Profil

Pierre Nicolas

GIGA I3 - Translational gastroenterology

Département des sciences cliniques > Hépato-gastroentérologie

See author's contact details
ORCID
0000-0002-8324-0434
Main Referenced Co-authors
Louis, Edouard  (29)
Meuwis, Marie-Alice  (27)
Baiwir, Dominique  (18)
Mazzucchelli, Gabriel  (18)
Huynh-Thu, Vân Anh  (15)
Main Referenced Keywords
Animals (9); Crohn's disease (8); Mice (7); ER stress (5); Male (4);
Main Referenced Unit & Research Centers
Laboratoire de gastro-entérologie translationnelle (1)
Main Referenced Disciplines
Gastroenterology & hepatology (28)
Biochemistry, biophysics & molecular biology (12)

Publications (total 40)

The most downloaded
444 downloads
Pierre, N., Salée, C., Vieujean, S., Bequet, E., Merli, A.-M., Siegmund, B., Meuwis, M.-A., & Louis, E. (2021). Review article: distinctions between ileal and colonic Crohn's disease: from physiology to pathology. Alimentary Pharmacology and Therapeutics, 54 (6), 779-791. doi:10.1111/apt.16536 https://hdl.handle.net/2268/266889

The most cited

83 citations (Scopus®)

Pierre, N., Deldicque, L., Barbe, C., Naslain, D., Cani, P. D., & Francaux, M. (2013). Toll-like receptor 4 knockout mice are protected against endoplasmic reticulum stress induced by a high-fat diet. PLoS ONE, 8 (5), 65061. doi:10.1371/journal.pone.0065061 https://hdl.handle.net/2268/237017

The most significant

Pierre, N., Vieujean, S., Peyrin-Biroulet, L., Meuwis, M.-A., & Louis, E. (2023). Defining biological remission in Crohn's disease: interest, challenges and future directions. Journal of Crohn's and Colitis. doi:10.1093/ecco-jcc/jjad086
Peer Reviewed verified by ORBi

Pierre, N., Huynh-Thu, V. A., Marichal, T., Allez, M., Bouhnik, Y., Laharie, D., Bourreille, A., Colombel, J.-F., Meuwis, M.-A., Louis, E., & GETAID (Groupe d’Etude Thérapeutique des Affections Inflammatoires du tube Digestif). (2022). Distinct blood protein profiles associated with the risk of short-term and mid/long-term clinical relapse in patients with Crohn's disease stopping infliximab: when the remission state hides different types of residual disease activity. Gut, 2022-327321. doi:10.1136/gutjnl-2022-327321
Peer Reviewed verified by ORBi

Pierre, N., Salée, C., Vieujean, S., Bequet, E., Merli, A.-M., Siegmund, B., Meuwis, M.-A., & Louis, E. (2021). Review article: distinctions between ileal and colonic Crohn's disease: from physiology to pathology. Alimentary Pharmacology and Therapeutics, 54 (6), 779-791. doi:10.1111/apt.16536
Peer reviewed

Pierre, N., Baiwir, D., Huynh-Thu, V. A., Mazzucchelli, G., Smargiasso, N., De Pauw, E., Bouhnik, Y., Laharie, D., Colombel, J.-F., Meuwis, M.-A., & Louis, E. (2021). Discovery of biomarker candidates associated with the risk of short-term and mid/long-term relapse after infliximab withdrawal in Crohn's patients: a proteomics-based study. Gut. doi:10.1136/gutjnl-2020-322100
Peer Reviewed verified by ORBi

Pierre, N., Salee, C., MASSOT, C., BLETARD, N., Mazzucchelli, G., Smargiasso, N., Morsa, D., Baiwir, D., De Pauw, E., REENAERS, C., VAN KEMSEKE, C., LOLY, J.-P., Delvenne, P., Meuwis, M.-A., & Louis, E. (2019). Proteomics highlights common and distinct pathophysiological processes associated with ileal and colonic ulcers in Crohn's disease. Journal of Crohn's & colitis. doi:10.1093/ecco-jcc/jjz130
Peer reviewed


Articles accepted in reviewed journal

Pierre, N., Vieujean, S., Peyrin-Biroulet, L., Meuwis, M.-A., & Louis, E. (2023). Defining biological remission in Crohn's disease: interest, challenges and future directions. Journal of Crohn's and Colitis. doi:10.1093/ecco-jcc/jjad086
Peer Reviewed verified by ORBi

