The inseminating bull and plasma pregnancy-associated glycoprotein levels were related to peripheral leukocyte counts during the late pregnancy/early postpartum period in high-producing dairy cows.

Abdelfatah-Hassan, A.; Almeria, S.; Serrano, B.; Melo de Sousa, Noelita; Beckers, Jean-François; Lopez-Gatius, F.

doi:10.1016/j.theriogenology.2011.11.002

Article (Scientific journals)

The inseminating bull and plasma pregnancy-associated glycoprotein levels were related to peripheral leukocyte counts during the late pregnancy/early postpartum period in high-producing dairy cows.

Abdelfatah-Hassan, A.; Almeria, S.; Serrano, B. et al.

2012 • In Theriogenology, 77 (7), p. 1390-1397

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/107328

DOI
10.1016/j.theriogenology.2011.11.002

PubMed
22225694

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Keywords :

Sire effect; Pregnancy-associated glycoproteins; White blood cell count; Peripartum immunity; Dairy cattle

Abstract :

[en] The interest in the immunology and endocrinology aspects of the peripartum in dairy cows has been increasing in the last years, since the animal status during the pre- and postpartum period determines the subsequent productive and reproductive performance of the animal. At parturition, a drop in the immune functions of the peripheral blood polymorph-nuclear cells (PMN) was observed after a peak of Pregnancy-Associated Glycoproteins (PAGs) and recently, the inseminating bull was found to affect the plasma levels of bovine Pregnancy-Associated Glycoproteins (bovine PAGs) in the pregnant Holstein-Friesian dairy cows. The present work was aimed to determine whether changes in leukocyte counts during the peripartum, indicative of the animal immune status, could be related to the inseminating bull and to the levels of plasma pregnancy-associated glycoproteins (PAGs). Ninety six clinically healthy, single pregnant cows were selected in a commercial dairy herd. Six blood samples (four prepartum and two postpartum) were obtained every two weeks, and total and differential blood cell counts were analyzed. Based on procedures of General Linear Model analysis of variance for repeated measures, the inseminating bull affected counts of total leukocytes and lymphocytes (P<0.001; between-subject effects) throughout the peripartum period. In addition, cows with high plasma levels of PAGs (>900 ρg/µL) on Day 262-268 of gestation had higher numbers of total leukocytes and neutrophils throughout the peripartum period (P<0.001; between-subject effects). Young animals (≤ 1 lactation) had higher total leukocyte and lymphocytes counts than older cows (two or more lactations) throughout the study period. These results showed a clear relationship between the inseminating bull and plasma PAG levels and peripheral leukocyte counts during the peripartum period of dairy cows.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Abdelfatah-Hassan, A.

Almeria, S.

Serrano, B.

Melo de Sousa, Noelita ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction

Beckers, Jean-François ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction

Lopez-Gatius, F.

Language :

English

Title :

The inseminating bull and plasma pregnancy-associated glycoprotein levels were related to peripheral leukocyte counts during the late pregnancy/early postpartum period in high-producing dairy cows.

Publication date :

15 April 2012

Journal title :

Theriogenology

ISSN :

0093-691X

eISSN :

1879-3231

Publisher :

Elsevier

Volume :

Issue :

Pages :

1390-1397

Peer reviewed :

Peer Reviewed verified by ORBi

Funders :

Spanish CICYT grants AGL2010-21273-C01/GAN and AGL2010-21273-C02/GAN. Spanish Ministry of Science and Innovation, MICINN, BES-2008-9883

