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Smargiasso Nicolas

Département de chimie (sciences) > Chimie analytique inorganique

See author's contact details
Main Referenced Co-authors
De Pauw, Edwin  (107)
Mazzucchelli, Gabriel  (53)
Baiwir, Dominique  (42)
Meuwis, Marie-Alice  (26)
Quinton, Loïc  (25)
Main Referenced Keywords
mass spectrometry (10); G-quadruplex (7); MALDI (6); Mass Spectrometry (6); Proteomics (5);
Main Referenced Unit & Research Centers
Giga-Systems Biology and Chemical Biology - ULiège [BE] (14)
CART - Centre Interfacultaire d'Analyse des Résidus en Traces - ULiège [BE] (7)
Laboratoire de Spectrométrie de Masse (4)
Laboratoire de gastro-entérologie translationnelle (3)
Centre d'Économie Rurale (Marloie) - CER (2)
Main Referenced Disciplines
Chemistry (60)
Biochemistry, biophysics & molecular biology (34)
Gastroenterology & hepatology (17)
Oncology (7)
Human health sciences: Multidisciplinary, general & others (3)

Publications (total 114)

The most downloaded
1352 downloads
Debois, D., Smargiasso, N., Demeure, K., Asakawa, D., Zimmerman, T., Quinton, L., & De Pauw, E. (2013). MALDI In-Source Decay, from sequencing to imaging. Topics in Current Chemistry, 331, 117-141. doi:10.1007/128_2012_363 https://hdl.handle.net/2268/133048

The most cited

242 citations (Scopus®)

Smargiasso, N., Rosu, F., Hsia, W., Colson, P., Baker, E. S., Bowers, M. T., De Pauw, E., & Gabelica, V. (2008). G-Quadruplex DNA Assemblies: Loop Length, Cation Identity, and Multimer Formation. Journal of the American Chemical Society, 130 (31), 10208-10216. doi:10.1021/ja801535e https://hdl.handle.net/2268/397

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pierre, N., Baiwir, D., Huynh-Thu, V. A., Mazzucchelli, G., Smargiasso, N., De Pauw, E., Bouhnik, Y., Laharie, D., Colombel, J.-F., Meuwis, M.-A., & Louis, E. (2021). Discovery of biomarker candidates associated with the risk of short-term and mid/long-term relapse after infliximab withdrawal in Crohn's patients: a proteomics-based study. Gut. doi:10.1136/gutjnl-2020-322100
Peer Reviewed verified by ORBi

Ait Kaki, A., Smargiasso, N., Ongena, M., Kara Ali, M., Moula, N., De Pauw, E., & Kacem Chaouche, N. (2020). Characterization of New Fengycin Cyclic Lipopeptide Variants Produced by Bacillus amyloliquefaciens (ET) Originating from a Salt Lake of Eastern Algeria. Current Microbiology. doi:10.1007/s00284-019-01855-w
Peer Reviewed verified by ORBi

Morsa, D., Baiwir, D., La Rocca, R., Zimmerman, T. A., Hanozin, E., Grifnée, E., Longuespée, R., Meuwis, M.-A., Smargiasso, N., De Pauw, E., & Mazzucchelli, G. (2019). Multi-Enzymatic Limited Digestion: The Next-Generation Sequencing for Proteomics? Journal of Proteome Research. doi:10.1021/acs.jproteome.9b00044
Peer Reviewed verified by ORBi

Chevalier, M., Ricart, E., Hanozin, E., Pupin, M., Jacques, P., Smargiasso, N., De Pauw, E., Lisacek, F., Leclère, V., & Flahaut, C. (2019). Kendrick Mass Defect Approach Combined to NORINE Database for Molecular Formula Assignment of Nonribosomal Peptides. Journal of the American Society for Mass Spectrometry, 30 (12), 2608-2616. doi:10.1007/s13361-019-02314-3
Peer Reviewed verified by ORBi

Pottier, C., Kriegsmann, M., Alberts, D., Smargiasso, N., Baiwir, D., Mazzucchelli, G., Herfs, M., Fresnais, M., Casadonte, R., Delvenne, P., De Pauw, E., & Longuespée, R. (2019). Microproteomic Profiling of High-Grade Squamous Intraepithelial Lesion of the Cervix: Insight into Biological Mechanisms of Dysplasia and New Potential Diagnostic Markers. Proteomics. Clinical Applications, 13(1). doi:10.1002/prca.201800052
Peer Reviewed verified by ORBi

Pierre, N., Salee, C., MASSOT, C., BLETARD, N., Mazzucchelli, G., Smargiasso, N., Morsa, D., Baiwir, D., De Pauw, E., REENAERS, C., VAN KEMSEKE, C., LOLY, J.-P., Delvenne, P., Meuwis, M.-A., & Louis, E. (2019). Proteomics highlights common and distinct pathophysiological processes associated with ileal and colonic ulcers in Crohn's disease. Journal of Crohn's & colitis. doi:10.1093/ecco-jcc/jjz130
Peer reviewed

Martinet, L., Naomé, A., Deflandre, B., Maciejewska, M., Tellatin, D., Tenconi, E., Smargiasso, N., De Pauw, E., van Wezel, G. P., & Rigali, S. (2019). A Single Biosynthetic Gene Cluster Is Responsible for the Production of Bagremycin Antibiotics and Ferroverdin Iron Chelators. MBio, 10 (4). doi:10.1128/mBio.01230-19
Peer Reviewed verified by ORBi

Pottier, C., Kriegsmann, M., Smargiasso, N., Baiwir, D., Mazzucchelli, G., Casadonte, R., De Pauw, E., & Longuespée, R. (06 June 2018). Microproteomic profiling og high-grade squamous intraepithelial lesions of the cervix [Poster presentation]. 66th Conference on Mass Spectrometry and Allied Topics, San Diego, United States.

Bafort, F., Damblon, C., Lognay, G., Barthelemy, J.-P., Smargiasso, N., Perraudin, J.-P., & Jijakli, H. (May 2018). BIOACTIVITY AND UNEXPECTED INTERHALOGEN PRODUCTION BY THE LACTOPEROXIDASE SYSTEM [Paper presentation]. 70th International Symposium on Crop Protection, Ghent, Belgium.

