Profil

Njock Makon-Sébastien

GIGA I3 - Pneumology

See author's contact details
ORCID
0000-0001-8137-1978
Main Referenced Co-authors
Guiot, Julien  (18)
Louis, Renaud  (16)
Struman, Ingrid  (14)
Henket, Monique  (13)
Moermans, Catherine  (10)
Main Referenced Keywords
Humans (10); Biomarkers (4); exosomes (4); inflammation (4); microRNA (4);
Main Referenced Unit & Research Centers
GIGA-I3 - Giga-Infection, Immunity and Inflammation - ULiège [BE] (2)
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (1)
GIGA-CME - GIGA Cancer-Cellular and Molecular Epigenetics - ULiège [BE] (1)
GIGA-LAM - GIGA Cancer-Molecular Angiogenesis Laboratory - ULiège [BE] (1)
GIGA‐R - Giga‐Research - ULiège [BE] (1)
Main Referenced Disciplines
Cardiovascular & respiratory systems (22)
Biochemistry, biophysics & molecular biology (8)
Oncology (5)
Genetics & genetic processes (2)
Endocrinology, metabolism & nutrition (1)

Publications (total 40)

The most downloaded
228 downloads
Moermans, C., Graff, S., Gerday, S., Schleich, F., Guiot, J., Njock, M.-S., & Louis, R. (2022). LES PROBIOTIQUES DANS LE TRAITEMENT DE L’ASTHME. Revue Médicale de Liège, 77 (5-6), 285 - 288. https://hdl.handle.net/2268/297896

The most cited

203 citations (Scopus®)

Njock, M.-S., Cheng, H. S., Dang, L. T., Nazari-Jahantigh, M., Lau, A. C., Boudreau, E., Roufaiel, M., Cybulsky, M. I., Schober, A., & Fish, J. E. (14 May 2015). Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAs. Blood, 125 (20), 3202-12. doi:10.1182/blood-2014-11-611046 https://hdl.handle.net/2268/217788

Welsh, J. A., Goberdhan, D. C. I., O'Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., Falcon-Perez, J. M., Fu, Q.-L., Hill, A. F., Lenassi, M., Lim, S. K., Mahoney, M. G., Mohanty, S., Möller, A., Nieuwland, R., ... Witwer, K. W. (February 2024). Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of Extracellular Vesicles, 13 (2), 12404. doi:10.1002/jev2.12404
Peer Reviewed verified by ORBi

Nix, C., Sulejman, S., Cobraiville, G., Njock, M.-S., Paulissen, G., de Seny, D., & Fillet, M. (2024). Development of complementary analytical methods to characterize extracellular vesicles [Paper presentation]. CIRM Day, Liege, Belgium.

Guiot, J., & Njock, M.-S. (01 September 2023). Editorial: Progressive fibrosing interstitial lung disease: from bench to bedside. Frontiers in Medicine, 10. doi:10.3389/fmed.2023.1277909
Peer Reviewed verified by ORBi

Guiot, J., Henket, M., Remacle, C., Cambier, M., Struman, I., Winandy, M.-L., Moermans, C., Louis, E., Malaise, M., Ribbens, C., Louis, R., & Njock, M.-S. (15 April 2023). Systematic review of overlapping microRNA patterns in COVID-19 and idiopathic pulmonary fibrosis. Respiratory Research, 24 (1), 112. doi:10.1186/s12931-023-02413-6
Peer Reviewed verified by ORBi

Guiot, J., Henket, M., Ernst, M., Seidel, L., WINANDY, M.-L., DENIS, A., Frix, A.-N., GESTER, F., THYS, M., GILTAY, L., Garah, O., Njock, M.-S., CANIVET, P., Meunier, P., Corhay, J.-L., Regnier, C., Malaise, O., Malaise, M., & Louis, R. (09 March 2023). Airflow obstruction as a marker of adverse prognosis in rheumatoid arthritis. Frontiers in Medicine, 10. doi:10.3389/fmed.2023.1063012
Peer Reviewed verified by ORBi

Beauvois, A.* , Gazon, H.* , Chauhan, P. S., Jamakhani, M., Jacques, J.-R., Thiry, M., Dejardin, E., Di Valentin, E., Twizere, J.-C., Péloponèse, J.-M., Njock, M.-S., Yasunaga, J.-I., Matsuoka, M., Hamaïdia, M.* , & Willems, L.*. (2023). The helicase-like transcription factor redirects the autophagic flux and restricts human T-cell leukemia virus type 1 infection. Proceedings of the National Academy of Sciences of the United States of America, 120 (31), 2216127120. doi:10.1073/pnas.2216127120
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

