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Gillet Nicolas

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Main Referenced Co-authors
Willems, Luc  (37)
De Brogniez, Alix  (19)
Reichert, Michal (14)
Florins, Arnaud-Francois  (10)
Asquith, Becca (9)
Main Referenced Keywords
Humans (8); Animals (7); BLV (6); Sheep (6); Bovine leukemia virus (5);
Main Referenced Disciplines
Oncology (19)
Immunology & infectious disease (11)
Biochemistry, biophysics & molecular biology (7)
Veterinary medicine & animal health (7)
Hematology (6)

Publications (total 47)

The most downloaded
608 downloads
Florins, A.-F., Gillet, N., Asquith, B., Boxus, M., Burteaux, C., Twizere, J.-C., Urbain, P., Vandermeers, F., Debacq, C., Sanchez-alcaraz, M. T., Schwartz-Cornil, I., Kerkhofs, P., Jean, G., Thewis, A., Hay, J., Mortreux, F., Wattel, E., Reichert, M., Burny, A., ... Willems, L. (2007). Cell dynamics and immune response to BLV infection: a unifying model. Frontiers in Bioscience: A Journal and Virtual Library, 12, 1520-1531. doi:10.2741/2165 https://hdl.handle.net/2268/20537

The most cited

288 citations (Scopus®)

Gillet, N., Florins, A.-F., Boxus, M., Burteau, C., Nigro, A., Vandermeers, F., Balon, H., Bouzar, A., Defoiche, J., Burny, A., Reichert, M., Kettmann, R., & Willems, L. (2007). Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human. Retrovirology, 4 (1), 18. doi:10.1186/1742-4690-4-18 https://hdl.handle.net/2268/10555

Porquet, F., Weidong, L., Jehasse, K., Gazon, H., Kondili, M., Blacher, S., Massotte, L., Di Valentin, E., Furling, D., Gillet, N., Klein, A. F., Seutin, V., & Willems, L. (2023). Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy: Nucleic Acids, 32, 857 - 871. doi:10.1016/j.omtn.2023.05.007
Peer Reviewed verified by ORBi

Bruyere, D., RONCARATI, P., Lebeau, A., Lerho, T., Poulain, F., Hendrick, E., Pilard, C., Reynders, C., Ancion, M., Luyckx, M., Renard, M., Jacob, Y., Twizere, J.-C., Peiffer, R., Peulen, O., Delvenne, P., Hubert, P., McBride, A., Gillet, N., ... Herfs, M. (2023). Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair. Theranostics, 13 (3), 1130 - 1149. doi:10.7150/thno.78091
Peer Reviewed verified by ORBi

Faure-Dupuy, S., Riedl, T., Rolland, M., Hizir, Z., Reisinger, F., Neuhaus, K., Schuehle, S., Remouchamps, C., Gillet, N., Schönung, M., Stadler, M., Wettengel, J., Barnault, R., Parent, R., Schuster, L. C., Farhat, R., Prokosch, S., Leuchtenberger, C., Öllinger, R., ... Heikenwälder, M.*. (December 2021). Control of APOBEC3B induction and cccDNA decay by NF-κB and miR-138-5p. JHEP Reports, 3 (6), 100354. doi:10.1016/j.jhepr.2021.100354
Peer reviewed
* These authors have contributed equally to this work.

Safari, R., Hamaïdia, M., De Brogniez, A., Gillet, N., & Willems, L. (2017). Cis-drivers and trans-drivers of bovine leukemia virus oncogenesis. Current Opinion in Virology, 26, 15-19. doi:10.1016/j.coviro.2017.06.012
Peer Reviewed verified by ORBi

Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (28 April 2016). Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo. PLoS Pathogens, 12 (4), 1005588. doi:10.1371/journal.ppat.1005588
Peer Reviewed verified by ORBi

Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (18 April 2016). Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo [Poster presentation]. AACR American Association for Cancer Research Annual meeting 2016, New Orleans, United States.