Massonnet, P., Kriegsmann, M., Smargiasso, N., Bertrand, V., & De Pauw, E. (29 March 2018). Small molecule analysis on FFPE-TMA samples using MALDI-mass spectrometry imaging [Poster presentation]. 2018 BSMS annual meeting.

Pierre, N., REENAERS, C., VAN KEMSEKE, C., LOLY, J.-P., Mazzucchelli, G., Smargiasso, N., Baiwir, D., Morsa, D., De Pauw, E., MEUWIS, M.-A., & Louis, E. (2018). Proteomic analysis highlights divergences and convergences between ileal and colonic pathological processes involved in Crohn’s ulcers. Journal of Crohn's and Colitis. doi:10.1093/ecco-jcc/jjx180.184
Peer Reviewed verified by ORBi

Pierre, N., REENAERS, C., VAN KEMSEKE, C., LOLY, J.-P., Mazzucchelli, G., Smargiasso, N., Baiwir, D., De Pauw, E., MEUWIS, M.-A., & LOUIS, E. (February 2018). Proteomic analysis highlights divergences and convergences between ileal and colonic pathological processes involved in Crohn’s ulcers [Poster presentation]. 30th edition of the Belgian Week of Gastroenterology, Anvers, Belgium.

Merli, A.-M., MASSOT, C., BLETARD, N., QUESADA-CALVO, F., Baiwir, D., Mazzucchelli, G., Smargiasso, N., Servais, L., Oury, C., De Pauw-Gillet, M.-C., De Pauw, E., COIMBRA MARQUES, C., Colard, A., Vijverman, A., DELVENNE, P., MEUWIS, M.-A., & LOUIS, E. (February 2018). Potential diagnostic biomarkers of Ulcerative colitis-associated colorectal dysplasia [Paper presentation]. 13th congress of European Crohn's and Colitis Organisation, Vienne, Austria.

Merli, A.-M., MASSOT, C., BLETARD, N., QUESADA-CALVO, F., Baiwir, D., Mazzucchelli, G., Smargiasso, N., Servais, L., Oury, C., De Pauw-Gillet, M.-C., De Pauw, E., COIMBRA MARQUES, C., Colard, A., Vijverman, A., DELVENNE, P., MEUWIS, M.-A., & LOUIS, E. (27 January 2018). Potential diagnostic biomarkers of Ulcerative Colitis-associated colorectal dysplasia [Poster presentation]. Belgian Association for Cancer Research Annual Meeting 2018, Liège, Belgium.

Bafort, F., Damblon, C., Smargiasso, N., De Pauw, E., Perraudin, J.-P., & Jijakli, H. (2018). Reaction product variability and biological activity of the lactoperoxidase system depending on medium ionic strength and pH, and on substrate relative concentration. Chemistry and Biodiversity, 15, 1700497. doi:10.1002/cbdv.201700497
Peer Reviewed verified by ORBi

Merli, A.-M., MASSOT, C., BLETARD, N., QUESADA-CALVO, F., Baiwir, D., Mazzucchelli, G., Smargiasso, N., Servais, L., Oury, C., De Pauw-Gillet, M.-C., De Pauw, E., COIMBRA MARQUES, C., Colard, A., Vijverman, A., DELVENNE, P., MEUWIS, M.-A., & LOUIS, E. (2018). Potential diagnostic biomarkers of Ulcerative colitis-associated colorectal dysplasia. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Alberts, D., POTTIER, C., Smargiasso, N., Baiwir, D., Mazzucchelli, G., Delvenne, P., Kriegsmann, M., Kazdal, D., Warth, A., De Pauw, E., & Longuespée, R. (January 2018). MALDI Imaging-Guided Microproteomic Analyses of Heterogeneous Breast Tumors-A Pilot Study. Proteomics. Clinical Applications, 12. doi:10.1002/prca.201700062
Peer Reviewed verified by ORBi

Grifnée, E., Hanozin, E., Smargiasso, N., Quinton, L., Mazzucchelli, G., & De Pauw, E. (2018). Structural characterization of proteins based on a homemade enzymatic reactor [Poster presentation]. BSMS.

Dubiela, P., Kabasser, S., Smargiasso, N., Geiselhart, S., Bublin, M., Hafner, C., Mazzucchelli, G., & Hoffmann-Sommergruber, K. (2018). Jug r 6 is the allergenic vicilin present in walnut responsible for IgE cross-reactivities to other tree nuts and seeds. Scientific Reports, 8 (1). doi:10.1038/s41598-018-29656-4
Peer Reviewed verified by ORBi

Harris, L. M., Monsell, K. R., Noulin, F., Toyin Famodimu, M., Smargiasso, N., Damblon, C., Horrocks, P., & Merrick, C. J. (2018). G-quadruplex DNA motifs in the malaria parasite plasmodium falciparum and their potential as novel antimalarial drug targets. Antimicrobial Agents and Chemotherapy, 62 (3). doi:10.1128/AAC.01828-17
Peer Reviewed verified by ORBi

Longuespée, R., Baiwir, D., Mazzucchelli, G., Smargiasso, N., & De Pauw, E. (2018). Laser Microdissection-Based Microproteomics of Formalin-Fixed and Paraffin-Embedded (FFPE) Tissues. Methods in Molecular Biology, 1723, 19 - 31. doi:10.1007/978-1-4939-7558-7_2
Peer Reviewed verified by ORBi

Massonnet, P., Haler, J., Uper, G., Smargiasso, N., Mourier, G., Gilles, N., Quinton, L., & De Pauw, E. (2018). Disulfide Connectivity Analysis of Peptides Bearing Two Intramolecular Disulfide Bonds Using MALDI In-Source Decay. Journal of the American Society for Mass Spectrometry, 29 (10), 1995-2002. doi:10.1007/s13361-018-2022-y
Peer Reviewed verified by ORBi

