Profil

Sounni Nor Eddine

GIGA Cancer - Tumours and development biology

Département des sciences biomédicales et précliniques

Biologie cellulaire et moléculaire

See author's contact details
ORCID
0000-0001-9962-9236
Main Referenced Co-authors
Noël, Agnès  (120)
Cimino, Jonathan  (40)
Truong, Alice  (37)
Yip, Cassandre  (36)
Paye, Alexandra  (35)
Main Referenced Keywords
angiogenesis (10); Cancer (7); irradiation (7); MT4-MMP (7); cancer (6);
Main Referenced Unit & Research Centers
GIGA‐R - Giga‐Research - ULiège [BE] (5)
Giga-Cancer - ULiège [BE] (4)
1Laboratory of tumor and Developmental Biology, GIGA-CANCER, University of Liege, 4000, Liege, Belgium. 2Mass Spectrometry Laboratory, GIGA-R, Department of Chemistry, University of Liege, 4000, Liege, Belgium. (1)
GIGA Cardiovascular Sciences-Laboratory of Translational Research in Nephrology - ULiège [BE] (1)
GIGA-Cardiovascular (1)
Main Referenced Disciplines
Oncology (94)
Biochemistry, biophysics & molecular biology (37)
Human health sciences: Multidisciplinary, general & others (13)
Urology & nephrology (6)
Anatomy (cytology, histology, embryology...) & physiology (3)

Publications (total 156)

The most downloaded
3721 downloads
LAMBERT, V., Lecomte, J., Hansen, S., Blacher, S., Alvarez Gonzalez, M.-L., Struman, I., Sounni, N. E., Rozet, E., De Tullio, P., Foidart, J.-M., Rakic, J.-M., & Noël, A. (2013). Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice. Nature Protocols, 8 (11), 2197-2211. doi:10.1038/nprot.2013.135 https://hdl.handle.net/2268/158457

The most cited

279 citations (Scopus®)

LAMBERT, V., Lecomte, J., Hansen, S., Blacher, S., Alvarez Gonzalez, M.-L., Struman, I., Sounni, N. E., Rozet, E., De Tullio, P., Foidart, J.-M., Rakic, J.-M., & Noël, A. (2013). Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice. Nature Protocols, 8 (11), 2197-2211. doi:10.1038/nprot.2013.135 https://hdl.handle.net/2268/158457

Maja, M., Verfaillie, M., Van Der Smissen, P., Henriet, P., Pierreux, C. E., Sounni, N. E., & Tyteca, D. (10 January 2024). Targeting cholesterol impairs cell invasion of all breast cancer types. Cancer Cell International, 24 (1), 27. doi:10.1186/s12935-023-03206-z
Peer Reviewed verified by ORBi

Muñoz-Sáez, E., Moracho, N., Learte, A. I. R., Collignon, A., Arroyo, A. G., Noël, A., Sounni, N. E.* , & Sánchez-Camacho, C.*. (09 June 2023). Molecular Mechanisms Driven by MT4-MMP in Cancer Progression. International Journal of Molecular Sciences, 24 (12), 9944. doi:10.3390/ijms24129944
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* These authors have contributed equally to this work.

Sounni, N. E., & Sounni, N. E. (2023). Targeting lipid metabolism and ferroptosis: a promising therapeutic strategy for reversing breast cancer resistance [Paper presentation]. 2023 TELEVIE SEMINAR, Bruxelles, Belgium.

Azam, A., & Sounni, N. E. (19 December 2022). Lipid Metabolism Heterogeneity and Crosstalk with Mitochondria Functions Drive Breast Cancer Progression and Drug Resistance. Cancers, 14 (24), 6267. doi:10.3390/cancers14246267
Peer Reviewed verified by ORBi

Wery, C., Godfroid, A., Luis, G., Noël, A., Feron, O., & Sounni, N. E. (30 September 2022). Hypoxia regulates non-histone protein acetylation through SCD1 and PLIN2 in cancer cells to confer malignancy and drug resistance [Poster presentation]. Belgian Association for Cancer Research (BACR).

Wery, C., Luis, G., Godfroid, A., Noël, A., Feron, O., & Sounni, N. E. (06 September 2022). Hypoxia regulates non-histone proteins acetylation through PLIN2 and SCD1 in cancer cells [Poster presentation]. GIGA-DAY 2022.

Khbouz, B., LALLEMAND, F., Cirillo, A., Rowart, P., Legouis, D., Sounni, N. E., Noël, A., De Tullio, P., de Seigneux, S., & JOURET, F. (2022). Kidney-targeted irradiation triggers renal ischaemic preconditioning in mice. American Journal of Physiology. Renal Physiology. doi:10.1152/ajprenal.00005.2022
Peer Reviewed verified by ORBi

Rademaker, G.* , Boumahd, Y.* , Peiffer, R., Anania, S., Wissocq, T., Liégeois, M., Luis, G., Sounni, N. E., Agirman, F., Maloujahmoum, N., De Tullio, P., Thiry, M., Bellahcene, A., Castronovo, V., & Peulen, O. (July 2022). Myoferlin targeting triggers mitophagy and primes ferroptosis in pancreatic cancer cells. Redox Biology, 53, 102324. doi:10.1016/j.redox.2022.102324
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Wery, C., Godfroid, A., Luis, G., Noël, A., Feron, O., & Sounni, N. E. (22 June 2022). Hypoxia regulates acetylation/deacetylation of non-histone proteins through PLIN2 and SCD1 expression in cancer cells [Poster presentation]. European Association for Cancer Research.

Pottier, C., Montero-Ruiz, L., Noël, A., Jerusalem, G., & Sounni, N. E. (June 2022). Non genetic mechanisms of ER+ HER2- breast cancer resistance to the combination of Palbociclib and Fulvestrant [Poster presentation]. The European Association for Cancer Research Congress, Seville, Spain.
Editorial reviewed

Khbouz, B., Gu Shiyang, Lallemand, F., Rowart, P., POMA, L., Noël, A., Sounni, N. E., & JOURET, F. (22 April 2022). Characterization of the renal ischemic preconditioning induced by kidney-centered irradiation in mice [Paper presentation]. The fifth International Meeting on Ischemia Reperfusion Injuries in Transplantation (IMIRT) 2022, Poitiers, France.

Wery, C., Godfroid, A., Luis, G., Noël, A., Feron, O., & Sounni, N. E. (08 April 2022). Non-histone protein acetylation/deacetylation are regulated by PLIN2 and SCD1 during cancer cells adaptation to hypoxia [Paper presentation]. Télévie Seminar.

Wery, C., Luis, G., Godfroid, A., Noël, A., Feron, O., & Sounni, N. E. (05 April 2022). Hypoxia regulates acetylation/deacetylation of non-histone proteins through PLIN2 and SCD1 expression [Poster presentation]. The Cancer Metabolism Showcase and Workshop.