VIEUJEAN, S., GILLARD, R., Delanaye, P., Seidel, L., Bequet, E., Salée, C., Meuwis, M.-A., Massot, C., Pierre, N., Meunier, P., Cavalier, E., & Louis, E. (2023). Matrix gla protein, a potential marker of tissue remodelling and physiological ageing of the gut in crohn’s disease. Scandinavian Journal of Gastroenterology, 1-8. doi:10.1080/00365521.2023.2286913
Peer Reviewed verified by ORBi

Pierre, N., Huynh-Thu, V. A., Marichal, T., Allez, M., Bouhnik, Y., Laharie, D., Bourreille, A., Colombel, J.-F., Meuwis, M.-A., Louis, E., & GETAID (Groupe d’Etude Thérapeutique des Affections Inflammatoires du tube Digestif). (2022). Distinct blood protein profiles associated with the risk of short-term and mid/long-term clinical relapse in patients with Crohn's disease stopping infliximab: when the remission state hides different types of residual disease activity. Gut, 2022-327321. doi:10.1136/gutjnl-2022-327321
Peer Reviewed verified by ORBi

VIEUJEAN, S., Hu, S., Bequet, E., SALEE, C., MASSOT, C., BLETARD, N., Pierre, N., Quesada Calvo, F., Baiwir, D., Mazzucchelli, G., De Pauw, E., COIMBRA MARQUES, C., DELVENNE, P., Rieder, F., LOUIS, E., & MEUWIS, M.-A. (October 2021). Potential Role of Epithelial Endoplasmic Reticulum Stress and Anterior Gradient Protein 2 Homolog in Crohn’s Disease Fibrosis. Journal of Crohn's and Colitis, 15 (10), 1737-1750. doi:10.1093/ecco-jcc/jjab061
Peer Reviewed verified by ORBi

Pierre, N., Salée, C., Vieujean, S., Bequet, E., Merli, A.-M., Siegmund, B., Meuwis, M.-A., & Louis, E. (2021). Review article: distinctions between ileal and colonic Crohn's disease: from physiology to pathology. Alimentary Pharmacology and Therapeutics, 54 (6), 779-791. doi:10.1111/apt.16536
Peer reviewed

Pierre, N., Baiwir, D., Huynh-Thu, V. A., Mazzucchelli, G., Smargiasso, N., De Pauw, E., Bouhnik, Y., Laharie, D., Colombel, J.-F., Meuwis, M.-A., & Louis, E. (2021). Discovery of biomarker candidates associated with the risk of short-term and mid/long-term relapse after infliximab withdrawal in Crohn's patients: a proteomics-based study. Gut. doi:10.1136/gutjnl-2020-322100
Peer Reviewed verified by ORBi

Appriou, Z., Nay, K., Pierre, N., Saligaut, D., Lefeuvre-Orfila, L., Martin, B., Cavey, T., Ropert, M., Loreal, O., Rannou-Bekono, F., & Derbre, F. (2019). Skeletal muscle ceramides do not contribute to physical inactivity-induced insulin resistance. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. doi:10.1139/apnm-2018-0850
Peer reviewed

Pierre, N., Salee, C., MASSOT, C., BLETARD, N., Mazzucchelli, G., Smargiasso, N., Morsa, D., Baiwir, D., De Pauw, E., REENAERS, C., VAN KEMSEKE, C., LOLY, J.-P., Delvenne, P., Meuwis, M.-A., & Louis, E. (2019). Proteomics highlights common and distinct pathophysiological processes associated with ileal and colonic ulcers in Crohn's disease. Journal of Crohn's & colitis. doi:10.1093/ecco-jcc/jjz130
Peer reviewed

Cavey, T.* , Pierre, N.* , Nay, K., Allain, C., Ropert, M., Loreal, O., & Derbre, F. (2017). Simulated microgravity decreases circulating iron in rats: role of inflammation-induced hepcidin upregulation. Experimental Physiology, 102 (3), 291-298. doi:10.1113/EP086188
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Rodriguez, J., Pierre, N., Naslain, D., Bontemps, F., Ferreira, D., Priem, F., Deldicque, L., & Francaux, M. (2017). Urolithin B, a newly identified regulator of skeletal muscle mass. Journal of Cachexia, Sarcopenia and Muscle, 8 (4), 583-597. doi:10.1002/jcsm.12190
Peer Reviewed verified by ORBi

