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Gianfrancesco Marco

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Main Referenced Co-authors
Paquot, Nicolas  (18)
Legrand, Sylvie  (11)
Piette, Jacques  (11)
Dehairs, Jonas (9)
Rodriguez, Julie (7)
Main Referenced Keywords
Obesity (5); obesity (3); free fatty acids (2); Gut microbiota (2); gut microbiota (2);
Main Referenced Unit & Research Centers
GIGA-I3 - Giga-Infection, Immunity and Inflammation - ULiège [BE] (1)
Main Referenced Disciplines
Endocrinology, metabolism & nutrition (9)
Biochemistry, biophysics & molecular biology (6)
Human health sciences: Multidisciplinary, general & others (2)
Immunology & infectious disease (1)
Laboratory medicine & medical technology (1)

Publications (total 19)

The most downloaded
1059 downloads
Gianfrancesco, M., Paquot, N., Piette, J., & Legrand, S. (2018). Lipid bilayer stress in obesity-linked inflammatory and metabolic disorders. Biochemical Pharmacology. doi:10.1016/j.bcp.2018.02.022 https://hdl.handle.net/2268/223918

The most cited

144 citations (Scopus®)

Rodriguez, J., Hiel, S., Neyrinck, A. M., Le Roy, T., Pötgens, S. A., Leyrolle, Q., Pachikian, B. D., Gianfrancesco, M., Cani, P. D., Paquot, N., Cnop, M., Lanthier, N., Thissen, J.-P., Bindels, L. B., & Delzenne, N. M. (2020). Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients. Gut. doi:10.1136/gutjnl-2019-319726 https://hdl.handle.net/2268/250072

Rodriguez, J., Neyrinck, A. M., Van Kerckhoven, M., Gianfrancesco, M., Renguet, E., Bertrand, L., Cani, P. D., Lanthier, N., Cnop, M., Paquot, N., Thissen, J.-P., Bindels, L. B., & Delzenne, N. M. (2022). Physical activity enhances the improvement of body mass index and metabolism by inulin: a multicenter randomized placebo-controlled trial performed in obese individuals. BMC Medicine, 20 (1), 110. doi:10.1186/s12916-022-02299-z
Peer Reviewed verified by ORBi

Wilkin, C., Colonval, M., Dehairs, J., Esser, N., Iovino, M., Gianfrancesco, M., FADEUR, M., Swinnen, J. V., PAQUOT, N., Piette, J., & Legrand, S. (01 September 2021). Modulation of the phospholipidome in circulating immune cells of obese patients are associated to insulin resistance or glycemic status [Poster presentation]. 6th European Congress of Immunology.

Leyrolle, Q., Cserjesi, R., Mulders, M. D., Zamariola, G., Hiel, S., Gianfrancesco, M., Portheault, D., amadieu, C., Bindels, L. B., Leclercq, S., Rodriguez, J., Neyrinck, A. M., Cani, P. D., Lanthier, N., Trefois, P., Bindelle, J., PAQUOT, N., Cnop, M., Thissen, J.-P., ... Delzenne, N. (2021). Prebiotic effect on mood in obese patients is determined by the initial gut microbiota composition: A randomized, controlled trial. Brain, Behavior and Immunity, 94, 289-298. doi:10.1016/j.bbi.2021.01.014
Peer Reviewed verified by ORBi

LEYROLLE, Q., Cserjesi, R., Mulders, M., Zamariola, G., Hiel, S., Gianfrancesco, M., Rodriguez, J., Paquot, N., & DELZENNE, N. (2021). Specific gut microbial, biological, and psychiatric profiling related to binge eating disorders: A cross-sectional study in obese patients. Clinical Nutrition. doi:10.1016/j.clnu.2020.09.025
Peer Reviewed verified by ORBi

Hiel, S.* , Gianfrancesco, M.* , Rodriguez, J.* , Portheault, D., Leyrolle, Q., Bindels, L. B., Gomes da Silveira Cauduro, C., Mulders, M. D. G. H., Zamariola, G., Azzi, A.-S., Kalala, G., Pachikian, B. D., Amadieu, C., Neyrinck, A. M., Loumaye, A., Cani, P. D., Lanthier, N., Trefois, P., Klein, O., ... Delzenne, N. M. (2020). Link between gut microbiota and health outcomes in inulin -treated obese patients: Lessons from the Food4Gut multicenter randomized placebo-controlled trial. Clinical nutrition (Edinburgh, Scotland). doi:10.1016/j.clnu.2020.04.005
Peer reviewed
* These authors have contributed equally to this work.

Rodriguez, J., Hiel, S., Neyrinck, A. M., Le Roy, T., Pötgens, S. A., Leyrolle, Q., Pachikian, B. D., Gianfrancesco, M., Cani, P. D., Paquot, N., Cnop, M., Lanthier, N., Thissen, J.-P., Bindels, L. B., & Delzenne, N. M. (2020). Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients. Gut. doi:10.1136/gutjnl-2019-319726
Peer Reviewed verified by ORBi

Gianfrancesco, M. (2019). FREE FATTY ACIDS AS MODULATORS OF THE NLRP3 INFLAMMASOME IN HUMAN MACROPHAGES ROLE IN OBESITY/TYPE 2 DIABETES [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/314927

Gianfrancesco, M., Dehairs, J., L'homme, L., Herinckxe, G., Esser, N., Jansen, O., Habraken, Y., Lassence, C., Swinnen, J., Rider, M., Piette, J., PAQUOT, N., & Legrand, S. (April 2019). Saturated fatty acids induce NLRP3 activation in human macrophages through K+ efflux resulting from phospholipid saturation and Na, K-ATPase disruption. BBA - Molecular and Cell Biology of Lipids, 1864, 1017–1030. doi:10.1016/j.bbalip.2019.04.001
Peer reviewed

Colonval, M., Gouasmia, H., Fettweiss, G., Gianfrancesco, M., Dehairs, J., PAQUOT, N., Swinnen, J., Piette, J., & Legrand, S. (25 June 2018). Saturated fatty acid-treated human macrophages and obese adipose tissue macrophages exhibit similar metabolic reprogramming [Poster presentation]. Cell Symposium: Translational Immunometabolism.