Wery, C., Godfroid, A., Luis, G., Noël, A., Feron, O., & Sounni, N. E. (14 December 2021). Cancer cells adaptation to hypoxia involves PLIN2 and SCD1 for non-histone protein acetylation/deacetylation [Poster presentation]. GIGA-Cancer Day.

Khbouz, B., Pinto Coelho, T., LALLEMAND, F., Rowart, P., POMA, L., Sounni, N. E., Noel, A., & JOURET, F. (08 December 2021). Le médicament anti-angiogénique Sunitinib contrarie le conditionnement ischémique rénal induit par l’irradiation [Poster presentation]. 21ème congrès de la Société Francophone de Transplantation (SFT), Genève, Switzerland.

Khbouz, B., LALLEMAND, F., ROWART, P., POMA, L., Sounni, N. E., Noël, A., & JOURET, F. (26 November 2021). Kidney-targeted radiotherapy triggers renal ischaemic preconditioning in mice [Paper presentation]. Autumn Meeting of BELGIAN SOCIETY OF PHYSIOLOGY AND PHARMACOLOGY, Bruxelles, Belgium.

Khbouz, B., LALLEMAND, F., Pasal, R., POMA, L., KRZESINSKI, J.-M., Sounni, N. E., Noël, A., & JOURET, F. (06 October 2021). Le médicament anti-angiogénique Sunitinib contrarie le conditionnement ischémique rénal induit par l’irradiation [Paper presentation]. 6ème congrès de la Société Francophone de Néphrologie Dialyse et Transplantation, Toulouse, France.

Khbouz, B., LALLEMAND, F., Rowart, P., POMA, L., KRZESINSKI, J.-M., Sounni, N. E., Noël, A., & JOURET, F. (30 August 2021). The irradiation-induced renal ischemic preconditioning is blunted by the oral administration of the anti-angiogenic agent, Sunitinib [Paper presentation]. The European Society for Organ Transplantation 2021, Milan, Italy.

Khbouz, B., LALLEMAND, F., Rowart, P., POMA, L., KRZESINSKI, J.-M., Sounni, N. E., Noël, A., & JOURET, F. (05 June 2021). Effect of renal irradiation in neo-angiogenesis and ischemic preconditioning [Paper presentation]. 58ème congrès de "The European Renal Association – European Dialysis and Transplant Association", Berlin, Germany.

Khbouz, B., LALLEMAND, F., Rowart, P., KRZESINSKI, J.-M., POMA, L., Sounni, N. E., Noël, A., & JOURET, F. (27 May 2021). The irradiation-induced renal ischemic preconditioning is blunted by the oral administration of the anti-angiogenic agent, Sunitinib [Poster presentation]. Annual meeting Belgian Society of Nephrology 2021.

Wery, C., Godfroid, A., Luis, G., Noël, A., Feron, O., & Sounni, N. E. (01 April 2021). Exploring mechanisms driven by lipid droplets and fatty-acid desaturase-1 in cancer progression [Paper presentation]. Télévie Seminar 2021.

Gallez, A., Blacher, S., Maquoi, E., Konradowski, E., Joiret, M., Primac, I., Gérard, C., Taziaux, M., Houtman, R., Geris, L., Lenfant, F., Marangoni, E., Sounni, N. E., Foidart, J.-M., Noël, A., & Pequeux, C. (2021). Estetrol combined to progestogen for menopause or contraception indication is neutral on breast cancer. Cancers. doi:10.3390/cancers13102486
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Luis, G.* , Godfroid, A.* , Nishiumi, S., Cimino, J., Blacher, S., Maquoi, E., Wery, C., Collignon, A., Longuespée, R., MONTERORUIZ, L., Dassoul, I., Maloujahmoum, N., Pottier, C., Mazzucchelli, G., De Pauw, E., Bellahcene, A., Yoshida, M., Noël, A., & Sounni, N. E. (2021). Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence. Redox Biology, 43, 102006. doi:10.1016/j.redox.2021.102006
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

POTTIER, C., Fresnais, M., Gilon, M., JERUSALEM, G., Longuespée, R.* , & Sounni, N. E.*. (2020). Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy. Cancers. doi:10.3390/cancers12030731
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Wery, C., Godfroid, A., LUIS, G., Noël, A., Feron, O., & Sounni, N. E. (07 February 2020). Role of Lipid droplets in cancer progression and resistance to anti-cancer drugs [Poster presentation]. Belgian Association for Cancer Research Annual Meeting.

Wery, C., Godfroid, A., Luis, G., Noël, A., Feron, O., & Sounni, N. E. (29 January 2020). Role of Lipid droplet in cancer progression and resistance to anti-cancer drugs [Poster presentation]. Télévie Seminar 2020.

Coussy, F., El-Botty, R., Château-Joubert, S., Dahmani, A., Montaudon, E., Leboucher, S., Morisset, L., Painsec, P., Sourd, L., Huguet, L., Nemati, F., Servely, J.-L., Larcher, T., Vacher, S., Briaux, A., Reyes, C., La Rosa, P., Lucotte, G., Popova, T., ... Marangoni, E. (2020). BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers. Science Translational Medicine, 12 (532). doi:10.1126/scitranslmed.aax2625
Peer Reviewed verified by ORBi

Wery, C., Godfroid, A., Luis, G., Noël, A., Feron, O., & Sounni, N. E. (25 October 2019). Role of lipid droplets in cancer cells in adaptation to hypoxia and tumor microenvironmental stresses [Paper presentation]. U-CRC Symposium.

Wery, C., Godfroid, A., LUIS, G., Noël, A., Feron, O., & Sounni, N. E. (06 September 2019). Role of cancer cells associated lipid droplets in adaptation to hypoxia and tumor microenvironmental stresses [Poster presentation]. EDT-Cancerology Annual Meeting 2019.

Primac, I., Maquoi, E., Blacher, S., Heljasvaara, R., Van Deun, J., Smeland, H. Y. H., Canale, A., Louis, T., Stuhr, L., Sounni, N. E., Cataldo, D., Pihlajaniemi, T., Pequeux, C., De Wever, O., Gullberg, D., & Noël, A. (09 July 2019). Stromal integrin alpha11 regulates PDGFR-beta signaling and promotes breast cancer progression. Journal of Clinical Investigation, 130. doi:10.1172/JCI125890
Peer Reviewed verified by ORBi

Yip, C., FOIDART, P., Noël, A., & Sounni, N. E. (16 January 2019). MT4-MMP: The GPI-Anchored Membrane-Type Matrix Metalloprotease with Multiple Functions in Diseases. International Journal of Molecular Sciences, 20 (2). doi:10.3390/ijms20020354
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FOIDART, P., Yip, C., Radermacher, J., Blacher, S., Lienard, M., MONTERORUIZ, L., Maquoi, E., Montaudon, E., Chateau-Joubert, S., COLLIGNON, J., Coibion, M., Jossa, V., Marangoni, E., Noël, A., Sounni, N. E.* , & JERUSALEM, G.*. (2019). Expression of MT4-MMP, EGFR, and RB in Triple-Negative Breast Cancer Strongly Sensitizes Tumors to Erlotinib and Palbociclib Combination Therapy. Clinical Cancer Research. doi:10.1158/1078-0432.CCR-18-1880
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Curtarello, M., Tognon, M., Venturoli, C., Silic-Benussi, M., Grassi, A., Verza, M., Minuzzo, S., Pinazza, M., Brillo, V., Tosi, G., Ferrazza, R., Guella, G., Iorio, E., Godfroid, A., Sounni, N. E., Amadori, A., & Stefano. (2019). Rewiring of Lipid Metabolism and Storage in Ovarian Cancer Cells after Anti-VEGF Therapy. Cells. doi:10.3390/cells8121601
Peer Reviewed verified by ORBi

Sounni, N. E. (15 October 2018). Metabolic adaptation to anti-angiogenic therapy [Paper presentation]. 8 ème Congrès de la société Française d'Angiogenes, Reims, France.

