[en] The comparison of organolanthanide complexes, (C5Me5)(2)SmMe(THF) (Sm1) and [(C5Me5)(2)SM](2)(PhC=C=C=CPh) (Sm2), with tin compounds, Bu2Sn(OMe), (Sn1) and Bu2Sn(OCH2CH2CH2O) (Sn2), in the preparation of random, diblock, and triblock copolymers composed Of L-lactide (L-LA) or D,L-LA and cyclic carbonates, trimethylene carbonate (TMC) or 2,2-dimethyltrimethylene carbonate (DTC) is reported. The biodegradabilities of the resulting copolymers with proteinase K and a compost were examined. The copolymerization of L-LA with cyclic carbonates by Sm1 or Sm2 afforded copolymers with relatively low melting points (< 160 degrees C) due to the accompanying epimerization in comparison with those obtained with Su1 or Sn2. In the degradation of the polymers with a compost, the copolymers based on D, L-LA were more degradable than those based on L-LA. On the other hand, the effect of the incorporated cyclic carbonate on its degradability was more drastic in the copolymers based on L-LA than those in the copolymers based on D, L-LA. The introduction of only a small amount of the cyclic carbonates into PLLA significantly enhanced the degradability of PLLA with a compost or proteinase K. In the enzymatic degradation of L-LA-containing polymers, the copolymerization of L-LA with TMC was also quite effective to improve the degradability of PLLA. Triblock copolymerization tends to be effective to enhance the degradability of PLLA.
Research Center/Unit :
Center for Education and Research on Macromolecules (CERM)
Disciplines :
Chemistry Materials science & engineering
Author, co-author :
Nakayama, Yuushou; Hiroshima University
Yasuda, Hajime; Hiroshima University
Yamamoto, Katsuhiro; Hiroshima University
Tsutsumi, Chikara; Niihama National College of Technology
Jérôme, Robert ; Université de Liège - ULiège > Centre d'études et de rech. sur les macromolécules (CERM)
Lecomte, Philippe ; Université de Liège - ULiège > Centre d'études et de rech. sur les macromolécules (CERM)
Language :
English
Title :
Comparison of Sm complexes with Sn compounds for syntheses of copolymers composed of lactide and cyclic carbonates and their biodegradabilities
NEDO - New Energy and Industrial Technology Development Organization BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique F.R.S.-FNRS - Fonds de la Recherche Scientifique
Commentary :
The authors acknowledge Reactive & Functional Polymers (Elsevier) for allowing them to archive this paper.
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
Bibliography
J. Kleine, and H. Kleine Makromol. Chem. 30 1959 30
R.K. Kurkani, E.G. Moore, A. Hegyeli, and F. F.Leonard J. Biomed. Mater. Res. 5 1971 169
I. Ohkoshi, H. Abe, and Y. Doi Polymer 41 2000 5985
R.H. Wehrenberg Mater. Eng. 3 1981 61
K. Kishore, R. Vasanthakumari, and A.J. Pennings J. Polym. Sci. Part B. Polym. Phys. 22 1984 537
E. Eling, S. Gogolewski, and A. Pennings J. Polymer 23 1982 1587
S. Gogolewski, and A.J. Pennings J. Appl. Polym. Sci. 28 1983 1045
J.W. Leenslag, S. Gogolewski, and A.J. Pennings J. Appl. Polym. Sci. 29 1984 2829
M.G. Dunn, and L.D. Bellincmpi J. Biomed. Mater. Res. 58 1995 1423
A. Smith, and I.M. Hunnyball Int. J. Pharmaceutics 30 1986 215
Z. Zhang, D. Grijpma, and W. Feijen J. Macromol. Chem. Phys. 205 2004 867
