[en] In this chapter, we aimed at further characterizing the functional neuroanatomy of the human rapid eye movement (REM) sleep at the population level. We carried out a meta-analysis of a large dataset of positron emission tomography (PET) scans acquired during wakefulness, slow wave sleep and REM sleep, and focused especially on the brain areas in which the activity diminishes during REM sleep. Results show that quiescent regions are confined to the inferior and middle frontal cortex and to the inferior parietal lobule. Providing a plausible explanation for some of the features of dream reports, these findings may help in refining the concepts, which try to account for human cognition during REM sleep. In particular, we discuss the significance of these results to explain the alteration in executive processes, episodic memory retrieval and self representation during REM sleep dreaming as well as the incorporation of external stimuli into the dream narrative.
Disciplines :
Neurosciences & behavior
Author, co-author :
Maquet, Pierre ; Université de Liège - ULiège > Centre de recherches du cyclotron
Ruby, P.
Maudoux, Audrey ; Université de Liège - ULiège > Centre de recherches du cyclotron
Albouy, Geneviève ; Université de Liège - ULiège > Centre de recherches du cyclotron
Sterpenich, Virginie ; Université de Liège - ULiège > Centre de recherches du cyclotron
Dang Vu, Thien Thanh ; Université de Liège - ULiège > Centre de Recherches du Cyclotron - Département des sciences cliniques > Neurologie
Desseilles, Martin ; Université de Liège - ULiège > Département des sciences cliniques > Psychiatrie et psychologie médicale
Boly, Mélanie ; Université de Liège - ULiège > Centre de Recherches du Cyclotron > Neurologie
R. Adolphs Social cognition and the human brain Trends Cogn. Sci. 3 1999 469 479
R. Adolphs Neural systems for recognizing emotion Curr. Opin. Neurobiol. 12 2002 169 177
G. Aston-Jones, J. Rajkowski, and J. Cohen Locus coeruleus and regulation of behavioral flexibility and attention Prog. Brain Res. 126 2000 165 182
A. Baddeley The episodic buffer: a new component of working memory? Trends Cogn. Sci. 4 2000 417 423
A.R. Braun, T.J. Balkin, N.J. Wesenten, R.E. Carson, M. Varga, P. Baldwin, S. Selbie, G. Belenky, and P. Herscovitch Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study Brain 120 1997 1173 1197
A.R. Braun, T.J. Balkin, N.J. Wesensten, F. Gwadry, R.E. Carson, M. Varga, P. Baldwin, G. Belenky, and P. Herscovitch Dissociated pattern of activity in visual cortices and their projections during human rapid eye movement sleep Science 279 1998 91 95
E. Brunet, Y. Sarfati, M.C. Hardy-Bayle, and J. Decety A PET investigation of the attribution of intentions with a nonverbal task Neuroimage 11 2000 157 166
S.A. Burton, J.R. Harsh, and P. Badia Cognitive activity in sleep and responsiveness to external stimuli Sleep 11 1988 61 68
P. Carruthers, and P. Smith Theories of Theories of Mind 1996 Cambridge University Press Cambridge
T. Chaminade, and J. Decety Leader or follower? Involvement of the inferior parietal lobule in agency Neuroreport 28 2002 1975 1978
M. Corbetta, J.M. Kincade, J.M. Ollinger, M.P. McAvoy, and G.L. Shulman Voluntary orienting is dissociated from target detection in human posterior parietal cortex Nat. Neurosci. 3 2000 292 297
M. Corbetta, and G.L. Shulman Control of goal-directed and stimulus-driven attention in the brain Nat. Rev. Neurosci. 3 2002 201 215
C. Farrer, N. Franck, N. Georgieff, C.D. Frith, J. Decety, and M. Jeannerod Modulating the experience of agency: a positron emission tomography study Neuroimage 18 2003 324 333
P.C. Fletcher, F. Happe, U. Frith, S.C. Baker, R.J. Dolan, R.S. Frackowiak, and C.D. Frith Other minds in the brain: a functional imaging study of "theory of mind" in story comprehension Cognition 57 1995 109 128
