[en] Little is known about the ability to enumerate small numbers of successive stimuli and movements. It is possible that there exist neural substrates that are consistently recruited both to count sensory stimuli from different modalities and for counting movements executed by different effectors. Here, we identify a network of areas that was involved in enumerating small numbers of auditory, visual, and somatosensory stimuli, and in enumerating sequential movements of hands and feet, in the bilateral premotor cortex, presupplementary motor area, posterior temporal cortex, and thalamus. The most significant consistent activation across sensory and motor counting conditions was found in the lateral premotor cortex. Lateral premotor activation was not dependent on movement preparation, stimulus presentation timing, or number word verbalization. Movement counting, but not sensory counting, activated the anterior parietal cortex. This anterior parietal area may correspond to an area recruited for movement counting identified by recent single-neuron studies in monkeys. These results suggest that overlapping but not identical networks of areas are involved in counting sequences of sensory stimuli and sequences of movements in the human brain.
Disciplines :
Neurosciences & behavior Radiology, nuclear medicine & imaging
Author, co-author :
Kansaku, Kenji; bDivision of Cerebral Integration, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki 444-8585, Japan
Johnson, Ari; Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
Grillon, Marie-Laure; Division of Cerebral Integration, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki 444-8585, Japan
Garraux, Gaëtan ; Université de Liège - ULiège & Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
Sadato, Norihiro; bDivision of Cerebral Integration, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki 444-8585, Japan
Hallett, Mark; Human Motor Control Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
Language :
English
Title :
Neural correlates of counting of sequential sensory and motor events in the human brain.
Publication date :
2006
Journal title :
NeuroImage
ISSN :
1053-8119
eISSN :
1095-9572
Publisher :
Elsevier Science, Orlando, United States - Florida
Atkinson J., Campbell F.W., and Francis M.R. The magic number 4 +/- 0: a new look at visual numerosity judgements. Perception 5 (1976) 327-334
Barth H., Kanwisher N., and Spelke E. The construction of large number representations in adults. Cognition 86 (2003) 201-221
Catalan M.J., Honda M., Weeks R.A., Cohen L.G., and Hallett M. The functional neuroanatomy of simple and complex sequential finger movements: a PET study. Brain 121 Pt. 2 (1998) 253-264
Chochon F., Cohen L., van de Moortele P.F., and Dehaene S. Differential contributions of the left and right inferior parietal lobules to number processing. J. Cogn. Neurosci. 11 (1999) 617-630
Duhamel J.R., Bremmer F., BenHamed S., and Graf W. Spatial invariance of visual receptive fields in parietal cortex neurons. Nature 389 (1997) 845-848
Eger E., Sterzer P., Russ M.O., Giraud A.L., and Kleinschmidt A. A supramodal number representation in human intraparietal cortex. Neuron 37 (2003) 719-725
Feigenson L., Dehaene S., and Spelke E. Core systems of number. Trends Cogn. Sci. 8 (2004) 307-314
Fias W., and Verguts T. The mental number line: exact and approximate. Trends Cogn. Sci. 8 (2004) 447-448 (author reply 448-449)
Friston K.J., Holmes A.P., Worsley K.J., Poline J.B., Frith C.D., and Frackowiak R.S.J. Statistical parametric maps in functional imaging: a general linear approach. Human Brain Map. 2 (1995) 189-210
Gallistel C.R., and Gelman R. Non-verbal numerical cognition: from reals to integers. Trends Cogn. Sci. 4 (2000) 59-65
Garraux G., McKinney C., Wu T., Kansaku K., Nolte G., and Hallett M. Shared brain areas but not functional connections controlling movement timing and order. J. Neurosci. 25 (2005) 5290-5297
Gelman R., and Butterworth B. Number and language: how are they related?. Trends Cogn. Sci. 9 (2005) 6-10
Gelman R., and Gallistel C.R. The Child's Understanding of Number (1978), Harvard Univ. Press, Cambridge
Gordon P. Numerical cognition without words: evidence from Amazonia. Science 306 (2004) 496-499
Grafton S.T., Hazeltine E., and Ivry R.B. Abstract and effector-specific representations of motor sequences identified with PET. J. Neurosci. 18 (1998) 9420-9428
Graziano M.S., and Gandhi S. Location of the polysensory zone in the precentral gyrus of anesthetized monkeys. Exp. Brain Res. 135 (2000) 259-266
Hauser M.D., Carey S., and Hauser L.B. Spontaneous number representation in semi-free-ranging rhesus monkeys. Proc. R. Soc. London, Ser. B Biol. Sci. 267 (2000) 829-833
Huang J., Carr T.H., and Cao Y. Comparing cortical activations for silent and overt speech using event-related fMRI. Hum. Brain Mapp. 15 (2002) 39-53
Jordan K.E., Brannon E.M., Logothetis N.K., and Ghazanfar A.A. Monkeys match the number of voices they hear to the number of faces they see. Curr. Biol. 15 (2005) 1034-1038
Kahneman D., Treisman A., and Gibbs B.J. The reviewing of object files: object-specific integration of information. Cognit. Psychol. 24 (1992) 175-219
