Profil

Herkenne Stéphanie

GIGA Cancer - Molecular Angiogenesis Laboratory

Département des sciences de la vie

See author's contact details
ORCID
0000-0002-2106-9360
Main Referenced Co-authors
Struman, Ingrid  (16)
Martial, Joseph  (11)
Bajou, Khalid  (8)
Scorrano, Luca (7)
Nguyen, Ngoc-Quynh-Nhu  (6)
Main Referenced Keywords
angiogenesis (3); microRNA (2); 16K hPRL (1); Angiogenèse (1); Animals (1);
Main Referenced Unit & Research Centers
GIGA-LAM - GIGA Cancer-Molecular Angiogenesis Laboratory - ULiège [BE] (1)
UNIPD - University of Padua (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (46)
Human health sciences: Multidisciplinary, general & others (1)
Anatomy (cytology, histology, embryology...) & physiology (1)

Publications (total 48)

The most downloaded
452 downloads
Herkenne, S. (2013). Détermination du rôle de l'interactome PAI-1/uPA/uPAR dans l'angiogenèse [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/153730 https://hdl.handle.net/2268/153730

The most cited

378 citations (Scopus®)

naon, D., zaninello, M., giacomello, M., varanita, T., grespi, F., Lakshminaranayan, S., Serafini, A., semenzato, M., Herkenne, S., hernadez-alvarez, M., zorzano, A., De stefani, D., Dworn, G., & Scorrano, L. (2016). Critical reappraisal confirms that Mitofusin 2 is anendoplasmic reticulum–mitochondria tether. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1606786113 https://hdl.handle.net/2268/253814

Herkenne, S. (24 June 2024). Targeting mitochondria to inhibit angiogenesis and treat cancer [Paper presentation]. ephar 2024.
Peer reviewed

Herkenne, S. (20 June 2024). Mitochondria a new player in endosomal trafficking and cell-to-cell communication [Paper presentation]. 6th symposium mitochondria in Netherland, Maastricht, Netherlands.
Peer reviewed

Verrillo, G., Obeid, A. M., Genco, A., Scrofani, J., Orange, F., Hanache, S., Mignon, J., Leyder, T., Michaux, C., Kempeneers, C., Bricmont, N., Herkenne, S., Vernos, I., Martin, M., & Mottet, D. (2024). Non-canonical role for the BAF complex subunit DPF3 in mitosis and ciliogenesis. Journal of Cell Science. doi:10.1242/jcs.261744
Peer Reviewed verified by ORBi

Herkenne, S. (01 December 2023). 1. Mitochondria control the communication of cancer cells with the tumor microenvironment [Paper presentation]. Mitochondrie apoptosis and cancer meeting, coimbra, Portugal.
Peer reviewed

Herkenne, S. (02 October 2023). 2. MDVs control endosomal maturation [Paper presentation]. EMBO contacts sites meeting.
Peer reviewed

Marchesan, E., Alice Nardin, Sofia Mauri, Simone Di Paola, Monica Chinellato, Sophia von Stockum, Joy Chakraborty, Herkenne, S., Valentina Basso, Emilie Schrepfer, Oriano Marin, Laura Cendron, Diego L. Medina, Luca Scorrano, & Elena Ziviani. (2023). Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/304655.

Herkenne, S. (06 September 2022). Mitochondria: new regulator of endosomal trafficking [Paper presentation]. GIGA day.
Peer reviewed

Herkenne, S. (24 June 2022). Mitochondria: new regulator of endosomal pathway [Paper presentation]. talk IBM.
Peer reviewed

NJOCK, M.-S.* , O'Grady, T.* , Nivelles, O., Lion, M., Jacques, S., Cambier, M., Herkenne, S., Muller, F., Christian, A., REMACLE, C., GUIOT, J., Rahmouni, S., Dequiedt, F.* , & Struman, I.*. (June 2022). Endothelial extracellular vesicles promote tumour growth by tumour-associated macrophage reprogramming. Journal of Extracellular Vesicles, 11 (6), 12228. doi:10.1002/jev2.12228
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Herkenne, S. (08 April 2022). Regulation of endosomal trafficking by mitochondrial dynamic and mitochondria-derived vesicles [Paper presentation]. Séminaire TELEVIE.
Peer reviewed

