Profil

Hego Alexandre

GIGA Platform Imaging & Flow cytometry

Département des sciences biomédicales et précliniques

See author's contact details
Main Referenced Co-authors
Oury, Cécile  (42)
Lancellotti, Patrizio  (23)
Lecut, Christelle  (22)
Delierneux, Céline  (20)
Servais, Laurence  (14)
Main Referenced Keywords
inflammation (3); Humans (2); Lung (2); mitochondria (2); Molecular Biology (2);
Main Referenced Unit & Research Centers
Giga-Cancer - ULiège [BE] (3)
d‐BRU - Dental Biomaterials Research Unit - ULiège [BE] (3)
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (2)
GIGA Cardiovascular Sciences-Cardiology - ULiège [BE] (1)
Main Referenced Disciplines
Cardiovascular & respiratory systems (16)
Hematology (10)
Biochemistry, biophysics & molecular biology (10)
Oncology (4)
Life sciences: Multidisciplinary, general & others (3)

Publications (total 50)

The most downloaded
178 downloads
LANCELLOTTI, P., NCHIMI LONGANG, A., Delierneux, C., Hego, A., Gosset, C., Gothot, A., TSHIBANDA, L., & Oury, C. (2015). Biological Effects of Cardiac Magnetic Resonance on Human Blood Cells. Circulation: Cardiovascular Imaging, 8 (9). doi:10.1161/CIRCIMAGING.115.003697 https://hdl.handle.net/2268/186924

The most cited

65 citations (Scopus®)

JOSSE, C., Bouznad, N., Geurts, P., Irrthum, A., Huynh-Thu, V. A., Servais, L., Hego, A., Delvenne, P., Bours, V., & Oury, C. (2014). Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis. American Journal of Physiology - Gastrointestinal and Liver Physiology, 306, 229-43. doi:10.1152/ajpgi.00484.2012 https://hdl.handle.net/2268/164117

Legrand, C., Vanneste, D., Hego, A., Sabatel, C., Mollers, K., Schyns, J., Maréchal, P., Abinet, J., Tytgat, A., Liégeois, M., Polese, B., Meunier, M., Radermecker, C., Fievez, L., Bureau, F., & Marichal, T. (2024). Lung Interstitial Macrophages Can Present Soluble Antigens and Induce Foxp3+ Regulatory T Cells. American Journal of Respiratory Cell and Molecular Biology. doi:10.1165/rcmb.2023-0254OC
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Layios, N., Gosset, C., Maes, N., Delierneux, C., Hego, A., Huart, J., LECUT, C., DAMAS, P., Oury, C., & Gothot, A. (2023). Prospective flow cytometry analysis of leucocyte subsets in critically ill patients who develop sepsis: a pilot study. Infection. doi:10.1007/s15010-023-01983-3
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Janssen, P.* , Tosi, I.* , Hego, A., Maréchal, P., Marichal, T.* , & Radermecker, C.*. (13 July 2022). Neutrophil Extracellular Traps Are Found in Bronchoalveolar Lavage Fluids of Horses With Severe Asthma and Correlate With Asthma Severity. Frontiers in Immunology, 13. doi:10.3389/fimmu.2022.921077
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* These authors have contributed equally to this work.

Radermecker, C., Hego, A., Vanwinge, C., & Marichal, T. (2022). Methods to Detect Neutrophil Extracellular Traps in Asthma. In Methods in Molecular Biology. Springer Nature. doi:10.1007/978-1-0716-2364-0_20
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Anania, S., Boumahd, Y., Peiffer, R., Thiry, M., Hego, A., Maloujahmoum, N., Agirman, F., Bellahcene, A., & Peulen, O. (June 2021). Myoferlin, a promising therapeutic target in PDAC, is located in mitochondria-associated membranes [Poster presentation]. 27TH CONGRESS OF THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH.