Available on ORBi :

since 09 January 2012

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Dunklee J.S., Freeman A.E., Kelley D.H. Comparison of Holsteins selected for high and average milk production. 1. Net income and production response to selection for milk. J Dairy Sci 1994, 77:1890-1896.
Glantz M., Månsson H.L., Stålhammar H., Bårström L.O., Fröjelin M., Knutsson A., Teluk C., Paulsson M. Effects of animal selection on milk composition and processability. J Dairy Sci 2009, 92:4589-4603.
Bulman D.C. A possible influence of the bull on the incidence of embryonic mortality in cattle. Vet Rec 1979, 105:420-422.
Sakaguchi M., Geshi M., Hamano S., Yonai M., Nagai T. Embryonic and calving losses in bovine mixed-breed twins induced by transfer of in vitro-produced embryos to bred recipients. Anim Reprod Sci 2002, 72:209-221.
López-Gatius F., Santolaria P., Yániz J., Rutllant J., López-Béjar M. Factors affecting pregnancy loss from gestation Day 38 to 90 in lactating dairy cows from a single herd. Theriogenology 2002, 57:1251-1261.
López-Gatius F., Szenci O., Bech-Sàbat G., García-Ispierto I., Serrano B., Santolaria P., et al. Factors of non-infectious nature affecting late embryonic and early foetal loss in high producing dairy herds in north-eastern Spain. Magy Allatorv Lapja 2009, 131:515-531.
Joosten I., Van Eldik P., Elving L., Van D.M. Factors affecting occurrence of retained placenta in cattle. Effect of sire on incidence. Anim Reprod Sci 1991, 25:11-22.
Guilbault L.A., Roy G.L., Beckers J.F., Dufour J.J. Influence of breed of fetus on periparturient endocrine responses and subsequent milk production of Ayrshire dams. J Dairy Sci 1990, 73:2766-2773.
Reynolds W.L., Urick J.J., Knapp B.W. Biological type effects on gestation length, calving traits and calf growth rate. J Anim Sci 1990, 68:630-639.
Maltecca C., Khatib H., Schutzkus V.R., Hoffman P.C., Weigel K.A. Changes in conception rate, calving performance, and calf health and survival from the use of crossbred Jersey x Holstein sires as mates for Holstein dams. J Dairy Sci 2006, 89:2747-2754.
Kehrli M.E., Weigel K.A., Freeman A.E., Thurston J.R., Kelley D.H. Bovine sire effects on daughters' in vitro blood neutrophil functions, lymphocyte blastogenesis, serum complement and conglutinin levels. Vet Immunol Immunopathol 1991, 27:303-319.
Detilleux J.C., Kehrli M.E., Stabel J.R., Freeman A.E., Kelley D.H. Study of immunological dysfunction in periparturient Holstein cattle selected for high and average milk production. Vet Immunol Immunopathol 1995, 44:251-267.
Kazmer G.W., Barnes M.A., Akers R.M., Pearson R.E. Effect of genetic selection for milk yield and increased milking frequency on plasma growth hormone and prolactin concentration in Holstein cows. J Anim Sci 1986, 63:1220-1227.
Beerepoot G.M., Freeman A.E., Detilleux J.C. Effect of season, genetic line, and sire on growth concentrations of somatotropin in serum of Holstein cows in early lactation. J Dairy Sci 1991, 74:3202-3208.
Browning R., Leite-Browning M.L., Lewis A.W., Randel R.D. Sire breed of calf influences peripartum endocrine profiles and postpartum anestrus in Brahman cows. Domest Anim Endocrinol 1996, 13:511-517.
López-Gatius F., Garbayo J.M., Santolaria P., Yániz J., Ayad A., de Sousa N.M., et al. Milk production correlates negatively with plasma levels of pregnancy-associated glycoprotein (PAG) during the early fetal period in high producing dairy cows with live fetuses. Domest Anim Endocrinol 2007, 32:29-42.
