Article (Scientific journals)
The cognitive modulation of pain: hypnosis- and placebo-induced analgesia.
Kupers, Ron; Faymonville, Marie-Elisabeth; Laureys, Steven
2005In Progress in Brain Research, 150, p. 251-69
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Keywords :
Analgesia/methods; Cognition; Humans; Hypnosis; Pain/physiopathology/psychology; Placebos/therapeutic use
Abstract :
[en] Nowadays, there is compelling evidence that there is a poor relationship between the incoming sensory input and the resulting pain sensation. Signals coming from the peripheral nervous system undergo a complex modulation by cognitive, affective, and motivational processes when they enter the central nervous system. Placebo- and hypnosis-induced analgesia form two extreme examples of how cognitive processes may influence the pain sensation. With the advent of modern brain imaging techniques, researchers have started to disentangle the brain mechanisms involved in these forms of cognitive modulation of pain. These studies have shown that the prefrontal and anterior cingulate cortices form important structures in a descending pathway that modulates incoming sensory input, likely via activation of the endogenous pain modulatory structures in the midbrain periaqueductal gray. Although little is known about the receptor systems involved in hypnosis-induced analgesia, studies of the placebo response suggest that the opiodergic and dopaminergic systems play an important role in the mediation of the placebo response.
Disciplines :
Alternative medicine
Author, co-author :
Kupers, Ron;  Rigshospitalet Copenhagen, Denmark > PET unit and section of surgical pathophysiology
Faymonville, Marie-Elisabeth ;  Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
Laureys, Steven  ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Language :
Title :
The cognitive modulation of pain: hypnosis- and placebo-induced analgesia.
Publication date :
Journal title :
Progress in Brain Research
Publisher :
Elsevier, Amsterdam, Netherlands
Volume :
Pages :
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 31 January 2012


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