Jacques, S., Arjomand, A., Perée, H., COLLINS, P., Mayer, A., Lavergne, A., Wéry, M., Mni, M., Hego, A., Thuillier, V., Becker, G., Bahri, M. A., Plenevaux, A., Di Valentin, E., Oury, C., MOUTSCHEN, M., Delvenne, P., Paquot, N., & Rahmouni, S. (2021). Dual‑specificity phosphatase 3 deletion promotes obesity, non‑alcoholic steatohepatitis and hepatocellular carcinoma. Scientific Reports, 11, 5817. doi:10.1038/s41598-021-85089-6
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Radermecker, C., Hego, A., Delvenne, P., & Marichal, T. (2021). Identification and Quantitation of Neutrophil Extracellular Traps in Human Tissue Sections. Bio-protocol, 11 (18), 4159. doi:10.21769/BioProtoc.4159
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Anania, S., Peiffer, R., Rademaker, G., Hego, A., Thiry, M., Deldicque, L., Francaux, M., Maloujahmoum, N., Agirman, F., Bellahcene, A., Castronovo, V., & Peulen, O. (21 June 2020). Myoferlin is a yet unknown interactor of the mitochondrial dynamics’ machinery in pancreas cancer cells. Cancers, 12 (6), 1643. doi:10.3390/cancers12061643
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KAUX, J.-F., Libertiaux, V., Dupont, L., Colige, A., Denoël, V., LECUT, C., Hego, A., Gustin, M., Duwez, L., Oury, C., Gothot, A., Greimers, L., & Drion, P. (February 2020). Platelet-rich plasma (PRP) and tendon healing: comparison between fresh and frozen-thawed PRP. Platelets, 31 (2), 221-225. doi:10.1080/09537104.2019.1595563
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Anania, S., Rademaker, G., Peiffer, R., Hego, A., Deldicque, L., Maloujahmoum, N., Agirman, F., Bellahcene, A., Castronovo, V., & Peulen, O. (February 2020). Role of myoferlin in mitochondrial dynamics and metabolic fitness of pancreas cancer [Poster presentation]. BACR Annual Meeting 2020 - Cancer metastases: from bedside to bench, Brussels, Belgium.

Oury, C., MARECHAL, P., Donis, N., Hulin, A., Hego, A., TRIDETTI, J., Nguyen, M.-L., DULGHERU, R. E., Fillet, M., Nchimi Longang, A., & Lancellotti, P. (2020). Dexfenfluramine and Pergolide Cause Heart Valve Disease via Valve Metabolic Reprogramming and Ongoing Matrix Remodeling. International Journal of Molecular Sciences, 21 (11). doi:10.3390/ijms21114003
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Lombard, A., Di Gregorio, M., COPPIETERS, N., Di Valentin, E., Hego, A., Martin, D., & Rogister, B. (2020). Communicating hydrocephalus associated to ventral leptomeningeal invasion leads to precocious death in a glioblastoma orthotopic xenograft model. Neuro-Oncology Advances.
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Kautbally, S., Lepropre, S., Onselaer, M.-B., Le Rigoleur, A., Ginion, A., De Meester de Ravenstein, C., Ambroise, J., Boudjeltia, K. Z., Octave, M., WERA, O., Hego, A., PINCEMAIL, J., Cheramy-Bien, J.-P., Huby, T., Giera, M., Gerber, B., Pouleur, A.-C., Guigas, B., Vanoverschelde, J.-L., ... Beauloye, C. (September 2019). Platelet Acetyl-CoA Carboxylase Phosphorylation: A Risk Stratification Marker That Reveals Platelet-Lipid Interplay in Coronary Artery Disease Patients. JACC: Basic to Translational Science, 4 (5), 596-610. doi:10.1016/j.jacbts.2019.04.005
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Wéra, O., LECUT, C., Servais, L., Hego, A., Delierneux, C., Jiang, Z., Keutgens, A., Evans, R. J., Delvenne, P., Lancellotti, P., & Oury, C. (21 August 2019). P2X1 ion channel deficiency causes massive bleeding in inflamed intestine and increases thrombosis. Journal of Thrombosis and Haemostasis, 18 (1), 44-56. doi:10.1111/jth.14620
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Morimont, P., Habran, S., Desaive, T., BLAFFART, F., LAGNY, M.-G., AMAND, T., Dauby, P., Oury, C., LANCELLOTTI, P., Hego, A., Defraigne, J.-O., & LAMBERMONT, B. (2019). Extracorporeal CO2 removal and regional citrate anticoagulation in an experimental model of hypercapnic acidosis. Artificial Organs. doi:10.1111/aor.13431
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Wéra, O., Servais, L., Delierneux, C., Hego, A., LECUT, C., KEUTGENS, A., Delvenne, P., Nchimi Longang, A., Lancellotti, P., & Oury, C. (November 2018). P2X1 deficiency causes massive intestinal bleeding along with enhanced neutrophil-dependent thrombosis in colitis [Paper presentation]. Belgian Society on Thrombosis and Haemostasis BSTH 2018.

