Profil

Schurmans Stéphane

Département des sciences fonctionnelles (DSF) > Biochimie métabolique vétérinaire

GIGA Molecular Biology of Diseases - Functional Genetics

See author's contact details
ORCID
0000-0002-5579-3840
Main Referenced Co-authors
Lambert, P. H. (14)
Erneux, C. (13)
Merino, J. (13)
Parmentier, M. (13)
Vassart, G. (10)
Main Referenced Keywords
5-phosphatase (9); alloantigens (7); Inpp5e (7); primary cilium (7); mice (6);
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (103)
Genetics & genetic processes (73)
Human health sciences: Multidisciplinary, general & others (3)

Publications (total 108)

The most downloaded
537 downloads
Scoumanne, A., Molina Ortiz, P., Monteyne, D., Perez-Morga, D., Erneux, C., & Schurmans, S. (2016). Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice. Advances in Biological Regulation, 62, 1-10. doi:10.1016/j.jbior.2016.03.001 https://hdl.handle.net/2268/194708

The most cited

356 citations (Scopus®)

Parmentier, M., Libert, F., Schurmans, S., Schiffmann, S., Lefort, A., Eggerickx, D., Ledent, C., Mollereau, C., Gerard, C., Perret, J., Grootegoed, A., & Vassart, G. (1992). Expression of members of the putative olfactory receptor gene family in mammalian germ cells. Nature, 355, 453-455. doi:10.1038/355453a0 https://hdl.handle.net/2268/35338

Burniat, A., Noël, A., Colige, A., Vanderplasschen, A., de Kerchove d'Exaerde, A., Kupper Cardozo, A., Van Keymeulen, A., Moens, A., Bondue, A., Herpain, A., Marchant, A., Loumaye, A., Beck, B., Van den Heyden, B., Corvilain, B., Lakaye, B., Rogister, B., Malgrange, B., Michiels, C., ... Brunko, E. (2023). Cent scientifiques répliquent à SEA (Suppression des Expériences sur l’Animal vivant) et dénoncent sa désinformation. La Libre Belgique.

Fernandes, S., Srivastava, N., Pedicone, C., Sudan, R., Luke, E. A., Dungan, O. M., Pacherille, A., Meyer, S. T., Dormann, S., Schurmans, S., Jacobsen, E., Chisholm, J. D., & Kerr, W. G. (2023). Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment. iScience. doi:10.1016/j.isci.2023.106071
Peer Reviewed verified by ORBi

Moes, B., Li, H., Molina Ortiz, P., Radermecker, C., Rosu, A., Vande Catsyne, C.-A., Sayyed, S. A., Fontela Joao, Duque, M., Mostafa, A., Azzi, A., Barata Joao T., Merino Ramon, Xu, C., Desmet, C., & Schurmans, S. (2023). INPP5K controls the dynamic structure and signaling of wild type and mutated, leukemia-associated IL7 receptors. Blood, 141, 1708-1717. doi:10.1182/blood.2022017819
Peer Reviewed verified by ORBi

Ukhavov, K., Uytingco, C., Green, W., Zhang, L., Schurmans, S., & Martens, J. R. (01 March 2022). INPP5E controls ciliary localization of phospholipids and odor response in olfactory sensory neurons. Journal of Cell Science, 135 (5). doi:10.1242/jcs.258364
Peer Reviewed verified by ORBi

Schurmans, S., Vande Catsyne, C.-A., Desmet, C., & Moes, B. (2021). The phosphoinositide 5-phosphatase INPP5K: from gene structure to in vivo functions. Advances in Biological Regulation. doi:10.1016/j.jbior.2020.100760
Peer Reviewed verified by ORBi

Marongiu, L., Mingozzi, F., Cigni, C., Marzi, R., Di Gioia, M., Garrè, M., Parazzoli, D., Sironi, L., Collini, M., Sakaguchi, R., Morii, T., Crosti, M., Moro, M., Schurmans, S., Catelani, T., Rotem, R., Colombo, M., Shears, S., Prosperi, D., ... Granucci, F. (2021). Inositol-triphosphate 3-kinase B promotes calcium mobilization and the inflammatory activity of dendritic cells. Science Signaling. doi:10.1126/scisignal.aaz2120
Peer Reviewed verified by ORBi

Michael, M., McCormick, B., Anderson, K. E., Karmakar, U., Vermeren, M., Schurmans, S., Amour, A., & Vermeren, S. (2021). The 5-phosphatase SHIP2 promotes neutrophil chemotaxis and recruitment. Frontiers in Immunology. doi:10.3389/fimmu.2021.671756
Peer Reviewed verified by ORBi

Vande Catsyne, C.-A., Sayyed, S. A., Molina Ortiz, P., Moës, B., Communi, D., Muller, J., Heusschen, R., CAERS, J., Azzi, A., Erneux, C., & Schurmans, S. (2020). Altered chondrocyte differentiation, matrix mineralization and MEK-Erk1/2 signaling in an INPPL1 catalytic knock-out mouse model of opsismodysplasia. Advances in Biological Regulation, 76, 100651. doi:10.1016/j.jbior.2019.100651
Peer Reviewed verified by ORBi

