin D metabolism such as some anti-convulsants. Measurement of Vitamin D concentrations should also be part of any exploration of calcium/phosphorus metabolism which includes measurement of serum calcium, phosphate and PTH.
Disciplines :
Laboratory medicine & medical technology
Author, co-author :
Souberbielle, Jean-Claude
Courbebaisse, Marie
Cormier, Catherine
Pierrot-Deseilligny, Charles
Viard, Jean-Paul
Jean, Guillaume
CAVALIER, Etienne  ;  Centre Hospitalier Universitaire de Liège - CHU > Chimie médicale
Language :
English
Title :
When should we measure vitamin D concentration in clinical pratice?
Publication date :
April 2012
Journal title :
Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum
ISSN :
0085-591X
Publisher :
Universitetsforlaget, Oslo, Norway
Volume :
72
Issue :
suppl 243
Pages :
129-135
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 30 May 2012

Statistics


Number of views
83 (12 by ULiège)
Number of downloads
8 (4 by ULiège)

Bibliography


Similar publications



Contact ORBi