Reference : How HTLV-1 may subvert miRNAs for persistence and transformation.
Scientific journals : Article
Human health sciences : Oncology
http://hdl.handle.net/2268/10430
How HTLV-1 may subvert miRNAs for persistence and transformation.
English
Bouzar, Amel [Université de Liège - ULiège > Chimie et bio-industries > Centre de Bio. Fond. - Section de Biologie cell. et moléc. >]
Willems, Luc mailto [Université de Liège - ULiège > > GIGA-Research >]
2008
Retrovirology
BioMed Central
5
101
Yes (verified by ORBi)
International
1742-4690
London
United Kingdom
[en] Apoptosis ; Cell Line, Transformed ; Cell Transformation, Neoplastic ; Human T-lymphotropic virus 1/physiology ; Humans ; MicroRNAs/metabolism
[en] Distinct mechanisms are used by viruses to interact with cellular miRNAs. The role of microRNAs in viral replication and persistence ranges from viral-encoded microRNAs to suppressors of RNA interference. Viruses can also exploit cellular miRNAs for influencing cellular metabolism to ensure efficient replication or latency. In particular, two recent studies provide examples of how HTLV-1 may co-opt or subvert cellular miRNAs for persistent replication and oncogenic purposes. The pathways modulated by these described miRNAs are critically involved in apoptosis, proliferation and innate immune response.
http://hdl.handle.net/2268/10430
also: http://hdl.handle.net/2268/18643
10.1186/1742-4690-5-101

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