Kansaku K., Yamaura A., and Kitazawa S. Sex differences in lateralization revealed in the posterior language areas. Cereb. Cortex 10 (2000) 866-872
Kansaku K., Hanakawa T., Wu T., and Hallett M. A shared neural network for simple reaction time. NeuroImage 22 (2004) 904-911
Kansaku K., Carver B., Johnson A., Matsuda K., and Hallett M. Role of the left premotor cortex for large number counting. Abstract Viewer/Itinerary Planner Washington, DC: Society for Neuroscience: Program No. 819.11 (2004)
Kansaku K., Muraki S., Umeyama S., Nishimori Y., Kochiyama T., Yamane S., and Kitazawa S. Cortical activity in multiple motor areas during sequential finger movements: an application of independent component analysis. NeuroImage 28 (2005) 669-681
Lee K.M. Cortical areas differentially involved in multiplication and subtraction: a functional magnetic resonance imaging study and correlation with a case of selective acalculia. Ann. Neurol. 48 (2000) 657-661
Meck W.H., and Church R.M. A mode control model of counting and timing processes. J. Exp. Psychol. Anim. Behav. Processes 9 (1983) 320-334
Menon V., Rivera S.M., White C.D., Glover G.H., and Reiss A.L. Dissociating prefrontal and parietal cortex activation during arithmetic processing. NeuroImage 12 (2000) 357-365
Nieder A. The number domain-Can we count on parietal cortex?. Neuron 44 (2004) 407-409
Nieder A. Counting on neurons: the neurobiology of numerical competence. Nat. Rev., Neurosci. 6 (2005) 177-190
Nieder A., and Miller E.K. A parieto-frontal network for visual numerical information in the monkey. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 7457-7462
Ogawa S., Menon R.S., Tank D.W., Kim S.G., Merkle H., Ellermann J.M., and Ugurbil K. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. A comparison of signal characteristics with a biophysical model. Biophys. J. 64 (1993) 803-812
Ojemann G.A. Mental arithmetic during human thalamic stimulation. Neuropsychologia 12 (1974) 1-10
Oldfield R.C. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 9 (1971) 97-113
Penfield W., and Welch K. The supplementary motor area of the cerebral cortex. Arch. Neurol. Psychiatr. 66 (1951) 289-317
Piazza M., Mechelli A., Butterworth B., and Price C.J. Are subitizing and counting implemented as separate or functionally overlapping processes?. NeuroImage 15 (2002) 435-446
Piazza M., Izard V., Pinel P., Le Bihan D., and Dehaene S. Tuning curves for approximate numerosity in the human intraparietal sulcus. Neuron 44 (2004) 547-555
Price C.J., and Friston K.J. Cognitive conjunction: a new approach to brain activation experiments. NeuroImage 5 (1997) 261-270
Rickard T.C., Romero S.G., Basso G., Wharton C., Flitman S., and Grafman J. The calculating brain: an fMRI study. Neuropsychologia 38 (2000) 325-335
Roland P.E., Larsen B., Lassen N.A., and Skinhoj E. Supplementary motor area and other cortical areas in organization of voluntary movements in man. J. Neurophysiol. 43 (1980) 118-136
Sadato N., Campbell G., Ibanez V., Deiber M., and Hallett M. Complexity affects regional cerebral blood flow change during sequential finger movements. J. Neurosci. 16 (1996) 2691-2700
Sathian K., Simon T.J., Peterson S., Patel G.A., Hoffman J.M., and Grafton S.T. Neural evidence linking visual object enumeration and attention. J. Cogn. Neurosci. 11 (1999) 36-51
Sawamura H., Shima K., and Tanji J. Numerical representation for action in the parietal cortex of the monkey. Nature 415 (2002) 918-922
Schubotz R.I., and von Cramon D.Y. Functional-anatomical concepts of human premotor cortex: evidence from fMRI and PET studies. NeuroImage 20 Suppl. 1 (2003) S120-S131
Shuman M., and Kanwisher N. Numerical magnitude in the human parietal lobe; tests of representational generality and domain specificity. Neuron 44 (2004) 557-569
Simon T. Reconceptualizing the origins of number knowledge: a "Non-Numerical" account. Cogn. Dev. 12 (1997) 349-372
Simon O., Mangin J.F., Cohen L., Le Bihan D., and Dehaene S. Topographical layout of hand, eye, calculation, and language-related areas in the human parietal lobe. Neuron 33 (2002) 475-487
Spielman D.M., Adalsteinsson E., and Lim K.O. Quantitative assessment of improved homogeneity using higher-order shims for spectroscopic imaging of the brain. Magn. Reson. Med. 40 (1998) 376-382
Starkey P., and Cooper Jr. R.G. Perception of numbers by human infants. Science 210 (1980) 1033-1035
Starkey P., Spelke E.S., and Gelman R. Numerical abstraction by human infants. Cognition 36 (1990) 97-127
Talairach J., and Tournoux P. Co-planer Stereotaxic Atlas of the Human Brain: 3-Dimensional Proportional system: An Approach to Cerebral Imaging (1988), Thieme, New York
Tanji J. Sequential organization of multiple movements: involvement of cortical motor areas. Annu. Rev. Neurosci. 24 (2001) 631-651
Trick L.M., and Pylyshyn Z.W. Why are small and large numbers enumerated differently? A limited-capacity preattentive stage in vision. Psychol. Rev. 101 (1994) 80-102
Wynn K. Addition and subtraction by human infants. Nature 358 (1992) 749-750
Xu F., and Spelke E.S. Large number discrimination in 6-month-old infants. Cognition 74 (2000) B1-B11