Penoy, N.* , Delma, K. L.* , Homkar, N., Karim Sakira, A., Egrek, S., Sacheli, R., Sacre, P.-Y., Grignard, B., Hayette, M.-P., Somé, T. I., Semdé, R., Evrard, B., & Piel, G. (15 February 2024). Development and optimization of a one step process for the production and sterilization of liposomes using supercritical CO2. International Journal of Pharmaceutics, 651, 123769. doi:10.1016/j.ijpharm.2024.123769 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |
Penoy, N., Delma, K. L.* , Berger, M., Evrard, B., & Piel, G. (2024). Supercritical fluid methods for liposome production and sterilization. In Antimisiaris Sophia G., Liposomes in drug delivery : what, where, how and when to deliver. Elsevier. Peer reviewed * These authors have contributed equally to this work. |
Penoy, N., Delma, K. L., Grignard, B., Evrard, B., & Piel, G. (23 May 2023). The use of supercritical CO2 to develop liposomes encapsulating active pharmaceutical ingredients for pulmonary administration [Poster presentation]. 19th European Meeting on Supercritical Fluids, Budapest, Hungary. |
Dinh, T. N., Bya, L.-A., Lechanteur, A., Penoy, N., Evrard, B., & Piel, G. (28 April 2023). LIPOSOME FOR THE TREATMENT OF COPD PRODUCED BY SUPERCRITICAL CARBON DIOXIDE-BASED TECHNOLOGIES [Paper presentation]. 21st Forum of Pharmaceutical Sciences, Blankenberge, Belgium. |
Gauthy, C., Penoy, N., Evrard, B., Malgrange, B., & Piel, G. (28 April 2023). Development of optimized liposomes for sustained-release transtympanic administration [Paper presentation]. 21st Forum of Pharmaceutical Sciences, Blankenberge, Belgium. |
Penoy, N., Delma, K. L., EGREK, S., Grignard, B., Sacheli, R., Sacre, P.-Y., Hayette, M.-P., Evrard, B., & Piel, G. (27 April 2023). Supercritical CO2 to produce and sterilize liposomes: How to find supercritical parameters with the QbD strategy [Paper presentation]. BSPS - 21th Forum of Pharmaceutical Sciences, Blankerberge, Belgium. |
Dinh, T. N., Bya, L.-A., Lechanteur, A., Penoy, N., Evrard, B., & Piel, G. (01 February 2023). Liposome containing ciclesonide with/without indacaterol produced by supercritical carbon dioxide-based technologies [Poster presentation]. CIRM Day, Liège, Belgium. |
Dinh, T. N., Bya, L.-A., Lechanteur, A., Penoy, N., Evrard, B., & Piel, G. (01 February 2023). Liposome containing ciclesonide with/without indacaterol produced by supercritical carbon dioxide-based technologies [Poster presentation]. CIRM Day, Liège, Belgium. |
Gauthy, C., Penoy, N., Evrard, B., Malgrange, B., & Piel, G. (01 February 2023). Development of a sustained-release form of dexamethasone for the local treatment of sensorineural hearing loss [Poster presentation]. CIRM Day, Liège, Belgium. |
Delma, K. L., Penoy, N., Sakira, A. K., EGREK, S., Sacheli, R., Grignard, B., Hayette, M.-P., Issa Somé, T., Evrard, B., Semdé, R., & Piel, G. (11 January 2023). Use of supercritical CO2 for the sterilization of liposomes: Study of the influence of sterilization conditions on the chemical and physical stability of phospholipids and liposomes. European Journal of Pharmaceutics and Biopharmaceutics, 183, 112 - 118. doi:10.1016/j.ejpb.2023.01.002 Peer Reviewed verified by ORBi |
Dinh, T. N., Bya, L.-A., Lechanteur, A., Penoy, N., Evrard, B., & Piel, G. (2023). LIPOSOME FOR THE TREATMENT OF COPD PRODUCED BY SUPERCRITICAL CARBON DIOXIDE-BASED TECHNOLOGIES [Paper presentation]. 21st Forum of Pharmaceutical Sciences, Blankenberge, Belgium. |
Penoy, N. (2022). Développement et optimisation d'une méthode de production transposable à l'échelle industrielle de nanoparticules par la technologie des fluides supercritiques [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/305044 |
Penoy, N., Delma, K. L., Tonakpon, H. A., Grignard, B., Evrard, B., & Piel, G. (October 2022). An innovative one step green supercritical CO2 process for the production of liposomes co-encapsulating both a hydrophobic and a hydrophilic compound for pulmonary administration. International Journal of Pharmaceutics, 627, 122212. doi:10.1016/j.ijpharm.2022.122212 Peer Reviewed verified by ORBi |