Sounni, N. E. (16 March 2018). Metabolic adaptation of tumor to hypoxia induced by anti-angiogenic therapy [Paper presentation]. International Workshop: Metabolic reprogramming as a target for Cancer and other Diseases, Malaga, Spain.

FOIDART, P., Yip, C., Radermacher, J., MONTERORUIZ, L., Coibion, M., Jossa, V., Marangoni, E., Noël, A., Sounni, N. E., & JERUSALEM, G. (24 February 2018). MT4-MMP, EGFR and RB expressions are predictive biomarkers of response to Erlotinib-Palbociclib combination in TNBC [Paper presentation]. Belgian Society of Medical Oncology: annual meeting, Ostende, Belgium.

Luis, G., Godfroid, A., Blacher, S., Noël, A., Sounni, N. E., Cimino, J. (Other coll.), Nishiumi, S. (Other coll.), & Yoshida, M. (Other coll.). (01 February 2018). Importance of fatty acid desaturation in tumor growth and oxidative stress response occurring during antiangiogenic treatment [Poster presentation]. Séminaire des chercheurs Télévie.

FOIDART, P., Yip, C., Radermacher, J., MONTERORUIZ, L., Marangoni, E., Noël, A., Sounni, N. E., JERUSALEM, G., Coibion, M., Jossa, V., & BLACHER, S. (27 January 2018). Expression of MT4-MMP, EGFR and Rb in triple negative breast cancers strongly sensitizes tumors to Erlotinib and Palbociclib combination therapy [Paper presentation]. Belgian Association for Cancer Research : Annual Meeting, Liège, Belgium.

Luis, G., Godfroid, A., Noël, A., Sounni, N. E., Cimino, J. (Other coll.), Nishiumi, S. (Other coll.), & Yoshida, M. (Other coll.). (27 January 2018). Stearoyl-CoA Desaturase-1 drives cancer malignancy via lipid desaturation and peroxidation after anti-angiogenic treatment withdrawal [Poster presentation]. Belgian Associaition for Cancer Research.

Marangoni, E., Laurent, C., Coussy, F., El Botty, R., Chateau-Joubert, S., Servely, J.-L., de Plater, L., Assayag, F., Dahmani, A., Montaudon, E., Nemati, F., Fleury, J., Vacher, S., Gentien, D., Rapinat, A., Foidart, P., Sounni, N. E., Noël, A., Salomon, A., ... Reyal, F. (2018). Capecitabine efficacy is correlated with TYMP and RB expression in PDX established from triple-negative breast cancers. Clinical Cancer Research. doi:10.1158/1078-0432.CCR-17-3490
Peer Reviewed verified by ORBi

Gérard, C., Hubeau, C., Carnet, O., Bellefroid, M., Sounni, N. E., Blacher, S., Bendavid, G., Moser, M., Fässler, R., Noël, A., Cataldo, D.* , & Rocks, N.*. (2018). Microenvironment-derived ADAM28 prevents cancer dissemination. Oncotarget, 9 (98), 37185-37199. doi:10.18632/oncotarget.26449
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Vandereyken, M., Jacques, S., Van Overmeire, E., Amand, M., Rocks, N., Delierneux, C., Singh, P., Singh, M., GHUYSEN, C., Wathieu, C., Zurashvili, T., Sounni, N. E., Moutschen, M., Gilles, C., Oury, C., Cataldo, D., Van Ginderachter, J. A., & Rahmouni, S. (2017). Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner. PLoS ONE. doi:10.1371/journal.pone.0185786
Peer Reviewed verified by ORBi

Primac, I., Blacher, S., cimino, J., Carnet, O., Liaudet-Coopman, E., de Wever, O., Sounni, N. E., Pequeux, C., Gullberg, D., & Noël, A. (24 April 2017). Cancer associated fibroblast-derived integrin α11 regulates PDGFRβ signaling to promote breast cancer progression [Paper presentation]. 7eme Congrès de la Société Française d’Angiogenèse, Toulouse, France.

Luis, G., Godfroid, A., Noël, A., Sounni, N. E., Cimino, J. (Other coll.), Shin, N. (Other coll.), & Yoshida, M. (Other coll.). (28 January 2017). Fatty acid desaturation promotes tumor growth and aggressiveness after hypoxia and oxygenation [Poster presentation]. Belgian Association for Cancer Research (BACR).

Sounni, N. E. (2017). Tumor host-interface in metastatic dissemination and adaptation to treatment [Paper presentation]. Medicinal Chemistry Drug Research Centre (CIRM) conferences, University of Liège, Liège, Belgium, Liège, Belgium.

Yip, C., Foidart, P., Somja, J., Truong, A., Lienard, M., Feyereisen, E., SCHROEDER, H., GOFFLOT, S., Donneau, A.-F., COLLIGNON, J., Delvenne, P., Sounni, N. E., Jerusalem, G., & Noël, A. (2017). MT4-MMP and EGFR expression levels are key biomarkers for breast cancer patient response to chemotherapy and erlotinib. British Journal of Cancer. doi:10.1038/bjc.2017.23
Peer Reviewed verified by ORBi

Luis, G., Godfroid, A., Noël, A., Sounni, N. E., Cimino, J. (Other coll.), Nishiumi, S. (Other coll.), & Yoshida, M. (Other coll.). (08 December 2016). Importance of fatty acid desaturation in tumor growth and oxidative stress response occurring during antiangiogenic treatment [Poster presentation]. Séminaire des chercheurs Télévie 2017.

Luis, G., Godfroid, A., Noël, A., Sounni, N. E., Cimino, J. (Other coll.), Nishiumi, S. (Other coll.), & Yoshida, M. (Other coll.). (27 October 2016). Fatty acid desaturation promotes tumor growth and aggressiveness after hypoxia and oxygenation [Poster presentation]. ISCAM.

Sounni, N. E. (20 October 2016). Metabolic adaptation to anti-angiogenic therapy, 3rd International Meeting on Cancer and Blood Vessels [Paper presentation]. 3rd International Meeting on Cancer and Blood Vessels.

