Article (Scientific journals)
Endometriose stade I et II: implications physiopathologiques, cliniques et therapeutiques
Nisolle, Michelle; Nervo, Patricia
2003In Journal de Gynécologie, Obstétrique et Biologie de la Reproduction, 32 (8, Pt 2), p. 11-4
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Abstract :
[en] Stage I and II endometriosis is defined by a r-AFS score respectively ranging from 1 to 5 and from 6 to 15. This mild, superficial endometriosis is a very common pathology occurring in infertile women. Nevertheless, these women with stage I/II endometriosis have usually few pelvic pain. This review summarizes the recent literature concerning new data on the pathogenesis of peritoneal endometriosis and its clinical management. Retrograde menstruation, peritoneal adhesion of shed endometrial tissue, and outgrowth of endometrial cells, glands and stroma, are essential elements in the pathogenesis of endometriosis according to Sampson's classic implantation theory. Nevertheless, exact pathophysiology of endometriosis remains unknown. Superficial endometriotic lesions observed by laparoscopy have to be treated. Surgical procedure is not difficult for stage I and II of endometriosis. Surgical procedure remains controversial. Carbon dioxide (CO2) Laser can be used for laparoscopic destruction of endometriosis. Newer procedures, such as SurgiTouch (Lumenis), are more effective in vaporization and decrease the risk thermal damage of contiguous structures. The monopolar scissors can also be used in order to excise the peritoneal endometriotic lesions. Medical treatment may be usefull if surgical treatment is not complete or if the pelvic cavity is hypervascularized. In these cases, Gonadotropin-Releasing Hormone agonists (Gn-RHa) are the most common and effective treatment.
Disciplines :
Reproductive medicine (gynecology, andrology, obstetrics)
Author, co-author :
Nisolle, Michelle ;  Centre Hospitalier Universitaire de Liège - CHU > Gynécologie-Obstétrique CHR
Nervo, Patricia ;  Centre Hospitalier Universitaire de Liège - CHU > Gynécologie-Obstétrique CHR
Language :
French
Title :
Endometriose stade I et II: implications physiopathologiques, cliniques et therapeutiques
Alternative titles :
[en] Physiopathology and Therapeutic Management of Stage I and Ii Endometriosis
Publication date :
December 2003
Journal title :
Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
ISSN :
0368-2315
eISSN :
1773-0430
Publisher :
Elsevier Masson, Paris, France
Volume :
32
Issue :
8, Pt 2
Pages :
S11-4
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 17 December 2011

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