AIDS Serodiagnosis; Africa, Central; Ethnic Groups; HIV Antibodies; HIV Core Protein p24; HIV Infections; Serologic Tests; Immunology
Abstract :
[en] OBJECTIVE: Search for the rate of HIV-1 contamination among seronegative sexual partners of seropositive individuals. METHODS: Classical serological methods (EIA, WB) and PCR. SERIES: 36 heterosexual couples from central Africa, accounting for a total of 73 persons: 13/37 seropositive women, 23/36 seropositive men. All couples were serologically discordant, i.e. one partner was seropositive. CONCLUSIONS: In such a population, particularly at risk of HIV contamination, the rate of false negative serological diagnosis reached 70%.
Disciplines :
Immunology & infectious disease
Author, co-author :
Vaira, Dolorès ; Centre Hospitalier Universitaire de Liège - CHU > Immuno-hématologie
Sondag, Danièle ; Université de Liège - ULiège > Département des sciences de la santé publique > Immunohématologie - Transfusion
François-Gérard, C.
Doppagne, A.
Rentier, Bernard ; Université de Liège - ULiège > Département de Microbiologie > Virologie fondamentale et Immunologie
Language :
English
Title :
Diagnosis of HIV-1 in African couples : comparison of serology and PCR
Publication date :
1989
Event name :
Cinquième conférence internationale sur le SIDA : le défi scientifique et social= Fifth International Conference on AIDS : the Scientific and Social Challenge
Event place :
Montréal, Canada
Event date :
June 4-9, 1989
Audience :
International
Main work title :
Cinquième conférence internationale sur le SIDA : le défi scientifique et social
Main work alternative title :
[en] Fifth International Conference on AIDS : the Scientific and Social Challenge
Publisher :
Centre de Recherches pour le Développement International, Ottawa, Canada