Pierre, N., Appriou, Z., Gratas-Delamarche, A., & Derbre, F. (2016). From physical inactivity to immobilization: Dissecting the role of oxidative stress in skeletal muscle insulin resistance and atrophy. Free Radical Biology and Medicine, 98, 197-207. doi:10.1016/j.freeradbiomed.2015.12.028
Peer Reviewed verified by ORBi

Pierre, N., Fernandez-Verdejo, R., Regnier, P., Vanmechelen, S., Demeulder, B., & Francaux, M. (2016). IRE1alpha and TRB3 do not contribute to the disruption of proximal insulin signaling caused by palmitate in C2C12 myotubes. Cell Biology International, 40 (1), 91-9. doi:10.1002/cbin.10542
Peer Reviewed verified by ORBi

Rodriguez, J., Fernandez-Verdejo, R., Pierre, N., Priem, F., & Francaux, M. (2016). Endurance Training Attenuates Catabolic Signals Induced by TNF-alpha in Muscle of Mice. Medicine and Science in Sports and Exercise, 48 (2), 227-34. doi:10.1249/MSS.0000000000000756
Peer Reviewed verified by ORBi

Rodriguez, J., Gilson, H., Jamart, C., Naslain, D., Pierre, N., Deldicque, L., & Francaux, M. (2015). Pomegranate and green tea extracts protect against ER stress induced by a high-fat diet in skeletal muscle of mice. European Journal of Nutrition, 54 (3), 377-89. doi:10.1007/s00394-014-0717-9
Peer Reviewed verified by ORBi

Chalil, S., Pierre, N., Bakker, A. D., Manders, R. J., Pletsers, A., Francaux, M., Klein-Nulend, J., Jaspers, R. T., & Deldicque, L. (2015). Aging related ER stress is not responsible for anabolic resistance in mouse skeletal muscle. Biochemical and Biophysical Research Communications, 468 (4), 702-7. doi:10.1016/j.bbrc.2015.11.019
Peer reviewed

Pierre, N., Barbe, C., Gilson, H., Deldicque, L., Raymackers, J.-M., & Francaux, M. (2014). Activation of ER stress by hydrogen peroxide in C2C12 myotubes. Biochemical and Biophysical Research Communications, 450 (1), 459-63. doi:10.1016/j.bbrc.2014.05.143
Peer reviewed

Pierre, N., Deldicque, L., Barbe, C., Naslain, D., Cani, P. D., & Francaux, M. (2013). Toll-like receptor 4 knockout mice are protected against endoplasmic reticulum stress induced by a high-fat diet. PLoS ONE, 8 (5), 65061. doi:10.1371/journal.pone.0065061
Peer Reviewed verified by ORBi

Zbinden-Foncea, H., Deldicque, L., Pierre, N., Francaux, M., & Raymackers, J.-M. (2012). TLR2 and TLR4 activation induces p38 MAPK-dependent phosphorylation of S6 kinase 1 in C2C12 myotubes. Cell Biology International, 36 (12), 1107-13. doi:10.1042/CBI20120081
Peer Reviewed verified by ORBi

Articles accepted in conference proceedings

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., Laharie, D., Satsangi, J., Colombel, J. F., Hertervig, E., Meuwis, M.-A., & Louis, E. (30 January 2023). Distinct biological profiles associated with the risk of short-term relapse and mid/long-term relapse in Crohn’s disease patients stopping infliximab. Journal of Crohn's and Colitis, 17 (Supplement_1), 3-i6. doi:10.1093/ecco-jcc/jjac190.0002
Peer Reviewed verified by ORBi

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., David Laharie, Jack Satsangi, Jean-Frédéric Colombel, Erik Hertervig, Meuwis, M.-A., & Louis, E. (2023). Distinct biological profiles associated with the risk of short-term relapse and mid/long-term relapse in Crohn’s disease patients stopping infliximab. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Pierre, N., Huynh-Thu, V. A., Allez, M., Bouhnik, Y., Laharie, D., Bourreille, A., Colombel, J. F., Meuwis, M.-A., & Louis, E. (2021). Blood proteins related to immunoregulation or cellular junctions reveal distinct biological profiles associated with the risk of short-term versus mid/long-term relapse in Crohn’s Disease patients stopping infliximab. Journal of Crohn's and Colitis. doi:10.1093/ecco-jcc/jjab075.011
Peer Reviewed verified by ORBi

