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Tits Alexandra

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Main Referenced Co-authors
Ruffoni, Davide  (24)
Drion, Pierre  (15)
Kaux, Jean-François  (12)
Van Lenthe, G. Harry (11)
Blouin, Stéphane (9)
Main Referenced Keywords
Enthesis (5); Bone-tendon interface (4); Nanoindentation (4); Finite Element Modeling (3); Nano indentation (3);
Main Referenced Unit & Research Centers
FOCUS - Freshwater and OCeanic science Unit of reSearch - ULiège (2)
Mechanics of Biological and Bio-Inspired Materials Lab - MBBM (1)
Mechanics of Biological and Bioinspired Materials lab (1)
Mechanics of Biological and Biosinpired Materials lab (1)
MolSys - Molecular Systems - ULiège (1)
Main Referenced Disciplines
Engineering, computing & technology: Multidisciplinary, general & others (23)
Orthopedics, rehabilitation & sports medicine (3)
Life sciences: Multidisciplinary, general & others (3)
Zoology (2)
Materials science & engineering (1)

Publications (total 26)

The most downloaded
341 downloads
Tits, A. (2023). Attaching soft to hard: A multimodal correlative investigation of the tendon-bone interface [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/298023 https://hdl.handle.net/2268/298023

The most cited

32 citations (OpenAlex)

Tits, A., & Ruffoni, D. (2021). Joining soft tissues to bone: Insights from modeling and simulations. Bone Reports. doi:10.1016/j.bonr.2020.100742 https://hdl.handle.net/2268/255703

Sensini, A., Raimondi, L., Malerba, A., Silva, C. P., Zucchelli, A., Tits, A., Ruffoni, D., Blouin, S., Hartmann, M. A., van Griensven, M., & Moroni, L. (17 April 2025). Understanding the structure and mechanics of the sheep calcaneal enthesis: a relevant animal model to design scaffolds for tissue engineering applications. Biomaterials advances, 175, 214320. doi:10.1016/j.bioadv.2025.214320
Peer Reviewed verified by ORBi

Malerba, A., Tits, A., Volders, T., Vena, P., & Ruffoni, D. (July 2024). DO STIFFNESS GRADIENTS PLAY A ROLE IN THE PROTECTION OF THE TENDON-TO-BONE INTERFACE? A COMPUTATIONAL STUDY [Poster presentation]. 29th Congress of the European Society of Biomechanics, Edinburgh, United Kingdom.

Tits, A., Blouin, S., Rummler, M., Kaux, J.-F., Drion, P., van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (August 2023). Structural and functional heterogeneity of mineralized fibrocartilage at the Achilles tendon-bone insertion. Acta Biomaterialia, 166, 409 - 418. doi:10.1016/j.actbio.2023.04.018
Peer Reviewed verified by ORBi

Müller, L., Tits, A., Weinkamer, R., Drion, P., Dall'Ara, E., Van Lenthe, G. H., & Ruffoni, D. (10 July 2023). Changes in subchondral bone microstructure and shape with age in tibial knee [Paper presentation]. 28th Congress of the European Society of Biomechanics, Maastricht, Netherlands.
Editorial reviewed

Lew, A. J., Stifler, C. A., Tits, A., Schmidt, C. A., Scholl, A., Cantamessa, A., Müller, L., Delaunois, Y., Compère, P., Ruffoni, D., Buehler, M. J., & Gilbert, P. U. P. A. (July 2023). A Molecular-Scale Understanding of Misorientation Toughening in Corals and Seashells. Advanced Materials, 35 (28), 2300373. doi:10.1002/adma.202300373
Peer Reviewed verified by ORBi

Tits, A., Blouin, S., Rummler, M., Kaux, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (31 March 2023). Bone-fibrocartilage crosstalk and osteocyte lacuno-canalicular network at the tendon-bone insertion [Paper presentation]. European Society of Biomechanics Conference, Maastricht, Netherlands.
Editorial reviewed

Delaunois, Y., Tits, A., Grossman, Q., Smeets, S., Malherbe, C., Eppe, G., van Lenthe, G. H., Ruffoni, D.* , & Compère, P.*. (2023). Design Strategies of the Mantis Shrimp Spike: How the Crustacean Cuticle Became a Remarkable Biological Harpoon? Natural Sciences. doi:10.22541/au.167199666.61851387/v1
Peer reviewed
* These authors have contributed equally to this work.

Lew, A. J., Stifler, C. A., Cantamessa, A., Tits, A., Ruffoni, D., Gilbert, P. U. P. A., & Buehler, M. J. (2023). Deep learning virtual indenter maps nanoscale hardness rapidly and non-destructively, revealing mechanism and enhancing bioinspired design. Matter, 6 (6), 1975-1991. doi:10.1016/j.matt.2023.03.031
Peer Reviewed verified by ORBi

Tits, A. (2023). Attaching soft to hard: A multimodal correlative investigation of the tendon-bone interface [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/298023

Malerba, A., Tits, A., Volders, T., Vena, P., & Ruffoni, D. (2023). A COMPUTATIONAL INVESTIGATION OF THE TENDON-TO-BONE INSERTION: THE ROLE OF TISSUE ANISOTROPY [Paper presentation]. 28th Congress of the European Society of Biomechanics, Maastricht, Netherlands.

