Bruyere, D., RONCARATI, P., Lebeau, A., Lerho, T., Poulain, F., Hendrick, E., Pilard, C., Reynders, C., Ancion, M., Luyckx, M., Renard, M., Jacob, Y., Twizere, J.-C., Peiffer, R., Peulen, O., Delvenne, P., Hubert, P., McBride, A., Gillet, N., ... Herfs, M. (2023). Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair. Theranostics, 13 (3), 1130 - 1149. doi:10.7150/thno.78091 Peer Reviewed verified by ORBi |
Porquet, F., Weidong, L., Jehasse, K., Gazon, H., Kondili, M., Blacher, S., Massotte, L., Di Valentin, E., Furling, D., Gillet, N., Klein, A. F., Seutin, V., & Willems, L. (2023). Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy: Nucleic Acids, 32, 857 - 871. doi:10.1016/j.omtn.2023.05.007 Peer Reviewed verified by ORBi |
Faure-Dupuy, S.* , Riedl, T.* , Rolland, M.* , Hizir, Z., Reisinger, F., Neuhaus, K., Schuehle, S., Remouchamps, C., Gillet, N., Schönung, M., Stadler, M., Wettengel, J., Barnault, R., Parent, R., Schuster, L. C., Farhat, R., Prokosch, S., Leuchtenberger, C., Öllinger, R., ... Heikenwälder, M.*. (December 2021). Control of APOBEC3B induction and cccDNA decay by NF-κB and miR-138-5p. JHEP Reports, 3 (6), 100354. doi:10.1016/j.jhepr.2021.100354 Peer reviewed * These authors have contributed equally to this work. |
Bielarz, V. R., Willemart, K. V., Avalosse, N. M., Swert, K., Lotfi, R., Lejeune, N. M., Poulain, F., Ninanne, N., Gilloteaux, J., Gillet, N., & Nicaise, C. (May 2021). Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection. Brain Research, 1758, 147344. doi:10.1016/j.brainres.2021.147344 Peer Reviewed verified by ORBi |
Safari, R., Hamaïdia, M., De Brogniez, A., Gillet, N., & Willems, L. (2017). Cis-drivers and trans-drivers of bovine leukemia virus oncogenesis. Current Opinion in Virology, 26, 15-19. doi:10.1016/j.coviro.2017.06.012 Peer Reviewed verified by ORBi |
Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (28 April 2016). Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo. PLoS Pathogens, 12 (4), 1005588. doi:10.1371/journal.ppat.1005588 Peer Reviewed verified by ORBi |
Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (18 April 2016). Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo [Poster presentation]. AACR American Association for Cancer Research Annual meeting 2016, New Orleans, United States. |
Gillet, N., & Willems, L. (2016). Whole genome sequencing of 51 breast cancers reveals that tumors are devoid of bovine leukemia virus DNA. Retrovirology, 13:75. doi:10.1186/s12977-016-0308-3 Peer Reviewed verified by ORBi |
Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (18 December 2015). Bovine leukemia virus microRNAs regulate replication and contribute to oncogenesis in vivo [Paper presentation]. Third annual meeting Belgian Society for Virology. |
Barez, P.-Y., De Brogniez, A., Carpentier, A., Gazon, H., Gillet, N., Gutiérrez, G., Hamaïdia, M., Jacques, J.-R., Perike, S., Neelature Sriramareddy, S., Renotte, N., Staumont, B., Reichert, M., Trono, K., & Willems, L. (24 November 2015). Recent advances in BLV research. Viruses, 7 (11), 6080-6088. doi:10.3390/v7112929 Peer Reviewed verified by ORBi |
Carpentier, A., Barez, P.-Y., Hamaïdia, M., Gazon, H., De Brogniez, A., Perike, S., Gillet, N., & Willems, L. (07 July 2015). Modes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and Persistence. Viruses, 7, 3603-3624. doi:10.3390/v7072793 Peer Reviewed verified by ORBi |
Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (19 June 2015). The bovine leukemia virus microRNAs are dispensable for infection but contribute to viral replication in the natural host [Paper presentation]. 17th International Conference on Human Retrovirology: HTLV & Related Viruses, Trois ilets, Martinique, France. |
Willems, L., & Gillet, N. (11 June 2015). APOBEC3 Interference during Replication of Viral Genomes. Viruses, 7, 2999-3018. doi:10.3390/v7062757 Peer Reviewed verified by ORBi |