Herkenne, S. (17 March 2022). Mitochondrial dynamic regulates miRNA expression in breast cancer [Paper presentation]. Meeting NARILIS.
Peer reviewed

Zamberlan, M.* , Boeckx, A.* , Muller, F., Vinelli, F., Ek, O., Vianello, C., Coart, E., Shibata, K., Christian, A., Grespi, F., Giacomello, M., Struman, I., Scorrano, L.* , & Herkenne, S.*. (12 March 2022). Inhibition of the mitochondrial protein Opa1 curtails breast cancer growth. Journal of Experimental and Clinical Cancer Research, 41 (1), 95. doi:10.1186/s13046-022-02304-6
Peer reviewed
* These authors have contributed equally to this work.

Fontaine, M., Herkenne, S., Ek, O., Paquot, A., Boeckx, A., Paques, C., Nivelles, O., Thiry, M., & Struman, I. (2022). Extracellular Vesicles Mediate Communication between Endothelial and Vascular Smooth Muscle Cells. International Journal of Molecular Sciences, 23 (1). doi:10.3390/ijms23010331
Peer Reviewed verified by ORBi

Bean, C., Audano, A., Varanita, T., Favaretto, F., Medaglia, M., Gerdol, M., Pernas, L., Giacomello, M., Herkenne, S., Muniandy, M., Heinonen, S., Milan, G., Pallavicini, A., Pietiläinen, K., Vettor, R., Mitro, N., & Scorrano, L. (2021). The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites. Nature Metabolism. doi:10.1038/s42255-021-00497-2
Peer reviewed

Herkenne, S. (17 November 2021). the mitochondrial fission factor dynamin related protein 1 (DRP1) limits angiogenesis by interfering with VEGFR2 trafficking [Paper presentation]. Société française d'angiogenèse.
Peer reviewed

Herkenne, S., & Scorrano, L. (13 November 2020). OPA1, a new mitochondrial target in cancer therapy. Aging, 12, 20931-20933. doi:10.18632/aging.104207
Peer Reviewed verified by ORBi

Herkenne, S., ek, O., Zamberlan, M., Pellatiero, A., Chergova, M., chivite, L., Novotna, E., Rigoni, G., Fonseca, T., samardzic, D., Agnellini, A., Bean, C., Di Benedetto, G., Tiso, N., Argenton, F., viola, A., Sorianno, M., Giacommello, M., Ziviani, E., ... Scorrano, L. (2020). Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1. Cell Metabolism. doi:10.1016/j.cmet.2020.04.007
Peer Reviewed verified by ORBi

Angioni, R., Liboni, C., Herkenne, S., Sanchez-Rodriguez, R., Borile, G., Marcuzzi, E., Cali, B., Muraca, M., & Viola, A. (2020). CD73 + extracellular vesicles inhibit angiogenesis through adenosine A 2B receptor signalling. Journal of Extracellular Vesicles. doi:10.1080/20013078.2020.1757900
Peer Reviewed verified by ORBi

Herkenne, S. (2020). mitochondria and vesicles link [Paper presentation]. Présentation young investigator.

Herkenne, S. (2020). Mitochondria and EVs [Paper presentation]. Young PI selection CECAD, Cologne, Germany.
Peer reviewed

Zaninello, M., Palikaras, K., Naon, D., Iwata, K., Herkenne, S., Quintana-Cabrera, R., Semenzato, M., Grespi, F., Ross-Cisneros, F., Carelli, V., Sadun, A., Tavernarakis, N., & Scorrano, L. (2020). Inhibition of autophagy curtails visual loss in a model of autosomal dominant optic atrophy. Nature Communications. doi:10.1038/s41467-020-17821-1
Peer Reviewed verified by ORBi

Herkenne, S. (2019). Developmental and tumor angiogenesis requires changes in endothelial cell mitochondria-shaping protein OPA1 [Paper presentation]. 6th Biannual Meeting on Mitochondria Apoptosis & Cancer, Prague, CSK.
Peer reviewed

