[en] Why does moderate exposure to a drug reward make natural rewards increasingly attractive to
organisms, whereas prolonged exposure to the same drug reward has the opposite effect? The paradox behind that question remains unsatisfactorily captured by current theories of addiction. The incentivesensitisation theory is viewed as a promising approach to this paradox, although it provides no mechanism to explain the decrease in interest of natural rewards as time exposure to a drug increases. To attempt to remedy this problem, I describe a model called the anticipatory dynamics model (ADM) that suggests a pivotal role of anticipation and attention inmotivational interactions. In addition to relying on strong neuropsychopharmacological data, the ADM provides an original conception of motivational specificity. The ADM is an extension of the incentive-sensitisation theory that hypothesizes how drugs interact with natural rewards. It has not been tested empirically, although a possible experiment to test two predictions in the field of addiction is presented.
Disciplines :
Neurosciences & behavior
Author, co-author :
Anselme, Patrick ; Université de Liège - ULiège > Département des sciences cognitives > Neuroscience comportementale et psychopharmacologie expér.
Language :
English
Title :
The effect of exposure to drugs on the processing of natural rewards
Publication date :
2009
Journal title :
Neuroscience and Biobehavioral Reviews
ISSN :
0149-7634
eISSN :
1873-7528
Publisher :
Pergamon Press, New York, United States - New York
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
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