Pal Singh, S., de Bruijn, M. J. W., Velaso Gago da Graça, C., Cornet, O. B. J., Rip, J., Stadhouders, R., Meijers, R. W. J., Schurmans, S., Kerr, W. G., ter Burg, J., Eldering, E., Langerak, A. W., Pillai, S. Y., & Hendriks, R. W. (2020). Overexpression of SH2-containing inositol phosphatase contributes to chronic lymphocytic leukemia survival. Journal of Immunology, 204, 360-374. doi:10.4049/jimmunol.1900153
Peer Reviewed verified by ORBi

Constable, S., Long, A. B., Floyd, K. A., Schurmans, S., & Caspary, T. (2020). The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling. Development. doi:10.1242/dev.183301
Peer reviewed

Chabrier, G., Hobson, S., Yuldasheva, N., Kearney, M. T., Schurmans, S., Pineda-Torra, I., & Gage, M. C. (2019). Aged insulin resistant macrophages reveal dysregulated cholesterol biosynthesis, a pro-inflammatory profile and reduced foam cell formation capacity. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/238491.

Guo, J., Otis, J. M., Suciu, S. K., Catalano, C., Xing, L., Constable, S., Wachten, D., Gupton, S., Lee, J., Lee, A., Blackley, K. H., Ptacek, T., Simon, J. M., Schurmans, S., Stuber, G. D., Caspary, T., & Anton, E. S. (2019). Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Developmental Cell, 51, 759-774. doi:10.1016/j.devcel.2019.11.005
Peer Reviewed verified by ORBi

Bakker, J., Balthazart, J., Baron, F., Beguin, Y., Bettendorff, L., Blanpain, C., Bureau, F., Caers, J., Cani, P., Cataldo, D., Cornil, C., Clercx, C., Cloots, R., Colige, A., Daube, G., De Backer, O., de Kerchove d'Exaerde, A., Desmecht, D., Desmet, C., ... Wittamer, V. (2018). La souris, le patient, et le faux expert. Décryptage d'une mystification. Le Vif. L'Express.

Molina Ortiz, P.* , Orban, T.* , Martin, M., Habets, A., Dequiedt, F.* , & Schurmans, S.*. (2018). Rasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism. PLoS Genetics. doi:10.1371/journal.pgen.1007195
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Erneux, C., & Schurmans, S. (2018). SHIP2. In S. Choi, Encyclopedia of Signaling Molecules (pp. 4944-4950). Springer.
Peer reviewed

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Watt, N., Gage, M., Patel, P., Viswambharan, H., Sukumar, P., Galloway, S., Yuldasheva, N., Imrie, H., Walker, A., Griffin, K., Makava, N., Skromna, A., Bridge, K., Beech, D., Schurmans, S., Wheatcroft, S., Kearney, M., & Cubbon, R. (2017). Endothelial SHIP2 suppresses Nox2 NADPH oxidase-dependent vascular oxidative stress, endothelial dysfunction and systemic insulin resistance. Diabetes, 66 (11), 2808-2821. doi:10.2337/db17-0062
Peer Reviewed verified by ORBi

Phua, S. C., Chiba, S., Suzuki, M., Su, E., Roberson, E. C., Pusapati, G. V., Schurmans, S., Setou, M., Rohatgi, R., Reiter, J. F., Ikegami, K., & Inoue, T. (2017). Dynamic Remodeling of membrane composition drives cell cycle through primary cilia excision. Cell, 168, 264-279. doi:10.1016/j.cell.2016.12.032
Peer Reviewed verified by ORBi

Sierra Potchanant, E., Cerabona, D., Sater, Z., He, Y., Sun, Z., Gehlhausen, J., Schurmans, S., Gayral, S., & Nalepa, G. (2017). INPP5E Preserves Genomic Stability through Regulation of Mitosis. Molecular and Cellular Biology, 37 (6), 500-516. doi:10.1128/MCB.00500-16
Peer Reviewed verified by ORBi

Sayyed, S. A., JOURET, F., Vermeersch, M., Pérez-Morga, D., & Schurmans, S. (2017). The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating ERM proteins activation. Kidney International. doi:10.1016/j.kint.2017.01.008
Peer Reviewed verified by ORBi

Scoumanne, A., Molina Ortiz, P., Monteyne, D., Perez-Morga, D., Erneux, C., & Schurmans, S. (2016). Specific expression and function of inositol 1,4,5-trisphosphate 3-kinase C (ITPKC) in wild type and knock-out mice. Advances in Biological Regulation, 62, 1-10. doi:10.1016/j.jbior.2016.03.001
Peer Reviewed verified by ORBi

Alphonse, M. P., Duong, T. T., Shumitzu, C., Hoang, L. T., McCrindle, B. W., Franco, A., Schurmans, S., Philpott, D. J., Hibberd, M. L., Burns, J. C., Kuijpers, T. W., & Yeung, R. S. M. (2016). Inositol-triphosphate-3-kinase C mediates inflammasome activation and treatment response in Kawasaki Disease. Journal of Immunology, 197, 3481-3489. doi:10.4049/jimmunol.1600388
Peer Reviewed verified by ORBi

Garcia-Gonzalo, F. R., Phua, S. C., Roberson, E. C., Garcia III, G., Abedin, M., Schurmans, S., Inoue, T., & Reiter, J. F. (2015). Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling. Developmental Cell, 34, 400-409. doi:10.1016/j.devcel.2015.08.001
Peer Reviewed verified by ORBi

