Article (Scientific journals)
Diabete de type 2 et medicaments anti-inflammatoires: nouvelles perspectives therapeutiques?
Esser, Nathalie; Paquot, Nicolas; SCHEEN, André
2011In Revue Médicale Suisse, 7 (306), p. 1614-8, 1620
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Keywords :
Anti-Inflammatory Agents/therapeutic use; Diabetes Mellitus, Type 2/therapy; Humans; Metabolic Syndrome X/drug therapy
Abstract :
[en] It is now well accepted that a chronic, low-grade inflammation is observed in abdominal obesity, insulin resistance and type 2 diabetes mellitus, and that pro-inflammatory cytokines and oxidative stress play a role in the pathogenesis of type 2 diabetes. These new findings raise the question of whether antiinflammatory strategies may have a place in the prevention and treatment of type 2 diabetes. This review article describes the results obtained in studies on patients with metabolic syndrome or type 2 diabetes aiming to test the metabolic effect of anti-inflammatory (salicylates, antagonists of interleukine-1, antagonists of tumor necrosis factor-alpha) and anti-oxydants (succinobucol) drugs.
Disciplines :
Pharmacy, pharmacology & toxicology
Endocrinology, metabolism & nutrition
Author, co-author :
Esser, Nathalie  ;  Université de Liège - ULiège > GIGA-R : Virologie - Immunologie
Paquot, Nicolas ;  Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)
SCHEEN, André  ;  Centre Hospitalier Universitaire de Liège - CHU > Diabétologie,nutrition, maladies métaboliques
Language :
French
Title :
Diabete de type 2 et medicaments anti-inflammatoires: nouvelles perspectives therapeutiques?
Alternative titles :
[en] Type 2 diabetes and anti-inflammatory agents: new therapeutic prospects?
Publication date :
2011
Journal title :
Revue Médicale Suisse
ISSN :
1660-9379
Publisher :
Medecine et Hygiène, Switzerland
Volume :
7
Issue :
306
Pages :
1614-8, 1620
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 11 December 2011

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