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Fleron Maximilien

GIGA Platforms

Département de chimie (sciences) > Chimie analytique inorganique

See author's contact details
Main Referenced Co-authors
Mazzucchelli, Gabriel  (30)
Baiwir, Dominique  (26)
Eppe, Gauthier  (22)
De Pauw, Edwin  (20)
Louis, Edouard  (15)
Main Referenced Keywords
Gold nanorods (7); Optoacoustic (4); optoacoustic (4); Prostate cancer (4); prostate cancer (4);
Main Referenced Unit & Research Centers
Giga-Systems Biology and Chemical Biology - ULiège (8)
MolSys - Molecular Systems - ULiège (8)
CART - Centre Interfacultaire d'Analyse des Résidus en Traces - ULiège (3)
Giga-Cancer - ULiège (2)
Laboratoire de Spectrométrie de Masse (1)
Main Referenced Disciplines
Gastroenterology & hepatology (15)
Chemistry (14)
Biochemistry, biophysics & molecular biology (11)
Oncology (3)
Biotechnology (3)

Publications (total 40)

The most downloaded
294 downloads
Mazzucchelli, G., Gabelica, V., Smargiasso, N., Fleron, M., Ashimwe, W., Rosu, F., De Pauw-Gillet, M.-C., Riou, J.-F., & De Pauw, E. (2008). Proteome alteration induced by hTERT transfection of human fibroblast cells. Proteome Science, 6 (1), 12. doi:10.1186/1477-5956-6-1 https://hdl.handle.net/2268/601

The most cited

83 citations (OpenAlex)

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8 https://hdl.handle.net/2268/288940

Berkal, M. A., Kune, C., Fleron, M., Baiwir, D., Sophie Gohy, Eppe, G., & Mazzucchelli, G. (06 December 2025). Optimisation of Sample Preparation for Analysing Cystic Fibrosis Biomarkers in Sweat using LC-TIMS-TOF [Poster presentation]. Belgian Proteomics Association Conference (BePAc 2024), Ghent, Belgium.

Meuwis, M.-A., Baiwir, D., Fleron, M., Mazzucchelli, G., BOUTAFFALA, L., Reenaers, C., Van Kemseke, C., Vieujean, S., Bettonville, V., BRIQUET, A., Lechanteur, C., COIMBRA MARQUES, C., & Louis, E. (21 February 2025). Perianal Fistula Closure after Heterologous Mesenchymal Stem Cell Injections is Associated with Protein Levels indicating Lower Tissue Immune Infiltrate, Specific Proteins Involved in the Control of Apoptosis, and Probable Higher Tissues Remodeling and Proteasome Activity [Poster presentation]. 20th Congress of European Crohn's and Colitis Organisation, Berlin, Germany.
Peer reviewed

Meuwis, M.-A., Loly, J.-P., Salée, C., Massot, C., Baiwir, D., Fleron, M., Mazzucchelli, G., Vieujean, S., Somja, J., & Louis, E. (21 February 2025). Proteomic Profiles Associated with Residual Ultrastructural Anomalies in the Epithelium of IBD patients in Endoscopic Remission [Poster presentation]. 20th Congress of European Crohn's and Colitis Organisation, Berlin, Germany.
Peer reviewed

Meuwis, M.-A., Baiwir, D., Fleron, M., Mazzucchelli, G., BOUTAFFALA, L., Reenaers, C., Van Kemseke, C., Vieujean, S., Bettonville, V., BRIQUET, A., LECHANTEUR, C., COIMBRA MARQUES, C., & Louis, E. (12 February 2025). Perianal fistula closure after heterologous mesenchymal stem cell injections is associated with protein levels indicating lower tissue immune infiltrate, specific proteins involved in the control of apoptosis, and probable higher tissues remodeling and proteasome activity [Poster presentation]. 37th edition of Belgian Week of Gastroenterology.
Peer reviewed

Meuwis, M.-A., Loly, J.-P., Salée, C., Massot, C., Baiwir, D., Fleron, M., Mazzucchelli, G., Vieujean, S., Somja, J., & Louis, E. (12 February 2025). Proteomic profiles associated with residual ultrastructural anomalies in the epithelium of IBD patients in endoscopic remission [Poster presentation]. 37th edition of Belgian Week of Gastroenterology, Liège, Belgium.
Peer reviewed

Hodeige, M., Kune, C., Bertrand, V., Fleron, M., Baiwir, D., Sounni, N. E., Eppe, G., Gatto, L., & Mazzucchelli, G. (24 January 2025). Linking spatial to functional proteomics on heterogeneous samples: The “pixel-by-pixel” shotgun proteomic approach [Poster presentation]. Molsys day, Liège, Belgium.