Baiwir, D., Nanni, P., Müller, S., Smargiasso, N., Morsa, D., De Pauw, E., & Mazzucchelli, G. (2018). Gel-free proteomics. In A. M. de Almeida, D. Eckersal, ... I. Miller (Eds.), Proteomics in Domestic Ani-mals: from Farm to Systems Biology. Springer, Cham. doi:10.1007/978-3-319-69682-9_5
Peer reviewed

Degueldre, M., Echterbille, J., Smargiasso, N., Damblon, C., Gouin, C., Mourier, G., Gilles, N., De Pauw, E., & Quinton, L. (18 November 2017). In-depth glyco-peptidomics approach reveals unexpected diversity of glycosylated peptides and atypical post-translational modifications in dendroaspis angusticeps snake venom. International Journal of Molecular Sciences, 18 (11), 2483. doi:10.3390/ijms18112453
Peer Reviewed verified by ORBi

Navarre, C.* , Smargiasso, N.* , Duvivier, L., Nader, J., Far, J., De Pauw, E., & Boutry, M. (June 2017). N-Glycosylation of an IgG antibody secreted by Nicotiana tabacum BY-2 cells can be modulated through co-expression of human β-1,4-galactosyltransferase. Transgenic Research, 26 (3), 375-384. doi:10.1007/s11248-017-0013-6
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Martinet, L., Maciejewska, M., Adam, D., Naomé, A., Carnol, M., Barton, H., Smargiasso, N., De Pauw, E., Hanikenne, M., Baurain, D., & Rigali, S. (24 May 2017). Streptomyces from Moonmilk, an Untapped Source of New Bioactive Compounds [Poster presentation]. International symposium on the biology of Actinomycetes, Jeju, South Korea.

QUESADA-CALVO, F., MASSOT, C., Bertrand, V., Longuespée, R., BLETARD, N., SOMJA, J., Mazzucchelli, G., Smargiasso, N., Baiwir, D., De Pauw-Gillet, M.-C., Delvenne, P., MALAISE, M., COIMBRA MARQUES, C., POLUS, M., De Pauw, E., MEUWIS, M.-A., & Louis, E. (24 March 2017). OLFM4, KNG1 and Sec24C identified by proteomics and immunohistochemistry as potential markers of early colorectal cancer stages. Clinical Proteomics, 24 (9). doi:10.1186/s12014-017-9143-3
Peer Reviewed verified by ORBi

Mercx, S., Smargiasso, N., Chaumont, F., De Pauw, E., Boutry, M., & Navarre, C. (March 2017). Inactivation of the β(1,2)-xylosyltransferase and the α(1,3)-fucosyltransferase genes in Nicotiana tabacum BY-2 cells by a multiplex CRISPR/Cas9 strategy results in glycoproteins without plant-specific glycans. Frontiers in Plant Science, 8. doi:10.3389/fpls.2017.00403
Peer Reviewed verified by ORBi

QUESADA-CALVO, F., Merli, A.-M., MASSOT, C., BLETARD, N., SOMJA, J., Smargiasso, N., Baiwir, D., Mazzucchelli, G., De Pauw-Gillet, M.-C., COIMBRA MARQUES, C., POLUS, M., MALAISE, M., De Pauw, E., DELVENNE, P., MEUWIS, M.-A., & LOUIS, E. (10 February 2017). Proteomic differential distribution of 53BP1 in serrated and conventional adenomas validated by histological characterisation [Poster presentation]. Belgian week of Gastroenterology, Anvers, Belgium.

Merli, A.-M., QUESADA-CALVO, F., MASSOT, C., BLETARD, N., Smargiasso, N., Baiwir, D., Mazzucchelli, G., De Pauw-Gillet, M.-C., MALAISE, M., De Pauw, E., DELVENNE, P., Meuwis, M.-A., & Louis, E. (09 February 2017). Identification of proteins discriminating inflammation induced dysplasia from simple inflammation in ulcerative colitis by laser capture microdissection and label free proteomics – a pilot study [Paper presentation]. XXIXth edition of the Belgian Week of Gastroenterology, Anvers, Belgium.

Merli, A.-M., QUESADA-CALVO, F., MASSOT, C., BLETARD, N., Smargiasso, N., Baiwir, D., Mazzucchelli, G., De Pauw-Gillet, M.-C., MALAISE, M., De Pauw, E., DELVENNE, P., Meuwis, M.-A., & Louis, E. (01 February 2017). Identification of proteins discriminating inflammation induced dysplasia from simple inflammation in ulcerative colitis by laser capture microdissection and label free proteomics – a pilot study [Poster presentation]. GIGA DAY 2017, Liège, Belgium.

Herfs, M., Longuespée, R., Quick, C., RONCARATI, P., Suarez-Carmona, M., Hubert, P., Lebeau, A., Bruyère, D., Mazzucchelli, G., Smargiasso, N., Baiwir, D., Lai, K., Dunn, A., Obregon, F., Yang, E., De Pauw, E., Crum, C., & Delvenne, P. (2017). Proteomic signatures reveal a dualistic and clinically relevant classification of anal canal carcinoma. Journal of Pathology, 241, 522-533. doi:10.1002/path.4858
Peer Reviewed verified by ORBi

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Scheijen, J., Schalkwijk, C., Leenders, J., De Tullio, P., BIANCHI, E., Thiry, M., Uchida, K., Spiegel, D., Cochrane, J., ... Bellahcene, A. (2016). Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP- mediated tumor growth and metastasis. eLife. doi:10.7554/eLife.19375
Peer Reviewed verified by ORBi

Maciejewska, M.* , Adam, D.* , Martinet, L., Naomé, A., Całusińska, M., Delfosse, P., Carnol, M., Barton, H., HAYETTE, M.-P., Smargiasso, N., De Pauw, E., Hanikenne, M., Baurain, D., & Rigali, S. (2016). A Phenotypic and Genotypic Analysis of the Antimicrobial Potential of Cultivable Streptomyces Isolated from Cave Moonmilk Deposits. Frontiers in Microbiology. doi:10.3389/fmicb.2016.01455
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Abboud, M., Damblon, C., Brem, J., Smargiasso, N., Mercuri, P., Gilbert, B., Rydzik, A., Claridge, T., Schofield, C., & Frère, J.-M. (September 2016). Interaction of Avibactam with Class B Metallo-β-Lactamases. Antimicrobial Agents and Chemotherapy, 60, 5655-6. doi:10.1128/AAC.00897-16
Peer Reviewed verified by ORBi

Alberts, D., Longuespée, R., Smargiasso, N., Mazzucchelli, G., Baiwir, D., DELVENNE, P., Pamelard, F., Picard de Meller, G., & De Pauw, E. (09 June 2016). MALDI-imaging guided microproteomics workflow for biomarker discovery of intra-tumor heterogeneity [Poster presentation]. 64th Conference on Mass Spectrometry and Allied Topics, San Antionio, Texas, United States.