NJOCK, M.-S.* , O'Grady, T.* , Nivelles, O., Lion, M., Jacques, S., Cambier, M., Herkenne, S., Muller, F., Christian, A., REMACLE, C., GUIOT, J., Rahmouni, S., Dequiedt, F.* , & Struman, I.*. (June 2022). Endothelial extracellular vesicles promote tumour growth by tumour-associated macrophage reprogramming. Journal of Extracellular Vesicles, 11 (6), 12228. doi:10.1002/jev2.12228
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

GUIOT, J., HENKET, M., Frix, A.-N., GESTER, F., THYS, M., GILTAY, L., DESIR, C., MOERMANS, C., NJOCK, M.-S., MEUNIER, P., CORHAY, J.-L., & LOUIS, R. (11 April 2022). Combined obstructive airflow limitation associated with interstitial lung diseases (O-ILD): the bad phenotype ? Respiratory Research, 23 (1), 89. doi:10.1186/s12931-022-02006-9
Peer Reviewed verified by ORBi

O'Grady, T.* , NJOCK, M.-S.* , Lion, M., Bruyr, J., Mariavelle, E., Galvan, B., Boeckx, A., Struman, I.* , & Dequiedt, F.*. (24 March 2022). Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels. BMC Biology, 20 (1), 72. doi:10.1186/s12915-022-01277-4
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Veitch, S.* , Njock, M.-S.* , Chandy, M.* , Siraj, M. A., Chi, L., Mak, H., Yu, K., Rathnakumar, K., Perez-Romero, C. A., Chen, Z., Alibhai, F. J., Gustafson, D., Raju, S., Wu, R., Zarrin Khat, D., Wang, Y., Caballero, A., Meagher, P., Lau, E., ... Fish, J. E. (February 2022). MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes. Cardiovascular Diabetology, 21 (1), 31. doi:10.1186/s12933-022-01458-z
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Moermans, C., Graff, S., Gerday, S., Schleich, F., Guiot, J., Njock, M.-S., & Louis, R. (2022). LES PROBIOTIQUES DANS LE TRAITEMENT DE L’ASTHME. Revue Médicale de Liège, 77 (5-6), 285 - 288.
Editorial Reviewed verified by ORBi

Cambier, M., Henket, M., Frix, A.-N., Gofflot, S., THYS, M., Tomasetti, S., Peired, A., Struman, I., Rousseau, A.-F., Misset, B., Darcis, G., Moutschen, M., Louis, R., Njock, M.-S., Cavalier, E., & Guiot, J. (2022). Increased KL-6 levels in moderate to severe COVID-19 infection. PLoS ONE, 17 (11), 0273107. doi:10.1371/journal.pone.0273107
Peer Reviewed verified by ORBi

Moermans, C., Damas, K., Guiot, J., NJOCK, M.-S., Corhay, J.-L., Henket, M., Schleich, F., & Louis, R. (April 2021). Sputum IL-25, IL-33 and TSLP, IL-23 and IL-36 in airway obstructive diseases. Reduced levels of IL-36 in eosinophilic phenotype. Cytokine, 140, 155421. doi:10.1016/j.cyto.2021.155421
Peer Reviewed verified by ORBi

GUIOT, J., NJOCK, M.-S., ANDRE, B., GESTER, F., HENKET, M., DE SENY, D., MOERMANS, C., MALAISE, M., & LOUIS, R. (2021). Serum IGFBP-2 in systemic sclerosis as a prognostic factor of lung dysfunction. Scientific Reports, 11 (1), 10882. doi:10.1038/s41598-021-90333-0
Peer Reviewed verified by ORBi

Guiot, J., HENKET, M., NJOCK, M.-S., MOERMANS, C., Struman, I., Corhay, J.-L., & Louis, R. (2021). La fibrose pulmonaire : des biomarqueurs à de nouveaux horizons thérapeutiques. Revue Médicale de Liège, 76 (3), 166-172.
Peer reviewed

Parzibut, G., Henket, M., Moermans, C., Struman, I., Louis, E., Malaise, M., Louis, R., Misset, B., NJOCK, M.-S.* , & Guiot, J.*. (2021). A Blood Exosomal miRNA Signature in Acute Respiratory Distress Syndrome. Frontiers in Molecular Biosciences, 8, 640042. doi:10.3389/fmolb.2021.640042
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Parzibut, G., GUIOT, J., Misset, B., MALAISE, M., LOUIS, R., LOUIS, E., HENKET, M., MOERMANS, C., & NJOCK, M.-S. (September 2020). Alteration of Plasma Exosome Content in Acute Respiratory Distress Syndrome: a miRNA signature associated to lung fibrosing process [Poster presentation]. ERS International Congress 2020. doi:10.1183/13993003.congress-2020.3828