Burat, B., Berkal, M. A., Kune, C., Fleron, M., Baiwir, D., Sophie Gohy, Eppe, G., & Mazzucchelli, G. (06 December 2024). Comprehensive Sweat Proteome Characterization and Identification of Cystic Fibrosis Biomarkers: Optimizing Sample Preparation for a new MS-Based Proteomic Approach [Paper presentation]. Belgian Proteomics Association Conference (BePAc 2024), Ghent, Belgium.

Hodeige, M., Kune, C., Fleron, M., Baiwir, D., Sounni, N. E., Eppe, G., Gatto, L., & Mazzucchelli, G. (05 December 2024). Linking spatial to functional proteomics on heterogeneous samples: The “pixel-by-pixel” shotgun proteomic approach [Paper presentation]. Belgian Proteomics Association Conference, Gent, Belgium.

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., De Pauw, E., Laharie, D., Satsangi, J., Bossuyt, P., Vuitton, L., Vieujean, S., Colombel, J.-F., Meuwis, M.-A., Louis, E., & GETAID and the SPARE-Biocycle research group. (2024). External validation of serum biomarkers predicting short-term and mid/long-term relapse in patients with Crohn's disease stopping infliximab. Gut, 2024-332648. doi:10.1136/gutjnl-2024-332648
Peer Reviewed verified by ORBi

Pierre, N., Huynh-Thu, V. A., Baiwir, D., VIEUJEAN, S., Bequet, E., Reenaers, C., Van Kemseke, C., Salée, C., Massot, C., Fleron, M., Mazzucchelli, G., Trzpiot, L., Eppe, G., De Pauw, E., Louis, E., & Meuwis, M.-A. (2024). Serum proteome signatures associated with ileal and colonic ulcers in Crohn's disease. Journal of Proteomics, 105199. doi:10.1016/j.jprot.2024.105199
Peer Reviewed verified by ORBi

Pierre, N., Huynh-Thu, V. A., Baiwir, D., VIEUJEAN, S., Bequet, E., Reenaers, C., Van Kemseke, C., Salée, C., Massot, C., Fleron, M., Mazzucchelli, G., Trzpiot, L., Eppe, G., De Pauw, E., Louis, E., & Meuwis, M.-A. (02 February 2024). Distinct blood protein profiles associated with ileal and colonic ulcers in Crohn’s disease [Poster presentation]. Belgian Week of Gastroenterology 2024, Antwerp, Belgium.
Peer reviewed

Pierre, N., Huynh-Thu, V. A., Baiwir, D., VIEUJEAN, S., Bequet, E., Reenaers, C., Van Kemseke, C., Salée, C., Massot, C., Fleron, M., Mazzucchelli, G., Trzpiot, L., Eppe, G., De Pauw, E., Louis, E., & Meuwis, M.-A. (2024). Distinct blood protein profiles associated with ileal and colonic ulcers in Crohn’s disease [Poster presentation]. European Crohn's and Colitis Organisation 2024, Stockholm, Sweden.
Peer reviewed

Pierre, N., Huynh-Thu, V. A., Baiwir, D., VIEUJEAN, S., Bequet, E., Reenaers, C., Van Kemseke, C., Salée, C., Massot, C., Fleron, M., Mazzucchelli, G., Trzpiot, L., Eppe, G., De Pauw, E., Louis, E., & Meuwis, M.-A. (2024). Distinct blood protein profiles associated with ileal and colonic ulcers in Crohn’s disease [Paper presentation]. Belgian Week of Gastroenterology 2024.
Peer reviewed

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., Laharie, D., Satsangi, J., Colombel, J. F., Hertervig, E., Meuwis, M.-A., & Louis, E. (30 January 2023). Distinct biological profiles associated with the risk of short-term relapse and mid/long-term relapse in Crohn’s disease patients stopping infliximab. Journal of Crohn's and Colitis, 17 (Supplement_1), 3-i6. doi:10.1093/ecco-jcc/jjac190.0002
Peer Reviewed verified by ORBi

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., David Laharie, Jack Satsangi, Jean-Frédéric Colombel, Erik Hertervig, Meuwis, M.-A., & Louis, E. (2023). Distinct biological profiles associated with the risk of short-term relapse and mid/long-term relapse in Crohn’s disease patients stopping infliximab. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., David Laharie, Jack Satsangi, Jean-Frédéric Colombel, Erik Hertervig, Meuwis, M.-A., & Louis, E. (2023). Distinct biological profiles associated with the risk of short-term relapse and mid/long-term relapse in Crohn’s disease patients stopping infliximab [Paper presentation]. European Crohn's and Colitis Organisation (ECCO) congress.
Peer reviewed

