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Hulin Alexia

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Main Referenced Co-authors
Lancellotti, Patrizio  (7)
Colige, Alain  (6)
Oury, Cécile  (6)
Lambert, Charles  (5)
Radermecker, Marc  (5)
Main Referenced Keywords
Animals (4); Disease Models, Animal (3); Humans (3); Mice (3); Heart valve (2);
Main Referenced Unit & Research Centers
Giga-Cancer - ULiège (2)
GIGA - Cardiovascular Sciences (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (13)
Cardiovascular & respiratory systems (8)
Surgery (3)
Oncology (1)

Publications (total 22)

The most downloaded
6414 downloads
Radermecker, M., Boulanger, K., Hulin, A., Lambert, C., Limet, R., Lapière, C., & Nusgens, B. (2008). L'insuffisance mitrale par degenerescence myxoide: aspect biochimique et considerations physiopathologiques. Revue Médicale de Liège, 63 (4), 187-92. https://hdl.handle.net/2268/20650

The most cited

114 citations (OpenAlex)

Hulin, A., Hortells, L., Gomez-Stallons, M. V., O'Donnell, A., Chetal, K., Adam, M., Lancellotti, P., Oury, C., Potter, S. S., Salomonis, N., & Yutzey, K. E. (2019). Maturation of heart valve cell populations during postnatal remodeling. Development, 146 (12). doi:10.1242/dev.173047 https://hdl.handle.net/2268/235908

Ferreira Melo, S., Nondonfaz, A., Aqil, A., Pierrard, A., Hulin, A., Delierneux, C., Ditkowski, B., Gustin, M., Legrand, M., Tullemans, B. M. E., Brouns, S. L. N., Nchimi Longang, A., Carrus, R., Dejosé, A., Heemskerk, J. W. M., Kuijpers, M. J. E., Ritter, J., Steinseifer, U., Clauser, J. C., ... Oury, C. (2024). Design, manufacturing and testing of a green non-isocyanate polyurethane prosthetic heart valve. Biomaterials Science. doi:10.1039/d3bm01911j
Peer Reviewed verified by ORBi

Donis, N., Jiang, Z., D'Emal, C., Hulin, A., Debuisson, M., Dulgheru, R. E., Nguyen, M.-L., Postolache, A., LALLEMAND, F., COUCKE, P., Martinive, P., Herzog, M., Pamart, D., Terrell, J., Pincemail, J., Drion, P., DELVENNE, P., Nchimi Longang, A., LANCELLOTTI, P., & Oury, C. (28 February 2022). Differential Biological Effects of Dietary Lipids and Irradiation on the Aorta, Aortic Valve, and the Mitral Valve. Frontiers in Cardiovascular Medicine, 9, 1-16. doi:10.3389/fcvm.2022.839720
Peer Reviewed verified by ORBi

Oury, C., MARECHAL, P., Donis, N., Hulin, A., Hego, A., TRIDETTI, J., Nguyen, M.-L., DULGHERU, R. E., Fillet, M., Nchimi Longang, A., & Lancellotti, P. (2020). Dexfenfluramine and Pergolide Cause Heart Valve Disease via Valve Metabolic Reprogramming and Ongoing Matrix Remodeling. International Journal of Molecular Sciences, 21 (11). doi:10.3390/ijms21114003
Peer Reviewed verified by ORBi

Kim, A. J., Xu, N., Umeyama, K., Hulin, A., Ponny, S. R., Vagnozzi, R. J., Green, E. A., Hanson, P., McManus, B. M., Nagashima, H., & Yutzey, K. E. (2020). Deficiency of Circulating Monocytes Ameliorates the Progression of Myxomatous Valve Degeneration in Marfan Syndrome. Circulation, 132-146. doi:10.1161/CIRCULATIONAHA.119.042391
Peer Reviewed verified by ORBi

Donis, N., D'Emal, C., Hulin, A., Gustin, M., DULGHERU, R. E., LANCELLOTTI, P., & Oury, C. (22 November 2019). Platelets and aortic valve calcification: insights from a rabbit model and from patients with severe aortic stenosis [Paper presentation]. Belgian Working Group of Basic Research in Cardiology, Belgium.