Gillet, N., & Willems, L. (2016). Whole genome sequencing of 51 breast cancers reveals that tumors are devoid of bovine leukemia virus DNA. Retrovirology, 13:75. doi:10.1186/s12977-016-0308-3
Peer Reviewed verified by ORBi

Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (18 December 2015). Bovine leukemia virus microRNAs regulate replication and contribute to oncogenesis in vivo [Paper presentation]. Third annual meeting Belgian Society for Virology.

Barez, P.-Y., De Brogniez, A., Carpentier, A., Gazon, H., Gillet, N., Gutiérrez, G., Hamaïdia, M., Jacques, J.-R., Perike, S., Neelature Sriramareddy, S., Renotte, N., Staumont, B., Reichert, M., Trono, K., & Willems, L. (24 November 2015). Recent advances in BLV research. Viruses, 7 (11), 6080-6088. doi:10.3390/v7112929
Peer Reviewed verified by ORBi

Carpentier, A., Barez, P.-Y., Hamaïdia, M., Gazon, H., De Brogniez, A., Perike, S., Gillet, N., & Willems, L. (07 July 2015). Modes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and Persistence. Viruses, 7, 3603-3624. doi:10.3390/v7072793
Peer Reviewed verified by ORBi

Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (19 June 2015). The bovine leukemia virus microRNAs are dispensable for infection but contribute to viral replication in the natural host [Paper presentation]. 17th International Conference on Human Retrovirology: HTLV & Related Viruses, Trois ilets, Martinique, France.

Willems, L., & Gillet, N. (11 June 2015). APOBEC3 Interference during Replication of Viral Genomes. Viruses, 7, 2999-3018. doi:10.3390/v7062757
Peer Reviewed verified by ORBi

De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Cosse, J.-P., Gillet, N., Callebaut, I., Reichert, M., & Willems, L. (11 February 2015). Risk of emergence of a hyperpathogenic bovine leukemia virus by mutation of a single envelope N-linked glycosylation site [Poster presentation]. Cancer Resaerch and Televie: the challenge for the next 10 years, Bruxelles, Belgium.

Gillet, N., Hamaïdia, M., De Brogniez, A., Gutierrez, G., Renotte, N., Reichert, M., Trono, K., & Willems, L. (2015). The bovine leukemia virus microRNAs permit escape from innate immune response and contribute to viral replication in the natural host. Retrovirology, 12.
Peer Reviewed verified by ORBi

De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Cosse, J.-P., Gillet, N., Callebaut, I., Reichert, M., & Willems, L. (2015). Mutation of a Single Envelope N-linked Glycosylation Site Enhances the Pathogenicity of Bovine Leukemia Virus. Journal of Virology, 89 (17), 8945-8956. doi:10.1128/JVI.00261-15
Peer Reviewed verified by ORBi

De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Gillet, N., Callebaut, I., Reichert, M., & Willems, L. (08 December 2014). Risk of emergence of a hyperpathogenic bovine leukemia virus by mutation of a single envelope N-linked glycosylation site [Paper presentation]. Second annual meeting Belgian Society for Virology, Bruxelles, Belgium.

De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Gillet, N., Reichert, M., & Willems, L. (05 June 2014). A Single Envelope N-linked Glycosylation Site Defines Hyperpathogenicity of Bovine Leukemia Virus [Paper presentation]. HERN in Rome a translational approach, Rome, Italy.

Gillet, N., geronimo, G., rodriguez, S., De Brogniez, A., Renotte, N., alvarez, I., trono, K., & Willems, L. (April 2014). Massive Depletion of Bovine Leukemia Virus Proviral Clones Located in Genomic Transcriptionally Active Sites During Primary Infection [Poster presentation]. American Association for Cancer Research annual meeting 2014, San Diego, United States.