De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Cosse, J.-P., Gillet, N., Callebaut, I., Reichert, M., & Willems, L. (11 February 2015). Risk of emergence of a hyperpathogenic bovine leukemia virus by mutation of a single envelope N-linked glycosylation site [Poster presentation]. Cancer Resaerch and Televie: the challenge for the next 10 years, Bruxelles, Belgium. |
De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Cosse, J.-P., Gillet, N., Callebaut, I., Reichert, M., & Willems, L. (2015). Mutation of a Single Envelope N-linked Glycosylation Site Enhances the Pathogenicity of Bovine Leukemia Virus. Journal of Virology, 89 (17), 8945-8956. doi:10.1128/JVI.00261-15 Peer Reviewed verified by ORBi |
Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (2015). The bovine leukemia virus microRNAs permit escape from innate immune response and contribute to viral replication in the natural host. Retrovirology, 12. Peer Reviewed verified by ORBi |
De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Gillet, N., Callebaut, I., Reichert, M., & Willems, L. (08 December 2014). Risk of emergence of a hyperpathogenic bovine leukemia virus by mutation of a single envelope N-linked glycosylation site [Paper presentation]. Second annual meeting Belgian Society for Virology, Bruxelles, Belgium. |
De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Gillet, N., Reichert, M., & Willems, L. (05 June 2014). A Single Envelope N-linked Glycosylation Site Defines Hyperpathogenicity of Bovine Leukemia Virus [Paper presentation]. HERN in Rome a translational approach, Rome, Italy. |
Gillet, N., geronimo, G., rodriguez, S., De Brogniez, A., Renotte, N., alvarez, I., trono, K., & Willems, L. (April 2014). Massive Depletion of Bovine Leukemia Virus Proviral Clones Located in Genomic Transcriptionally Active Sites During Primary Infection [Poster presentation]. American Association for Cancer Research annual meeting 2014, San Diego, United States. |
Laydon, D. J., Melamed, A., Sim, A., Gillet, N., Sim, K., Darko, S., Kroll, J. S., Douek, D. C., Price, D. A., Bangham, C. R. M., & Asquith, B. (2014). Quantification of HTLV-1 Clonality and TCR Diversity. PLoS Computational Biology, 10 (6), 1003646. doi:10.1371/journal.pcbi.1003646 Peer Reviewed verified by ORBi |
Gutierrez, G., Rodriguez, S. M., De Brogniez, A., Gillet, N., Golime, R., Burny, A., Jaworski, J.-P., Alvarez, I., Vagnoni, L., Trono, K., & Willems, L. (2014). Vaccination against delta-Retroviruses: The Bovine Leukemia Virus Paradigm. Viruses, 6 (6), 2416-2427. doi:10.3390/v6062416 Peer Reviewed verified by ORBi |
De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Gillet, N., Pritsh, O., Tomé, L., Reichert, M., & Willems, L. (2014). Hyper-replicative bovine leukemia virus by mutation of an envelope N-linked glycosylation site. Retrovirology, 11 (1), 141. doi:10.1186/1742-4690-11-S1-P141 Peer Reviewed verified by ORBi |
Gillet, N., Gutiérrez, G., Rodriguez, S., De Brogniez, A., Renotte, N., Alvarez, I., Trono, K., & Willems, L. (29 June 2013). Massive Depletion of Bovine Leukemia Virus Proviral Clones Located in Genomic Transcriptionally Active Sites During Primary Infection [Paper presentation]. 16th International Conference on Human Retrovirology HTLV and Related Viruses, Montreal, Canada. |
Melamed, A., Laydon, D. J., Gillet, N., Tanaka, Y., Taylor, G. P., & Bangham, C. R. M. (2013). Genome-wide Determinants of Proviral Targeting, Clonal Abundance and Expression in Natural HTLV-1 Infection. PLoS Pathogens, 9 (3), 1003271. doi:10.1371/journal.ppat.1003271 Peer Reviewed verified by ORBi |
Gillet, N., Cook, L., Laydon, D. J., Hlela, C., Verdonck, K., Alvarez, C., Gotuzzo, E., Clark, D., Farre, L., Bittencourt, A., Asquith, B., Taylor, G. P., & Bangham, C. R. M. (2013). Strongyloidiasis and Infective Dermatitis Alter Human T Lymphotropic Virus-1 Clonality in vivo. PLoS Pathogens, 9 (4), 1003263. doi:10.1371/journal.ppat.1003263 Peer Reviewed verified by ORBi |
