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Penning Sophie

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Main Referenced Co-authors
Desaive, Thomas  (57)
Chase, J. Geoffrey (45)
Shaw, Geoffrey M. (31)
Preiser, Jean-Charles  (30)
Le Compte, Aaron (20)
Main Referenced Keywords
Biomedical system modelling (2); Glycemic control (2); Glycemic variability (2); Intensive care units (2); Organ Failure (2);
Main Referenced Disciplines
Engineering, computing & technology: Multidisciplinary, general & others (51)
Anesthesia & intensive care (8)
Cardiovascular & respiratory systems (1)
Endocrinology, metabolism & nutrition (1)

Publications (total 60)

The most downloaded
87301 downloads
Penning, S., & MASSION, P. (16 March 2012). Le contrôle de la glycémie [Paper presentation]. Festival ImagéSanté. https://hdl.handle.net/2268/123390

The most cited

107 citations (Scopus®)

Fisk, L. M., Le Compte, A. J., Shaw, G. M., Penning, S., Desaive, T., & Chase, J. G. (2012). STAR Development and Protocol Comparison. IEEE Transactions on Biomedical Engineering. doi:10.1109/TBME.2012.2214384 https://hdl.handle.net/2268/130690

Penning, S. (2014). Tight Glycaemic Control - Model-based methods to answer critical questions about this controversial therapy [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/171897

Penning, S., Pironet, A., Chase, J. G., Pretty, C., & Desaive, T. (2014). Survey about diffusion and adoption of glycaemic controller in European intensive care units. In Proceedings of the 19th IFAC Conference.
Peer reviewed

Sah Pri, A., Chase, J. G., Pretty, C., Shaw, G. M., PREISER, J.-C., Penning, S., Desaive, T., & Taccone, F. (2014). Insulin Sensitivity Variability during Hypothermia. In Proceedings of the 19th IFAC Conference.
Peer reviewed

Penning, S., LAMBERMONT, B., Desaive, T., Pretty, C. G., & Chase, J. G. (August 2014). In silico assessment of a computerized model-based glycaemic control approach in a Belgian medical intensive care unit [Poster presentation]. 19th World Congress of the International Federation of Automatic Control, Cape Town, South Africa.

Penning, S., LAMBERMONT, B., Desaive, T., Pretty, C., & Chase, J. G. (2014). In silico assessment of a computerized model-based glycaemic control approach in a Belgian medical intensive care unit. In Proceedings of the 19th IFAC Conference.
Peer reviewed

Penning, S., Pironet, A., Chase, J. G., Pretty, C. G., & Desaive, T. (August 2014). Survey about diffusion and adoption of glycaemic controller in European intensive care units [Paper presentation]. 19th World Congress of the International Federation of Automatic Control, Cape Town, South Africa.

Penning, S., Chase, J. G., PREISER, J.-C., Pretty, C. G., Signal, M., Mélot, C., & Desaive, T. (2014). Does the achievement of an intermediate glycemic target reduce organ failure and mortality? A post-hoc analysis of the Glucontrol Trial. Journal of Critical Care. doi:10.1016/j.jcrc.2014.01.013
Peer Reviewed verified by ORBi

Pretty, C. G., Le Compte, A., Penning, S., Fisk, L., Shaw, G. M., Desaive, T., & Chase, J. G. (2014). Interstitial insulin kinetic parameters for a 2-compartment insulin model with saturable clearance. Computer Methods and Programs in Biomedicine. doi:10.1016/j.cmpb.2014.01.011
Peer Reviewed verified by ORBi

Sah Pri, A., Chase, J. G., Pretty, C. G., Shaw, G. M., PREISER, J.-C., Vincent, J.-L., Oddo, M., Taccone, F. S., Penning, S., & Desaive, T. (2014). Evolution of insulin sensitivity and its variability in out of hospital cardiac arrest (OHCA) patients treated with hypothermia. Critical Care, 18 (5), 586. doi:10.1186/s13054-014-0586-x
Peer Reviewed verified by ORBi

Pironet, A., & Penning, S. (2013). Calculez l'âge de vos artères. (ULiège - Université de Liège).