Oury, C., Wéra, O., Servais, L., Lancellotti, P., Hego, A., LECUT, C., Nchimi Longang, A., & Delvenne, P. (September 2018). A novel P2X1-G-CSF-CCL5 axis controls hemostasis via platelets and neutrophils in intestinal inflammation [Paper presentation]. 4th European Platelet Network Meeting.

Lepropre, S., Kautbally, S., Octave, M., Ginion, A., Onselaer, M.-B., Steinberg, G. R., Kemp, B. E., Hego, A., Wéra, O., Brouns, S., Swieringa, F., Giera, M., Darley-Usmar, V. M., Ambroise, J., Guigas, B., Heemskerk, J., Bertrand, L., Oury, C., Beauloye, C., & Horman, S. (2018). AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation. Blood, 132 (11), 1180-1192. doi:10.1182/blood-2018-02-831503
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Musumeci, L., Jacques, N., Hego, A., Nchimi Longang, A., Lancellotti, P., & Oury, C. (2018). Prosthetic Aortic Valves: Challenges and Solutions. Frontiers in Cardiovascular Medicine, 5, 46. doi:10.3389/fcvm.2018.00046
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Hulin, A., Hego, A., Lancellotti, P., & Oury, C. (2018). Advances in Pathophysiology of Calcific Aortic Valve Disease Propose Novel Molecular Therapeutic Targets. Frontiers in Cardiovascular Medicine, 5, 21. doi:10.3389/fcvm.2018.00021
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LAYIOS, N., Delierneux, C., Hego, A., HUART, J., GOSSET, C., LECUT, C., MAES, N., Geurts, P., Joly, A., LANCELLOTTI, P., Albert, A., DAMAS, P., GOTHOT, A., & Oury, C. (December 2017). Sepsis prediction in critically ill patients by platelet activation markers on ICU admission: a prospective pilot study. Intensive Care Medicine Experimental, 5 (1), 32. doi:10.1186/s40635-017-0145-2
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Wéra, O., Servais, L., Delierneux, C., Hego, A., LECUT, C., DELVENNE, P., Nchimi Longang, A., LANCELLOTTI, P., & Oury, C. (November 2017). P2X1 ion channel regulates neutrophil NETosis in colitis [Paper presentation]. BSTH 2017, Mechelen, Belgium.

Wéra, O., Delierneux, C., Servais, L., Hego, A., LECUT, C., DELVENNE, P., Nchimi Longang, A., LANCELLOTTI, P., & Oury, C. (July 2017). Interplay between platelets, neutrophils and coagulation in bleeding in a mouse model of inflammatory bowel disease [Poster presentation]. ISTH 2017, Berlin, Germany.

Wéra, O., Delierneux, C., Servais, L., Hego, A., LECUT, C., Nchimi Longang, A., Lancellotti, P., & Oury, C. (November 2016). P2X1 ion channel is critical for vascular integrity in inflammation [Poster presentation]. BSTH 2016, Mechelen, Belgium.

Wéra, O., Delierneux, C., Hego, A., LECUT, C., Servais, L., Nchimi Longang, A., Lancellotti, P., & Oury, C. (September 2016). P2X1 ion channel is critical for vascular integrity in inflammation [Paper presentation]. 3rd EUPLAN Conference, Bad Homburg, Germany.

Rahmouni, S., Hego, A., Delierneux, C., Wéra, O., Musumeci, L., Tautz, L., & Oury, C. (2016). Functional analysis of protein tyrosine phosphatases in thrombosis and haemostasis. In Protein Tyrosine Phosphatases: Methods and Protocols (pp. 301-30). New York, United States: Springer Science.
Peer reviewed

Wéra, O., Delierneux, C., Hego, A., LECUT, C., Servais, L., Nchimi Longang, A., LANCELLOTTI, P., & Oury, C. (2016). P2X1 ion channel is critical for vascular integrity in inflammation [Poster presentation]. ESC CONGRESS, ROMA, Italy.