Gillet, N., Gutiérrez, G., Rodriguez, S., De Brogniez, A., Renotte, N., Alvarez, I., Trono, K., & Willems, L. (2013). Massive Depletion of Bovine Leukemia Virus Proviral Clones Located in Genomic Transcriptionally Active Sites During Primary Infection. PLoS Pathogens, 9 (10). doi:10.1371/journal.ppat.1003687 Peer Reviewed verified by ORBi |
Gillet, N., Carpentier, A., Barez, P.-Y., & Willems, L. (21 December 2012). WIP1 deficiency inhibits HTLV-1 Tax oncogenesis: novel therapeutic prospects for treatment of ATL? Retrovirology, 9 (1), 115. doi:10.1186/1742-4690-9-115 Peer Reviewed verified by ORBi |
Gillet, N., Vandermeers, F., De Brogniez, A., Florins, A., Nigro, A., François, C., Bouzar, A.-B., Verlaeten, O., Stern, E., Lambert, D., Wouters, J., & Willems, L. (2012). Chemoresistance to Valproate Treatment of Bovine Leukemia Virus-Infected Sheep; Identification of Improved HDAC Inhibitors. Pathogens, (2012-1), 65-82. doi:10.3390/pathogens1020065 Peer Reviewed verified by ORBi |
Berry, C. C., Gillet, N., Melamed, A., Gormley, N., Bangham, C. R. M., & Bushman, F. D. (2012). Estimating abundances of retroviral insertion sites from DNA fragment length data. Bioinformatics, 28 (6), 755-62. doi:10.1093/bioinformatics/bts004 Peer Reviewed verified by ORBi |
Olindo, S., Belrose, G., Gillet, N., Rodriguez, S., Boxus, M., Verlaeten, O., Asquith, B., Bangham, C., Signaté, A., Smadja, D., Lezin, A., Césaire, R., & Willems, L. (08 December 2011). Safety of long-term treatment of HAM/TSP patients with valproic acid. Blood, 118 (24), 6306-6309. doi:10.1182/blood-2011-04-349910 Peer Reviewed verified by ORBi |
Rodriguez, S., Florins, A.-F., Gillet, N., De Brogniez, A., Sanchez-Alcaraz, M.-T., Boxus, M., Boulanger, F., Gutiérrez, G., Trono, K., Alvarez, I., Vagnoni, L., & Willems, L. (19 July 2011). Preventive and Therapeutic Strategies for Bovine Leukemia Virus: Lessons for HTLV. Viruses, 3 (7), 1210-1248. doi:10.3390/v3071210 Peer Reviewed verified by ORBi |
Villaudy, J., Wencker, M., Gadot, N., Gillet, N., Scoazec, J.-Y., Gazzolo, L., Manz, M. G., Bangham, C. R. M., & Dodon, M. D. (2011). HTLV-1 propels thymic human T cell development in "human immune system" Rag2(-)/(-) gamma c(-)/(-) mice. PLoS Pathogens, 7 (9), 1002231. doi:10.1371/journal.ppat.1002231 Peer Reviewed verified by ORBi |
Gillet, N., Malani, N., Melamed, A., Gormley, N., Carter, R., Bentley, D., Berry, C., Bushman, F. D., Taylor, G. P., & Bangham, C. R. M. (2011). The host genomic environment of the provirus determines the abundance of HTLV-1-infected T-cell clones. Blood, 117 (11), 3113-22. doi:10.1182/blood-2010-10-312926 Peer Reviewed verified by ORBi |
Gillet, N., Malani, N., Berry, C., Frederick, B., Gormley, N., Melamed, A., Taylor, G., & Bangham, C. (May 2010). How the genomic environment of the HTLV-1 provirus impacts on clone fitness [Paper presentation]. HTLV European Research Network (HERN) meeting, Lyon, France. |
Olindo, S., Belrose, G., Lezin, A., Gillet, N., Defoiche, J., Rodriguez, S., Signaté, A., Verlaeten, O., Smadja, D., Césaire, R., & Willems, L. (01 July 2009). Long-term treatment with valproic acid does not alleviate the condition of HAM/TSP. AIDS Research and Human Retroviruses, 25 (11), 21. Peer Reviewed verified by ORBi |
Lezin, A., Olindo, S., Belrose, G., Signate, A., Cesaire, R., Smadja, D., Macallan, D., Asquith, B., Bangham, C., Bouzar, A., Gillet, N., Defoiche, J., Florins, A.-F., Verlaeten, O., Burny, A., & Willems, L. (2009). Gene activation therapy: from the BLV model to HAM/TSP patients. Frontiers in Bioscience. Scholar Edition, 1, 205-15. doi:10.2741/e20 Peer Reviewed verified by ORBi |
Florins, A.-F., Gillet, N., Boxus, M., Kerkhofs, P., Kettmann, R., & Willems, L. (2007). Even attenuated bovine leukemia virus proviruses can be pathogenic in sheep. Journal of Virology, 81 (18), 10195-200. doi:10.1128/JVI.01058-07 Peer Reviewed verified by ORBi |