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., David, L., Jack, S., Jean-Frédéric, C., Erik, H., Meuwis, M.-A., & Louis, E. (2023). Distinct biological profiles associated with the risk of short-term relapse and mid/long-term relapse in Crohn’s disease patients stopping infliximab [Paper presentation]. Belgian Week of Gastroenterology 2023.
Peer reviewed

Burat, B., Reynaerts, A., Baiwir, D., Fleron, M., Gohy, S., Eppe, G., Leal, T.* , & Mazzucchelli, G.*. (31 July 2022). Sweat Proteomics in Cystic Fibrosis: Discovering Companion Biomarkers for Precision Medicine and Therapeutic Development. Cells, 11 (15), 2358. doi:10.3390/cells11152358
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Kune, C., Fleron, M., Baiwir, D., Vandormael, D., Gilet, T., Nguyen, L., Eppe, G., & Mazzucchelli, G. (15 June 2022). Minimizing the peptide loss due to interactions with custom consumable materials for proteomic study of protein samples at very low concentrations [Poster presentation]. 5th Single Cell Proteomics Conference (SCP) 2022, Boston, United States - Massachusetts.
Peer reviewed

Kune, C., Tielens, S., Fleron, M., Baiwir, D., Nguyen, L., Eppe, G., & Mazzucchelli, G. (07 June 2022). From Downscaling to Single-Cell Proteomic: Understanding and minimizing the downscaling effect [Poster presentation]. 70th American Society for Mass Spectrometry (ASMS) annual conference, Minneapolis, United States - Minnesota.
Peer reviewed

Kune, C., Fleron, M., Baiwir, D., Vandormael, D., Gilet, T., Nguyen, L., Eppe, G., & Mazzucchelli, G. (30 May 2022). Minimizing the peptide/protein loss due to interactions with custom consumable materials for proteomic study of protein samples at very low concentrations [Poster presentation]. Next-Generation Protein Analysis and Detection (NGPAD), 4th edition, Ghent, Belgium.
Peer reviewed

Kune, C., Fleron, M., Baiwir, D., Vandormael, D., Gilet, T., Nguyen, L., Eppe, G., & Mazzucchelli, G. (04 May 2022). Minimize peptide/protein loss due to interactions with custom consumable materials for very low concentration protein samples [Paper presentation]. Belgian Proteomics Association Congress 2022 (BEPaC 2022), Liège, Belgium.

Pierre, N., Baiwir, D., Mazzucchelli, G., Fleron, M., PAULISSEN, G., Huynh-Thu, V. A., De Pauw, E., Eppe, G., LOUIS, E., & MEUWIS, M.-A. (04 May 2022). Improving precision of selected reaction monitoring with a two steps internal standard normalisation [Paper presentation]. 5th Symposium of the Belgian Proteomics Association.
Peer reviewed

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pierre, N., Baiwir, D., Mazzucchelli, G., Fleron, M., Paulissen, G., Huynh-Thu, V. A., De Pauw, E., Eppe, G., Louis, E., & Meuwis, M.-A. (2022). Improving precision of selected reaction monitoring with a two steps internal standard normalisation [Poster presentation]. Next-Generation Protein Analysis and Detection (4th edition), Ghent, Belgium.
Editorial reviewed

Burat, B.* , Reynaerts, A.* , Baiwir, D., Fleron, M., Eppe, G., Leal, T.* , & Mazzucchelli, G.*. (08 October 2021). Characterization of the Human Eccrine Sweat Proteome—A Focus on the Biological Variability of Individual Sweat Protein Profiles. International Journal of Molecular Sciences, 22 (19). doi:10.3390/ijms221910871
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Alevra Sarika, N.* , Payen, V.* , Fleron, M., Ravau, J., Brusa, D., Najimi, M., De Pauw, E., Eppe, G., Mazzucchelli, G., Sokal, E., des Rieux, A., & El Taghdouini, A. (30 May 2020). Human Liver-Derived Extracellular Matrix for the Culture of Distinct Human Primary Liver Cells. Cells, 9(6). doi:10.3390/cells9061357
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Fléron, M. (2013). Specific protein identification and targeting of prostate cancer cells [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315390

Schol, D., Fléron, M., Greisch, J. F., Jaeger, M., Frenz, M., De Pauw, E., & De Pauw-Gillet, M.-C. (2013). Anti-PSMA antibody-coupled gold nanorods detection by optical and electron microscopies. Micron, (50), 68-74. doi:10.1016/j.micron.2013.05.003
Peer Reviewed verified by ORBi

Schol, D., Fléron, M., De Pauw-Gillet, M.-C., & De Pauw, E. (11 September 2012). Functionalized Gold Nanorods for Optoacoustic Cancer Detection: From Chemical Synthesis to Biological Assessment [Paper presentation]. International Conference on Chemistry for Health 2012, Athens, Greece.