GUIOT, J., Cambier, M., Boeckx, A., HENKET, M., Nivelles, O., GESTER, F., LOUIS, E., MALAISE, M., Dequiedt, F., LOUIS, R., Struman, I.* , & NJOCK, M.-S.*. (05 August 2020). Macrophage-derived exosomes attenuate fibrosis in airway epithelial cells through delivery of antifibrotic miR-142-3p. Thorax, 75 (10), 870-881. doi:10.1136/thoraxjnl-2019-214077
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Poulet, C., NJOCK, M.-S., MOERMANS, C., LOUIS, E., LOUIS, R., MALAISE, M., & GUIOT, J. (01 May 2020). Exosomal Long Non-Coding RNAs in Lung Diseases. International Journal of Molecular Sciences, 21 (10), 3580. doi:10.3390/ijms21103580
Peer Reviewed verified by ORBi

Guiot, J., HENKET, M., André, B., Herzog, M., Hardat, N., NJOCK, M.-S., MOERMANS, C., Malaise, M., & Louis, R. (2020). A new nucleosomic-based model to identify and diagnose SSc-ILD. Clinical Epigenetics, 12 (1), 124. doi:10.1186/s13148-020-00915-4
Peer Reviewed verified by ORBi

GUIOT, J., Struman, I., Louis, E., Louis, R., Malaise, M., & Njock, M.-S. (2019). Exosomal miRNAs in Lung Diseases: From Biologic Function to Therapeutic Targets. Journal of Clinical Medicine, 8 (9). doi:10.3390/jcm8091345
Peer Reviewed verified by ORBi

Njock, M.-S., O'Grady, T., Nivelles, O., Dequiedt, F., & Struman, I. (13 September 2018). Tumor microenvironment affects the composition of endothelial-derived exosomes: impact in tumor progression [Paper presentation]. GIGA-CANCER DAY, Liège, Belgium.

Njock, M.-S., GUIOT, J., HENKET, M., Nivelles, O., LOUIS, R., & Struman, I. (May 2018). Sputum exosomes - promising biomarkers for idiopathic pulmonary fibrosis [Poster presentation]. International Society for Extracellular Vesicles, Barcelone, Spain. doi:10.1080/20013078.2018.1461450

O'Grady, T., Njock, M.-S., Lion, M., Struman, I., & Dequiedt, F. (May 2018). Integrating long and short sequencing data for a global overview of the endothelial extracellular vesicle RNA landscape [Poster presentation]. International Society for Extracellular Vesicles, Barcelone, Spain.

Njock, M.-S., GUIOT, J., HENKET, M., Nivelles, O., Thiry, M., Dequiedt, F., Corhay, J.-L., Louis, R., & Struman, I. (2018). Sputum exosomes: promising biomarkers for idiopathic pulmonary fibrosis. Thorax. doi:10.1136/thoraxjnl-2018-211897
Peer Reviewed verified by ORBi

Chandy, M., Njock, M.-S., Veitch, S., Bugyei-Twum, A., Cheng, H., Momen, A., Connelly, K., Fish, J., & Husain, M. (14 November 2017). Circulating Extracellular Vesicles From Mouse and Rat Models of Diabetes Reveal Specific Microrna Signatures as Biomarkers of Diabetic Cardiomyopathy [Poster presentation]. American Heart Association's 2017 Scientific Sessions and Resuscitation Science Symposium.

Fish, J. E., Cantu Gutierrez, M., Dang, L. T., Khyzha, N., Chen, Z., Veitch, S., Cheng, H. S., Khor, M., Antounians, L., Njock, M.-S., Boudreau, E., Herman, A. M., Rhyner, A. M., Ruiz, O. E., Eisenhoffer, G. T., Medina-Rivera, A., Wilson, M. D., & Wythe, J. D. (01 July 2017). Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network. Development, 144 (13), 2428-2444. doi:10.1242/dev.146050
Peer Reviewed verified by ORBi

Njock, M.-S., O'Grady, T., Dequiedt, F., & Struman, I. (2017). Tumour microenvironment affects the composition of endothelial cell-derived extracellular vesicles: impact in tumour progression. Journal of Extracellular Vesicles. doi:10.1080/20013078.2017.1310414

Njock, M.-S., Chandy, M., Veitch, S. C., Gustafson, D., Chen, Z., Connelly, K., Husain, M., & Fish, J. E. (2017). Diabetes affects extracellular vesicle content and function. Journal of Extracellular Vesicles.