Oury, C., Servais, L., Bouznad, N., Hego, A., Nchimi Longang, A., & Lancellotti, P. (2016). MicroRNAs in Valvular Heart Diseases: Potential Role as Markers and Actors of Valvular and Cardiac Remodeling. International Journal of Molecular Sciences, 17 (7). doi:10.3390/ijms17071120
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LECUT, C., PETERS, P., FIORE, M., Delierneux, C., JOIRET, M., Hego, A., Oury, C., & GOTHOT, A. (20 November 2015). Phenotypic characterization of a patient with Glanzmann Thrombasthenia caused by a novel homozygous mutation in the ITGA2B gene [Poster presentation]. 23ème congrès annuel de la Société Belge de Thrombose-Hémostase, Mechelen, Belgium.

Oury, C., Hego, A., & LANCELLOTTI, P. (November 2015). L'image du mois : Le processus thrombotique sous la loupe (microscopie intravitale). Revue Médicale de Liège, 70 (11), 537-539.
Peer reviewed

Wéra, O., Delierneux, C., Hego, A., LECUT, C., Servais, L., LANCELLOTTI, P., & Oury, C. (November 2015). P2X1 ion channels limit the formation of extra-intestinal neutrophil-rich thrombi in acute colitis [Poster presentation]. Belgian Society of Thrombosis and Hemostasis, Mechelen, Belgium.

Delierneux, C., LAYIOS, N., Hego, A., HUART, J., Joly, A., Geurts, P., DAMAS, P., LECUT, C., GOTHOT, A., & Oury, C. (19 October 2015). Elevated basal levels of platelet-bound fibrinogen predict the occurrence of sepsis in ICU: a prospective study [Paper presentation]. Belgian Society on Thrombosis and Haemostasis (BSTH), Lamot, Belgium.

Rahmouni, S., MUSUMECI, L., Kuijpers, M. J., Gilio, K., Hego, A., Theatre, E., Senis, Y., Heemskerk, J., Thiry, M., Tautz, L., & Oury, C. (24 June 2015). DUSP3 Phosphatase Deficiency or Inhibition Limits Platelet Activation and Arterial Thrombosis [Paper presentation]. ISTH 2015 Congress, Toronto, Canada.

Delierneux, C., LAYIOS, N., Hego, A., HUART, J., Joly, A., Geurts, P., DAMAS, P., LECUT, C., GOTHOT, A., & Oury, C. (23 June 2015). Prospective analysis of platelet activation markers to predict severe infection and mortality in intensive care units [Poster presentation]. XXV Congress of the International Society on Thrombosis and Haemostasis (ISTH), Toronto, Canada.

Delierneux, C., Hego, A., LECUT, C., Vandereyken, M., MUSUMECI, L., Rahmouni, S., BOURS, V., Lancellotti, P., & Oury, C. (22 June 2015). CLEC-2 is required for the activation of mouse platelets by bacterial DNA mimetics [Paper presentation]. ISTH 2015 Congress, Toronto, Canada.

Delierneux, C., Hego, A., LECUT, C., Vandereyken, M., MUSUMECI, L., Rahmouni, S., BOURS, V., LANCELLOTTI, P., & Oury, C. (22 June 2015). CLEC-2 is required for the activation of mouseplatelets by bacterial DNA mimetics [Paper presentation]. ISTH 2015 Congress, Toronto, Canada.

Lancellotti, P., NCHIMI LONGANG, A., Hego, A., DULGHERU, R. E., Delvenne, P., Drion, P., & Oury, C. (19 June 2015). High-dose oral intake of serotonin induces valvular heart disease in rabbits. International Journal of Cardiology, 197, 72-75. doi:10.1016/j.ijcard.2015.06.035
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Musumeci, L., Kuijpers, M., Gilio, K., Hego, A., Theatre, E., Maurissen, L., Vandereyken, M., Diogo, C., LECUT, C., Guilmain, W., Bobkova, E., Eble, J., Dahl, R., Drion, P., Rascon, J., Mostofi, Y., Yuan, H., Sergienko, E., Chung, T., ... Rahmouni, S.*. (17 February 2015). DUSP3 Phosphatase Deficiency or Inhibition Limit Platelet Activation and Arterial Thrombosis. Circulation, 131 (7), 656-68. doi:10.1161/CIRCULATIONAHA.114.010186
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Delierneux, C., Hego, A., LECUT, C., Vandereyken, M., Musumeci, L., Rahmouni, S., Thiry, M., Compère, P., BOURS, V., Lancellotti, P., & Oury, C. (27 January 2015). Bacterial DNA mimetics activate platelets and promote thrombosis via CLEC-2 [Poster presentation]. GIGA-DAY: Current advances in medical genetics and genomics, Liège, Belgium.