A.P. Pego, M.J.A. Van Luyn, L.A. Brouwer, P.B. van Wachem, A.A. Poot, D.W. Grijpma, and J. Feijen J. Biomed. Mater. Res., Part A 67A 2003 1044
S. Agarwal, and M. Puchner Eur. Polym. J. 38 2002 2365
J.-H. Kim, and J.H. Lee Macromol. Res. 10 2003 54
J.-H. Kim, and J.H. Lee Polym. J. 34 2002 203
J.-H. Kim, S.Y. Lee, and D.J. Chung Polym. J. 32 2000 1056
V. Simic, S. Pensec, and N. Spassky Macromol. Symp. 153 2000 109
C. Tsutsumi, and H.J. Yasuda Polym. Sci.: Part A: Polym. Chem. 39 2001 3916
C. Tsutsumi, K. Nakagawa, H. Shirahama, and H. Yasuda Macromol. Biosci. 28 2002 223
C. Tsutsumi, K. Nakagawa, H. Shirahama, and H. Yasuda Polym. Int. 2003 52
A.P. Pego, B. Siebum, M.J.A. Van Luyn, X.J. Gallegoy Van Seijen, A.A. Poot, D.W. Grijpma, and J. Feijen Tissue Eng. 9 2003 981
A.P. Pego, A.A. Poot, D.W. Grijpma, and J. Feijen J. Mater. Sci. Mater. Med. 14 2003 767
F. Meng, C. Hiemstra, G.H.M. Engbers, and J. Feijen Macromolecules 36 2003 3004
C. Tsutsumi, K. Yamamoto, A. Ichimaru, M. Nodono, K. Nakagawa, and H. Yasuda J. Polym. Sci.: Part A: Polym. Chem. 41 2003 3572
H. Yasuda, K. Yamamoto, Y. Nakayama, C. Tsutsumi, P. Lecomte, R.J.S. McCarthy, and D. Kaplan React. Funct. Polym. 61 2004 277
F.E. Kohn, J.G.V. Ommen, and J. Feijen Eur. Polym. J. 19 1983 1081
F.E. Kohn, J.W.v. Berg, G.v.d. Ridder, and J. Feijen J. Appl. Polym. Sci. 29 1984 4265
H.R. Kricheldorf, and A. Serra Polym. Bull. 14 1985 497
J. Dahlmann, G. Rafler, K. Fechner, and B. Mehlis Brit. Polym. J. 23 1990 235
X. Zhang, U.P. Wyss, D. Pichora, and M.F. Goosen Polym. Bull. 27 1992 623
G. Scwach, J. Coudane, R. Engel, and M. Vert Polym. Bull. 32 1994 617
W.J. Evans, L.R. Chamberlain, T.A. Ulibarri, and J.W. Ziller J. Am. Chem. Soc. 110 1988 6423
W.J. Evans, R.A. Keyer, H. Zhang, and J.L. Atwood J. Chem. Soc. Chem. Commun. 1987 837
H.R. Kricheldorf, S.-R. Lee, and N. Schittenhelm Macromol. Chem. Phys. 199 1998 273
L.S. Boffa, and B.M. Novak Macromolecules 27 1994 6993
H.R. Kricheldorf, and A. Stricker Macromol. Chem. Phys. 200 1999 1726
This website uses cookies to improve user experience. Read more
Save & Close
Accept all
Decline all
Show detailsHide details
Cookie declaration
About cookies
Strictly necessary
Performance
Strictly necessary cookies allow core website functionality such as user login and account management. The website cannot be used properly without strictly necessary cookies.
This cookie is used by Cookie-Script.com service to remember visitor cookie consent preferences. It is necessary for Cookie-Script.com cookie banner to work properly.
Performance cookies are used to see how visitors use the website, eg. analytics cookies. Those cookies cannot be used to directly identify a certain visitor.
Used to store the attribution information, the referrer initially used to visit the website
Cookies are small text files that are placed on your computer by websites that you visit. Websites use cookies to help users navigate efficiently and perform certain functions. Cookies that are required for the website to operate properly are allowed to be set without your permission. All other cookies need to be approved before they can be set in the browser.
You can change your consent to cookie usage at any time on our Privacy Policy page.