Herkenne, S., & Herkenne, S. (2019). The mitochondrial fission factor Dynamin-related protein 1 (Drp1) limits VEGF/VEGFR2 endocytic trafficking and angiogenesis [Paper presentation]. meeting in Padova.
Peer reviewed

Herkenne, S. (2019). Developmental and tumor angiogenesis requires changes in endothelial cell mitochondrial shape [Paper presentation]. 3rd retreat of the Department of Biology, University of Padova, Padova, Italy.
Peer reviewed

Herkenne, S. (2019). 3. The mitochondrial fission factor Dynamin Related Protein 1 limits VEGF/VEGFR2 endocytic trafficking and angiogenesis [Paper presentation]. 3rd ESM-EVBO Conference, Maastricht, Netherlands.
Peer reviewed

Herkenne, S. (15 October 2018). The mitochondria shaping protein Optic Atrophy 1 (OPA1) controls angiogenesis [Paper presentation]. Société française d'angiogenèse.
Peer reviewed

Naon, D., Zaninello, M., Giacommello, M., Varanita, T., Grespi, F., Lakshminaranayan, S., Serafini, A., Semenzato, M., Herkenne, S., Hernández-Alvarez, Zorzano, A., De Stefani, D., Dworn, G., & Scorrano, L. (2017). Reply to Filadi et al.: Does Mitofusin 2 tether or separate endoplasmic reticulum and mitochondria? Proceedings of the National Academy of Sciences of the United States of America.
Peer Reviewed verified by ORBi

Loubiere, C., Clavel, S., Gilleron, J., Harisseh, R., Fauconnier, J., Ben-Sahra, I., Kaminski, L., Laurent, K., Herkenne, S., Lacas-Gervais, S., Ambrosetti, D., Alcor, D., Rocchi, S., Cormont, M., Michiels, J., Mari, B., mazure, N., scorrano, L., lacampagne, A., ... Bost, F. (2017). The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells. Scientific Reports. doi:10.1038/s41598-017-05052-2
Peer Reviewed verified by ORBi

Herkenne, S. (2016). The mitochondrial shaping protein Optic Atrophy 1 (OPA1) controls angiogenesis and tumor growth [Paper presentation]. pADOVA-iNBRUCK MEETING.
Peer reviewed

Herkenne, S. (2016). The mitochondrial shaping protein Optic Atrophy 1 (OPA1) controls angiogenesis, lymphangiogenesis and tumor growth [Paper presentation]. Mito Insbruck-Padova, Insbruck, Austria.
Peer reviewed

naon, D., zaninello, M., giacomello, M., varanita, T., grespi, F., Lakshminaranayan, S., Serafini, A., semenzato, M., Herkenne, S., hernadez-alvarez, M., zorzano, A., De stefani, D., Dworn, G., & Scorrano, L. (2016). Critical reappraisal confirms that Mitofusin 2 is anendoplasmic reticulum–mitochondria tether. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1606786113
Peer Reviewed verified by ORBi

Herkenne, S., Paques, C., Nivelles, O., Lion, M., BAJOU, K., Pollenus, T., Fontaine, M., Carmeliet, P., Martial, J., Nguyen, N.-Q.-N., & Struman, I. (2015). The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis. Science Signaling, 8 (403), 117. doi:10.1126/scisignal.aaa2403
Peer Reviewed verified by ORBi

Herkenne, S. (2015). The mitochondria shaping protein Optic Atrophy 1 (OPA1) controls angiogenesis [Paper presentation]. Société française d'angiogenèse, Paris, France.

Herkenne, S. (2015). The mitochondria shaping protein Optic Atrophy 1 (OPA1) controls angiogenesis [Paper presentation]. 6ème congrès de la SFA à Paris.
Peer reviewed

Herkenne, S. (21 October 2014). Involvement of mitochondrial dynmics in the regulation of angiogenesis [Paper presentation]. EMBO interview.
Peer reviewed

Paques, C., Herkenne, S., Pollenus, T., & Struman, I. (May 2014). Growth Factors-Induced Angiogenesis Requires uPAR on Endothelial Cells [Poster presentation]. Giga Cancer Day, Liège, Belgium.