Magnani, D., Morlé, L., Hasenpusch-Theil, K., Paschaki, M., Jacoby, M., Schurmans, S., Durand B, B., & Theil, T. (2015). The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating patterning of prethalamus and ventral telencephalon. Human Molecular Genetics, 24, 2578-2593. doi:10.1093/hmg/ddv021
Peer Reviewed verified by ORBi

Chavez, M., Van Sande, J., de Kerchove d'Exaerde, A., Schurmans, S., & Schiffmann, S. (2015). Modulation of ciliary phosphoinositide content regulates trafficking and Sonic hedgehog signaling output. Developmental Cell, 34, 338-350. doi:10.1016/j.devcel.2015.06.016
Peer Reviewed verified by ORBi

Schurmans, S., Polizzi, S., Scoumanne, A., Sayyed, S. A., & Molina Ortiz, P. (2015). The Ras/Rap GTPase activating protein RASA3 : from gene structure to in vivo functions. Advances in Biological Regulation, 57, 153-161. doi:10.1016/j.jbior.2014.09.006
Peer Reviewed verified by ORBi

Elong Edimo, W., Schurmans, S., Roger, P., & Erneux, C. (2014). SHIP2 signaling in normal and pathological situations: Its impact on cell proliferation. Advances in Biological Regulation, 54, 142-151. doi:10.1016/j.jbior.2013.09.002
Peer Reviewed verified by ORBi

Molina Ortiz, P., Polizzi, S., Ramery, E., Gayral, S., Delierneux, C., Oury, C., Iwashita, S., & Schurmans, S. (2014). Rasa3 Controls Megakaryocyte Rap1 Activation, Integrin Signaling and Differentiation into Proplatelet. PLoS Genetics, 10 (6), 1004420. doi:10.1371/journal.pgen.1004420
Peer Reviewed verified by ORBi

Pirottin, D., Schurmans, S., Francois, C., Farnir, F., Closset, R., Bureau, F., & Desmet, C. (2014). Generation and validation of a mouse model for conditional inactivation of PLAGL1. In Proceedings of the 4th edition : FARAH Day 2014.

Stygelbout, V., Leroy, K., Pouillon, V., Ando, K., D'Amico, E., Jia, Y., Luo, H. R., Duyckaerts, C., Erneux, C., Schurmans, S.* , & Brion, J.-P.*. (2014). Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology. Brain: a Journal of Neurology, 137, 537-52. doi:10.1093/brain/awt344
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pouillon, V., Maréchal, Y., Frippiat, C., Erneux, C., & Schurmans, S. (2013). Inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) controls survival, proliferation and cytokine production in mouse peripheral T cells. Advances in Biological Regulation, 53 (1), 39-50. doi:10.1016/j.jbior.2012.08.001
Peer Reviewed verified by ORBi

D'Amico, E., Gayral, S., Massart, C., Van Sande, J., Reiter, J. F., Dumont, J., Robaye, B., & Schurmans, S. (2013). Thyroid-specific inactivation of Kif3a alters TSH signaling pathway and leads to hypothyroidism. Journal of Molecular Endocrinology, 50, 375-387. doi:10.1530/JME-12-0219
Peer Reviewed verified by ORBi

Dubois, E., Jacoby, M., Blockmans, M., Pernot, E., Schiffmann, S. N., Foukas, L., Henquin, J.-C., Vanhaesebroeck, B., Erneux, C., & Schurmans, S. (2012). Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse. Cellular Signalling, 24, 1971-1980. doi:10.1016/j.cellsig.2012.06.012
Peer Reviewed verified by ORBi

D'Amico, E., Stygelbout, V., & Schurmans, S. (2012). The Spinner-IBMM mouse is a new spontaneous mutant in the Tmie gene. Genes and Genomics, 34, 107-110. doi:10.1007/s13258-011-0157-3
Peer Reviewed verified by ORBi

Pernot, E., Terryn, S., Cheong, S. C., Markadieu, N., Janas, S., Blockmans, M., Jacoby, M., Pouillon, V., Gayral, S., Rossier, B. C., Beauwens, R., Erneux, C., Devuyst, O., & Schurmans, S. (2011). The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system. Pflügers Archiv: European Journal of Physiology, 462, 871-883. doi:10.1007/s00424-011-1028-0
Peer Reviewed verified by ORBi

Schurmans, S., Pouillon, V., & Marechal, Y. (2011). Regulation of B cell survival, development and function by inositol 1,4,5-trisphosphate 3-kinase B (Itpkb). Advances in Enzyme Regulation, 51, 66-73. doi:10.1016/j.advenzreg.2010.08.001
Peer Reviewed verified by ORBi

Nguidjoe, E., Sokolow, S., Bigabwa, S., Pachera, N., D'Amico, E., Allagnat, F., Vanderwinden, J. M., Sener, A., Manto, M., Depreter, M., Mast, J., Joanny, G., Montanya, E., Rahier, J., Cardoso, A. K., Eizirik, D. L., Schurmans, S., & Herchuelz, A. (2011). Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass. Diabetes, 60, 2076-2085. doi:10.2337/db10-0924
Peer Reviewed verified by ORBi

Marechal, Y., Queant, S., Polizzi, S., Pouillon, V., & Schurmans, S. (2011). Inositol 1,4,5-trisphosphate 3-kinase B controls survival and prevents anergy in B cells. Immunobiology, 216, 103-109. doi:10.1016/j.imbio.2010.03.012
Peer Reviewed verified by ORBi