Smargiasso, N., Far, J., Navarre, C., Opsomer, E., Mazzucchelli, G., Baiwir, D., Boutry, M., & De Pauw, E. (07 June 2016). N-Glycoproteomic characterization of recombinant Human cytomegalovirus Glycoprotein B using multienzymatic proteolysis coupled to LC-MS/MS and CZE-MS/MS [Poster presentation]. 64th ASMS Conference on Mass Spectrometry and Allied Topics, San Antonio, TX, United States.

QUESADA-CALVO, F., Meuwis, M.-A., Bertrand, V., Longuespée, R., BLETARD, N., SOMJA, J., Mazzucchelli, G., Smargiasso, N., Baiwir, D., De Pauw-Gillet, M.-C., Delvenne, P., Malaise, M., COIMBRA MARQUES, C., POLUS, M., De Pauw, E., & Louis, E. (19 February 2016). Proteins in early CRC stages - from proteomic discovery to immunohistochemistry tissue distribution characterisation [Poster presentation]. Belgian Week of Gastroenterology, Bruxelles, Belgium.

Mazzucchelli, G., Zimmerman, T., Smargiasso, N., Baiwir, D., MEUWIS, M.-A., & De Pauw, E. (22 January 2016). De novo sequencing using MELD proteolysis coupled to a "sequence assembly" algorithm [Poster presentation]. 28th Sanibel Conference on Mass Spectrometry: Characterization of Protein Therapeutics by Mass Spectrometry, Clearwater Beach, United States - Florida.

Bekhouche, M., Leduc, C., Dupont, L., Janssen, L., Delolme, F., Vadon-Le Goff, S., Smargiasso, N., Baiwir, D., Mazzucchelli, G., Zanella-Cleon, I., Dubail, J., De Pauw, E., Nusgens, B., Hulmes, D., Moali, C., & Colige, A. (06 January 2016). Determination of the substrate repertoire of ADAMTS2, 3 and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-beta signaling as primary targets. FASEB Journal, 5, 1741-56. doi:10.1096/fj.15-279869
Peer Reviewed verified by ORBi

Longuespée, R., Alberts, D., Pottier, C., Smargiasso, N., Mazzucchelli, G., Baiwir, D., Kriegsmann, M., Herfs, M., Kriegsmann, J., Delvenne, P., & De Pauw, E. (2016). A laser microdissection-based workflow for FFPE tissue microproteomics: important considerations for small sample processing. Methods, 104, 154-162. doi:10.1016/j.ymeth.2015.12.008
Peer Reviewed verified by ORBi

Massonnet, P., Haler, J., Upert, G., Degueldre, M., Morsa, D., Smargiasso, N., Mourier, G., Gilles, N., Quinton, L., & De Pauw, E. (2016). Ion Mobility-Mass Spectrometry as a Tool for the Structural Characterization of Peptides Bearing Intramolecular Disulfide Bond(s). Journal of the American Society for Mass Spectrometry, 27 (10), 1637–1646. doi:10.1007/s13361-016-1443-8
Peer Reviewed verified by ORBi

Walski, T., Van Damme, E., Smargiasso, N., Christiaens, O., De Pauw, E., & Smagghe, G. (2016). Protein N-glycosylation and N-glycan trimming are required for postembryonic development of the pest beetle Tribolium castaneum. Scientific Reports. doi:10.1038/srep35151
Peer Reviewed verified by ORBi

Jadoul, L., Smargiasso, N., Pamelard, F., Alberts, D., Noël, A., De Pauw, E., & Longuespée, R. (2016). An Improved Molecular Histology Method for Ion Suppression Monitoring and Quantification of Phosphatidyl Cholines During MALDI MSI Lipidomics Analyses. OMICS: A Journal of Integrative Biology, 20 (2), 110-21. doi:10.1089/omi.2015.0165
Peer Reviewed verified by ORBi

Baiwir, D., Mazzucchelli, G., Smargiasso, N., QUESADA CALVO, F., De Pauw, E., MALAISE, M., Louis, E., & MEUWIS, M.-A. (December 2015). Comparison of serum fractionation methods by data independent label-free proteomics. EuPA Open Proteomics, 9, 14-22. doi:10.1016/j.euprot.2015.07.009
Peer Reviewed verified by ORBi

QUESADA-CALVO, F., Meuwis, M.-A., Bertrand, V., Longuespée, R., BLETARD, N., Somja, J., Mazzucchelli, G., Smargiasso, N., Baiwir, D., De Pauw-Gillet, M.-C., Delvenne, P., Malaise, M., POLUS, M., De Pauw, E., & Louis, E. (27 October 2015). LABEL FREE PROTEOMICS IDENTIFIES OLFACTOMEDIN-4 AS A MARKER OF EPITHELIAL TRANSITION OF EARLY CRC STAGES [Paper presentation]. UEG Week Barcelona 2015, Barcelona, Spain.

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Turtoi, A., Costanza, B., Smargiasso, N., Baiwir, D., Leenders, J., De Tullio, P., BIANCHI, E., Thiry, M., Uchida, K., Spiegel, D., Cochrane, J., Hutton, C., De Pauw, E., ... Bellahcene, A. (29 September 2015). Methylglyoxal, a glycolysis side-product, induces Hsp90 post-translational glycation and YAP-mediated breast tumor growth and metastasis [Poster presentation]. Cancer and Metabolism Conference, Cambridge, United Kingdom.