Pretty, C., Signal, M., Fisk, L., Penning, S., Le Compte, A., Shaw, G. M., Desaive, T., & Chase, J. G. (2013). Impact of sensor and measurement timing errors on model-based insulin sensitivity. Computer Methods and Programs in Biomedicine. doi:10.1016/j.cmpb.2013.08.007
Peer Reviewed verified by ORBi

Sah Pri, A., Chase, J. G., Le Compte, A. J., Shaw, G. M., PREISER, J.-C., Taccone, F., Penning, S., & Desaive, T. (September 2013). Insulin Sensitivity during Hypothermia in Critically Ill Patients [Poster presentation]. The fifth International Conference on Computational Bioengineering, Leuven, Belgium.

Penning, S., MASSION, P., Pretty, C., Desaive, T., & Chase, J. G. (December 2012). Insulin clearance during hyper-insulinemia euglycemia therapy [Poster presentation]. 11th Belgian National Day on Biomedical Engineering, Bruxelles, Belgium.

Pretty, C., Penning, S., Le Compte, A. J., Fisk, L., Benyo, B., Chase, J. G., & Desaive, T. (December 2012). Model-based glycemic control in critical care [Poster presentation]. 11th Belgian National Day on Biomedical Engineering, Bruxelles, Belgium.

Penning, S., MASSION, P., Pretty, C., Desaive, T., & Chase, J. G. (2012). Insulin clearance during hyper-insulinemia euglycemia therapy. In Proceedings of the 11th Belgian Day on Biomedical Engineering.
Peer reviewed

Pretty, C., Penning, S., Le Compte, A. J., Fisk, L., Benyó, B., Chase, & Desaive, T. (2012). Model-based glycemic control in critical care. In Proceedings of the 11th Belgian Day on Biomedical Engineering.
Peer reviewed

Penning, S., Signal, M., PREISER, J.-C., Shaw, G. M., Le Compte, A. J., Pretty, C., Desaive, T., & Chase, J. G. (15 October 2012). Cumulative time in band (cTIB): glycemic level, variability and patient outcome all in one [Paper presentation]. 25th annuel congress of ESICM, Lisbon, Portugal.

Penning, S., Signal, M., PREISER, J.-C., Shaw, G. M., Le Compte, A. J., Pretty, C., Desaive, T., & Chase, J. G. (October 2012). Cumulative Time in Band (cTIB): Glycemic Level, Variability and Patient Outcome All in 1. Intensive Care Medicine, 38 (Suppl 1), 121.
Peer Reviewed verified by ORBi

Penning, S., Signal, M., PREISER, J.-C., Shaw, G. M., Le Compte, A., Pretty, C., Desaive, T., & Chase, J. G. (October 2012). Cumulative time in band: glycemic level, variability and patient outcome vs. mortality [Poster presentation]. 37th ANZICS/ACCCN Intensive Care ASM.

Penning, S., Le Compte, A. J., MASSION, P., Moorhead, K. T., Pretty, C., PREISER, J.-C., Shaw, G. M., Suhaimi, F., Desaive, T., & Chase, J. G. (2012). Second pilot trials of the STAR-Liege protocol for tight glycemic control in critically ill patients. BioMedical Engineering OnLine. doi:10.1186/1475-925X-11-58
Peer Reviewed verified by ORBi

Fisk, L. M., Le Compte, A. J., Shaw, G. M., Penning, S., Desaive, T., & Chase, J. G. (2012). Development and Pilot Trial Results of Stochastic Targeted (STAR) Glycemic Control in a Medical ICU. In Proceedings of the 8th IFAC Symposium on Biological and Medical Systems.
Peer reviewed

Penning, S., MASSION, P., Le Compte, A. J., Desaive, T., & Chase, J. G. (August 2012). Insulin Kinetics during Hyper-Insulinemia Euglycemia Therapy (HIET) [Paper presentation]. 8th IFAC Symposium on Biological and Medical Systems, Budapest, Hungary. doi:10.3182/20120829-3-HU-2029.00037

Penning, S., MASSION, P., Le Compte, A. J., Desaive, T., & Chase, J. G. (2012). Insulin Kinetics during Hyper-Insulinemia Euglycemia Therapy (HIET). In Proceedings of the 8th IFAC Symposium on Biological and Medical Systems.
Peer reviewed