Serrano B., López-Gatius F., Santolaria P., Almería S., García-Ispierto I., Bech-Sabat G., et al. Factors affecting plasma pregnancy-associated glycoprotein 1 concentrations throughout gestation in high-producing dairy cows. Reprod Domest Anim 2009, 44:600-605.
Xie S., Low B.G., Nagel R.J., Beckers J.F., Roberts R.M. A novel glycoprotein of the aspartic proteinase gene family expressed in bovine placental trophectoderm. Biol Reprod 1994, 51:1145-1153.
Xie S.C., Low B.G., Nagel R.J., Kramer K.K., Anthony R.V., Zoli A.P., et al. Identification of the major pregnancy-specific antigens of cattle and sheep as inactive members of the aspartic proteinase family. Proc Natl Acad Sci U S A 1991, 88:10247-10251.
Humblot P., Camous S., Martal J., Charlery J., Jeanguyot N., Thibier M., et al. Diagnosis of pregnancy by radioimmunoassay of a pregnancy-specific protein in the plasma of dairy cows. Theriogenology 1988, 30:257-267.
Szenci O., Beckers J.F., Humblot P., Sulon J., Sasser G., Taverne M.A., et al. Comparison of ultrasonography, bovine pregnancy-specific protein B, and bovine pregnancy-associated glycoprotein 1 tests for pregnancy detection in dairy cows. Theriogenology 1998, 50:77-88.
Ayad A., Sousa N.M., Sulon J., Iguer-Ouada M., Beckers J.F. Comparison of five radioimmunoassay systems for PAG measurement: Ability to detect early pregnancy in cows. Reprod Domest Anim 2007, 42:433-440.
Patel O.V., Sulon J., Beckers J.F., Takahashi T., Hirako M., Sasaki N., et al. Plasma bovine pregnancy-associated glycoprotein concentrations throughout gestation in relationship to fetal number in the cow. Eur J Endocrinol 1997, 137:423-428.
Kornmatitsuk B., Dahl E., Ropstad E., Beckers J.E., Gustafsson H., Kindahl H. Endocrine profiles, haematology and pregnancy outcomes of late pregnant Holstein dairy heifers sired by bulls giving a high or low incidence of stillbirth. Acta Vet Scand 2004, 45:47-68.
Fisher S.J., Gimenez T., Henricks D.M. Immunosuppressive activity associated with early pregnancy in the bovine. Biol Reprod 1985, 32:894-906.
Hoeben D., Burvenich C., Massart-Leën A.M., Lenjou M., Nijs G., Van Bockstaele D., et al. In vitro effect of ketone bodies, glucocorticosteroids and bovine pregnancy-associated glycoprotein on cultures of bone marrow progenitor cells of cows and calves. Vet Immunol Immunopathol 1999, 68:229-240.
Hoeben D., Monfardini E., Opsomer G., Burvenich C., Dosogne H., De Kruif A., et al. Chemiluminescence of bovine polymorphonuclear leucocytes during the periparturient period and relation with metabolic markers and bovine pregnancy-associated glycoprotein. J Dairy Res 2000, 67:249-259.
Dosogne H., Burvenich C., Freeman A.E., Kehrli M.E., Detilleux J.C., Sulon J., et al. Pregnancy-associated glycoprotein and decreased polymorphonuclear leukocyte function in early post-partum dairy cows. Vet Immunol Immunopathol 1999, 67:47-54.
Kelemen K., Paldi A., Tinneberg H., Torok A., Szekeres-Bartho J. Early recognition of pregnancy by the maternal immune system. Am J Reprod Immunol 1998, 39:351-355.
Druckmann R., Druckmann M.A. Progesterone and the immunology of pregnancy. J Steroid Biochem Mol Biol 2005, 97:389-396.
Druckmann R. Review: Female sex hormones, autoimmune diseases and immune response. Gynecol Endocrinol 2001, 15(Suppl 6(Suppl 6)):69-76.
Ortega E., de Pablo M.A., Gaforio J.J., Gallego A.M., Alvarez C., Ruiz-Bravo A., et al. Modification of acquired immunity in BALB/c mice by aztreonam. Int J Antimicrob Agents 2000, 15:193-199.
Faas M.M., Moes H., van der Schaaf G., de Leij L.F., Heineman M.J. Total white blood cell counts and LPS-induced TNF alpha production by monocytes of pregnant, pseudopregnant and cyclic rats. J Reprod Immunol 2003, 59:39-52.