Massonnet, P., Upert, G., Haler, J., Degueldre, M., Morsa, D., Smargiasso, N., Gilles, N., Quinton, L., & De Pauw, E. (18 September 2015). New methodology using Ion Mobility Mass Spectrometry for structural characterization and cysteine connectivity identification of peptides bearing intra-molecular disulfide bonds [Paper presentation]. 2015 BSMS annual meeting, Brussels, Belgium.

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Peulen, O., Blomme, A., Smargiasso, N., De Tullio, P., BIANCHI, E., Baiwir, D., Thiry, M., Turtoi, A., De Pauw, E., DELVENNE, P., Castronovo, V., & Bellahcene, A. (09 September 2015). Methylglyoxal, a glycolysis side-product, induces Hsp90 post-translational glycation and YAP-mediated breast tumor growth and metastasis [Poster presentation]. Metabolism in Cancer and Stromal Cells, Leuven, Belgium.

Massonnet, P., Upert, G., Haler, J., Degueldre, M., Morsa, D., Smargiasso, N., Gilles, N., Quinton, L., & De Pauw, E. (03 June 2015). Ion mobility mass spectrometry as a tool to perform structural characterization of peptides bearing disulfide bond(s) [Poster presentation]. 63rd ASMS Conference on Mass Spectrometry and Allied Topics, St Louis, United States - Missouri.

Smargiasso, N., Walski, T., Van Damme, E., De Pauw, E., & Smagghe, G. (June 2015). Study of N-linked glycosylation in different life stages of the red flour beetle (Tribolium castaneum) [Poster presentation]. 63rd ASMS Conference on Mass Spectrometry and Allied Topics, St Louis, United States.

Mazzucchelli, G., Zimmerman, T., Smargiasso, N., Baiwir, D., MEUWIS, M.-A., & De Pauw, E. (2015). De novo sequencing using MELD proteolysis coupled to a "sequence assembly" algorithm. In 63rd ASMS Conference Proceedings, May 30 - June 4 2015, St. Louis, MO.
Peer reviewed

QUESADA CALVO, F., MEUWIS, M.-A., Bertrand, V., Longuespée, R., SOMJA, J., Mazzucchelli, G., Smargiasso, N., Baiwir, D., Delvenne, P., MALAISE, M., POLUS, M., De Pauw-Gillet, M.-C., De Pauw, E., & Louis, E. (2015). Comparison of early stages of colorectal cancer by label free proteomics. In Acta Gastroenterologica.
Peer reviewed

MEUWIS, M.-A., QUESADA CALVO, F., Baiwir, D., Mazzucchelli, G., Smargiasso, N., De Pauw, E., MALAISE, M., GETAID, & LOUIS, E. (2015). Potential Proteomic Biomarkers Associated with Mucosal Healing and Relapse Prediction after IFX Withdrawals in Crohn’s Disease. In Acta gastroenterologica.
Peer reviewed

Nokin, M.-J., Durieux, F., Peixoto, P., Chiavarina, B., Smargiasso, N., Baiwir, D., De Pauw, E., De Tullio, P., Thiry, M., Peulen, O., Turtoi, A., Castronovo, V., & Bellahcene, A. (27 January 2015). Accumulation of methylglyoxal, a glycolysis by-product modulates YAP1 transcription co-factor localization and activity in human breast cancer cells through HSP90 modification [Poster presentation]. GIGA-DAY: Current advances in medical genetics and genomics, Liège, Belgium.

Grifnée, E., Mazzucchelli, G., Smargiasso, N., & De Pauw, E. (2015). Study of residual protein structure during enzymatic digestion by ion mobility mass spectrometry [Poster presentation]. SSP Halle.

Massonnet, P., Upert, G., Smargiasso, N., Gilles, N., Quinton, L., & De Pauw, E. (2015). Combined use of Ion Mobility and Collision-Induced Dissociation to investigate the opening of disulfide bridges by Electron-Transfer Dissociation in peptides bearing two disulfide bonds. Analytical Chemistry, 87 (10), 5240–5246. doi:10.1021/acs.analchem.5b00245
Peer Reviewed verified by ORBi

Massonnet, P., Upert, G., Morsa, D., Smargiasso, N., Gilles, N., Quinton, L., & De Pauw, E. (November 2014). Ion mobility-mass spectrometry to perform structural classifications of disulfide-bridged-peptides [Poster presentation]. Annual meeting of the Belgian Society for Mass Spectrometry (BSMS), Wavre, Belgium.

Massonnet, P., Upert, G., Morsa, D., Smargiasso, N., Gilles, N., Quinton, L., & De Pauw, E. (November 2014). Ion mobility-mass spectrometry to perform structural classifications of disulfide-bridged-peptides [Poster presentation]. Symposium on structural proteomic 2014, Anvers, Belgium.

Grifnée, E., Mazzucchelli, G., Smargiasso, N., & De Pauw, E. (November 2014). Structural characterization of protein using an enzymatic reactor [Poster presentation]. SSP 2014.

MEUWIS, M.-A., Baiwir, D., Mazzucchelli, G., Smargiasso, N., Quesada-Calvo, F., MALAISE, M., De Pauw, E., The GETAID, & LOUIS, E. (06 October 2014). Potential Proteomic Biomarkers Associated To Mucosal Healing In Crohn’s Disease [Poster presentation]. HUPO2014, Madrid, Spain.

Baiwir, D., Mazzucchelli, G., Smargiasso, N., & De Pauw, E. (06 October 2014). SRM Vs HR-MS quantitative proteomics: matrix effect and LOQ in serum [Poster presentation]. 13th Human Proteome Organization World Congress.