Pretty, C., Le Compte, A. J., Chase, J. G., Shaw, G. M., Preiser, J.-C., Penning, S., & Desaive, T. (2012). Variability of insulin sensitivity during the first 4 days of critical illness: implications for tight glycemic control. Annals of Intensive Care. doi:10.1186/2110-5820-2-17
Peer Reviewed verified by ORBi

Penning, S., Le Compte, A. J., Signal, M., MASSION, P., Preiser, J.-C., Shaw, G. M., Desaive, T., & Chase, J. G. (20 March 2012). Does Tight Glycemic Control positively impact on patient mortality? [Poster presentation]. 32nd International Symposium on Intensive Care and Emergency Medicine, Bruxelles, Belgium.

Penning, S., Le Compte, A. J., Signal, M., MASSION, P., PREISER, J.-C., Shaw, G. M., Desaive, T., & Chase, J. G. (2012). Does Tight Glycemic Control positively impact on patient mortality? In Critical Care.
Peer reviewed

Penning, S., & MASSION, P. (16 March 2012). Le contrôle de la glycémie [Paper presentation]. Festival ImagéSanté.

Fisk, L. M., Le Compte, A. J., Shaw, G. M., Penning, S., Desaive, T., & Chase, J. G. (March 2012). Pilot Trial of STAR in Medical ICU [Poster presentation]. 32nd International Symposium on Intensive Care and Emergency Medicine, Bruxelles, Belgium.

Moermans, A., Taccone, F., Penning, S., Desaive, T., Chase, J., & PREISER, J.-C. (2012). Evolution de l’insulino-résistance au cours de l’hypothermie thérapeutique. In Proceedings des journees francophone de nutrition 2012.
Peer reviewed

Evans, A., Le Compte, A., Tan, C.-S., Ward, L., Steel, J., Pretty, C. G., Penning, S., Suhaimi, F., Shaw, G. M., Desaive, T., & Chase, J. G. (2012). Stochastic Targeted (STAR) Glycemic Control - Design, Safety and Performance. Journal of Diabetes Science and Technology. doi:10.1177/193229681200600113
Peer Reviewed verified by ORBi

Ward, L., Steel, J., Le Compte, A., Evans, A., Tan, C.-S., Penning, S., Shaw, G. M., Desaive, T., & Chase, J. G. (2012). Data Entry Errors and Design for Model-Based Tight Glycemic Control in Critical Care. Journal of Diabetes Science and Technology. doi:10.1177/193229681200600116
Peer Reviewed verified by ORBi

Ward, L., Steel, J., Le Compte, A., Evans, A., Tan, C.-S., Penning, S., Shaw, G. M., Desaive, T., & Chase, J. G. (2012). Interface Design and Human Factors Consideration for Model-Based Tight Glycemic Control in Critical Care. Journal of Diabetes Science and Technology. doi:10.1177/193229681200600115
Peer Reviewed verified by ORBi

Penning, S., Signal, M., PREISER, J.-C., Shaw, G., Le Compte, A., Pretty, C., Desaive, T., & Chase, J. (2012). Cumulative time in band (cTIB): glycemic level, variability and patient outcome vs mortality. In Proceedings of ANZICS 2012.
Peer reviewed

Fisk, L. M., Le Compte, A. J., Shaw, G. M., Penning, S., Desaive, T., & Chase, J. G. (2012). STAR Development and Protocol Comparison. IEEE Transactions on Biomedical Engineering. doi:10.1109/TBME.2012.2214384
Peer Reviewed verified by ORBi

Fisk, L., Le Compte, A., Shaw, G., Penning, S., Desaive, T., & Chase, J. (2012). Pilot Trial of STAR in Medical ICU. Critical Care, 16 (Suppl 1), 176.
Peer Reviewed verified by ORBi

Pretty, C., Le Compte, A., Chase, J., Shaw, G., Penning, S., PREISER, J.-C., & Desaive, T. (2012). Variability of insulin sensitivity during the first 4 days of critical illness. Critical Care, 16 (Suppl 1), 167.
Peer Reviewed verified by ORBi

Penning, S., Le Compte, A. J., PREISER, J.-C., Chase, J. G., & Desaive, T. (December 2011). Glycemic Variability, Hypoglycemia and Organ Failure in the Glucontrol Study [Poster presentation]. 10th Belgian Day on Biomedical Engineering, Bruxelles, Belgium.