Lagneaux, L., Gillet, N., Stamatopoulos, B., Delforge, A., Dejeneffe, M., Massy, M., Meuleman, N., Kentos, A., Martiat, P., Willems, L., & Bron, D. (2007). Valproic acid induces apoptosis in chronic lymphocytic leukemia cells through activation of the death receptor pathway and potentiates TRAIL response. Experimental Hematology, 35 (10), 1527-37. doi:10.1016/j.exphem.2007.06.014 Peer reviewed |
Gillet, N. (2007). Développement d'une stratégie thérapeutique basée sur le levée de la latence des virus de la leucémie bovine et T lymphotrope humain [Doctoral thesis, ULiège. GxABT - Liège Université. Gembloux Agro-Bio Tech]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/139635 |
Florins, A.-F., Gillet, N., Boxus, M., Verlaeten, O., Nigro, A., Vandermeers, F., Burteau, C., Balon, H., Bouzar, A., Defoiche, J., Burny, A., Kettmann, R., & Willems, L. (2007). Dynamique cellulaire de la pathogenèse induite par le virus de la leucémie bovine. Virologie. doi:10.1684/vir.2007.0134 Peer reviewed |
Lezin, A., Gillet, N., Olindo, S., Signate, A., Grandvaux, N., Verlaeten, O., Belrose, G., de Carvalho Bittencourt, M., Hiscott, J., Asquith, B., Burny, A., Smadja, D., Cesaire, R., & Willems, L. (2007). Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients. Blood, 110 (10), 3722-8. doi:10.1182/blood-2007-04-085076 Peer Reviewed verified by ORBi |
Gillet, N., Kettmann, R., & Willems, L. (2007). Homologies entre les deux retrovirus BLV et HTLV-1 et developpement d'une nouvelle approche therapeutique basee sur la levee de la latence virale. Biotechnologie, Agronomie, Société et Environnement, 11 (2), 151-157. Peer Reviewed verified by ORBi |
Gillet, N., Florins, A.-F., Boxus, M., Burteau, C., Nigro, A., Vandermeers, F., Balon, H., Bouzar, A., Defoiche, J., Burny, A., Reichert, M., Kettmann, R., & Willems, L. (2007). Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human. Retrovirology, 4 (1), 18. doi:10.1186/1742-4690-4-18 Peer Reviewed verified by ORBi |
Florins, A.-F., Gillet, N., Asquith, B., Boxus, M., Burteaux, C., Twizere, J.-C., Urbain, P., Vandermeers, F., Debacq, C., Sanchez-alcaraz, M. T., Schwartz-Cornil, I., Kerkhofs, P., Jean, G., Thewis, A., Hay, J., Mortreux, F., Wattel, E., Reichert, M., Burny, A., ... Willems, L. (2007). Cell dynamics and immune response to BLV infection: a unifying model. Frontiers in Bioscience: A Journal and Virtual Library, 12, 1520-1531. doi:10.2741/2165 Peer Reviewed verified by ORBi |
Asquith, B., Debacq, C., Florins, A.-F., Gillet, N., Sanchez-Alcaraz, T., Mosley, A., & Willems, L. (2006). Quantifying lymphocyte kinetics in vivo using carboxyfluorescein diacetate succinimidyl ester (CFSE). Proceedings of the Royal Society. Biological Sciences, 273 (1590), 1165-71. doi:10.1098/rspb.2005.3432 Peer Reviewed verified by ORBi |
Florins, A.-F., Gillet, N., Asquith, B., Debacq, C., Jean, G., Schwartz-Cornil, I., Bonneau, M., Burny, A., Reichert, M., Kettmann, R., & Willems, L. (2006). Spleen-dependent turnover of CD11b peripheral blood B lymphocytes in bovine leukemia virus-infected sheep. Journal of Virology, 80 (24), 11998-2008. doi:10.1128/JVI.01447-06 Peer Reviewed verified by ORBi |
Debacq, C., Gillet, N., Asquith, B., Sanchez-Alcaraz, M. T., Florins, A.-F., Boxus, M., Schwartz-Cornil, I., Bonneau, M., Jean, G., Kerkhofs, P., Hay, J., Thewis, A., Kettmann, R., & Willems, L. (2006). Peripheral blood B-cell death compensates for excessive proliferation in lymphoid tissues and maintains homeostasis in bovine leukemia virus-infected sheep. Journal of Virology, 80 (19), 9710-9719. doi:10.1128/JVI.01022-06 Peer Reviewed verified by ORBi |
Achachi, A.* , Florins, A.-F.* , Gillet, N.* , Debacq, C., Urbain, P., Foutsop, G. M., Vandermeers, F., Jasik, A., Reichert, M., Kerkhofs, P., Lagneaux, L., Burny, A., Kettmann, R., & Willems, L. (2005). Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo. Proceedings of the National Academy of Sciences of the United States of America, 102 (29), 10309-14. doi:10.1073/pnas.0504248102 Peer Reviewed verified by ORBi * These authors have contributed equally to this work. |