Asakawa, D., Smargiasso, N., & De Pauw, E. (29 September 2014). Coordination of alkali metal ions to model branched hexasaccharides dictates fragment yield in MALDI in-source decay with hydrogen abstraction using 5-nitrosalicylic acid as the matrix. Journal of Mass Spectrometry, 49, 1059-1062. doi:10.1002/jms.3415
Peer Reviewed verified by ORBi

Baiwir, D., Mazzucchelli, G., Smargiasso, N., & De Pauw, E. (17 June 2014). SRM Vs HR-MS quantitative proteomics: matrix effect and LOQ in serum [Poster presentation]. 62nd ASMS Conference on Mass Spectrometry and Allied Topics, Baltimore, United States.

Debois, D., Jourdan, E., Smargiasso, N., Thonart, P., De Pauw, E., & Ongena, M. (May 2014). Spatiotemporal monitoring of the antibiome secreted by Bacillus biofilms on plant roots using MALDI mass spectrometry imaging. Analytical Chemistry, 86 (9), 4431-4438. doi:10.1021/ac500290s
Peer Reviewed verified by ORBi

Debois, D., Smargiasso, N., Jourdan, E., Calligaris, D., Thonart, P., Ongena, M., & De Pauw, E. (04 April 2014). Imaging MS: strategies for the identification of analytes [Paper presentation]. Jounrée scientifique: L'imagerie par spectrométrie de masse : principes, intérêts et limites, Toulouse, France.

Massonnet, P., Upert, G., Pastor, A., Smargiasso, N., Gilles, N., Quinton, L., & De Pauw, E. (April 2014). Combined use of Ion Mobility and Collision-Induced Dissociation (CID) to investigate the reactivity of disulfide-bridged peptides in Electron Transfer Dissociation (ETD) [Poster presentation]. 11th Uppsala Conference (UppCon) on Electron Capture and Transfer Dissociation, Obergurgl, Austria.

Massonnet, P., Uper, G., Pastor, A., Smargiasso, N., Gilles, N., Quinton, L., & De Pauw, E. (January 2014). Combined use of Ion Mobility and Collision-Induced Dissociation (CID) to investigate the reactivity of disulfide-bridged peptides in Electron Transfer Dissociation (ETD) [Poster presentation]. 2014 Sanibel conference on "Ion Activation: Fundamentals, Applications and New Frontiers", Clearwater Beach, United States - Florida.

QUESADA CALVO, F., Bertrand, V., Longuespée, R., Delga, A., Mazzucchelli, G., Smargiasso, N., Baiwir, D., Delvenne, P., MALAISE, M., De Pauw-Gillet, M.-C., De Pauw, E., Louis, E., & Meuwis, M.-A. (2014). Comparison of two FFPE preparation methods using label-free shotgun proteomics: Application to tissues of diverticulitis patients. Journal of Proteomics, 112C, 250-261. doi:10.1016/j.jprot.2014.08.013
Peer Reviewed verified by ORBi

Longuespée, R., Pottier, C., Smargiasso, N., Mazzucchelli, G., Alberts, D., Baiwir, D., DELVENNE, P., & De Pauw, E. (2014). Downscalling tissue proteomics: analyses of limited amounts of FFPE tissue samples. Application to cervix cancer biomarker markers [Poster presentation]. Meeting of Belgian Society for Mass Spectrometry, Wavre, Belgium.

Longuespée, R., Fléron, M., Pottier, C., QUESADA CALVO, F., Meuwis, M.-A., Baiwir, D., Smargiasso, N., Mazzucchelli, G., De Pauw-Gillet, M.-C., Delvenne, P., & De Pauw, E. (2014). Tissue Proteomics for the Next Decade? Towards a Molecular Dimension in Histology. OMICS: A Journal of Integrative Biology. doi:10.1089/omi.2014.0033
Peer Reviewed verified by ORBi

Czerwinska, I., Mazzucchelli, G., Smargiasso, N., Riou, J.-F., De Pauw-Gillet, M.-C., & De Pauw, E. (2014). Development of an approach for analyzing the telomere interacting proteins [Poster presentation]. From analytical to functional proteomics.

Asakawa, D., Smargiasso, N., Quinton, L., & De Pauw, E. (2014). Influences of proline and cysteine residues on fragment yield in matrix-assisted laser desorption/ionization in-source decay mass spectrometry. Journal of the American Society for Mass Spectrometry. doi:10.1007/s13361-014-0868-1
Peer Reviewed verified by ORBi

Asakawa, D., Smargiasso, N., & De Pauw, E. (2014). New approach for pseudo-MS3 analysis of peptides and proteins via MALDI in-source decay using radical recombination with 1,5- diaminonaphthalene. Analytical Chemistry. doi:10.1021/ac403285b
Peer Reviewed verified by ORBi

Smargiasso, N., Mazzucchelli, G., Baiwir, D., LOUIS, E., Quesada-Calvo, F., MEUWIS, M.-A., & De Pauw, E. (2014). Data dependent versus Data independent acquisition applied to samples with different protein dynamic range [Poster presentation]. 13th Human Proteome Organization World Congress.

Herman, J., Thelen, N., Smargiasso, N., Mailleux, A.-C., Luxen, A., Cloes, M., De Pauw, E., Chevigné, A., Galleni, M., & Dumez, M.-E. (2014). Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus. Biochimica et Biophysica Acta - General Subjects, 1840 (3), 1117–1124. doi:10.1016/j.bbagen.2013.11.017
Peer Reviewed verified by ORBi

Czerwinska, I., Badiola, A., Smargiasso, N., & De Pauw, E. (2014). Use of ion mobility mass spectrometry to study the small organometallic complexes [Poster presentation]. Mass Spectrometry of Biomolecules and its Applications in the Biopharmaceutical Industry.

Debois, D., Jourdan, E., Cawoy, H., Smargiasso, N., Thonart, P., Ongena, M., & De Pauw, E. (05 December 2013). Tandem MS of -new- antibiotics from Bacillus guided by MALDI Mass Spectrometry Imaging [Paper presentation]. 26th Workshop on Tandem Mass Spectrometry, Lake Louise, AB, Canada.

Quinton, L., Massonnet, P., Echterbille, J., Degueldre, M., Smargiasso, N., Gilles, N., Upert, G., Pastor, A., & De Pauw, E. (December 2013). Attribution of Cysteine Connectivities in small toxins - New Prospects Based on Partial Oxidation/Reduction Experiments and Ion-Mobility Mass Spectrometry [Paper presentation]. 21st Meeting of the French Society for Toxinology: “Fresh water and Marine Toxins”.