Penning, S., Desaive, T., MASSION, P., Le Compte, A. J., Moorhead, K. T., Pretty, C. G., Shaw, G. M., & Chase, J. G. (October 2011). Tight Glycemic Control in Critically Ill Patients: the STAR Framework [Poster presentation]. Diabetes Technology Meeting, San Francisco, United States.

Penning, S., PREISER, J.-C., Desaive, T., & Chase, J. G. (October 2011). Does Intensive Insulin Therapy Reduce the Severity of Organ Failures? [Poster presentation]. Diabetes Technology Meeting, San Francisco, United States.

Chase, J. G., Le Compte, A., Penning, S., Moorhead, K. T., MASSION, P., PREISER, J.-C., Pretty, C. G., Shaw, G. M., & Desaive, T. (2011). Enhanced insulin sensitivity variability in the first 3 days of ICU stay: Implications for TGC. Critical Care.
Peer Reviewed verified by ORBi

Chase, G., Le Compte, A., Penning, S., Moorhead, K., MASSION, P., PREISER, J.-C., Pretty, C., Shaw, G., & Desaive, T. (March 2011). Enhanced insulin sensitivity variability in the first 3 days of ICU stay: Implications for TGC [Poster presentation]. 31st International Symposium on Intensive Care and Emergency Medicine, Bruxelles, Belgium.

Suhaimi, F., Le Compte, A., Penning, S., Pretty, C., PREISER, J.-C., Desaive, T., Shaw, & Chase, G. (March 2011). Validation of a Virtual Patient and Virtual Trials Method for Accurate Prediction of TGC Protocol Performance [Poster presentation]. 31st International Symposium on Intensive Care and Emergency Medicine, Bruxelles, Belgium.

Suhaimi, F., Le Compte, A., Penning, S., Pretty, C. G., PREISER, J.-C., Shaw, G. M., Desaive, T., & Chase, J. G. (2011). Validation of a virtual patient and virtual trials method for accurate prediction of TGC protocol performance. Critical Care.
Peer Reviewed verified by ORBi

Chase, J. G., Le Compte, A. J., PREISER, J.-C., Shaw, G. M., Penning, S., & Desaive, T. (2011). Physiological modeling, tight glycemic control, and the ICU clinician: what are models and how can they affect practice? Annals of Intensive Care, 1:11. doi:10.1186/2110-5820-1-11
Peer Reviewed verified by ORBi

Shaw, G., Le Compte, A., Evans, A., Tan, C., Steel, J., Ward, L., Pretty, C., Penning, S., Desaive, T., & Chase, J. (2011). Safety and Performance of Stochastic Targeted (STAR) TGC of Insulin and Nutrition. In Proceedings of SQAO 2011.
Peer reviewed

Penning, S., Le Compte, A. J., Moorhead, K. T., Desaive, T., MASSION, P., PREISER, J.-C., Shaw, G. M., & Chase, J. G. (2011). First pilot trial of the STAR-Liege protocol for tight glycemic control in critically ill patients. Computer Methods and Programs in Biomedicine. doi:10.1016/j.cmpb.2011.07.003
Peer Reviewed verified by ORBi

Shaw, G. M., Le Compte, A., Evans, A., Tan, C.-S., Steel, J., Ward, L., Pretty, C. G., Penning, S., Desaive, T., & Chase, J. G. (2011). Safety and Performance of Stochastic Targeted (STAR) Glycemic Control of Insulin and Nutrition - First Pilot Results [Poster presentation]. ESICM 2011, Berlin, Germany.