Baup, D., Fraga, L., Pernot, E., Van Acker, A., Vanherck, A.-S., Breckpot, K., Thielemans, K., Schurmans, S., Moser, M., & Leo, O. (2010). Variegation and silencing in a lentiviral-based murine transgenic model. Transgenic Research, 19, 399-414. doi:10.1007/s11248-009-9318-4
Peer Reviewed verified by ORBi

Baup, D., Moser, M., Schurmans, S., & Leo, O. (2009). Developmental regulation of the composite CAG promoter activity in the murine T lymphocyte cell lineage. Genesis, 47, 799-804. doi:10.1002/dvg.20569
Peer Reviewed verified by ORBi

Jacoby, M., Cox, J. J., Gayral, S., Hampshire, D. J., Ayub, M., Blockmans, M., Pernot, E., Kisseleva, M. V., Compère, P., Schiffmann, S. N., Gergely, F., Riley, J. H., Pérez-Morga, D., Woods, C. G., & Schurmans, S. (2009). INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse. Nature Genetics, 41, 1027-1031. doi:10.1038/ng.427
Peer Reviewed verified by ORBi

Cross, J. L., Meloni, B. P., Bakker, A. J., Sokolow, S., Herchuelz, A., Schurmans, S., & Knuckey, N. W. (2009). Neuronal injury in NCX3 knockout mice following permanent focal cerebral ischemia and in NCX3 knockout cortical neuronal cultures following oxygen-glucose deprivation and glutamate exposure. Journal of Experimental Stroke and Translational Medicine, 2 (1), 3-9.
Peer Reviewed verified by ORBi

Bielas, S. L., Silhavy, J. L., Brancati, F., Kisseleva, M. V., Al-Gazali, L., Sztriha, L., Bayoumi, R. A., Zaki, M. S., Abdel-Aleem, A., Rosti, O., Kayserili, H., Swistun, D., Scott, L. C., Bertini, E., Boltshauser, E., Fazzi, E., Travaglini, L., Field, S. J., Gayral, S., ... Gleeson, J. G. (2009). Mutations in the inositol polyphosphate-5-phosphatase E gene link phosphatidyl inositol signaling to the ciliopathies. Nature Genetics, 41, 1032-1036. doi:10.1038/ng.423
Peer Reviewed verified by ORBi

Molinaro, P., Cuomo, O., Pignataro, G., Boscia, F., Sirabella, R., Pannaccione, A., Secundo, A., Scorziello, A., Adornetto, A., Gala, R., Viggiona, D., Sokolow, S., Herchuelz, A., Schurmans, S., Di Renzo, G., & Annunziato, L. (2008). Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage. Journal of Neuroscience, 28, 1179-1184. doi:10.1523/JNEUROSCI.4671-07.2008
Peer Reviewed verified by ORBi

Jia, Y., Loison, F., Erneux, C., Park, S., Gao, C., Chai, L., Silberstein, L. E., Schurmans, S., & Luo, H. R. (2008). Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis. Proceedings of the National Academy of Sciences of the United States of America, 105, 4739-4744. doi:10.1073/pnas.0800218105
Peer Reviewed verified by ORBi

Jia, Y., Schurmans, S., & Luo, H. R. (2008). Regulation of innate immunity by inositol 1,3,4,5-tetrakisphosphate. Cell Cycle, 7, 2803-2808. doi:10.4161/cc.7.18.6688
Peer Reviewed verified by ORBi

Jeffs, G. J., Meloni, B., Sokolow, S., Herschuelz, A., Schurmans, S., & Knuckey, N. W. (2008). NCX3 knockout mice exhibit increased hippocampal CA1 and CA2 neuronal damage compared to wild-type mice following global cerebral ischemia. Experimental Neurology, 210, 268-273. doi:10.1016/j.expneurol.2007.10.013
Peer Reviewed verified by ORBi

Leyman, A., Pouillon, V., Bostan, A., Schurmans, S., Erneux, C., & Pesesse, X. (2007). The absence of expression of the three isoenzymes of inositol 1,4,5-trisphosphate 3-kinase does not prevent the formation of inositol pentakisphosphate and hexakisphosphate in mouse embryonic fibroblasts. Cellular Signalling, 19, 1497-1504. doi:10.1016/j.cellsig.2007.01.024
Peer Reviewed verified by ORBi

Maréchal, Y., Pesesse, X., Jia, Y., Pouillon, V., Pérez-Morga, D., Daniel, J., Izui, S., Cullen, P. J., Leo, O., Luo, H. R., Erneux, C., & Schurmans, S. (2007). Inositol 1,3,4,5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells. Proceedings of the National Academy of Sciences of the United States of America, 104, 13978-13983. doi:10.1073/pnas.0704312104
Peer Reviewed verified by ORBi

Jia, Y., Subramanian, K. K., Erneux, C., Pouillon, V., Hattori, H., Jo, H., You, J., Zhu, D., Serhan, C., Schurmans, S., & Luo, H. R. (2007). Ins(1,3,4,5)P4 negatively regulates PtdIns(3,4,5)P3 signaling in neutrophils. Immunity, 27, 453-467. doi:10.1016/j.immuni.2007.07.016
Peer Reviewed verified by ORBi

Blero, D., Payrastre, B., Schurmans, S., & Erneux, C. (2007). Phosphoinositide phosphatases in a network of signaling reactions. Pflügers Archiv: European Journal of Physiology, 455, 31-44. doi:10.1007/s00424-007-0304-5
Peer Reviewed verified by ORBi