Massonnet, P., Echterbille, J., Upert, G., Pastor, A., Smargiasso, N., Gilles, N., Quinton, L., & De Pauw, E. (15 November 2013). Combined use of mass spectrometry techniques for cysteine connectivity identification for peptides bearing 2 disulfide bonds [Paper presentation]. SFMBBM doctoral school day (FNRS).

Massonnet, P., Upert, G., Pastor, A., Smargiasso, N., Quinton, L., Gilles, N., & De Pauw, E. (05 September 2013). Structural characterization of disulfide-bridged-peptides by a combined use of ETD, CID and Ion-Mobility mass spectrometry [Paper presentation]. Chemistry Department Day.

Lemaire, P., Debois, D., Smargiasso, N., Quinton, L., Gabelica, V., & De Pauw, E. (August 2013). Use of 1,5-diaminonaphthalene to combine matrix-assisted laser desorption/ionization in-source decay fragmentation with hydrogen/deuterium exchange. Rapid Communications in Mass Spectrometry, 27 (16), 1837-1846. doi:10.1002/rcm.6627
Peer Reviewed verified by ORBi

Debois, D., Jourdan, E., Smargiasso, N., Ongena, M., & De Pauw, E. (12 June 2013). Distribution and identification of molecular interactions between tomato roots and bacterial biofilms [Poster presentation]. 61st ASMS Conference on Mass Spectrometry and Allied Topics, Minneapolis, United States - Minnesota.

Massonnet, P., Quinton, L., Smargiasso, N., Upert, G., Pastor, A., Gilles, N., & De Pauw, E. (11 June 2013). Structural characterization of disulfide-bridged-peptides by a combined use of ETD and Ion-Mobility mass spectrometry [Poster presentation]. 61st ASMS Conference on Mass Spectrometry and Allied Topics, Minneapolis, United States - Minnesota.

Degueldre, M., Quinton, L., Smargiasso, N., Mazzucchelli, G., Escoubas, P., Opsomer, E., Vandewalle, N., & De Pauw, E. (June 2013). ISD high-throughput platform for the sequencing of animal toxins [Poster presentation]. Annual congress of the American society for mass spectrometry.

Longuespée, R., Mazzucchelli, G., Calligaris, D., Smargiasso, N., Meuwis, M.-A., Delvenne, P., & De Pauw, E. (June 2013). Tissue preparations for low scale proteomics of microdissected samples or on-slides sections [Poster presentation]. American Society of Mass Spectrometry (ASMS) Conference, Minneapolis, United States.

Massonnet, P., Quinton, L., Smargiasso, N., Gilles, N., & De Pauw, E. (03 May 2013). Structural characterization of disulfide-bridged-peptides by a combined use of ETD and Ion-Mobility mass spectrometry [Poster presentation]. Annual meeting of the Belgian Society for Mass Spectrometry (BSMS), Anvers, Belgium.

Asakawa, D., Smargiasso, N., & De Pauw, E. (February 2013). Discrimination of Isobaric Leu/Ile Residues by MALDI In-source Decay Mass Spectrometry. Journal of the American Society for Mass Spectrometry, 24 (2), 297-300. doi:10.1007/s13361-012-0523-7
Peer Reviewed verified by ORBi

Asakawa, D., Calligaris, D., Smargiasso, N., & De Pauw, E. (29 January 2013). Ultraviolet Laser Induced Hydrogen Transfer Reaction: Study of the First Step of MALDI In-Source Decay Mass Spectrometry. Journal of Physical Chemistry B, 117 (8), 2321-2327. doi:10.1021/jp311464k
Peer Reviewed verified by ORBi

Mazzucchelli, G., Smargiasso, N., Baiwir, D., Louis, E., De Pauw, E., & MEUWIS, M.-A. (2013). Comparison of five serum depletion or fractionation methods applied for clinical biomarkers discovery studies [Poster presentation]. 61st ASMS Conference on Mass Spectrometry and Allied Topics.

Asakawa, D., Smargiasso, N., Quinton, L., & De Pauw, E. (2013). Peptide backbone fragmentation initiated by side-chain loss at cysteine residue in matrixassisted laser desorption/ionization in-source decay mass spectrometry. Journal of Mass Spectrometry, 48, 352-360. doi:10.1002/jms.3182
Peer Reviewed verified by ORBi

Debois, D., Smargiasso, N., Demeure, K., Asakawa, D., Zimmerman, T., Quinton, L., & De Pauw, E. (2013). MALDI In-Source Decay, from sequencing to imaging. Topics in Current Chemistry, 331, 117-141. doi:10.1007/128_2012_363
Peer Reviewed verified by ORBi

Debois, D., Jourdan, E., Smargiasso, N., Ongena, M., Thonart, P., & De Pauw, E. (September 2012). Distribution and identification of molecular interactions between tomato roots and bacterial biofilms [Paper presentation]. 19th International Mass Spectrometry Conference, Kyoto, Japan.

Akasawa, D., Smargiasso, N., & De Pauw, E. (2012). Identification and Relative-quantification of Glycans by Matrix-assisted Laser Desorption/Ionization In-Source Decay with Hydrogen Abstraction. Analytical Chemistry. doi:10.1021/ac3014737
Peer Reviewed verified by ORBi

Jonlet, P., Smargiasso, N., Waxweiler, S., Collard, A., & De Pauw, E. (03 April 2012). Study of glycosylation of Antibodies produced in serum-free medium [Paper presentation]. XVIIème Rencontres du Club Jeune de la Société Française de Spectrométrie de Masse, La Bresse, France.