Delma, K. L., Delma, K. L., Penoy, N., Grignard, B., Semdé, R., Evrard, B., & Piel, G. (29 March 2022). Effects of supercritical carbon dioxide under conditions potentially conducive to sterilization on chemical stability of phospholipids and physicochemical characteristics of a liposome formulation [Poster presentation]. 13th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Rotterdam, Netherlands. Peer reviewed |
Delma, K. L., Delma, K. L., Penoy, N., Grignard, B., Semdé, R., Evrard, B., & Piel, G. (02 February 2022). Applicability of supercritical carbon dioxide sterilization to liposomes: effects of potential conditions on phospholipids and liposomes stability [Paper presentation]. CIRM day 2022, Liège, Belgium. |
Delma, K. L., Penoy, N., Grignard, B., Semdé, R., Evrard, B., & Piel, G. (January 2022). Effects of supercritical carbon dioxide under conditions potentially conducive to sterilization on physicochemical characteristics of a liposome formulation containing apigenin. Journal of Supercritical Fluids, 179, 105418. doi:10.1016/j.supflu.2021.105418 Peer Reviewed verified by ORBi |
Penoy, N., Grignard, B., Evrard, B., & Piel, G. (06 April 2021). Double Encapsulation in liposomes for pulmonary administration produced by an innovative supercritical process [Paper presentation]. Controlled Release Society BeNeLux&France Early Career Scientists Meeting (online). Peer reviewed |
Penoy, N., Grignard, B., Evrard, B., & Piel, G. (04 March 2021). A supercritical PGSS method to encapsulate budesonide in liposome: comparison with the classical tFH method [Paper presentation]. CRS Local Chapters Meeting Germany and BeNeLux & France (online). Peer reviewed |
Penoy, N., Koch, N., Grignard, B., Evrard, B., & Piel, G. (March 2021). The quality by design strategy to prepare different liposomes formulations by a new supercritical fluid method [Poster presentation]. APGI Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology. Peer reviewed |
Penoy, N., Grignard, B., Evrard, B., & Piel, G. (2021). A supercritical fluid technology for liposome production and comparison with the film hydration method. International Journal of Pharmaceutics, 592, 120093. doi:10.1016/j.ijpharm.2020.120093 Peer Reviewed verified by ORBi |
Penoy, N., Avohou, T. H., Lebrun, P., Evrard, B., & Piel, G. (11 December 2019). A quality by design approach for liposomes production by innovative method using supercritical fluids: which parameters use to obtain good physicochemical characteristics? [Paper presentation]. Second CIRM Scientific Day, Liège, Belgium. |
Penoy, N., Avohou, T. H., Lebrun, P., Evrard, B., & Piel, G. (11 December 2019). A quality by design approach for liposomes production by innovative method using supercritical fluids: which parameters use to obtain good physicochemical characteristics? [Paper presentation]. Second CIRM Scientific Day, Liège, Belgium. |
Penoy, N., Bigazzi, W., Avohou, T. H., Lebrun, P., Evrard, B., & Piel, G. (20 May 2019). LIPOSOME PRODUCTION BY INNOVATIVE METHOD USING SUPERCRITICAL FLUIDS [Paper presentation]. 20th Forum of Pharmaceutical Sciences, Bruxelles, Belgium. |
Emonts, P., Penoy, N., Rocks, N., Piel, G., Fillet, M., Hubert, P., Ziemons, E., & Evrard, B. (19 January 2019). Update of the progresses and development prospects of the FEDER project Phare [Paper presentation]. CIRM seminars, Liege, Belgium. |
Bigazzi, W., Penoy, N., Evrard, B., & Piel, G. (2019). Supercritical fluid methods: an alternative to conventional methods to prepare liposomes. Chemical Engineering Journal. doi:10.1016/j.cej.2019.123106 Peer Reviewed verified by ORBi |
Penoy, N., Bigazzi, W., Piel, G., & Evrard, B. (19 December 2018). Liposome production by innovative method using supercritical fluids [Paper presentation]. 1st CIRM Scientific Day, liege, Belgium. |