Truong, A., Yip, C., PAYE, A., Blacher, S., Munaut, C., Deroanne, C., Noël, A., & Sounni, N. E. (February 2016). Dynamics of Internalization and Recycling of the Pro-Metastatic Membrane Type 4-Matrix Metalloproteinase (MT4-MMP) in Breast Cancer Cells. FEBS Journal, 283 (4), 704-22. doi:10.1111/febs.13625
Peer Reviewed verified by ORBi

Sounni, N. E. (2016). Lipid metabolism in cancer: energy source for survival or biomass building blocks [Paper presentation]. Lipid metabolism in cancer: energy source for survival or biomass building blocks, liège, Belgium.

Butler, G. S., Connor, A. R., Sounni, N. E., Eckhard, U., Morrison, C. J., Noël, A., & Overall, C. M. (2016). Degradomic and yeast 2-hybrid inactive catalytic domain substrate trapping identifies new membrane-type 1 matrix metalloproteinase (MMP14) substrates: CCN3 (Nov) and CCN5 (WISP2). Matrix Biology. doi:10.1016/j.matbio.2016.07.006
Peer Reviewed verified by ORBi

Cimino, J., Sounni, N. E., Quoirin, G., Blacher, S., De Pauw, E., & Fassotte-Noël, A. (03 December 2015). Role of Metabolic Reprogramming in Tumor Adaptation to Anti-angiogenic Therapy [Poster presentation]. Séminaire Televie 2015.

Yip, C., FOIDART, P., SOMJA, J., Truong, A., COLLIGNON, J., DELVENNE, P., Sounni, N. E., JERUSALEM, G., & Noël, A. (03 December 2015). MT4-MMP, a potential prognostic factor in triple negative breast cancer [Paper presentation]. Séminaire des chercheurs Télévie 2016, Gembloux, Belgium.

Sounni, N. E. (27 November 2015). Lipid metabolism in tumorigenesis and adaptation to cancer therapy [Paper presentation]. GIGA-Cancer seminar.

Truong, A., Yip, C., PAYE, A., Blacher, S., Munaut, C., Deroanne, C., Noël, A., & Sounni, N. E. (26 October 2015). Dynamics of Internalization and Recycling of the pro-Metastatic Membrane Type 4-Matrix Metalloproteinase (MT4-MMP) in Breast Cancer cells [Poster presentation]. Organelle Crosstalk in Membrane Dynamics and Cell Signalling, Edinburgh, United Kingdom.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., Jerusalem, G., Sounni, N. E., & Noël, A. (11 September 2015). Clinical significance of MT4-MMP and EGFR expression in Breast Cancer [Paper presentation]. EDT-Cancérologie Expérimentale Annual symposium « New advances in animal models in cancerology ».

Yip, C., FOIDART, P., SOMJA, J., Truong, A., COLLIGNON, J., DELVENNE, P., Sounni, N. E., JERUSALEM, G., & Noël, A. (September 2015). MT4-MMP, a potential therapeutic target in triple negative breast cancer [Poster presentation]. 2nd international society of cancer metabolism meeting - METABOLISM and MICROENVIRONMENT in CANCER PLASTICITY, Venise, Italy.

PAYE, A., Sounni, N. E., & Noël, A. (15 July 2015). Combination treatment of cancer.

Truong, A., Yip, C., PAYE, A., Munaut, C., Deroanne, C., Noël, A., & Sounni, N. E. (02 June 2015). Dynamics of Internalization and Recycling of the pro Metastatic Membrane Type 4-Matrix Metalloproteinase (MT4-MMP) in Breast Cancer cells [Poster presentation]. Biomedica : Life Science Summit.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (June 2015). Clinical significance of MT4-MMP and EGFR expression in Breast Cancer [Paper presentation]. Biomedica Life Science Summit, Genk, Belgium.

Cimino, J., Sounni, N. E., Fassotte-Noël, A., & De Pauw, E. (13 May 2015). Exploring Tumor lipid Heterogeneity by High-Resolution Mass Spectrometry Imaging [Poster presentation]. GIGA-CANCER DAY 2015.

Truong, A., Yip, C., PAYE, A., Munaut, C., Deroanne, C., Noël, A., & Sounni, N. E. (13 May 2015). Dynamics of Internalization and Recycling of the pro-Metastatic Membrane Type 4-Matrix Metalloproteinase (MT4-MMP) in Breast Cancer cells [Poster presentation]. GIGA Cancer Day 2015.

Cimino, J., Far, J., Debois, D., Blacher, S., Sounni, N. E., Fassotte-Noël, A., & De Pauw, E. (13 May 2015). Exploring Tumor lipid Heterogeneity by High-Resolution Mass Spectrometry Imaging [Paper presentation]. GIGA-CANCER DAY 2015.

Sounni, N. E. (12 May 2015). Deciphering mechanisms of cancer adaptation to targeted therapy [Paper presentation]. Joint Symposium of University of Liege and Kobe University, Kobe, Japan.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (11 February 2015). Clinical significance of MT4-MMP and EGFR expression in Breast Cancer [Paper presentation]. Séminaire des chercheurs Télévie 2015, Bruxelles, Belgium.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (31 January 2015). Clinical significance of MT4-MMP and EGFR expression in Breast Cancer [Paper presentation]. ABEC - Tumor Metabolism and Mitochondria, Bruxelles, Belgium.

Truong, A., PAYE, A., Yip, C., Munaut, C., Sounni, N. E., & Noël, A. (31 January 2015). Cell surface MT4-MMP is regulated through its internalization, degradation and recycling in breast cancer cells [Poster presentation]. BACR : Tumor metabolism and mitochondria.

Sounni, N. E. (31 January 2015). A shift towards lipid metabolism supports tumor adaptation to anti-angiogenic treatments and malignancy [Paper presentation]. ASSOCIATION BELGE POUR L'ETUDE DU CANCER A.B.E.C ANNUAL MEETING, Louvain-La-Neuve, Belgium.

Truong, A., PAYE, A., Yip, C., Munaut, C., Sounni, N. E., & Noël, A. (27 January 2015). Cell surface MT4-MMP is regulated through its internalization, degradation and recycling in breast cancer cells [Poster presentation]. GIGA DAY 2015.

Sounni, N. E. (15 January 2015). Cancer metabolism reprogramming in response to anti-angiogenic therapy [Poster presentation]. Keystone Symposia Conference J1: Integrating Metabolism and Tumor Biology, Vancouver, Canada.