Gianfrancesco, M., Paquot, N., Piette, J., & Legrand, S. (2018). Lipid bilayer stress in obesity-linked inflammatory and metabolic disorders. Biochemical Pharmacology. doi:10.1016/j.bcp.2018.02.022
Peer Reviewed verified by ORBi

Gianfrancesco, M., Dehairs, J., L’homme, L., Herinckx, G., Bloch, K., Piette, J., Rider, M., Swinnen, J., Paquot, N., Esser, N., & Legrand, S. (2018). La saturation des phospholipides membranaires induit un efflux de K+ et une activation de l’inflammasome NLRP3 dans des macrophages humains via l’intermédiaire de la Na, K-ATPase. Nutrition Clinique et Metabolisme, 32 (1), 38. doi:10.1016/j.nupar.2017.11.006
Peer Reviewed verified by ORBi

Hiel, S., Rodriguez, J., Gianfrancesco, M., Portheault, D., Kalala, G., Neyrinck, A. M., Pachikian, B., Potgëns, S., Bindels, L., Lanthier, N., Trefois, P., Bindelle, J., Paquot, N., Cnop, M., Thissen, J.-P., & Delzenne, N. M. (September 2017). Dietary inulin supplementation promotes weight loss in obese individuals [Poster presentation]. 39th annual congress of European society for clinical nutrition and metabolism (ESPEN 2017), The Hague, Netherlands.

Gianfrancesco, M., Dehairs, J., Bloch, K., L’homme, L., Jansen, O., Frederich, M., Piette, J., Swinnen, J., Paquot, N., Esser, N., & Legrand, S. (2017). Implication du remodelage de la membrane plasmique par les acides gras dans la régulation de l’activité de l’inflammasome NLRP3 dans des macrophages humains. Nutrition Clinique et Metabolisme, 31 (3), 255. doi:10.1016/j.nupar.2017.06.002
Peer Reviewed verified by ORBi

Gianfrancesco, M., Dehairs, J., L'Homme, L., Colonval, M., Piette, J., Swinnen, J., Paquot, N., Esser, N., & Legrand, S. (2017). The saturation of membrane phospholipids would be a trigger for K+ efflux and NLRP3 inflammasome activation in human monocytes/macrophages. Diabetologia.
Peer Reviewed verified by ORBi

Hiel, S., Rodriguez, J., Gianfrancesco, M., Portheault, D., Kalala Bolokango, G., Neyrinck, A., Pachikian, B., Pötgens, S., Bindels, L., Bindelle, J., Paquot, N., Cnop, M., Thissen, J.-P., & Delzenne, N. (2017). Interest of profiling the gut microbiota to evaluate the effect of dietary inulin on obesity-related metabolic disorders in humans: the FOOD4GUT intervention study. Clinical Nutrition, 36, 273-S274. doi:10.1016/S0261-5614(17)30830-0
Peer Reviewed verified by ORBi

Gianfrancesco, M., Dehairs, J., Bloch, K., L'Homme, L., Piette, J., Swinnen, J., Paquot, N., Esser, N., & Legrand, S. (12 September 2016). Involvement of membrane remodelling induced by fatty acids in the regulation of the NLRP3 inflammasome activity in human macrophages [Poster presentation]. 52nd Annual Meeting of the European Association for the Study od Diabetes, Munich, Germany.

Gianfrancesco, M., Dehairs, J., Bloch, K., L'homme, L., Piette, J., Swinnen, J., Paquot, N., Esser, N., & Legrand, S. (August 2016). Involvement of membrane remodelling induced by fatty acids in the regulation of the NLRP3 inflammasome activity in human macrophages. Diabetologia, 59 (Supplement 1), 291.
Peer Reviewed verified by ORBi

Gianfrancesco, M., Bloch, K., Dehairs, J., L'Homme, L., Swinnen, J., Piette, J., SCHEEN, A., Paquot, N., Legrand-Poels, S., & ESSER, N. (March 2016). Implication du remodelage membranaire induit par les acides gras dans la régulation de l’activité de l’inflammasome NLRP3 dans les macrophages humains [Paper presentation]. Congrès 2016 de la Société Francophone du Diabète, Lyon, France.

Gianfrancesco, M., Bloch, K., Dehairs, J., L'Homme, L., Swinnen, J., Piette, J., PAQUOT, N., ESSER, N., & Legrand-Poels, S. (September 2015). Deciphering the molecular mechanisms underlying NLRP3 inflammasome activation by saturated fatty acids [Poster presentation]. 3rd International Conference on Immunometabolism: Molecular and Cellular Immunology of Metabolism, Chania, Greece.

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