M.J. Fosse, R. Fosse, J.A. Hobson, and R.J. Stickgold Dreaming and episodic memory: a functional dissociation? J. Cogn. Neurosci. 15 2003 1 9
D. Foulkes The Psychology of Sleep 1966 Charles Scribner's Sons New York
C.D. Frith Mind blindness and the brain in autism Neuron 20 2001 969 979
R.N. Henson, T. Shallice, and R.J. Dolan Right prefrontal cortex and episodic memory retrieval: a functional MRI test of the monitoring hypothesis Brain 122 Pt 7 1999 1367 1381
J.A. Hobson, E.F. Pace-Schott, R. Stickgold, and D. Kahn To dream or not to dream? Relevant data from new neuroimaging and electrophysiological studies Curr. Opin. Neurobiol. 8 1998 239 244
J. Hobson, E. Pace-Schott, and R. Stickgold Dreaming and the brain: toward a cognitive neuroscience of conscious states E. Pace-Schott M. Solms M. Blagrove S. Harnad Sleep and Dreaming 2003 Cambridge University Press Cambridge 1 50
E. Koechlin, C. Ody, and F. Kouneiher The architecture of cognitive control in the human prefrontal cortex Science 302 2003 1181 1185
B. Levine, S.E. Black, R. Cabeza, M. Sinden, A.R. McIntosh, J.P. Toth, E. Tulving, and D.T. Stuss Episodic memory and the self in a case of isolated retrograde amnesia Brain 121 Pt 10 1998 1951 1973
R. Lydic, H.A. Baghdoyan, L. Hibbard, E.V. Bonyak, M.R. DeJoseph, and R.A. Hawkins Regional brain glucose metabolism is altered during rapid eye movement sleep in the cat: a preliminary study J. Comp. Neurol. 304 1991 517 529
P. Maquet Functional neuroimaging of normal human sleep by positron emission tomography J. Sleep Res. 9 2000 207 231
P. Maquet, and G. Franck REM sleep and amygdala Mol. Psychiatr. 2 1997 195 196
P. Maquet, S. Laureys, P. Peigneux, S. Fuchs, C. Petiau, C. Phillips, J. Aerts, G. Del Fiore, C. Degueldre, T. Meulemans, A. Luxen, G. Franck, M. Van Der Linden, C. Smith, and A. Cleeremans Experience-dependent changes in cerebral activation during human REM sleep Nat. Neurosci. 3 2000 831 836
P. Maquet, J. Péters, J. Aerts, G. Delfiore, C. Degueldre, A. Luxen, and G. Franck Functional neuroanatomy of human rapid-eye-movement sleep and dreaming Nature 383 1996 163 166
J.H. Morrison, and S.L. Foote Noradrenergic and serotoninergic innervation of cortical, thalamic, and tectal visual structures in Old and New World monkeys J. Comp. Neurol. 243 1986 117 138
P. Peigneux, S. Laureys, S. Fuchs, F. Collette, F. Perrin, J. Reggers, C. Phillips, C. Degueldre, G. Del Fiore, J. Aerts, A. Luxen, and P. Maquet Are spatial memories strengthened in the human hippocampus during slow wave sleep? Neuron 44 2004 535 545
K. Phan, T. Wager, S. Taylor, and I. Liberzon Functional neuroanatomy of emotion: A meta-analysis of emotion activation studies in PET and fMRI Neuroimage 16 2002 331 348
A. Rechtschaffen, and A.A. Kales A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects 1968 US Department of Health Education and Welfare Bethesda
P. Ruby, and J. Decety Effect of subjective perspective taking during simulation of action: a PET investigation of agency Nat. Neurosci. 4 2001 546 550
P. Ruby, and J. Decety What you believe versus what you think they believe: A neuroimaging study of conceptual perspective-taking Eur. J. Neurosci. 17 11 2003 2475 2480
P. Ruby, and J. Decety How would you feel versus how do you think she would feel? A neuroimaging study of perspective-taking with social emotions J. Cogn. Neurosci. 16 2004 988 999
M.D. Rugg, L.J. Otten, and R.N. Henson The neural basis of episodic memory: evidence from functional neuroimaging Phil. Trans. R. Soc. Lond. B Biol. Sci. 357 2002 1097 1110
S. Schwartz, and P. Maquet Sleep imaging and the neuro-psychological assessment of dreams Trends Cogn. Sci. 1 2002 23 30
M. Solms The Neuropsychology of Dreams 1997 Lawrence Erlbaum Associates Inc. Mahwah
M. Steriade, and R.W. McCarley Brainstem Control of Wakefulness and Sleep 1990 Plenum Press New York
E. Tulving Episodic memory: from mind to brain Rev. Neurol. (Paris) 160 2004 S9 S23