Leroi, N., Sounni, N. E., Van Overmeire, E., Blacher, S., Marée, R., Van Ginderachter, J., Lallemand, F., LENAERTS, E., COUCKE, P., Noël, A.* , & MARTINIVE, P.*. (2015). The timing of surgery after neoadjuvant radiotherapy influences tumor dissemination in a preclinical model. Oncotarget. doi:10.18632/oncotarget.5931
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Paye, A., Truong, A., Yip, C., Cimino, J., Blacher, S., Munaut, C., Cataldo, D., Foidart, J.-M., Maquoi, E., COLLIGNON, J., Delvenne, P., Jerusalem, G., Noël, A.* , & Sounni, N. E.*. (October 2014). EGFR activation and signaling in cancer cells are enhanced by the membrane-bound metalloprotease MT4-MMP. Cancer Research, 74 (23), 6758-70. doi:10.1158/0008-5472.CAN-13-2994
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Cimino, J., Sounni, N. E., Blacher, S., Primac, I., Truong, A., Mazzucchelli, G., PAYE, A., Debois, D., De Tullio, P., De Pauw, E., & Fassotte-Noël, A. (30 September 2014). Blocking lipid synthesis overcomes tumor re-growth and metastasis after anti-angiogenic therapy withdrawal [Paper presentation]. EDT CANCER 2014.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (30 September 2014). Clinical significance of MT4-MMP and EGFR expression in Breast Cancer [Paper presentation]. Ecole Doctorale Thematique En Cancerologie Experimentale, Liege, Belgium.

Truong, A., PAYE, A., Yip, C., Munaut, C., Sounni, N. E., & Noël, A. (14 September 2014). Cell surface MT4-MMP is regulated through its internalization, degradation and recycling in breast cancer cells [Poster presentation]. EDT-Cancérologie Expérimentale : From Clinic to Lab and Vice Versa.

Cimino, J., Sounni, N. E., Debois, D., Truong, A., Quoirin, G., Blacher, S., De Tullio, P., De Pauw, E., & Fassotte-Noël, A. (19 May 2014). Tumor shift their metabolism to evade anti-angiogenic therapy. Poster presentation [Poster presentation]. GIGA-CANCER DAY.

Truong, A., PAYE, A., Yip, C., Munaut, C., Sounni, N. E., & Noël, A. (19 May 2014). Cell surface MT4-MMP is regulated through its internalization, degradation and recycling in breast cancer cells [Poster presentation]. GIGA Cancer Day 2014.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (19 May 2014). Clinical significance of MT4-MMP and EGFR expression in Breast Cancer [Paper presentation]. GIGA-Cancer Day 2014, Liege, Belgium.

Cimino, J., Sounni, N. E., Blacher, S., Primac, I., Truong, A., Mazzucchelli, G., PAYE, A., Debois, D., De Tullio, P., De Pauw, E., & Fassotte-Noël, A. (25 April 2014). Mechanisms of Tumor Adaptation to anti-angiogenic Receptor Tyrosine Kinase Inhibitors (RTKIs) [Poster presentation]. GIGA CANCER DAY 2014.

Cimino, J., Sounni, N. E., Debois, D., Truong, A., Blacher, S., De Tullio, P., De Pauw, E., & Fassotte-Noël, A. (29 January 2014). Cancer metabolism adaptation to Receptor Tyrosine Kinase (RTK) inhibition [Poster presentation]. GIGA DAY 2014.

Truong, A., PAYE, A., Yip, C., Munaut, C., Sounni, N. E., & Noël, A. (27 January 2014). Cell surface MT4-MMP is regulated through its internalization, degradation and recycling in breast cancer cells [Poster presentation]. GIGA DAY 2014.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (27 January 2014). Study of the pro-tumoral effects of MT4-MMP [Paper presentation]. GIGA-Day 2014, Liege, Belgium.

Sounni, N. E., Cimino, J., Blacher, S., Primac, I., Truong, A., Mazzucchelli, G., Paye, A., Calligaris, D., Debois, D., De Tullio, P., Mari, B., De Pauw, E., & Noël, A. (2014). Blocking lipid synthesis overcomes tumor re-growth and metastasis after anti-angiogenic therapy withdrawal. Cell Metabolism, 20 (2), 280-94. doi:10.1016/j.cmet.2014.05.022
Peer Reviewed verified by ORBi

Noël, A., & Sounni, N. E. (2014). MMP-Mediated Collagen Remodeling and Vessel Functions. In K. BRIX & W. STOCKER (Eds.), Proteases: Structure and Function (édition revue et corrigée, pp. 471-489). Springer-Verlag Wien 2014. doi:10.1007/978-3-7091-0885-7_14
Peer reviewed

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., Jerusalem, G., Sounni, N. E., & Noël, A. (05 December 2013). Study of the pro-tumoral effects of MT4-MMP [Paper presentation]. Séminaire des chercheurs Télévie 2014, Bruxelles, Belgium.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (13 September 2013). Study of the pro-tumoral effects of MT4-MMP [Paper presentation]. Annual Mini Symposium 2013, Liege, Belgium.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (02 July 2013). Regulation of breast cancer cell properties by MT4-MMP [Paper presentation]. Mini symposium "Tumor Microenvironment", Liege, Belgium.

Cimino, J., Far, J., Debois, D., Blacher, S., Sounni, N. E., Fassotte-Noël, A., & De Pauw, E. (08 June 2013). Towards Lipidomics of Low-Abundant Species by High-Resolution Mass Spectrometry [Poster presentation]. ASMS, American Society for Mass Spectrometry.

Cimino, J., Sounni, N. E., Debois, D., Blacher, S., De Tullio, P., De Pauw, E., & Fassotte-Noël, A. (17 May 2013). Mechanism of resistance to anti-angiogenic therapy [Poster presentation]. GIGA CANCER DAY 2013.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (17 May 2013). Regulation of breast cancer cell properties by MT4-MMP [Paper presentation]. GIGA-Cancer Day 2013.

Truong, A., PAYE, A., Yip, C., Munaut, C., Sounni, N. E., & Noël, A. (17 May 2013). Dynamics of MT4-MMP internalization and trafficking in breast cancer cells [Poster presentation]. GIGA Cancer Day 2013.

Cimino, J., Far, J., Debois, D., Blacher, S., Sounni, N. E., Fassotte-Noël, A., & De Pauw, E. (14 May 2013). Towards Lipidomics of Low-Abundant Species by High-Resolution Mass Spectrometry [Poster presentation]. Metabolomic seminar.

Cimino, J., Sounni, N. E., Debois, D., Blacher, S., De Tullio, P., De Pauw, E., & Fassotte-Noël, A. (13 May 2013). New mechanism of resistance to anti-angiogenic therapy [Paper presentation]. Metabolomic seminar.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (29 January 2013). Regulation of breast cancer cell properties by MT4-MMP [Paper presentation]. GIGA-Day 2013, Liege, Belgium.

Truong, A., PAYE, A., Yip, C., Munaut, C., Sounni, N. E., & Noël, A. (29 January 2013). MT4-MMP activity is regulated through its dimerization, internalization and degradation [Poster presentation]. JOURNEE SCIENTIFIQUE DES DOCTORANTS EN SCIENCES BIOMÉDICALES ET PHARMACEUTIQUES : New tools and strategies in the identification of pathology-related biomarkers.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (29 January 2013). Regulation of breast cancer cell properties by MT4-MMP [Paper presentation]. EDT cancérologie.

