Reference : Traitement de la maladie de Parkinson en 2009.
Scientific journals : Article
Human health sciences : Neurology
Traitement de la maladie de Parkinson en 2009.
[en] Management of Parkinson's disease in 2009
MAERTENS DE NOORDHOUT, Alain mailto [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie CHR]
Revue Médicale Suisse
Yes (verified by ORBi)
[en] Antiparkinson Agents/administration & dosage/adverse effects ; Deep Brain Stimulation/methods ; Dopamine Agonists/administration & dosage/adverse effects ; Drug Therapy, Combination ; Dyskinesia, Drug-Induced/etiology ; Humans ; Levodopa/administration & dosage/adverse effects ; Parkinson Disease/drug therapy/surgery/therapy ; Primary Dysautonomias/drug therapy ; Prognosis ; Risk Factors
[en] The cause of Parkinson's disease remains unknown and no cure or prevention exists so far. Levodopa remains by far the most potent symptomatic therapy, but induces side-effects such as motor fluctuations and abnormal movements, which can somewhat be counterbalanced by optimizing levodopa plasma levels or acting at receptors level with long half-life dopamine agonists. In severe cases, functional surgery with deep brain stimulation can be offered. Some non-dopaminergic symptoms like dementia, freezing, postural instability or dysautonomia do not respond to dopaminergic drugs and need special care.

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