Zhang, J., Liu, Z., Rasschaert, J., Blero, D., Deneubourg, L., Schurmans, S., Erneux, C., & Pesesse, X. (2007). SHIP2 controls PtdIns(3,4,5)P3 and PKB activity in response to oxidative stress. Cellular Signalling, 19, 2194-2200. doi:10.1016/j.cellsig.2007.06.022
Peer Reviewed verified by ORBi

Bearzatto, B., Servais, L., Roussel, C., Gall, D., Baba-Aïssa, F., Schurmans, S., de Kerchove d’Exaerde, A., Cheron, G., & Schiffmann, S. N. (2006). Targeted calretinin expression in granule cells of calretinin-null mice restores normal cerebellar functions. FASEB Journal, 20, 380-382. doi:10.1096/fj.05-3785fje
Peer Reviewed verified by ORBi

Blero, D., Zhang, J., Pesesse, X., Payrastre, B., Dumont, J. E., Schurmans, S., & Erneux, C. (2005). Phosphatidylinositol 3,4,5-trisphosphate modulation in Ship2-deficient mouse embryonic fibroblasts. FEBS Journal, 272, 2512-2522. doi:10.1111/j.1742-4658.2005.04672.x
Peer Reviewed verified by ORBi

Behrends, J., Clement, S., Pajak, B., Pohl, V., Maenhaut, C., Dumont, J. E., & Schurmans, S. (2005). Normal thyroid structure and function in rhophilin 2-deficient mice. Molecular and Cellular Biology, 25, 2846-2852. doi:10.1128/MCB.25.7.2846-2852.2005
Peer Reviewed verified by ORBi

Clément, S., Krause, U., Desmedt, F., Tanti, J. F., Behrends, J., Pesesse, X., Sasaki, T., Penninger, J., Doherty, M., Malaisse, W., Dumont, J. E., Le Marchand-Brustel, Y., Erneux, C., Hue, L., & Schurmans, S. (2004). Corrigenda: The lipid phosphatase SHIP2 controls insulin sensitivity. Nature, 431, 878. doi:10.1038/nature03003
Peer Reviewed verified by ORBi

Wang, Y., Keogh, R. J., Hunter, M. G., Mitchell, C. A., Frey, R. S., Javaid, K., Malik, A. B., Schurmans, S., Tridandapani, S., & Marsh, C. B. (2004). SHIP2 is recruited to the cell membrane upon M-CSF stimulation and regulates M-CSF-induced signaling. Journal of Immunology, 6820-6830. doi:10.4049/jimmunol.173.11.6820
Peer Reviewed verified by ORBi

Kaisaki, P. J., Delépine, M., Woon, P. Y., Sebag-Montefiore, L., Wilder, S. P., Menzel, S., Vionnet, N., Marion, E., Riveline, J. P., Charpentier, G., Schurmans, S., Levy, J. C., Lathrop, M., Farrall, M., & Gauguier, D. (2004). Polymorphisms in Type-II SH2 domain-containing Inositol 5-Phosphatase (INPPL1, SHIP2) are Associated with Physiological Abnormalities of the Metabolic Syndrome. Diabetes, 53, 1900-1904. doi:10.2337/diabetes.53.7.1900
Peer Reviewed verified by ORBi

Hascakova-Bartova, R., Pouillon, V., Dewaste, V., Moreau, C., Jacques, C., Banting, G., Schurmans, S., & Erneux, C. (2004). Identification and subcellular distribution of endogenous Ins(1,4,5)P3 3-kinase B in mouse tissues. Biochemical and Biophysical Research Communications, 323 (3), 920-925. doi:10.1016/j.bbrc.2004.08.152
Peer reviewed

Sokolow, S., Manto, M., Gailly, P., Molgó, J., Vandebrouck, C., Vanderwinden, J. M., Herchuelz, A., & Schurmans, S. (2004). Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3. Journal of Clinical Investigation, 113, 265-273. doi:10.1172/JCI18688
Peer Reviewed verified by ORBi

Pouillon, V., Hascakova-Bartova, R., Pajak, B., Adam, E., Bex, F., Dewaste, V., Van Lint, C., Leo, O., Erneux, C., & Schurmans, S. (2003). Inositol 1,3,4,5-tetrakisphosphate is essential for normal T lymphocyte development. Nature Immunology, 4, 1136-1143. doi:10.1038/ni980
Peer Reviewed verified by ORBi

Schurmans, S. (2003). SHIP2 et signalisation de l'insuline: quel role dans la pathogenese et le traitement du diabete de type 2? Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique, 158 (7-9), 335-9.
Peer Reviewed verified by ORBi

Giuriato, S., Pesesse, X., Bodin, S., Sasaki, T., Viala, C., Marion, E., Penninger, J., Schurmans, S., Erneux, C., & Payrastre, B. (2003). SH2 domain containing inositol 5-phosphatases 1 and 2 in blood platelets: interaction and respective role in the control of phosphatidylinositol 3,4,5-trisphosphate levels. Biochemical Journal, 376, 199-207. doi:10.1042/BJ20030581
Peer Reviewed verified by ORBi

Gall, D., Roussel, C., Susa, I., D’Angelo, E., Rossi, P., Bearzatto, B., Galas, M. C., Blum, D., Schurmans, S., & Schiffmann, S. N. (2003). Altered neuronal excitability in cerebellar granule cells of mice lacking calretinin. Journal of Neuroscience, 23 (28), 9320-9327. doi:10.1523/jneurosci.23-28-09320.2003
Peer Reviewed verified by ORBi