Blomme, B.* , Deroanne, C.* , Hulin, A., Lambert, C., Defraigne, J.-O., Nusgens, B., Radermecker, M., & Colige, A. (20 August 2019). Mechanical strain induces a pro-fibrotic phenotype in human mitral valvular interstitial cells through RhoC/ROCK/MRTF-A and Erk1/2 signaling pathways. Journal of Molecular and Cellular Cardiology, 135, 149-159. doi:10.1016/j.yjmcc.2019.08.008
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Hulin, A., Hortells, L., Gomez-Stallons, M. V., O'Donnell, A., Chetal, K., Adam, M., Lancellotti, P., Oury, C., Potter, S. S., Salomonis, N., & Yutzey, K. E. (2019). Maturation of heart valve cell populations during postnatal remodeling. Development, 146 (12). doi:10.1242/dev.173047
Peer Reviewed verified by ORBi

Hulin, A., Hego, A., Lancellotti, P., & Oury, C. (2018). Advances in Pathophysiology of Calcific Aortic Valve Disease Propose Novel Molecular Therapeutic Targets. Frontiers in Cardiovascular Medicine, 5, 21. doi:10.3389/fcvm.2018.00021
Peer Reviewed verified by ORBi

Hulin, A., Potter, S., Kim, A., DeFalco, T., & Yutzey, K. E. (2017). Contribution of macrophages to myxomatous valve disease [Poster presentation]. Experimental Biology.

Hulin, A., Moore, V., James, J. M., & Yutzey, K. E. (2017). Loss of Axin2 results in impaired heart valve maturation and subsequent myxomatous valve disease. Cardiovascular Research, 113 (1), 40-51. doi:10.1093/cvr/cvw229
Peer Reviewed verified by ORBi

Hulin, A., & Yutzey, K. (2016). Loss of Axin2 leads to Myxomatous Valve Disease [Poster presentation]. Experimental Biology.

Deroyer, C., Magne, J., Moonen, M., Le Goff, C., Dupont, L., Hulin, A., Radermecker, M., Colige, A., Cavalier, E., Kolh, P., Pierard, L., LANCELLOTTI, P., Merville, M.-P., & Fillet, M. (2015). New biomarkers for primary mitral regurgitation. Clinical Proteomics, 12, 25. doi:10.1186/s12014-015-9097-2
Peer Reviewed verified by ORBi

Hulin, A., Alfieri, C. M., & Yutzey, K. E. (2015). Loss of axin2 in murine aortic valves leads to myxomatous disease [Poster presentation]. Experimental Biology.

Fang, M., Alfieri, C. M., Hulin, A., Conway, S. J., & Yutzey, K. E. (2014). Loss of beta-catenin promotes chondrogenic differentiation of aortic valve interstitial cells. Arteriosclerosis, Thrombosis and Vascular Biology, 34 (12), 2601-8. doi:10.1161/ATVBAHA.114.304579
Peer Reviewed verified by ORBi

Hulin, A., Cheek, J. D., Alfieri, C. M., Hinton, R., Colige, A., & Yutzey, K. (2014). Chondrogenic Pathways Involved In The Development of Myxomatous Valve Disease [Poster presentation]. Biennal Heart Valve Biology and Tissue Engineering Meeting.

Barnette, D., Hulin, A., Ahmed, I., Colige, A., Azhar, M., & LINCOLN, J. (December 2013). Tgfbeta-Smad and MAPK signaling mediate scleraxis and proteoglycan expression in heart valves. Journal of Molecular and Cellular Cardiology, 65, 137-146. doi:10.1016/j.yjmcc.2013.10.007
Peer Reviewed verified by ORBi

Hulin, A., Deroanne, C., Lambert, C., Defraigne, J.-O., Nusgens, B., RADERMECKER, M., & Colige, A. (2013). Emerging pathogenic mechanisms in human myxomatous mitral valve: lessons from past and novel data. Cardiovascular Pathology, 22 (4), 245-250. doi:10.1016/j.carpath.2012.11.001
Peer Reviewed verified by ORBi

Hulin, A. (2012). Etude des mécanismes pathogéniques impliqués dans la dégénérescence myxoïde de la valve mitrale [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315018

Hulin, A., Deroanne, C., Lambert, C., Dumont, B., Castronovo, V., Defraigne, J.-O., Nusgens, B., RADERMECKER, M., & Colige, A. (27 January 2012). Metallothionein-dependent up-regulation of TGF-B2 participates in the remodelling of the myxomatous mitral valve. Cardiovascular Research, 93 (3), 480-9.
Peer Reviewed verified by ORBi

Hulin, A. (2012). Etude des mécanismes pathogéniques impliqués dans la dégénérescence myxoïde de la valve mitrale [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/211237

Hulin, A., Lambert, C., Deroanne, C., Defraigne, J.-O., Nusgens, B., Colige, A., & RADERMECKER, M. (2011). Reduced expression of metallothioneins in myxomatous mitral valve prolapse andTGF-B2 signaling [Poster presentation]. Biennal Meeting of the Society for Heart Valve Disease, Barcelone, Spain.

Radermecker, M., Boulanger, K., Hulin, A., Lambert, C., Limet, R., Lapière, C., & Nusgens, B. (2008). L'insuffisance mitrale par degenerescence myxoide: aspect biochimique et considerations physiopathologiques. Revue Médicale de Liège, 63 (4), 187-92.
Peer reviewed

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