Chronic Fatigue Syndrome: A Systematic Review

[en] OBJECTIVE: A systematic review of the literature about chronic fatigue syndrome (CFS). METHODS: A search of the Medline database (via Ovid and PubMed) with the key words chronic fatigue syndrome, diagnosis, classification, epidemiology, etiology, physiopathology, metabolism, microbiology, immunology, virology, psychology, drug therapy, rehabilitation, and therapy. The reference lists of each article were examined for additional related articles. RESULTS: CFS was defined in 1988 by the US Centes for Disease Control and Prevention. The prevalence of chronic fatigue syndrome has ranged from 0.2% to 0.7% in the general population. In 1994, the definition of CFS was revised by Fukuda et al. Despite various research in several topics (e.g. infection, immune systems, neuroendocrinology, autonomic activity, neuromuscular involvement), the pathophysiology remains unknown. CONCLUSION: CFS, with its various major clinical and functional impacts, should be associated with a "biopsychosocial model". Progressive muscular rehabilitation, combined with behavioral and cognitive treatment, is an essential part of therapy.

Disciplines :

Orthopedics, rehabilitation & sports medicine

Author, co-author :

Maquet, Didier ; Université de Liège - ULiège > Département des sciences de la motricité > Département des sciences de la motricité

Demoulin, Christophe ; Université de Liège - ULiège > Département des sciences de la motricité > Kinésithérapie spécifique et réadaptation motrice

Crielaard, Jean-Michel ; Université de Liège - ULiège > Département des sciences de la motricité > Evaluation et entraînement des aptitudes physiques

Language :

English

Title :

Chronic Fatigue Syndrome: A Systematic Review

Publication date :

July 2006

Journal title :

Annales de Réadaptation et de Médecine Physique

ISSN :

0168-6054

Publisher :

Elsevier, Netherlands

Volume :

Issue :

Pages :

418-427

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 05 May 2009

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94 (5 by ULiège)

Number of downloads

3 (1 by ULiège)

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