Gutierrez, G., Rodriguez, S. M., De Brogniez, A., Gillet, N., Golime, R., Burny, A., Jaworski, J.-P., Alvarez, I., Vagnoni, L., Trono, K., & Willems, L. (2014). Vaccination against delta-Retroviruses: The Bovine Leukemia Virus Paradigm. Viruses, 6 (6), 2416-2427. doi:10.3390/v6062416
Peer Reviewed verified by ORBi

De Brogniez, A., Bouzar, A.-B., Jacques, J.-R., Gillet, N., Pritsh, O., Tomé, L., Reichert, M., & Willems, L. (2014). Hyper-replicative bovine leukemia virus by mutation of an envelope N-linked glycosylation site. Retrovirology, 11 (1), 141. doi:10.1186/1742-4690-11-S1-P141
Peer Reviewed verified by ORBi

Laydon, D. J., Melamed, A., Sim, A., Gillet, N., Sim, K., Darko, S., Kroll, J. S., Douek, D. C., Price, D. A., Bangham, C. R. M., & Asquith, B. (2014). Quantification of HTLV-1 Clonality and TCR Diversity. PLoS Computational Biology, 10 (6), 1003646. doi:10.1371/journal.pcbi.1003646
Peer Reviewed verified by ORBi

Gillet, N., Gutiérrez, G., Rodriguez, S., De Brogniez, A., Renotte, N., Alvarez, I., Trono, K., & Willems, L. (29 June 2013). Massive Depletion of Bovine Leukemia Virus Proviral Clones Located in Genomic Transcriptionally Active Sites During Primary Infection [Paper presentation]. 16th International Conference on Human Retrovirology HTLV and Related Viruses, Montreal, Canada.

Melamed, A., Laydon, D. J., Gillet, N., Tanaka, Y., Taylor, G. P., & Bangham, C. R. M. (2013). Genome-wide Determinants of Proviral Targeting, Clonal Abundance and Expression in Natural HTLV-1 Infection. PLoS Pathogens, 9 (3), 1003271. doi:10.1371/journal.ppat.1003271
Peer Reviewed verified by ORBi

Gillet, N., Cook, L., Laydon, D. J., Hlela, C., Verdonck, K., Alvarez, C., Gotuzzo, E., Clark, D., Farre, L., Bittencourt, A., Asquith, B., Taylor, G. P., & Bangham, C. R. M. (2013). Strongyloidiasis and Infective Dermatitis Alter Human T Lymphotropic Virus-1 Clonality in vivo. PLoS Pathogens, 9 (4), 1003263. doi:10.1371/journal.ppat.1003263
Peer Reviewed verified by ORBi

Gillet, N., Gutiérrez, G., Rodriguez, S., De Brogniez, A., Renotte, N., Alvarez, I., Trono, K., & Willems, L. (2013). Massive Depletion of Bovine Leukemia Virus Proviral Clones Located in Genomic Transcriptionally Active Sites During Primary Infection. PLoS Pathogens, 9 (10). doi:10.1371/journal.ppat.1003687
Peer Reviewed verified by ORBi

Gillet, N., Carpentier, A., Barez, P.-Y., & Willems, L. (21 December 2012). WIP1 deficiency inhibits HTLV-1 Tax oncogenesis: novel therapeutic prospects for treatment of ATL? Retrovirology, 9 (1), 115. doi:10.1186/1742-4690-9-115
Peer Reviewed verified by ORBi

Gillet, N., Vandermeers, F., De Brogniez, A., Florins, A., Nigro, A., François, C., Bouzar, A.-B., Verlaeten, O., Stern, E., Lambert, D., Wouters, J., & Willems, L. (2012). Chemoresistance to Valproate Treatment of Bovine Leukemia Virus-Infected Sheep; Identification of Improved HDAC Inhibitors. Pathogens, (2012-1), 65-82. doi:10.3390/pathogens1020065
Peer Reviewed verified by ORBi

Berry, C. C., Gillet, N., Melamed, A., Gormley, N., Bangham, C. R. M., & Bushman, F. D. (2012). Estimating abundances of retroviral insertion sites from DNA fragment length data. Bioinformatics, 28 (6), 755-62. doi:10.1093/bioinformatics/bts004
Peer Reviewed verified by ORBi