Shaw, G. M., Le Compte, A., Evans, A., Tan, C.-S., Steel, J., Ward, L., Pretty, C. G., Penning, S., Desaive, T., & Chase, J. G. (2011). Safety and Performance of Stochastic Targeted (STAR) Glycemic Control of Insulin and Nutrition – First Pilot Results. Intensive Care Medicine.
Peer Reviewed verified by ORBi

Chase, J. G., Le Compte, A. J., PREISER, J.-C., Pretty, C. G., Moorhead, K., Penning, S., Shaw, G. M., & Desaive, T. (2011). Insulin Sensitivity, Its Variability and Glycemic Outcome: A model-based analysis of the difficulty in achieving tight glycemic control in critical care. In 18th World Congress of the International Federation of Automatic Control (IFAC).
Peer reviewed

Pretty, C. G., Le Compte, A., PREISER, J.-C., MASSION, P., Penning, S., Moorhead, K. T., Shaw, G. M., Desaive, T., & Chase, J. G. (2011). Variability of insulin sensitivity for diabetics and non-diabetics during the first 3 days of ICU stay [Poster presentation]. ESICM 2011, Berlin, Germany.

Pretty, C. G., Le Compte, A., PREISER, J.-C., MASSION, P., Penning, S., Moorhead, K. T., Shaw, G. M., Desaive, T., & Chase, J. G. (2011). Variability of insulin sensitivity for diabetics and non-diabetics during the first 3 days of ICU stay. Intensive Care Medicine, 37 (Suppl 1), 100.
Peer Reviewed verified by ORBi

Chase, J. G., Le Compte, A. J., Evans, A., Ward, L., Steel, J., Tan, C. S., Pretty, C. G., Penning, S., Desaive, T., & Shaw, G. M. (2011). Tight Glycemic Control in Intensive Care: From engineering to clinical practice change. In 5th European Conference of the International Federation for Medical and Biological Engineering.
Peer reviewed

Penning, S., Le Compte, A. J., PREISER, J.-C., Chase, J. G., & Desaive, T. (2011). Glycemic Variability, Hypoglycemia and Organ Failure in the Glucontrol Study. In 10th Belgian Day on Biomedical Engineering.
Peer reviewed

Evans, A., Shaw, G. M., Le Compte, A., Tan, C.-S., Ward, L., Steel, J., Pretty, C. G., Pfeifer, L., Penning, S., Suhaimi, F., Signal, M., Desaive, T., & Chase, J. G. (2011). Pilot proof of concept clinical trials of Stochastic Targeted (STAR) glycemic control. Annals of Intensive Care, 1, 38. doi:10.1186/2110-5820-1-38
Peer Reviewed verified by ORBi

Penning, S., Le Compte, A., MASSION, P., Moorhead, K. T., PREISER, J.-C., Shaw, G. M., Desaive, T., & Chase, J. G. (2011). Pilot Trials of STAR Target to Range Glycemic Control. Intensive Care Medicine, 37 (Suppl 1), 100.
Peer Reviewed verified by ORBi

Penning, S., Le Compte, A., MASSION, P., Moorhead, K. T., PREISER, J.-C., Shaw, G. M., Desaive, T., & Chase, J. G. (2011). Pilot Trials of STAR Target to Range Glycemic Control [Poster presentation]. ESICM 2011, Berlin, Germany.

Penning, S., Le Compte, A., Desaive, T., Moorhead, K., & Chase, J. G. (26 November 2010). Tight Glycemic Control Models for Critically Ill Patients in Intensive Care Units [Poster presentation]. 9th Belgian Day on Biomedical Engineering, Bruxelles, Belgium.

Penning, S., Le Compte, A., Moorhead, K., Desaive, T., & Chase, J. G. (2010). Tight Glycemic Control Models for Critically Ill Patients in Intensive Care Units. In 9th Belgian Day on Biomedical Engineering, "Bridging the gap between medicine and engineering', Friday November 26th 2010 in the Academy Palace, Hertogstraat 1, 1000 Brussels.

LeCompte, A. J., Penning, S., Moorhead, K., Massion, P., Preiser, J.-C., Shaw, G. M., Desaive, T., & Chase, J. G. (2010). Pilot Trials of the STAR TGC Protocol in a Cardiac Surgery ICU. In Proceedings of the 10th Annual Diabetes Technology Meeting.
Peer reviewed

Chase, J. G., Suhaimi, F., Penning, S., PREISER, J.-C., Le Compte, A. J., Lin, J., Pretty, C. G., Shaw, G. M., Moorhead, K., & Desaive, T. (2010). Validation of a model-based virtual trials method for tight glycemic control in intensive care. BioMedical Engineering OnLine, 9, 84. doi:10.1186/1475-925X-9-84
Peer Reviewed verified by ORBi

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