Njock, M.-S., & Fish, J. E. (March 2017). Endothelial miRNAs as Cellular Messengers in Cardiometabolic Diseases. Trends in Endocrinology and Metabolism, 28 (3), 237-246. doi:10.1016/j.tem.2016.11.009
Peer Reviewed verified by ORBi

Barker, K. R., Lu, Z., Kim, H., Zheng, Y., Chen, J., Conroy, A. L., Hawkes, M., Cheng, H. S., Njock, M.-S., Fish, J. E., Harlan, J. M., Lopez, J. A., Liles, W. C., & Kain, K. C. (02 February 2017). miR-155 Modifies Inflammation, Endothelial Activation and Blood-Brain Barrier Dysfunction in Cerebral Malaria. Molecular Medicine, 23, 24-33. doi:10.2119/molmed.2016.00139
Peer reviewed

Njock, M.-S., O'Grady, T., Nivelles, O., Dequiedt, F., & Struman, I. (2017). Tumor microenvironment affects the composition of endothelial-derived extracellular vesicles: Impact in tumor progression [Poster presentation]. International Society for Extracellular Vesicles Annual Meeting.

Njock, M.-S., Cheng, H. S., Dang, L. T., Nazari-Jahantigh, M., Lau, A. C., Boudreau, E., Roufaiel, M., Cybulsky, M. I., Schober, A., & Fish, J. E. (14 May 2015). Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAs. Blood, 125 (20), 3202-12. doi:10.1182/blood-2014-11-611046
Peer Reviewed verified by ORBi

Cheng, H. S., Njock, M.-S., Khyzha, N., Dang, L. T., & Fish, J. E. (14 December 2014). Noncoding RNAs regulate NF-kappaB signaling to modulate blood vessel inflammation. Frontiers in Genetics, 5, 422. doi:10.3389/fgene.2014.00422
Peer Reviewed verified by ORBi

Njock, M.-S., Fouchier, F., Seree, E., Villard Pierre, H., Landrier Jean, F., Pechere, L., Barra, Y., & Champion, S. (07 May 2014). Lycopene modulates THP1 and Caco2 cells inflammatory state through transcriptional and nontranscriptional processes. Mediators of Inflammation, 2014, 507272. doi:10.1155/2014/507272
Peer Reviewed verified by ORBi

Njock, M.-S. (2014). Secreted miRNAs regulate vascular inflammation [Paper presentation]. Canadian Vascular Network Meeting, Vancouver, Canada.

Lacroix, R., Plawinski, L., Robert, S., Doeuvre, L., Sabatier, F., Martinez de Lizarrondo, S., Mezzapesa, A., Anfosso, F., Leroyer, A. S., Poullin, P., Jourde, N., Njock, M.-S., Boulanger, C. M., Angles-Cano, E., & Dignat-George, F. (December 2012). Leukocyte- and endothelial-derived microparticles: a circulating source for fibrinolysis. Haematologica, 97 (12), 1864-72. doi:10.3324/haematol.2012.066167
Peer Reviewed verified by ORBi

Lacroix, R., Plawinski, L., Doeuvre, L., Sabatier, F., Martinez de Lizarrondo, S., Mezzapesa, A., Anfosso, F., Leroyer, A. S., Poullin, P., Jourde, N., Njock, M.-S., Vivien, D., Boulanger, C. M., Angles-Cano, E., & Dignat-George, F. (October 2012). C0082 Circulating leukocyte- and endothelial-derived microparticles support a fibrinolytic activity. Thrombosis Research, 130, 115–S116. doi:10.1016/j.thromres.2012.08.042
Peer Reviewed verified by ORBi

Leroyer, A. S., Anfosso, F., Lacroix, R., Sabatier, F., Simoncini, S., Njock, M.-S., Jourde, J., Brunet, P., Camoin-Jau, L., Sampol, J., & Dignat-George, F. (September 2010). Endothelial-derived microparticles: Biological conveyors at the crossroad of inflammation, thrombosis and angiogenesis. Thrombosis and Haemostasis, 104 (3), 456-63. doi:10.1160/TH10-02-0111
Peer Reviewed verified by ORBi

Simoncini, S.* , Njock, M.-S.* , Robert, S., Camoin-Jau, L., Sampol, J., Harle, J.-R., Nguyen, C., Dignat-George, F., & Anfosso, F. (23 April 2009). TRAIL/Apo2L mediates the release of procoagulant endothelial microparticles induced by thrombin in vitro: a potential mechanism linking inflammation and coagulation. Circulation Research, 104 (8), 943-51. doi:10.1161/CIRCRESAHA.108.183285
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Contact ORBi