Olindo, S., Belrose, G., Gillet, N., Rodriguez, S., Boxus, M., Verlaeten, O., Asquith, B., Bangham, C., Signaté, A., Smadja, D., Lezin, A., Césaire, R., & Willems, L. (08 December 2011). Safety of long-term treatment of HAM/TSP patients with valproic acid. Blood, 118 (24), 6306-6309. doi:10.1182/blood-2011-04-349910
Peer Reviewed verified by ORBi

Rodriguez, S., Florins, A.-F., Gillet, N., De Brogniez, A., Sanchez-Alcaraz, M.-T., Boxus, M., Boulanger, F., Gutiérrez, G., Trono, K., Alvarez, I., Vagnoni, L., & Willems, L. (19 July 2011). Preventive and Therapeutic Strategies for Bovine Leukemia Virus: Lessons for HTLV. Viruses, 3 (7), 1210-1248. doi:10.3390/v3071210
Peer Reviewed verified by ORBi

Villaudy, J., Wencker, M., Gadot, N., Gillet, N., Scoazec, J.-Y., Gazzolo, L., Manz, M. G., Bangham, C. R. M., & Dodon, M. D. (2011). HTLV-1 propels thymic human T cell development in "human immune system" Rag2(-)/(-) gamma c(-)/(-) mice. PLoS Pathogens, 7 (9), 1002231. doi:10.1371/journal.ppat.1002231
Peer Reviewed verified by ORBi

Gillet, N., Malani, N., Melamed, A., Gormley, N., Carter, R., Bentley, D., Berry, C., Bushman, F. D., Taylor, G. P., & Bangham, C. R. M. (2011). The host genomic environment of the provirus determines the abundance of HTLV-1-infected T-cell clones. Blood, 117 (11), 3113-22. doi:10.1182/blood-2010-10-312926
Peer Reviewed verified by ORBi

Gillet, N., Malani, N., Berry, C., Frederick, B., Gormley, N., Melamed, A., Taylor, G., & Bangham, C. (May 2010). How the genomic environment of the HTLV-1 provirus impacts on clone fitness [Paper presentation]. HTLV European Research Network (HERN) meeting, Lyon, France.

Olindo, S., Belrose, G., Lezin, A., Gillet, N., Defoiche, J., Rodriguez, S., Signaté, A., Verlaeten, O., Smadja, D., Césaire, R., & Willems, L. (01 July 2009). Long-term treatment with valproic acid does not alleviate the condition of HAM/TSP. AIDS Research and Human Retroviruses, 25 (11), 21.
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Lezin, A., Olindo, S., Belrose, G., Signate, A., Cesaire, R., Smadja, D., Macallan, D., Asquith, B., Bangham, C., Bouzar, A., Gillet, N., Defoiche, J., Florins, A.-F., Verlaeten, O., Burny, A., & Willems, L. (2009). Gene activation therapy: from the BLV model to HAM/TSP patients. Frontiers in Bioscience. Scholar Edition, 1, 205-15. doi:10.2741/e20
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Florins, A.-F., Gillet, N., Boxus, M., Verlaeten, O., Nigro, A., Vandermeers, F., Burteau, C., Balon, H., Bouzar, A., Defoiche, J., Burny, A., Kettmann, R., & Willems, L. (2007). Dynamique cellulaire de la pathogenèse induite par le virus de la leucémie bovine. Virologie. doi:10.1684/vir.2007.0134
Peer reviewed

Lezin, A., Gillet, N., Olindo, S., Signate, A., Grandvaux, N., Verlaeten, O., Belrose, G., de Carvalho Bittencourt, M., Hiscott, J., Asquith, B., Burny, A., Smadja, D., Cesaire, R., & Willems, L. (2007). Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients. Blood, 110 (10), 3722-8. doi:10.1182/blood-2007-04-085076
Peer Reviewed verified by ORBi

Gillet, N., Kettmann, R., & Willems, L. (2007). Homologies entre les deux retrovirus BLV et HTLV-1 et developpement d'une nouvelle approche therapeutique basee sur la levee de la latence virale. Biotechnologie, Agronomie, Société et Environnement, 11 (2), 151-157.
Peer Reviewed verified by ORBi