Truong, A., PAYE, A., Yip, C., Munaut, C., Sounni, N. E., & Noël, A. (28 January 2013). MT4-MMP activity is regulated through its dimerization, internalization and degradation [Poster presentation]. GIGA DAY 2013.

Cimino, J., Far, J., Debois, D., Blacher, S., Sounni, N. E., Fassotte-Noël, A., & De Pauw, E. (28 January 2013). Study of Low-Abundant Species by High-Resolution Mass Spectrometry [Poster presentation]. GIGA-DAY 2013.

Cimino, J., Far, J., Debois, D., Blacher, S., Sounni, N. E., Fassotte-Noël, A., & De Pauw, E. (25 January 2013). Towards Lipidomics of Low-Abundant Species by High-Resolution Mass Spectrometry [Poster presentation]. University of Mons, New tools and strategies in the identification of pathology-related biomarkers 2013, January 2013.

LAMBERT, V., Lecomte, J., Hansen, S., Blacher, S., Alvarez Gonzalez, M.-L., Struman, I., Sounni, N. E., Rozet, E., De Tullio, P., Foidart, J.-M., Rakic, J.-M., & Noël, A. (2013). Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice. Nature Protocols, 8 (11), 2197-2211. doi:10.1038/nprot.2013.135
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Cimino, J., Calligaris, D., Far, J., Debois, D., Blacher, S., Sounni, N. E., Noël, A., & De Pauw, E. (2013). Towards Lipidomics of Low-Abundant Species for Exploring Tumor Heterogeneity Guided by High-Resolution Mass Spectrometry Imaging. International Journal of Molecular Sciences, 14, 24560-24580. doi:10.3390/ijms141224560
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Delcombel, R., Janssen, L., Vassy, R., Gammons, M., Haddad, O., Richard, B., Letourneur, D., Bates, D., Hendricks, C., Waltenberger, J., Starzec, A., Sounni, N. E., Noël, A., Deroanne, C., Lambert, C., & Colige, A. (2013). New prospects in the roles of the C-terminal domains of VEGF-A and their cooperation for ligand binding, cellular signaling and vessels formation. Angiogenesis, 16 (2), 353-71. doi:10.1007/s10456-012-9320-y
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Detry, B., Blacher, S., Erpicum, C., Paupert, J., Maertens, L., Maillard, C., Munaut, C., Sounni, N. E., LAMBERT, V., Foidart, J.-M., Rakic, J.-M., Cataldo, D., & Noël, A. (2013). Sunitinib inhibits inflammatory corneal lymphangiogenesis. Investigative Ophthalmology and Visual Science, 54 (5), 3082-93. doi:10.1167/iovs.12-10856
Peer Reviewed verified by ORBi

Sounni, N. E., & Noël, A. (2013). Targeting the tumor microenvironment for cancer therapy. Clinical Chemistry, 59 (1), 85-93. doi:10.1373/clinchem.2012.185363
Peer Reviewed verified by ORBi

Cimino, J., Sounni, N. E., Calligaris, D., Debois, D., Truong, A., Blacher, S., De Tullio, P., De Pauw, E., & Noël, A. (10 December 2012). Séminaire des chercheurs Télévie 2013 [Poster presentation]. Séminaire des chercheurs Télévie 2013.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (10 December 2012). Regulation of breast cancer cell properties by MT4-MMP [Paper presentation]. Séminaire des chercheurs Télévie 2013, Liege, Belgium.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (09 November 2012). Regulation of breast cancer cell properties by MT4-MMP [Paper presentation]. Fall meeting of the belgian society for biochemistry and molecular biology - "Metabolomics... To Do What?", Namur, Belgium.

Cimino, J., Sounni, N. E., Calligaris, D., Debois, D., Noël, A., & De Pauw, E. (November 2012). Study of the molecular players and drastic changes in metabolic pathways of breast cancer adaptation to anti-angiogenic therapy with Molecular Imaging and quantitative proteomic approaches [Poster presentation]. Belgian Proteomics Association (BePA).

Cimino, J., Sounni, N. E., Calligaris, D., Debois, D., De Pauw, E., & Noël, A. (13 October 2012). Determination of the molecular players of adaptation to anti-angiogenic therapy in breast cancer by quantitative proteomic and high molecular MALDI Imaging [Poster presentation]. BSCDB meeting "EPIDERMAL CELL BIOLOGY", Namur, Belgium.

Yip, C., PAYE, A., Truong, A., Cimino, J., COLLIGNON, J., DELVENNE, P., JERUSALEM, G., Sounni, N. E., & Noël, A. (13 October 2012). Regulation of breast cancer cell properties by MT4-MMP [Paper presentation]. Fall meeting of the belgian society for cell and developmental biology - epidermal cell biology, Namur, Belgium.

Cimino, J., Calligaris, D., Debois, D., Sounni, N. E., Noël, A., & De Pauw, E. (04 September 2012). Study  of  breast  cancer  adaptation  to  anti-­angiogenic  therapies  by   molecular  imaging  on  tissue  slides [Paper presentation]. OurCon 2012 Ourense Conference on Imaging Mass Spectrometry, OurCon Spain, Spain.

Cimino, J., Sounni, N. E., Calligaris, D., Debois, D., De Pauw, E., & Noël, A. (22 June 2012). Molecular imaging through in combinaison with quantitative proteomic approaches unraveling the molecular players of breast cancer adaptation to anti-angiogenic therapy [Poster presentation]. GIGA-Cancer Day.

Cimino, J., Sounni, N. E., Calligaris, D., Debois, D., De Pauw, E., & Noël, A. (04 May 2012). Application of molecular imaging in combination with quantitative proteomic approaches to determine the molecular players of adaptation to anti-angiogenic therapy in breast cancer [Poster presentation]. GIGA-DAY, Liège, Belgium.

Sounni, N. E. (12 February 2012). Unexpected function of MT-MMP in cancer progression [Paper presentation]. Microenvimet_FP7-MEM final meeting, February 12, 2012, University of Liège, Liège, Belgium.

Noël, A., Gutierrez-Fernandez, A., Sounni, N. E., Behrendt, N., Maquoi, E., Lund, I., Cal, S., Hoyer-Hansen, G., & Lopez-Otin, C. (2012). New and Paradoxical Roles of Matrix Metalloproteinases in the Tumor Microenvironment. Frontiers in Pharmacology, 3 (140), 1. doi:10.3389/fphar.2012.00140
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Host, L., Paye, A., Detry, B., Blacher, S., Munaut, C., Foidart, J.-M., Seiki, M., Sounni, N. E.* , & Noël, A.*. (2012). The proteolytic activity of MT4-MMP is required for its proangiogenic and pro-metastatic promoting effects. International Journal of Cancer, 131 (7), 1537-1548. doi:10.1002/ijc.27436
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Detry, B., Blacher, S., Erpicum, C., Paupert, J., Maillard, C., Sounni, N. E., LAMBERT, V., & Noël, A. (October 2011). Inhibition of Experimental Corneal Neovascularization by Sunitinib Administration [Poster presentation]. 3ème congrés de la Société Française d'Angiogenèse.