Franklin S.T., Newman M.C., Newman K.E., Meek K.I. Immune parameters of dry cows fed mannan oligosaccharide and subsequent transfer of immunity to calves. J Dairy Sci 2005, 88:766-775.
Serrano B., Almería S., García-Ispierto I., Yániz J.L., Abdelfattah-Hassan A., López-Gatius F. Peripheral white blood cell counts throughout pregnancy in non-aborting Neospora caninum-seronegative and seropositive high-producing dairy cows in a Holstein Friesian herd. Res Vet Sci 2011, 90:457-462.
Nutrient requirement of dairy cattle 2001, National Reseach Council, National Academies Press, Washington, D.C. 7th rev. ed.
Perényi Z.S., Szenci O., Drion P.V., Banga-Mboko H., Sousa N.M., El Amiri B., et al. Aspartic proteinase members secreted by the ruminant placenta: Specificity of three radioimmunoassay systems for the measurement of pregnancy-associated glycoproteins. Reprod Domest Anim 2002, 37:324-329.
Perényi Z.S., Szenci O., Sulon J., Drion P.V., Beckers J.F. Comparison of the ability of three radioimmunoassay to detect pregnancy-associated glycoproteins in bovine plasma. Reprod Domest Anim 2002, 37:100-104.
Vaitukaitis J., Robbins J.B., Nieschlag E., Ross G.T. A method for producing specific antisera with small doses of immunogen. J Clin Endocrinol Metab 1971, 33:988-991.
Atkinson G. Analysis of repeated measurements in physical therapy research. Phys Ther Sports 2001, 2:194-208.
Liu Y. Analyzing RM ANOVA related data using SPSS10. Meas Phys Educ Exerc Sci 2002, 6:43-60.
Ellis S.A., Sargent I.L., Charleston B., Bainbridge D.R. Regulation of MHC class I gene expression is at transcriptional and post-transcriptional level in bovine placenta. J Reprod Immunol 1998, 37:103-115.
Bainbridge D.R., Sargent I.L., Ellis S.A. Increased expression of major histocompatibility complex (MHC) class I transplantation antigens in bovine trophoblast cells before fusion with maternal cells. Reproduction 2001, 122:907-913.
Low B.G., Hansen P.J., Drost M., Gogolin-Ewens K.J. Expression of major histocompatibility complex antigens on the bovine placenta. J Reprod Fertil 1990, 90:235-243.
Davies C.J., Fisher P.J., Schlafer D.H. Temporal and regional regulation of major histocompatibility complex class I expression at the bovine uterine/placental interface. Placenta 2000, 21:194-202.
Mehrzad J., Duchateau L., Pyörälä S., Burvenich C. Blood and milk neutrophil chemiluminescence and viability in primiparous and pluriparous dairy cows during late pregnancy, around parturition and early lactation. J Dairy Sci 2002, 85:3268-3276.
Jones M.L., Allison R.W. Evaluation of the ruminant complete blood cell count. Vet Clin North Am Food Anim Prac 2007, 23:377-402.
Guidry A.J., Paape M.J., Pearson R.E. Effects of parturition and lactation on blood and milk cell concentrations, corticosteroids, and neutrophil phagocytosis in the cow. Am J Vet Res 1976, 37:1195-1200.
Da Silva F.M., Burvenich C., Leën A.M.M., Brossé L. Assessment of blood neutrophil oxidative burst activity in dairy cows during the period of parturition. Anim Sci 1998, 67:421-426.
Preisler M.T., Weber P.S., Tempelman R.J., Erskine R.J., Hunt H., Burton J.L. Glucocorticoid receptor down-regulation in neutrophils of periparturient cows. Am J Vet Res 2000, 61:14-19.
Preisler M.T., Weber P.S., Tempelman R.J., Erskine R.J., Hunt H., Burton J.L. Glucocorticoid receptor expression profiles in mononuclear leukocytes of periparturient Holstein cows. J Dairy Sci 2000, 83:38-47.
Oliveira L.J., McClellan S., Hansen P.J. Differentiation of the endometrial macrophage during pregnancy in the cow. PLoS ONE 2010, 5:e13213.