Lagneaux, L., Gillet, N., Stamatopoulos, B., Delforge, A., Dejeneffe, M., Massy, M., Meuleman, N., Kentos, A., Martiat, P., Willems, L., & Bron, D. (2007). Valproic acid induces apoptosis in chronic lymphocytic leukemia cells through activation of the death receptor pathway and potentiates TRAIL response. Experimental Hematology, 35 (10), 1527-37. doi:10.1016/j.exphem.2007.06.014
Peer reviewed

Gillet, N. (2007). Développement d'une stratégie thérapeutique basée sur le levée de la latence des virus de la leucémie bovine et T lymphotrope humain [Doctoral thesis, ULiège. GxABT - Liège Université. Gembloux Agro-Bio Tech]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/139635

Florins, A.-F., Gillet, N., Boxus, M., Kerkhofs, P., Kettmann, R., & Willems, L. (2007). Even attenuated bovine leukemia virus proviruses can be pathogenic in sheep. Journal of Virology, 81 (18), 10195-200. doi:10.1128/JVI.01058-07
Peer Reviewed verified by ORBi

Gillet, N., Florins, A.-F., Boxus, M., Burteau, C., Nigro, A., Vandermeers, F., Balon, H., Bouzar, A., Defoiche, J., Burny, A., Reichert, M., Kettmann, R., & Willems, L. (2007). Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human. Retrovirology, 4 (1), 18. doi:10.1186/1742-4690-4-18
Peer Reviewed verified by ORBi

Florins, A.-F., Gillet, N., Asquith, B., Boxus, M., Burteaux, C., Twizere, J.-C., Urbain, P., Vandermeers, F., Debacq, C., Sanchez-alcaraz, M. T., Schwartz-Cornil, I., Kerkhofs, P., Jean, G., Thewis, A., Hay, J., Mortreux, F., Wattel, E., Reichert, M., Burny, A., ... Willems, L. (2007). Cell dynamics and immune response to BLV infection: a unifying model. Frontiers in Bioscience: A Journal and Virtual Library, 12, 1520-1531. doi:10.2741/2165
Peer Reviewed verified by ORBi

Asquith, B., Debacq, C., Florins, A.-F., Gillet, N., Sanchez-Alcaraz, T., Mosley, A., & Willems, L. (2006). Quantifying lymphocyte kinetics in vivo using carboxyfluorescein diacetate succinimidyl ester (CFSE). Proceedings of the Royal Society. Biological Sciences, 273 (1590), 1165-71. doi:10.1098/rspb.2005.3432
Peer Reviewed verified by ORBi

Debacq, C., Gillet, N., Asquith, B., Sanchez-Alcaraz, M. T., Florins, A.-F., Boxus, M., Schwartz-Cornil, I., Bonneau, M., Jean, G., Kerkhofs, P., Hay, J., Thewis, A., Kettmann, R., & Willems, L. (2006). Peripheral blood B-cell death compensates for excessive proliferation in lymphoid tissues and maintains homeostasis in bovine leukemia virus-infected sheep. Journal of Virology, 80 (19), 9710-9719. doi:10.1128/JVI.01022-06
Peer Reviewed verified by ORBi

Florins, A.-F., Gillet, N., Asquith, B., Debacq, C., Jean, G., Schwartz-Cornil, I., Bonneau, M., Burny, A., Reichert, M., Kettmann, R., & Willems, L. (2006). Spleen-dependent turnover of CD11b peripheral blood B lymphocytes in bovine leukemia virus-infected sheep. Journal of Virology, 80 (24), 11998-2008. doi:10.1128/JVI.01447-06
Peer Reviewed verified by ORBi

Achachi, A.* , Florins, A.-F.* , Gillet, N.* , Debacq, C., Urbain, P., Foutsop, G. M., Vandermeers, F., Jasik, A., Reichert, M., Kerkhofs, P., Lagneaux, L., Burny, A., Kettmann, R., & Willems, L. (2005). Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo. Proceedings of the National Academy of Sciences of the United States of America, 102 (29), 10309-14. doi:10.1073/pnas.0504248102
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

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