Sounni, N. E., Paye, A., Host, L., & Noël, A. (13 May 2011). MT-MMPs as regulators of vessel stability associated with angiogenesis. Frontiers in Pharmacology, 2:111. doi:10.3389/fphar.2011.00111
Peer Reviewed verified by ORBi

Detry, B., Blacher, S., Erpicum, C., Paupert, J., Maillard, C., Sounni, N. E., & Noël, A. (05 February 2011). Inhibition of Pathological Lymph/angiogenesis by Sunitinib Administration [Poster presentation]. Annual meeting of the Association Belge pour l’Etude du Cancer, Liège, Belgium.

Delcombel, R., Janssen, L., Mineur, P., Sounni, N. E., Vassy, R., Richard, B., Noël, A., Deroanne, C., Colige, A., & Lambert, C. (2011). VEGF111, a diffusible and resistant-to-degradation variant of VEGF-A, induces the formation of a dense and characteristic network of small functional capillaries in vivo [Poster presentation]. 4th International Meeting on Angiogenesis, Amsterdam, Netherlands.

Masset, A., Maillard, C., Sounni, N. E., Jacobs, N., Bruyère, F., Delvenne, P., Tacke, M., Reinheckel, T., Foidart, J.-M., Coussens, L., & Noël, A. (2011). Unimpeded skin carcinogenesis in K14-HPV16 transgenic mice deficient for plasminogen activator inhibitor. International Journal of Cancer, 128 (2), 283-93. doi:10.1002/ijc.25326
Peer Reviewed verified by ORBi

Sounni, N. E. (2011). New function of MT4-MMP in cancer progression: angiogenesis and crosstalk with RTKs and Rb signaling pathways [Paper presentation]. Microenvimet, FP7_MEM, meeting. October 10, 2011, Biomedicum Helsinki, University of Helsinki, Finland.

Paupert, J., Sounni, N. E., & Noël, A. (2011). Lymphangiogenesis in post-natal tissue remodeling: Lymphatic endothelial cell connection with its environment. Molecular Aspects of Medicine, 32 (2), 146-158. doi:10.1016/j.mam.2011.04.002
Peer Reviewed verified by ORBi

Sounni, N. E., Dehne, K., van Kempen, L., Egeblad, M., Affara, N. I., Cuevas, I., Wiessen, J., Junankar, S., Kortes, L., Lee, J., Shen, J., Morrison, C. J., Overall, C. M., Krane, S. M., Werb, Z., Boudreau, N., & Coussens, L. M. (May 2010). Stromal regulation of vessel stability by MMP14 and TGFbeta. Disease Models and Mechanisms, 3, 317-332. doi:10.1242/dmm.003863
Peer Reviewed verified by ORBi

Sounni, N. E. (March 2010). MMPs and their inhibitors in vascular remodeling and vascular disease [Paper presentation]. GIGA Cancer Seminar, Marsh 12, 2010, CHU, University of Liège, Liège, Belgium.

Sounni, N. E., Rozanov, D. V., Remacle, A. G., Golubkov, V. S., Noël, A., & Strongin, A. Y. (2010). TIMP-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells. International Journal of Cancer, 126 (5), 1067-78. doi:10.1002/ijc.24690
Peer Reviewed verified by ORBi

Sounni, N. E. (29 May 2009). MMPs regulation of vascular permeability in cancer [Paper presentation]. GIGA Cancer, annual meeting, Friday 29 May 2009, CHU, University of Liège, Liège, Belgium.

Watkins, G. A., Jones, E. F., Scott Shell, M., VanBrocklin, H. F., Pan, M. H., Hanrahan, S. M., Feng, J. J., He, J., Sounni, N. E., Dill, K. A., Contag, C. H., Coussens, L. M., & Franc, B. L. (2009). Development of an optimized activatable MMP-14 targeted SPECT imaging probe. Bioorganic and Medicinal Chemistry, 15 (17), 653-9. doi:10.1016/j.bmc.2008.11.078
Peer Reviewed verified by ORBi

Radichev, I. A., Remacle, A. G., Sounni, N. E., Shiryaev, S. A., Rozanov, D. V., Zhu, W., Golubkova, N. V., Postnova, T. I., Golubkov, V. S., & Strongin, A. Y. (2009). Biochemical evidence of the interactions of membrane type-1 matrix metalloproteinase (MT1-MMP) with adenine nucleotide translocator (ANT): potential implications linking proteolysis with energy metabolism in cancer cells. Biochemical Journal, 420 (1), 37-47. doi:10.1042/BJ20090082
Peer Reviewed verified by ORBi

Chernov, A. V., Sounni, N. E., Remacle, A. G., & Strongin, A. Y. (2009). Epigenetic control of the invasion-promoting MT1-MMP/MMP-2/TIMP-2 axis in cancer cells. Journal of Biological Chemistry, 284 (19), 12727-34. doi:10.1074/jbc.M900273200
Peer Reviewed verified by ORBi

Sounni, N. E. (22 May 2007). Microenvironmental Regulation of Vascular Homeostasis and Leakage [Paper presentation]. Cancer Center, RIP meeting, May 22, 2007, Cancer Center, U.C.S.F. San Francisco. California, USA.

Sounni, N. E., Van Kempen, L., Dehne, K., Krane, S., & Cousens, L. (April 2007). Targeting TGFbeta Bioavailability to Regulate Vascular Stability and Leakage. FASEB Journal, 2007; 21:lb33.

Chabottaux, V., Sounni, N. E., Pennington, C. J., English, W. R., van den Brule, F., Blacher, S., Gilles, C., Munaut, C., Maquoi, E., Lopez-Otin, C., Murphy, G., Edwards, D. R., Foidart, J.-M., & Noël, A. (15 May 2006). Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases. Cancer Research, 66 (10), 5165-5172. doi:10.1158/0008-5472.CAN-05-3012
Peer Reviewed verified by ORBi

Sounni, N. E. (23 April 2006). Type-1 Collagen regulates vascular leakage by a Membrane Type-1 matrix Metalloproteinase- and TGFbeta-dependant mechanism [Paper presentation]. Pacific Coast Protease Workshop April 21-24, 2006, Palm spring, California, USA.

Sounni, N. E. (February 2005). Contribution of Membrane Type Matrix Metalloproteases in tumor progression [Paper presentation]. Seminar at Coussens's Lab, Cancer Center, University of California San Francisco, San Francisco California, USA.

Sounni, N. E., & Noël, A. (2005). Membrane type-matrix metalloproteinases and tumor progression. Biochimie, 87, 329-342. doi:10.1016/j.biochi.2004.07.012
Peer Reviewed verified by ORBi

Sounni, N. E. (January 2005). Membrane Type Matrix Metalloproreases in tumor angiogenesis [Paper presentation]. Seminar of the Institute of Pharmaceutical Sciences ETH, Zurich, January 2005, Switzeralnd.