Delaunois, Y., Smeets, S., Tits, A., Ruffoni, D., & Compère, P. (22 September 2022). The spiky exoskeleton of the spearing mantis shrimp; comparative study of 3 puncturing bio-tools [Paper presentation]. Benelux Congress of Zoology, Kortrijk, Belgium.

Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (31 March 2022). Biomechanics and mechanobiology of mineralized fibrocartilage at the tendon-bone attachment [Paper presentation]. European Society of Biomechanics Conference, Porto, Portugal.
Editorial reviewed

Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (21 March 2022). Combining high-resolution imaging techniques to reveal the structure and function of fibrocartilage at the tendon-bone insertion [Paper presentation]. International Workshop on Quantitative Musculoskeletal Imaging, in combination with 9th International Symposium on Ultrasonic Characterization of Bone, Noordwijck, Netherlands.
Editorial reviewed

Müller, L., Tits, A., Plougonven, E., Drion, P., Dall'Ara, E., Léonard, A., Van Lenthe, H., & Ruffoni, D. (2022). Architecture of the trabecular bone between the metaphyseal and subchondral parts in the knee joint [Paper presentation]. 20th National Day of Biomedical Engineering, Bruxelles, Belgium.

Müller, L., Tits, A., Plougonven, E., Drion, P., Dall'Ara, E., Van Lenthe, G. H., & Ruffoni, D. (2022). Differences between subchondral and trabecular bone microporosities beneath the bone-cartilage interface at the knee joint [Poster presentation]. 15th Congress of the International Society of Bone Morphometry, Odense, Denmark.
Editorial reviewed

Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (02 November 2021). Biomechanical and biological aspects of mineralized fibrocartilage at the tendon-bone interface: a multi-modal analysis [Paper presentation]. Bones and Teeth Gordon Research Conference, Ventura, United States.
Editorial reviewed

Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (23 October 2021). A multimodal investigation of mineralized fibrocartilage at the tendon-bone insertion [Paper presentation]. Annual retreat of the Ludwig Boltzmann Institute of Osteology.

Tits, A., Plougonven, E., Blouin, S., Hartmann, M. A., Kaux, J.-F., Drion, P., Fernandez, J., van Lenthe, G. H., & Ruffoni, D. (August 2021). Local anisotropy in mineralized fibrocartilage and subchondral bone beneath the tendon-bone interface. Scientific Reports, 11, 16534. doi:10.1038/s41598-021-95917-4
Peer Reviewed verified by ORBi

Tits, A., Blouin, S., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M., & Ruffoni, D. (13 July 2021). Microstructural anisotropy and material gradients in mineralized fibrocartilage at the tendon-bone insertion [Paper presentation]. 26th Congress of the European Society of Biomechanics, Milan (Online), Italy.

Tits, A., & Ruffoni, D. (2021). Joining soft tissues to bone: Insights from modeling and simulations. Bone Reports. doi:10.1016/j.bonr.2020.100742
Peer Reviewed verified by ORBi

Tits, A., Varga, P., Volders, T., Kaux, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (October 2020). Local adaptation of bone micro-structure and canal network to tendon insertion investigated by image-based micro-FE simulations. Bone Reports, 13, 100392. doi:10.1016/j.bonr.2020.100393
Peer Reviewed verified by ORBi

Tits, A., Varga, P., KAUX, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (24 June 2020). Soft-to-hard biological interfaces: microstructural and micromechanical investigation of the tendon-bone attachment [Paper presentation]. European Calcified Tissue Society Digital Masterclass.

Tits, A., KAUX, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (17 December 2019). Microstructural and micromechanical investigation of the tendon-bone attachment [Paper presentation]. 8th International Conference on Mechanics of Biomaterials and Tissues (ICMOBT), Waikoloa Beach, Hawaii, United States.

Delaunois, Y., Malherbe, C., Tits, A., Ruffoni, D., & Compère, P. (10 September 2019). Reinforcement and adaptation of the mantis shrimp spike: how crustacean cuticle became a perfect harpoon? [Paper presentation]. 15th International Symposium on Biomineralization, Munich, Germany.

Tits, A., KAUX, J.-F., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (July 2019). Structural and mechanical analysis of calcaneus bone at the Achilles tendon insertion site [Paper presentation]. 25th World Congress of the European Society of Biomechanics – ESB 2019, Vienne, Austria.

Tits, A. (2018). Structural and mechanical analysis of Achilles tendon insertion into calcaneus [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/245186

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