Fleron, M., Greffe, Y., Musmeci, D., Massart, A.-C., Hennequière, V., Mazzucchelli, G., Waltregny, D., De Pauw-Gillet, M.-C., De Pauw, E., Castronovo, V., & Turtoi, A. (10 September 2010). Novel post-digest isotope coded protein labeling method for phospho- and glycoproteome analysis. Journal of Proteomics, 73 (10), 1986-2005. doi:10.1016/j.jprot.2010.06.003
Peer Reviewed verified by ORBi

Fleron, M., Greffe, Y., Massart, A.-C., Hennequière, V., Musmeci, D., Mazzucchelli, G., De Pauw-Gillet, M.-C., Castronovo, V., De Pauw, E., & Turtoi, A. (16 April 2010). Novel Relative ICPL Based Quantitative Phospho- and Glycoproteome Analysis Method [Poster presentation]. Belgian Society for Mass Spectrometry : Annual Meeting 2010, Leuven, Belgium.

Schol, D., Fleron, M., Greisch, J.-F., De Pauw-Gillet, M.-C., De Pauw, E., Jaeger, M., Frenz, M., Eccles, S., Bamber, J., Frosini, S., Massotti, L., Fournelle, M., & Lemor, R. (12 September 2008). Functionalized plasmonic gold nanoparticles for optoacoustic cancer detection [Poster presentation]. World Molecular Imaging Congress (WMIC), Nice, France.

Schol, D., Fleron, M., Greisch, J.-F., De Pauw-Gillet, M.-C., De Pauw, E., Jaeger, M. (Other coll.), & Frenz, M. (Other coll.). (12 March 2008). Optoacoustic specific detection of prostate cancer using functionalized gold nanorods [Poster presentation]. Medical Imaging 2008.

Schol, D., Fleron, M., Greisch, J.-F., De Pauw-Gillet, M.-C., De Pauw, E., Jaeger, M., Frenz, M., Eccles, S., Bamber, J., Frozini, S., Masotti, L., Fournelle, M., & Lemor, R. (2008). LNCaP prostate cancer imaging with biologically functionalized gold nanoparticles in 2D and 3D cell culture. Anticancer Research, 28, 3258.

Mazzucchelli, G., Gabelica, V., Smargiasso, N., Fleron, M., Ashimwe, W., Rosu, F., De Pauw-Gillet, M.-C., Riou, J.-F., & De Pauw, E. (2008). Proteome alteration induced by hTERT transfection of human fibroblast cells. Proteome Science, 6 (1), 12. doi:10.1186/1477-5956-6-1
Peer Reviewed verified by ORBi

Fleron, M., Schol, D., Greisch, J.-F., De Pauw, E., & De Pauw-Gillet, M.-C. (16 November 2007). Optoacoustic specific detection of prostate cancer using functionalized gold nanorods [Poster presentation]. Réunion de la Société Belge de Microscopie, Liège, Belgium.

Fleron, M., Schol, D., Greisch, J.-F., De Pauw, E., & De Pauw-Gillet, M.-C. (10 October 2007). Optoacoustic specific detection of prostate cancer using functionalized gold nanorods [Poster presentation]. Bioforum 2007.

Fleron, M., Schol, D., Greisch, J.-F., De Pauw, E., & De Pauw-Gillet, M.-C. (09 June 2007). Development of a new integrated biosensor system for an accurate diagnosis of prostate cancer using optoacoustic detection [Poster presentation]. Journées du CRCE, Liège, Belgium.

Fleron, M., Schol, D., Greisch, J.-F., De Pauw, E., & De Pauw-Gillet, M.-C. (21 March 2007). Overview on the ADONIS Project: Accurate Diagnosis of prostate cancer using Optoacoustic detection of biologically functionalized gold Nanoparticles - A new Integrated Biosensor System [Poster presentation]. Biomedica 2007, Aachen, Netherlands.

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