Smargiasso, N., Quinton, L., & De Pauw, E. (March 2012). 2-Aminobenzamide and 2-Aminobenzoic Acid as New MALDI Matrices Inducing Radical Mediated In-Source Decay of Peptides and Proteins. Journal of the American Society for Mass Spectrometry, 23, 469-474. doi:10.1007/s13361-011-0307-5
Peer Reviewed verified by ORBi

Quinton, L., Gilles, N., Smargiasso, N., Kiehne, A., & De Pauw, E. (November 2011). An Unusual Family of Glycosylated Peptides Isolated from Dendroaspis angusticeps Venom and Characterized by Combination of Collision Induced and Electron Transfer Dissociation. Journal of the American Society for Mass Spectrometry, 22 (11), 1891-1897. doi:10.1007/s13361-011-0210-0
Peer Reviewed verified by ORBi

Jonlet, P., Smargiasso, N., Waxweiler, S., Collard, A., & De Pauw, E. (20 September 2011). Étude de la glycosylation d’anticorps produits en milieu sans sérum [Poster presentation]. Spectrométrie de Masse et Analyse Protéomique, Avignon, France.

Far, J., Mazzucchelli, G., Meuwis, M.-A., Smargiasso, N., & De Pauw, E. (31 March 2011). Mass spectrometry applied to biomolecules analysis [Paper presentation]. Farm Animal Proteomics, Glascow, United Kingdom.

Smargiasso, N., & De Pauw, E. (June 2010). Influence of the matrix on the In Source Decay of permethylated glycans during MALDI-TOF analysis [Poster presentation]. 58th ASMS Conference on Mass Spectrometry And Allied Topics, Salt Lake City, UT, United States.

Lemaire, P., Debois, D., Quinton, L., Smargiasso, N., Gabelica, V., & De Pauw, E. (25 May 2010). Hydrogen/Deuterium Exchange combined to MALDI Mass Spectrometry : The Importance of the Choice of the Matrix [Poster presentation]. 58th ASMS Conference on Mass Spectrometry, Salt Lake City (UT), United States.

Rosu, F., Gabelica, V., Smargiasso, N., Mazzucchelli, G., Shin-ya, K., & De Pauw, E. (2010). Cation Involvement in Telomestatin Binding to G-Quadruplex DNA. Journal of Nucleic Acids, 121259. doi:10.4061/2010/121259
Peer Reviewed verified by ORBi

Smargiasso, N., & De Pauw, E. (2010). Optimization of Matrix Conditions for the Control of MALDI In-Source Decay of Permethylated Glycans. Analytical Chemistry, sous presee. doi:10.1021/ac1017452
Peer Reviewed verified by ORBi

Quinton, L., Demeure, K., Resemann, A., Deleuze, C., Balbeur, D., Smargiasso, N., Mazzucchelli, G., & Suckau, D. (June 2009). MALDI-Top-Down of Proteins: Overview and Applications [Paper presentation]. Bruker User's Meeting - 57th American society for Mass spectrometry Conference, Philadelphia, United States.

Smargiasso, N., Gabelica, V., Damblon, C., Rosu, F., De Pauw, E., Teulade-Fichou, M.-P., Rowe, J. A., & Claessens, A. (2009). Putative DNA G-quadruplex formation within the promoters of Plasmodium falciparum var genes. BMC Genomics, 10, 362. doi:10.1186/1471-2164-10-362
Peer Reviewed verified by ORBi

Monchaud, D., Allain, C., Bertrand, H., Smargiasso, N., Rosu, F., Gabelica, V., De Cian, A., Mergny, J.-L., & Teulade-Fichou, M.-P. (2008). Ligands playing musical chairs with G-quadruplex DNA: A rapid and simple displacement assay for identifying selective G-quadruplex binders. Biochimie, 90 (8), 1207-1223. doi:10.1016/j.biochi.2008.02.019
Peer Reviewed verified by ORBi

Mazzucchelli, G., Gabelica, V., Smargiasso, N., Fleron, M., Ashimwe, W., Rosu, F., De Pauw-Gillet, M.-C., Riou, J.-F., & De Pauw, E. (2008). Proteome alteration induced by hTERT transfection of human fibroblast cells. Proteome Science, 6 (1), 12. doi:10.1186/1477-5956-6-1
Peer Reviewed verified by ORBi

Smargiasso, N., Rosu, F., Baker, E., Bowers, M., Colson, P., De Pauw, E., & Gabelica, V. (2008). Novel G-Quadruplex Higher Order Assemblies Revealed by Electrospray Ionization Mass Spectrometry.

Mazzucchelli, G., Gabelica, V., Smargiasso, N., Rosu, F., De Pauw-Gillet, M.-C., Riou, J.-F., & De Pauw, E. (2008). Proteomic analysis of telomerase inhibition by telomere specific ligands. Anticancer Research, 28 (5c), 3257-3258.
Peer Reviewed verified by ORBi

Smargiasso, N., Rosu, F., Hsia, W., Colson, P., Baker, E. S., Bowers, M. T., De Pauw, E., & Gabelica, V. (2008). G-Quadruplex DNA Assemblies: Loop Length, Cation Identity, and Multimer Formation. Journal of the American Chemical Society, 130 (31), 10208-10216. doi:10.1021/ja801535e
Peer Reviewed verified by ORBi

Smargiasso, N., Mazzucchelli, G., Gabelica, V., De Pauw-Gillet, M.-C., Elmoualij, B., Zorzi, W., & De Pauw, E. (October 2006). Capture and identification of proteins bound to the telomeric single-strand sequence [Poster presentation]. Proteom'Lux, Luxembourg.

Mazzucchelli, G., Smargiasso, N., Rosu, F., Gabelica, V., Colson, P., Teulade- Fichou, M.-P., De Pauw-Gillet, M.-C., & De Pauw, E. (30 May 2006). G-quadruplex targeting drugs: from the gas phase structure of non covalent complexes to in vitro activity [Paper presentation]. 54th ASMS Conference, Seattle, United States.

Mazzucchelli, G., Smargiasso, N., Gerkens, P., Fléron, M., Guillonneau, F., De Pauw-Gillet, M.-C., & De Pauw, E. (28 August 2005). Detergent and sonication free nuclear protein fractionation of Wi 38 cells: an essential step prior to efficient 2D DIGE analysis [Poster presentation]. HUPO 4TH annual world congress, Munich, Germany.

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