Pierre, N., Huynh-Thu, V. A., Matthieu Allez, Yoram Bouhnik, David Laharie, Arnaud Bourreille, Jean-Frédéric Colombel, Meuwis, M.-A., & Louis, E. (2021). Blood proteins linked to immune tolerance, inflammation and cellular junctions reveal a succession of pathophysiological events preceding the relapse in Crohn’s disease patients stopping infliximab. Acta Gastro-Enterologica Belgica.
Peer reviewed

Pierre, N., REENAERS, C., VAN KEMSEKE, C., LOLY, J.-P., Mazzucchelli, G., Smargiasso, N., Baiwir, D., Morsa, D., De Pauw, E., MEUWIS, M.-A., & Louis, E. (2018). Proteomic analysis highlights divergences and convergences between ileal and colonic pathological processes involved in Crohn’s ulcers. Journal of Crohn's and Colitis. doi:10.1093/ecco-jcc/jjx180.184
Peer Reviewed verified by ORBi

Oral presentations in conferences with scientific selection committee

Pierre, N., Huynh-Thu, V. A., Baiwir, D., VIEUJEAN, S., Bequet, E., Reenaers, C., Van Kemseke, C., Salée, C., Massot, C., Fleron, M., Mazzucchelli, G., Trzpiot, L., Eppe, G., De Pauw, E., Louis, E., & Meuwis, M.-A. (2024). Distinct blood protein profiles associated with ileal and colonic ulcers in Crohn’s disease [Paper presentation]. Belgian Week of Gastroenterology 2024.
Peer reviewed

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., David Laharie, Jack Satsangi, Jean-Frédéric Colombel, Erik Hertervig, Meuwis, M.-A., & Louis, E. (2023). Distinct biological profiles associated with the risk of short-term relapse and mid/long-term relapse in Crohn’s disease patients stopping infliximab [Paper presentation]. European Crohn's and Colitis Organisation (ECCO) congress.
Peer reviewed

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., David, L., Jack, S., Jean-Frédéric, C., Erik, H., Meuwis, M.-A., & Louis, E. (2023). Distinct biological profiles associated with the risk of short-term relapse and mid/long-term relapse in Crohn’s disease patients stopping infliximab [Paper presentation]. Belgian Week of Gastroenterology 2023.
Peer reviewed

Pierre, N., Baiwir, D., Mazzucchelli, G., Fleron, M., PAULISSEN, G., Huynh-Thu, V. A., De Pauw, E., Eppe, G., LOUIS, E., & MEUWIS, M.-A. (04 May 2022). Improving precision of selected reaction monitoring with a two steps internal standard normalisation [Paper presentation]. 5th Symposium of the Belgian Proteomics Association.
Peer reviewed

VIEUJEAN, S., DELANAYE, P., SEIDEL, L., CAVALIER, E., Pierre, N., & LOUIS, E. (2022). Matrix Gla Protein, a potential marker of tissue remodelling and physiological ageing of the gut in Crohn's disease [Paper presentation]. Belgian Week of Gastroenterology 2022.
Peer reviewed

Vieujean, S., Hu, S., Bequet, E., SALEE, C., MASSOT, C., BLETARD, N., Pierre, N., Quesada Calvo, F., Baiwir, D., Mazzucchelli, G., De Pauw, E., COIMBRA MARQUES, C., DELVENNE, P., LOUIS, E., & MEUWIS, M.-A. (03 March 2021). Potential Role of Epithelial Protein Disulphide Isomerases in Crohn’s Disease Fibrosis [Paper presentation]. Belgian Week of Gastroenterology_33rd edition.
Peer reviewed

Pierre, N., Huynh-Thu, V. A., Matthieu, A., Yoram, B., David, L., Arnaud, B., Jean-Frédéric, C., Meuwis, M.-A., & Louis, E. (2021). Blood proteins linked to immune tolerance, inflammation and cellular junctions reveal a succession of pathophysiological events preceding the relapse in Crohn’s disease patients stopping infliximab [Paper presentation]. 33rd Belgian Week of Gastroenterology 2021, Belgium.
Peer reviewed