Robaye, B., Ghanem, E., Wilkin, F., Fokan, D., Van Driessche, W., Schurmans, S., Boeynaems, J. M., & Beauwens, R. (2003). Loss of nucleotide regulation of epithelial chloride transport in the jejunum of P2Y4-null mice. Molecular Pharmacology, 63 (4), 777-783. doi:10.1124/mol.63.4.777
Peer Reviewed verified by ORBi

Dremier, S., Coulonval, K., Perpete, S., Vandeput, F., Fortemaison, N., Van Keymeulen, A., Deleu, S., Ledent, C., Clement, S., Schurmans, S., Dumont, J. E., Lamy, F., Roger, P. P., & Maenhaut, C. (2002). The role of cyclic AMP and its effect on protein kinase A in the mitogenic action of thyrotropin on the thyroid cell. Annals of the New York Academy of Sciences, 968, 106-121. doi:10.1111/j.1749-6632.2002.tb04330.x
Peer Reviewed verified by ORBi

Marion, E., Kaisaki, P. J., Pouillon, V., Gueydan, C., Levy, J. C., Bodson, A., Krzentowski, G., Daubresse, J.-C., Mockel, J., Behrends, J., Servais, G., Szpirer, C., Kruys, V., Gauguier, D., & Schurmans, S. (2002). The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man. Diabetes, 51, 2012-2017. doi:10.2337/diabetes.51.7.2012
Peer Reviewed verified by ORBi

Clément, S., Krause, U., Desmedt, F., Tanti, J. F., Behrends, J., Pesesse, X., Sasaki, T., Penninger, J., Doherty, M., Malaisse, W., Dumont, J. E., Le Marchand-Bruste, Y., Erneux, C., Hue, L., & Schurmans, S. (2001). The lipid phosphatase SHIP2 controls insulin sensitivity. Nature, 409, 92-97. doi:10.1038/35051094
Peer Reviewed verified by ORBi

Clément, S., Refetoff, S., Robaye, B., Dumont, E., & Schurmans, S. (2001). Low TSH requirement and goiter in transgenic mice overexpressing IGF-1 and IGF-1R in the thyroid gland. Endocrinology, 142 (12), 5131-5139. doi:10.1210/endo.142.12.8534
Peer Reviewed verified by ORBi

Schurmans, S. (2001). The Insulin-Sensitive Side of SHIP2. Scientific World Journal, 1, 209-210. doi:10.1100/tsw.2001.34
Peer Reviewed verified by ORBi

Cheron, G., Schurmans, S., Lohof, A., d'Alcantara, P., Meyer, M., Draye, J.-P., Parmentier, M., & Schiffmann, S. N. (2000). Electrophysiological behavior of Purkinje cells and motor coordination in calretinin knock-out mice. Progress in Brain Research, 124, 299-308. doi:10.1016/s0079-6123(00)24024-7
Peer Reviewed verified by ORBi

Bouilleret, V., Schwaller, B., Schurmans, S., Celio, M. R., & Fritschy, J. M. (2000). Neurodegenerative and morphogenic changes in a mouse model of temporal lobe epilepsy do not depend on the expression of the calcium-binding proteins parvalbumin, calbindin, or calretinin. Neuroscience, 97 (1), 47-58. doi:10.1016/S0306-4522(00)00017-8
Peer Reviewed verified by ORBi

Schiffmann, S. N., Cheron, G., Lohoff, A., D’Alcantara, P., Meyer, M., Parmentier, M., & Schurmans, S. (1999). Impaired motor coordination and Purkinje cell excitability in mice lacking calretinin. Proceedings of the National Academy of Sciences of the United States of America, 96, 5257-5262. doi:10.1073/pnas.96.9.5257
Peer Reviewed verified by ORBi

Pirson, I., Behrens, J., Savonet, V., Goffard, J. C., Dumont, J. E., Schurmans, S., & MaenhauT, C. (1999). Identification and characterization of mRNAs differentially expressed in thyroid cells stimulated by a mitogenic treatment. Biochimie, 81, 309-314. doi:10.1016/S0300-9084(99)80075-3
Peer Reviewed verified by ORBi

Cocea, L., De Smet, A., Saghatchian, M., Fillatreau, S., Ferradini, L., Schurmans, S., Weill, J. C., & Reynaud, A. (1999). A targeted deletion of a region upstream from the Jkappa cluster impairs kappa chain rearrangement in cis in mice and in the 103/bcl2 cell line. Journal of Experimental Medicine, 189, 1443-1450. doi:10.1084/jem.189.9.1443
Peer Reviewed verified by ORBi

Schurmans, S., Carrio, R., Behrens, J., Pouillon, V., Merino, J., & Clément, S. (1999). The mouse SHIP2 (Inppl1) gene: complementary DNA, genomic structure, promoter analysis, and gene expression in the embryo and adult mouse. Genomics, 62, 260-271. doi:10.1006/geno.1999.5995
Peer Reviewed verified by ORBi

Coppée, F., Ledent, C., Clement, S., Dessars, B., Goffart, J. C., Parma, J., Parmentier, M., Schurmans, S., & Dumont, J. E. (1999). Transgenic models of thyroid tumorigenesis: relation to Chernobyl cancers. In G. Thomas, A. Karaoglou, ... E. D. Williams (Eds.), Radiation and Thyroid Cancer. Singapore: Word Scientific Publishing.