Oury, C., LECUT, C., Hego, A., Wéra, O., & Delierneux, C. (16 January 2015). Purinergic control of inflammation and thrombosis: Role of P2X1 receptors. Computational and Structural Biotechnology Journal, 13, 106-110. doi:10.1016/j.csbj.2014.11.008
Peer Reviewed verified by ORBi

LANCELLOTTI, P., NCHIMI LONGANG, A., Delierneux, C., Hego, A., Gosset, C., Gothot, A., TSHIBANDA, L., & Oury, C. (2015). Biological Effects of Cardiac Magnetic Resonance on Human Blood Cells. Circulation: Cardiovascular Imaging, 8 (9). doi:10.1161/CIRCIMAGING.115.003697
Peer Reviewed verified by ORBi

Servais, L., Bouznad, N., Jacques, S., Delierneux, C., Hego, A., GOTHOT, A., & Oury, C. (2015). Platelets contribute to colitis-associated carcinogenesis : evidence from a mouse model [Poster presentation]. Giga Cancer Day 2015, Belgium.

LAYIOS, N., Delierneux, C., Hego, A., HUART, J., Joly, A., Geurts, P., DAMAS, P., LECUT, C., Gothot, A., & Oury, C. (2015). Erratum: Elevated basal levels of circulating activated platelets predict ICU-acquired sepsis and mortality: a prospective study. Critical Care, 19 (1), 301. doi:10.1186/s13054-015-1005-7
Peer Reviewed verified by ORBi

Oury, C., Hego, A., & Lancellotti, P. (2015). L'image du mois: Le processus thrombotique sous la loupe (microscopie intravitale). Revue Médicale de Liège, 70 (11), 537-539.
Peer reviewed

LAYIOS, N., GOSSET, C., Delierneux, C., Hego, A., HUART, J., Joly, A., Geurts, P., DAMAS, P., Oury, C., & Gothot, A. (2015). Erratum: Prospective immune profiling in critically ill adults: before, during and after severe sepsis and septic shock. Critical Care, 19 (1), 300. doi:10.1186/s13054-015-1006-6
Peer Reviewed verified by ORBi

LAYIOS, N., GOSSET, C., Delierneux, C., Hego, A., HUART, J., DAMAS, P., Oury, C., & GOTHOT, A. (2015). Prospective immune profiling in critically ill adults : before, during and after severe sepsis shock. Critical Care, 19 (1).

Servais, L., Bouznad, N., Jacques, S., Delierneux, C., Hego, A., GOTHOT, A., & Oury, C. (November 2014). Platelets contribute to colitis-associated carcinogenesis : evidence from a mouse model [Poster presentation]. BSTH 2014, Belgium.

Darbousset, R., Delierneux, C., Mezouar, S., Hego, A., LECUT, C., Guillaumat, I., Riederer, M., Evans, R., Dignat-George, F., Panicot-Dubois, L., Oury, C., & Dubois, C. (16 October 2014). P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice. Blood, 124, 2575-2585. doi:10.1182/blood-2014-04-571679
Peer Reviewed verified by ORBi

Servais, L., Bouznad, N., Jacques, S., Delierneux, C., Hego, A., GOTHOT, A., & Oury, C. (May 2014). Assessing the contribution of platelets to colorectal tumor growth in a mouse model of colitis-associated cancer [Poster presentation]. Giga Cancer Day.

JOSSE, C., Bouznad, N., Geurts, P., Irrthum, A., Huynh-Thu, V. A., Servais, L., Hego, A., Delvenne, P., Bours, V., & Oury, C. (2014). Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis. American Journal of Physiology - Gastrointestinal and Liver Physiology, 306, 229-43. doi:10.1152/ajpgi.00484.2012
Peer Reviewed verified by ORBi

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