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Dubois Laurence

GIGA Molecular & Comput. Biol. - Gene Expression & Cancer

Département des sciences de la vie > GIGA

Génétique et biologie moléculaires animales

See author's contact details
Main Referenced Co-authors
Bruyr, Jonathan  (9)
Dequiedt, Franck  (9)
Lucarelli, Eva  (9)
Ongena, Loïc  (9)
Galvan, Bartimée  (7)
Main Referenced Keywords
Alternative splicing, sarcoma, FET (1); Alternative splicing, sarcoma, FET, (1); Animals (1); Bone Neoplasms/genetics (1); Bone Neoplasms/metabolism (1);
Main Referenced Unit & Research Centers
GIGA-MBD - GIGA Molecular Biology of Disease, Laboratory of Gene Expression and Cancer (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (9)

Publications (total 9)

The most downloaded
49 downloads
Lucarelli, E.* , Ongena, L.* , Dubois, L., Galvan, B., Bruyr, J., & Dequiedt, F.*. (17 July 2023). FET fusion oncoproteins hijack the LASR complex to rewire alternative splicing in sarcomas [Poster presentation]. 5th International Caparica Conference in Splicing (SPLICING 2023), Caparica, Portugal. https://hdl.handle.net/2268/306073

The most cited

1 citations (OpenAlex)

Galvan, B., Ongena, L., Bruyr, J., Fettweis, G., Lucarelli, E., Lavergne, A., Mariavelle, E., O'Grady, T. M., Hassoun, Z. E. O., Claes, M., Dubois, L., Lee, K. A. W., Kruys, V., Gueydan, C., Durand, J., Hervouet, E., Geyer, F. H., Banito, A., Imle, R., ... Dequiedt, F. (16 July 2025). Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma. Nature Communications, 16 (1), 6537. doi:10.1038/s41467-025-61725-x https://hdl.handle.net/2268/335247

Galvan, B., Ongena, L., Bruyr, J., Fettweis, G., Lucarelli, E., Lavergne, A., Mariavelle, E., O'Grady, T. M., Hassoun, Z. E. O., Claes, M., Dubois, L., Lee, K. A. W., Kruys, V., Gueydan, C., Durand, J., Hervouet, E., Geyer, F. H., Banito, A., Imle, R., ... Dequiedt, F. (16 July 2025). Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma. Nature Communications, 16 (1), 6537. doi:10.1038/s41467-025-61725-x
Peer Reviewed verified by ORBi

Dubois, L., Ongena, L., Lucarelli, E., Galvan, B., Salek, K., Bruyr, J., & Dequiedt, F. (29 January 2025). Characterization of a novel role for oncogenic transcription factors in mRNA decay [Poster presentation]. Séminaire Télévie 2025.

Lucarelli, E., Ongena, L., Dubois, L., Galvan, B., Bruyr, J., & Dequiedt, F. (17 October 2024). FET fusion oncoproteins rewire alternative splicing patterns to drive sarcomagenesis [Poster presentation]. EMBO/EMBL Symposium: The complex life of RNA, Heidelberg, Germany.

Lucarelli, E., Ongena, L., Dubois, L., Galvan, B., Bruyr, J., & Dequiedt, F. (30 May 2024). FET fusion oncoproteins rewire alternative splicing patterns to drive sarcomagenesis [Poster presentation]. The Interuniversity Ph.D. Student Day, Louvain-la-Neuve, Belgium.

Dubois, L., Ongena, L., Lucarelli, E., Bruyr, J., Galvan, B., & Dequiedt, F. (2024). Characterization of a novel role for FET oncogenic fusions in the regulation of mRNA stability [Poster presentation]. Séminaire Télévie 2024.

Dubois, L., Ongena, L., Lucarelli, E., Galvan, B., Bruyr, J., & Dequiedt, F. (2024). Characterization of a novel role for FET oncogenic fusions in the regulation of mRNA stability [Poster presentation]. EMBO | EMBL Symposium: The complex life of RNA.

Lucarelli, E.* , Ongena, L.* , Dubois, L., Galvan, B., Bruyr, J., & Dequiedt, F.*. (17 July 2023). FET fusion oncoproteins hijack the LASR complex to rewire alternative splicing in sarcomas [Poster presentation]. 5th International Caparica Conference in Splicing (SPLICING 2023), Caparica, Portugal.
* These authors have contributed equally to this work.

Ongena, L., Lucarelli, E., Dubois, L., Bruyr, J., & Dequiedt, F. (July 2023). FET fusion transcription factors regulate alternative splicing to promote oncogenesis [Poster presentation]. International Caparica Conference in Splicing, Caparica, Portugal.

Ongena, L., Lucarelli, E., Dubois, L., Bruyr, J., & Dequiedt, F. (24 April 2023). Quantitative and qualitative regulation of gene expression by FET oncogenic fusions [Poster presentation]. Post-transcriptional Gene Regulation: From mechanisms to RNA chemistry and therapeutics, Paris, France.

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