Gurden, H., Schiffmann, S. N., Lemaire, M., Böhme, G. A., ParmentieR, M., & Schurmans, S. (1998). Calretinin expression as a critical component in the control of dentate gyrus long-term potentiation in mice. European Journal of Neuroscience, 10, 3029-3033. doi:10.1111/j.1460-9568.1998.00373.x
Peer Reviewed verified by ORBi

Schurmans, S. (1998). Analysis of dentate gyrus long-term potentiation in calretinin mutant mice. Cell Biology International, 22 (5), 372-374.
Peer Reviewed verified by ORBi

Schiffman, S. N., Schurmans, S., Gurden, H., Lemaire, M., Lipp, H. P., Pochet, R., Imperato, A., Bohme, G. A., & Parmentier, M. (1998). Impaired LTP in the dentate gyrus of calretinin deficient mice. Cell Biology International, 22 (5), 386-387.
Peer Reviewed verified by ORBi

Halleux, P., Schurmans, S., Schiffmann, S. N., Lecocq, R., Conreur, J. L., Dumont, J. E., & Vanderhaeghen, J. J. (1998). Calcium binding protein calcyphosin in dog central astrocytes and ependymal cells and in peripheral neurons. Journal of Chemical Neuroanatomy, 15, 239-250. doi:10.1016/S0891-0618(98)00049-0
Peer Reviewed verified by ORBi

Vanderhaeghen, P., Schurmans, S., Vassart, G., & Parmentier, M. (1997). Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. Genomics, 39, 239-246. doi:10.1006/geno.1996.4490
Peer Reviewed verified by ORBi

Vanderhaeghen, P., Schurmans, S., Vassart, G., & Parmentier, M. (1997). Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome. Biochemical and Biophysical Research Communications, 237, 283-287. doi:10.1006/bbrc.1997.7043
Peer reviewed

Clément, S., Dumont, J., & Schurmans, S. (1997). Loss of calcyphosin gene expression in mouse and other rodents. Biochemical and Biophysical Research Communications, 232, 407-413. doi:10.1006/bbrc.1997.6297
Peer reviewed

Schurmans, S., Schiffmann, S. N., Gurden, H., Lemaire, M., Lipp, H. P., Schwam, V., Pochet, R., Imperato, A., Böme, G. A., & Parmentier, M. (1997). Impaired LTP induction in dentate gyrus of calretinin-deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 94, 10415-10420. doi:10.1073/pnas.94.19.10415
Peer Reviewed verified by ORBi

Gonzales, M., Schurmans, S., Ramos, A., Merino, R., Lambert, P. H., & Merino, J. (1995). CD4+ T cells determine the ability of spleen cells from F1 hybrid mice to induce neonatal tolerance to alloantigens and autoimmunity in parental mice. European Journal of Immunology, 25, 1760-1764.
Peer Reviewed verified by ORBi

Kramar, G., Schurmans, S., Berney, M., Izui, S., del Giudice, G., & Lambert, P. H. (1995). Autoimmunity following neonatal tolerance to alloantigens: role of donor I-A and I-E molecules. Journal of Autoimmunity, 8, 177-192. doi:10.1006/jaut.1995.0014
Peer Reviewed verified by ORBi

Parmentier, M., Schurmans, S., Libert, F., Vanderhaegen, P., & Vassart, G. (1994). Olfactory Receptors. In S. Peroutka (Ed.), Handbook of Receptors and Channels: G Protein Coupled Receptors (pp. 237-250). CRC Press, Boca Raton.

Schurmans, S., Gonzalez, A., Revilla, C., Ramos, A., Lambert, P. H., & Merino, J. (1994). Anti-LFA-1 (CD11a) monoclonal antibody interferes with the induction of neonatal tolerance to alloantigens. European Journal of Immunology, 24, 985-990. doi:10.1002/eji.1830240431
Peer Reviewed verified by ORBi

Parmentier, M., Vanderhaeghen, P., Schurmans, S., Libert, F., & Vassart, G. (1994). Génétique moléculaire des récepteurs olfactifs. MS. Medecine Sciences, 10, 1083-1090. doi:10.4267/10608/2531
Peer Reviewed verified by ORBi

Vanderhaeghen, P., Schurmans, S., Parmentier, M., & Vassart, G. (1994). Les spermatozoïdes ont-ils du nez ? MS. Medecine Sciences, 10, 1136-1140. doi:10.4267/10608/2537
Peer Reviewed verified by ORBi

Schurmans, S., Muscatelli, F., Miot, F., Mattei, M. G., Vassart, G., & Parmentier, M. (1993). The OLFR1 gene encoding the HGMP07E putative olfactory receptor maps to the 17p12-17p13 region of the human genome and reveals a MspI restriction fragment lenght polymorphism. CytoGenetics and Cell Genetics, 63, 200-204. doi:10.1159/000133534
Peer Reviewed verified by ORBi

Kramar, G., Schurmans, S., Aguado, T., Izui, S., del Guidice, G., & Lambert, P. H. (1993). Anti-Ia treatment prevents lupus-like autoimmune syndrome in mice neonatally tolerized to alloantigens. Journal of Autoimmunity, 1, 27-37. doi:10.1006/jaut.1993.1003
Peer Reviewed verified by ORBi