Sounni, N. E. (2004). Rôle de la métalloprotéase membranaire-1 (MT1-MMP) dans l’invasion, la croissance et l’angiogenèse tumorales [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/162321

Maquoi, E., Sounni, N. E., Devy, L., Olivier, F., Frankenne, F., Krell, H. W., Grams, F., Foidart, J.-M., & Noël, A. (15 June 2004). Anti-invasive, antitumoral, and antiangiogenic efficacy of a pyrimidine-2,4,6-trione derivative, an orally active and selective matrix metalloproteinases inhibitor. Clinical Cancer Research, 10 (12, Pt 1), 4038-4047. doi:10.1158/1078-0432.CCR-04-0125
Peer Reviewed verified by ORBi

Noël, A., Maillard, C., Rocks, N., Jost, M., Chabottaux, V., Sounni, N. E., Maquoi, E., Cataldo, D., & Foidart, J.-M. (June 2004). Membrane associated proteases and their inhibitors in tumour angiogenesis. Journal of Clinical Pathology, 57 (6), 577-584. doi:10.1136/jcp.2003.014472
Peer Reviewed verified by ORBi

Sounni, N. E., Roghi, C., Chabottaux, V., Janssen, M., Munaut, C., Maquoi, E., Galvez, B. G., Gilles, C., Frankenne, F., Murphy, G., Foidart, J.-M., & Noël, A. (02 April 2004). Up-regulation of vascular endothelial growth factor-A by active membrane-type 1 matrix metalloproteinase through activation of Src-tyrosine kinases. Journal of Biological Chemistry, 279 (14), 13564-13574. doi:10.1074/jbc.M307688200
Peer Reviewed verified by ORBi

Lang, R., Braun, M., Sounni, N. E., Noël, A., Frankenne, F., Foidart, J.-M., Bode, W., & Maskos, K. (06 February 2004). Crystal structure of the catalytic domain of MMP-16/MT3-MMP: Characterization of MT-MMP specific features. Journal of Molecular Biology, 336 (1), 213-225. doi:10.1016/j.jmb.2003.12.022
Peer Reviewed verified by ORBi

Cataldo, D., Guéders, M., Rocks, N., Sounni, N. E., Evrard, B., Bartsch, P., Louis, R., Noël, A., & Foidart, J.-M. (September 2003). Pathogenic role of matrix metalloproteases and their inhibitors in asthma and chronic obstructive pulmonary disease and therapeutic relevance of matrix metalloproteases inhibitors. Cellular and Molecular Biology, 49 (6), 875-884.
Peer Reviewed verified by ORBi

Sounni, N. E. (17 May 2003). Specific up-regulation of VEGF-A by fully active MT1-MMP through activation of Src- tyrosine kinases [Paper presentation]. Belgian Society for Cell and Developmental Biology (BSCDB)- Meeting 16-17 May 2003-Brussels.

Sounni, N. E. (25 April 2003). Mechanisms of VEGF-A regulation by fully active MT1-MMP in Breast Cancer Cells [Paper presentation]. IAP meeting Ghent University , het Pand-Belgium.

Sounni, N. E., Janssen, M., Foidart, J.-M., & Noël, A. (March 2003). Membrane type-1 matrix metalloproteinase and TIMP-2 in tumor angiogenesis [letter to the editor]. Matrix Biology, 22 (1), 55-61. doi:10.1016/S0945-053X(03)00003-9
Peer Reviewed verified by ORBi

Sounni, N. E. (2003). Specific up-regulation of VEGF-A by fully active MT1-MMP through activation of Src- tyrosine kinases [Paper presentation]. 10th Euregional Oncology Meeting, May 2003, Maastricht.

Sounni, N. E., Devy, L., Hajitou, A., Frankenne, F., Munaut, C., Gilles, C., Deroanne, C., Thompson, E. W., Foidart, J.-M., & Noël, A. (April 2002). MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression. FASEB Journal, 16 (6), 555-564. doi:10.1096/fj.01-0790com
Peer Reviewed verified by ORBi

Sounni, N. E., Baramova, E., Munaut, C., Maquoi, E., Frankenne, F., Foidart, J.-M., & Noël, A. (01 March 2002). Expression of membrane type 1 matrix metalloproteinase (MT1-MMP) in A2058 melanoma cells is associated with MMP-2 activation and increased tumor growth and vascularization. International Journal of Cancer, 98 (1), 23-28. doi:10.1002/ijc.10134
Peer Reviewed verified by ORBi

Sounni, N. E. (2002). MT1-MMP expression promotes tumor growth and angiogenesis through an up- regulation of vascular endothelial growth factor expression [Paper presentation]. Belgian Association for Cancer Research, Brussels-Belgium.

Sounni, N. E. (19 April 2001). MT1-MMP expression promotes tumor growth and angiogenesis [Paper presentation]. 8th Euregional Oncology Meeting, Maastricht.

Hajitou, A., Sounni, N. E., Devy, L., Grignet, C., Lewalle, J.-M., Li, H., Deroanne, C., Lu, H., Colige, A., Nusgens, B., Frankenne, F., Maron, A., Yeh, P., Perricaudet, M., Chang, Y., Soria, C., Calberg-Bacq, C.-M., Foidart, J.-M., & Noël, A. (15 April 2001). Down-Regulation of Vascular Endothelial Growth Factor by Tissue Inhibitor of Metalloproteinase-2: Effect on in Vivo Mammary Tumor Growth and Angiogenesis. Cancer Research, 61 (8), 3450-7.
Peer Reviewed verified by ORBi

Noël, A., Albert, V., Bajou, K., Bisson, C., Devy, L., Frankenne, F., Maquoi, E., Masson, V., Sounni, N. E., & Foidart, J.-M. (April 2001). New Functions of Stromal Proteases and Their Inhibitors in Tumor Progression. Surgical Oncology Clinics of North America, 10 (2), 417-32. doi:10.1016/s1055-3207(18)30073-5
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Maquoi, E., Frankenne, F., Baramova, E., Munaut, C., Sounni, N. E., Remacle, A., Noël, A., Murphy, G., & Foidart, J.-M. (14 April 2000). Membrane Type 1 Matrix Metalloproteinase-Associated Degradation of Tissue Inhibitor of Metalloproteinase 2 in Human Tumor Cell Lines. Journal of Biological Chemistry, 275 (15), 11368-78. doi:10.1074/jbc.275.15.11368
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Frankenne, F., Noël, A., Bajou, K., Sounni, N. E., Goffin, F., Masson, V., Munaut, C., Remacle, A., & Foidart, J.-M. (September 1999). Molecular interactions involving urokinase plasminogen activator (uPA), its receptor (uPAR) and its inhibitor, plasminogen activator inhibitor-1 (PAI-1), as new targets for tumour therapy. Expert Opinion on Therapeutic Targets, 3 (3), 469-481 (13. doi:10.1517/14728222.3.3.469
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