Bajou, K.* , Herkenne, S.* , Thijssen, V. L., D'Amico, S., Nguyen, N.-Q.-N., Bouche, A., Tabruyn, S., Srahna, M., Carabin, J.-Y., Nivelles, O., Paques, C., Cornelissen, Y., Lion, M., Noël, A., Gils, A., Vinckier, S., Declerck, P. J., Griffioen, A. W., Dewerchin, M., ... Struman, I. (2014). PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin. Nature Medicine, (7), 741. doi:10.1038/nm.3552
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Herkenne, S. (2013). Détermination du rôle de l'interactome PAI-1/uPA/uPAR dans l'angiogenèse [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/153730

Paques, C., Herkenne, S., & Struman, I. (2013). Tumor-Induced Angiogenesis Requires uPAR on Endothelial Cells [Poster presentation]. Giga Cancer Day.

Herkenne, S., Bajou, K., Nguyen, N.-Q.-N., Martial, J., & Struman, I. (19 May 2012). Implication of the PAI-1/uPA/uPAR signalosome in the antiangiogenic action of 16K prolactin [Poster presentation]. GIGA-Cancer Day, Liège, Belgium.

Herkenne, S., Dalla Valle, A., Bajou, K., Nguyen, N.-Q.-N., Martial, J., & Struman, I. (April 2012). Implication of the PAI-1/uPA/uPAR complex in the antiangiogenic action of 16K prolactin [Poster presentation]. Biomedica, Liège, Belgium.

Herkenne, S., Dalla Valle, A., Bajou, K., Nguyen, N.-Q.-N., Martial, J., & Struman, I. (2012). Implication of the PAI-1/uPA/uPAR complex in the antiangiogenic action of 16K hPRL [Poster presentation]. Keystone symposia on Angiogenesis: Advances in Basic Science and Therapeutic Applications, Snowbird, United States - Utah.

Nguyen, N.-Q.-N., Castermans, K., Berndt, S., Herkenne, S., Tabruyn, S., Blacher, S., Lion, M., Noël, A., Martial, J., & Struman, I. (07 November 2011). The Antiangiogenic 16K Prolactin Impairs Functional Tumor Neovascularization by Inhibiting Vessel Maturation. PLoS ONE, 6 (11), 27318-27318. doi:10.1371/journal.pone.0027318
Peer Reviewed verified by ORBi

Nguyen, N.-Q.-N., Castermans, K., Berndt, S., Herkenne, S., Tabruyn, S., Blacher, S., Lion, M., Noël, A., Martial, J., & Struman, I. (May 2011). The antiangiogenic 16K prolactin disturbs functional tumor neovascularization by affecting vessel maturation [Poster presentation]. 4th International Meeting on Angiogenesis, Amsterdam, Netherlands.

Herkenne, S., Bajou, K., D'Amico, S., Nguyen, N.-Q.-N., Martial, J., & Struman, I. (2011). Implication of the PAI-1/uPA/uPAR complex in the effects of the antiangiogenic factor 16K hPRL [Poster presentation]. Giga cancer day, Liège, Belgium.

Bajou, K., Herkenne, S., Thijssen, V. L., D'Amico, S., Srahna, M., Carabin, J.-Y., Gils, A., Declerck, P. J., Griffioen, A. W., Martial, J., & Struman, I. (January 2011). PAI-1 mediates antiangiogenic and fibrinolytic actions of prolactin/growth hormone 16-14K fragments [Poster presentation]. Giga-Day Symposia, Liège, Belgium.

Kinet, V., Castermans, K., Herkenne, S., Maillard, C., Blacher, S., Lion, M., Noël, A., Martial, J., & Struman, I. (2011). The Angiostatic Protein 16K Human Prolactin Significantly Prevents Tumor-Induced Lymphangiogenesis by Affecting Lymphatic Endothelial Cells. Endocrinology. doi:10.1210/en.2011-1081
Peer Reviewed verified by ORBi

Herkenne, S., Bajou, K., D'Amico, S., Martial, J., & Struman, I. (21 May 2010). Study of the signalling pathway of 16K PRL and 14K GH for mediate their anti-angiogenic effect [Poster presentation]. GIGA-Cancer Day, Liège, Belgium.

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