Parmentier, M., Libert, F., Perret, J., Eggerickx, D., Ledent, C., Schurmans, S., Raspe, E., Dumont, J., & Vassart, G. (1993). Cloning and characterization of G protein-coupled receptors. Advances in Second Messenger and Phosphoprotein Research, 28, 11-18.
Peer Reviewed verified by ORBi

Vanderhaeghen, P., Schurmans, S., Vassart, G., & Parmentier, M. (1993). Olfactory receptors are displayed on dog mature sperm cells. Journal of Cell Biology, 123, 1441-1452. doi:10.1083/jcb.123.6.1441
Peer Reviewed verified by ORBi

Parmentier, M., Libert, F., Schurmans, S., Schiffmann, S., Lefort, A., Eggerickx, D., Ledent, C., Mollereau, C., Gerard, C., Perret, J., Grootegoed, A., & Vassart, G. (1992). Expression of members of the putative olfactory receptor gene family in mammalian germ cells. Nature, 355, 453-455. doi:10.1038/355453a0
Peer Reviewed verified by ORBi

Vassart, G., Parmentier, M., Libert, M., Eggerickx, D., Gerard, C., Maenhaut, C., Mollereau, C., Perret, J., Schurmans, S., & Van Sande, J. (1992). Identification of orphan G protein-coupled receptors. Clinical Neuropharmacology, 15, 147-148. doi:10.1097/00002826-199201001-00079
Peer Reviewed verified by ORBi

Schurmans, S., Brighouse, G., Kramar, G., Wen, L., Izui, S., Merino, J., & Lambert, P. H. (1991). Transient T and B cell activation after neonatal induction of tolerance to MHC class II and Mls alloantigens. Journal of Immunology, 146, 2152-2160.
Peer Reviewed verified by ORBi

Schurmans, S., Merino, J., Qin, H., Kramar, G., Duchosal, M., Skalli, O., Benzonana, G., Gabbiani, G., & Lambert, P. H. (1991). Autoimmune syndrome after neonatal induction of tolerance to alloantigens: analysis of the specificity and of the cellular and genetic origin of autoantibodies. Autoimmunity, 9, 283-291. doi:10.3109/08916939108997130
Peer Reviewed verified by ORBi

Schurmans, S., Heusser, C., Qin, H., Merino, J., Brighouse, G., & Lambert, P. H. (1990). In vivo effects of anti-IL-4 monoclonal antibody on neonatal induction of tolerance and on an associated-autoimmune syndrome. Journal of Immunology, 145, 2465-2473.
Peer Reviewed verified by ORBi

Merino, J., Schurmans, S., Wen, L., Brighouse, G., Luzuy, S., & Lambert, P. H. (1990). Autoimmune syndrome after neonatal induction of tolerance to alloantigens: analysis of the role of donor T cells in the induction of autoimmunity. Clinical and Experimental Immunology, 79, 273-278. doi:10.1111/j.1365-2249.1990.tb05190.x
Peer Reviewed verified by ORBi

Reininger, L., Shibata, T., Schurmans, S., Merino, R., Lacour, M., & Izui, S. (1990). Spontaneous production of anti-mouse red blood cell autoantibodies is independent of the polyclonal activation in NZB mice. European Journal of Immunology, 20, 2405-2410. doi:10.1002/eji.1830201107
Peer Reviewed verified by ORBi

Merino, J., Schurmans, S., Duchosal, M., Izui, S., & Lambert, P. H. (1989). Autoimmune syndrome after induction of neonatal tolerance to alloantigens: CD4+ T cells from the tolerant host activate autoreactive F1 B cells. Journal of Immunology, 143, 2202-2208.
Peer Reviewed verified by ORBi

Merino, J., Qin, H., Schurmans, S., Gretener, D., Grau, G., & Lambert, P. H. (1989). Thrombocytopenia associated with the induction of neonatal tolerance to alloantigens: immunopathogenic mecanisms. European Journal of Immunology, 19, 1693-1699. doi:10.1002/eji.1830190925
Peer Reviewed verified by ORBi

Stott, D., Merino, J., Schurmans, S., & Lambert, P. H. (1988). Expression of anti-DNA clonotypes and the role of helper T-lymphocytes during the autoimmune response in mice tolerant to alloantigens. Autoimmunity, 1 (4), 253-266. doi:10.3109/08916938809010679
Peer Reviewed verified by ORBi

Stott, D., Merino, J., Schurmans, S., & Lambert, P. H. (1988). Analysis of the autoimmune response to DNA in tolerant mice by isoelectric focusing and reverse immunoblotting. 1: Clonal restriction and time course. Biochemical Society Transactions, 16, 147-148. doi:10.1042/bst0160147
Peer Reviewed verified by ORBi

Stott, D., Merino, J., Schurmans, S., & Lambert, P. H. (1988). Analysis of the autoimmune response to DNA in tolerant mice by isoelectric focusing and reverse immunoblotting. 2: The role of Helper T cells and major histocompatibility complex antigens. Biochemical Society Transactions, 16, 148-149.
Peer Reviewed verified by ORBi

Merino, J., Schurmans, S., Luzuy, S., Izui, S., Vassali, P., & Lambert, P. H. (1987). Autoimmune syndrome after induction of neonatal tolerance to alloantigens: effects of in vivo treatment with anti-T cell subset monoclonal antibodies. Journal of Immunology, 139, 1426-1431.
Peer Reviewed verified by ORBi

Contact ORBi