[en] The pathogenesis of venous ulcers is complex. A critical bacterial colonization may play a harmfull role. The use of topical antibiotics is unwise, and that of antiseptics is still a matter of debate. Some authors contend that antiseptics mitigate wound healing through a toxic effect upon keratinocytes and fibroblasts. However, sound arguments support the paradoxical concept of beneficial cytotoxicity of antiseptics in the treatment of chronic venous ulcers.
Disciplines :
Dermatology
Author, co-author :
Henry, Frédérique ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Franchimont, Claudine ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Pierard, Gérald ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Language :
French
Title :
Ulcère veineux chronique et colonisation bactérienne critique. Quand antiseptique rime avec cytotoxicité bénéfique.
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