Pierre, N., Huynh-Thu, V. A., Matthieu Allez, Yoram Bouhnik, David Laharie, Arnaud Bourreille, Jean-Frédéric Colombel, Meuwis, M.-A., & Louis, E. (2021). Blood proteins related to immunoregulation or cellular junctions reveal distinct biological profiles associated with the risk of short-term versus mid/long-term relapse in Crohn’s Disease patients stopping infliximab [Paper presentation]. European Crohn's and Colitis Organisation (ECCO) congress 2021.
Peer reviewed

Posters presentations in conferences with scientific selection committee

Pierre, N., Huynh-Thu, V. A., Baiwir, D., VIEUJEAN, S., Bequet, E., Reenaers, C., Van Kemseke, C., Salée, C., Massot, C., Fleron, M., Mazzucchelli, G., Trzpiot, L., Eppe, G., De Pauw, E., Louis, E., & Meuwis, M.-A. (02 February 2024). Distinct blood protein profiles associated with ileal and colonic ulcers in Crohn’s disease [Poster presentation]. Belgian Week of Gastroenterology 2024, Antwerp, Belgium.
Peer reviewed

Pierre, N., Huynh-Thu, V. A., Baiwir, D., VIEUJEAN, S., Bequet, E., Reenaers, C., Van Kemseke, C., Salée, C., Massot, C., Fleron, M., Mazzucchelli, G., Trzpiot, L., Eppe, G., De Pauw, E., Louis, E., & Meuwis, M.-A. (2024). Distinct blood protein profiles associated with ileal and colonic ulcers in Crohn’s disease [Poster presentation]. European Crohn's and Colitis Organisation 2024, Stockholm, Sweden.
Peer reviewed

Pierre, N., Baiwir, D., Mazzucchelli, G., Fleron, M., Paulissen, G., Huynh-Thu, V. A., De Pauw, E., Eppe, G., Louis, E., & Meuwis, M.-A. (2022). Improving precision of selected reaction monitoring with a two steps internal standard normalisation [Poster presentation]. Next-Generation Protein Analysis and Detection (4th edition), Ghent, Belgium.
Editorial reviewed

VIEUJEAN, S., DELANAYE, P., SEIDEL, L., CAVALIER, E., Pierre, N., & LOUIS, E. (01 January 2022). P168 Matrix Gla protein, a potential marker of tissue remodelling and physiological ageing of the gut in Crohn’s Disease [Poster presentation]. European Crohn's and Colitis Organisation 2022. doi:10.1093/ecco-jcc/jjab232.296
Peer reviewed

VIEUJEAN, S., Hu, S., Bequet, E., SALEE, C., MASSOT, C., BLETARD, N., Pierre, N., Quesada Calvo, F., Baiwir, D., Mazzucchelli, G., De Pauw, E., COIMBRA MARQUES, C., Delvenne, P., LOUIS, E., & MEUWIS, M.-A. (July 2021). Potential Role of Epithelial Protein Disulphide Isomerases in Crohn’s Disease Fibrosis [Poster presentation]. 16th Congress of European Crohn's and Colitis Organisation - Inflammatory Bowel Diseases 2021 Virtual.
Peer reviewed

Vieujean, S., Hu, S., Bequet, E., Salee, C., Massot, C., BLETARD, N., Pierre, N., QUESADA CALVO, F., Baiwir, D., Mazzucchelli, G., De Pauw, E., Delvenne, P., Louis, E., & Meuwis, M.-A. (05 March 2020). Increased Endoplasmic Reticulum stress specific chaperones characterise CD fibrosis epithelium tissues and participates to in vitro induction of intestinal fibroblasts differentiation [Poster presentation]. Belgian Week of Gastroenterology, Antwerpen, Belgium.
Peer reviewed

Vieujean, S., Hu, S., Bequet, E., Salee, C., Massot, C., BLETARD, N., Pierre, N., Quesada Calvo, F., Baiwir, D., Mazzucchelli, G., De Pauw, E., Delvenne, P., LOUIS, E., & Meuwis, M.-A. (14 February 2020). Increased Endoplasmic Reticulum stress specific chaperones characterise CD fibrosis epithelium tissues and participate to in vitro induction of intestinal fibroblasts differentiation [Poster presentation]. European Crohn's and Colitis Organisation (ECCO), Vienna, Austria.
Peer reviewed

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