Profil

Pequeux Christel

Département des sciences biomédicales et précliniques

GIGA Cancer - Tumours and development biology

See author's contact details
ORCID
0000-0001-8275-1489
Main Referenced Co-authors
Foidart, Jean-Michel  (49)
Noël, Agnès  (43)
Blacher, Silvia  (38)
Gallez, Anne  (28)
Cataldo, Didier  (23)
Main Referenced Keywords
Estetrol (19); estetrol (8); Breast Cancer (6); oxytocin (6); Hormone Replacement Therapy (5);
Main Referenced Unit & Research Centers
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (6)
Giga-Cancer - ULiège [BE] (5)
Centre Interfacultaire de Recherche du Médicament - CIRM (2)
centre d'immunologie, université de Liège (2)
GIGA‐R - Giga‐Research - ULiège [BE] (1)
Main Referenced Disciplines
Oncology (72)
Reproductive medicine (gynecology, andrology, obstetrics) (30)
Endocrinology, metabolism & nutrition (15)
Pharmacy, pharmacology & toxicology (11)
Neurology (7)

Publications (total 140)

The most downloaded
1427 downloads
Scantamburlo, G., Hansenne, M., Fuchs, S., Pitchot, W., Marechal, P., Pequeux, C., Ansseau, M., & Legros, J.-J. (May 2007). Plasma oxytocin levels and anxiety in patients with major depression. Psychoneuroendocrinology, 32 (4), 407-410. doi:10.1016/j.psyneuen.2007.01.009 https://hdl.handle.net/2268/6401

The most cited

253 citations (Scopus®)

Scantamburlo, G., Hansenne, M., Fuchs, S., Pitchot, W., Marechal, P., Pequeux, C., Ansseau, M., & Legros, J.-J. (May 2007). Plasma oxytocin levels and anxiety in patients with major depression. Psychoneuroendocrinology, 32 (4), 407-410. doi:10.1016/j.psyneuen.2007.01.009 https://hdl.handle.net/2268/6401

Pequeux, C. (May 2024). Estetrol combined to progesterone for menopause or contraception indication has limited effect on breast cancer growth: a preclinical study [Paper presentation]. 21th World Congress of Gynecological Endocrinology, Firenze, Italy.
Editorial reviewed

Wuidar, V., Dias Da Silva, I., Zielonka, M., Flas, C., & Pequeux, C. (06 February 2024). Does pulsed natural estrogen reduce breast cancer risk? [Poster presentation]. Séminaire Télévie 2024.

Fébrissy, C., Adlanmerini, M., Pequeux, C., Boudou, F., Buscato, M., Gargaros, A., Gilardi-Bresson, S., Boriak, K., Laurell, H., Fontaine, C., Katzenellenbogen, B. S., Katzenellenbogen, J. A., Guillermet-Guibert, J., Arnal, J.-F., Metivier, R., & Lenfant, F. (01 January 2024). Reprogramming of endothelial gene expression by tamoxifen inhibits angiogenesis and ERα-negative tumor growth. Theranostics, 14 (1), 249 - 264. doi:10.7150/thno.87306
Peer Reviewed verified by ORBi

Pequeux, C. (October 2023). Estetrol combined to progesterone for menopause or contraception indication has limited effect on breast cancer growth [Paper presentation]. 9th Annual MetNet International Meeting, Barcelona, Spain.
Editorial reviewed

Tskitishvili, E., Palazzo, C., Foidart, J.-M., Piel, G., & Pequeux, C. (15 June 2023). Use of liposome-encapsulated estetrol for treatment of neonatal hypoxic-ischemic encephalopathy. Brain Research, 1809, 148369. doi:10.1016/j.brainres.2023.148369
Peer Reviewed verified by ORBi

Gallez, A., Nys, G., Wuidar, V., Dias Da Silva, I., Taziaux, M., Kinet, V., Tskitishvili, E., Noël, A., Foidart, J.-M., Piel, G., Fillet, M., & Pequeux, C. (03 June 2023). Comparison of Estetrol Exposure between Women and Mice to Model Preclinical Experiments and Anticipate Human Treatment. International Journal of Molecular Sciences, 24 (11), 9718. doi:10.3390/ijms24119718
Peer Reviewed verified by ORBi

Wuidar, V., Dias Da Silva, I., & Pequeux, C. (02 February 2023). Does pulsed estrogen therapy reduce breast cancer risk? [Poster presentation]. SéminaireTélévie 2023, Louvain, Belgium.
Editorial reviewed

Dias Da Silva, I., Wuidar, V., Nisolle, M., & Pequeux, C. (02 February 2023). Differential effects of menopause hormone therapies on human endometrium and breast cancer [Poster presentation]. Séminaire Télévie 2023.
Editorial reviewed

Dias Da Silva, I., Wuidar, V., Nizet, C., Nisolle, M., & Pequeux, C. (10 November 2022). Deciphering specific estrogen signaling in cell populations of human breast and human endometrium [Poster presentation]. Nuclear Receptor Research Network Meeting, Utrecht, Netherlands.
Editorial reviewed

Wuidar, V., Dias Da Silva, I., & Pequeux, C. (10 November 2022). Does pulsed estrogen therapy recude breast cancer risk? [Poster presentation]. Nuclear Receptor Research Network Meeting, Utrecht, Netherlands.
Editorial reviewed

Pequeux, C. (13 October 2022). Estetrol et cancer du sein [Paper presentation]. 15ème Journées de Sénologie Interactive, Paris, France.
Editorial reviewed

Wuidar, V., Dias Da Silva, I., & Pequeux, C. (23 September 2022). Does pulsed estrogen therapy reduce breast cancer risk ? [Poster presentation]. International Meeting on Rapid Responses to Steroid Hormones, Paris, France.
Editorial reviewed

Dias Da Silva, I., Wuidar, V., Nizet, C., Nisolle, M., & Pequeux, C. (23 September 2022). Deciphering specific estrogen signaling in cell populations of human breast and human endometrium [Poster presentation]. International Meeting on Rapid Responses to Steroid Hormones.
Editorial reviewed

Pequeux, C. (2022). Estetrol and breast cancer. In Proceedings of RRSH 2022. not applicable.
Editorial reviewed

Dias Da Silva, I., Wuidar, V., Nizet, C., Nisolle, M., & Pequeux, C. (06 September 2022). Deciphering specific estrogen signaling in cell populations of human breast and human endometrium [Poster presentation]. GIGA-Day.
Editorial reviewed

Wuidar, V., Dias Da Silva, I., & Pequeux, C. (06 September 2022). Does pulsed estrogen therapy reduce breast cancer risk ? [Poster presentation]. GIGA-DAY, Liège, Belgium.
Editorial reviewed

Dias Da Silva, I., Wuidar, V., NISOLLE, M., NIZET, C., & Pequeux, C. (May 2022). Deciphering specific estrogen signaling in cell populations of human breast and human endometrium through innovative models [Paper presentation]. 10th French Nuclear Receptors Meeting, Toulouse, France.
Editorial reviewed

Dias Da Silva, I., Wuidar, V., Duysinx, J., Crevet, L., Fioramonti, M., NIZET, C., NISOLLE, M., Van Keymeulen, A., & Pequeux, C. (08 April 2022). Estrogen and analogs signaling in the prevention and treatment of breast cancer [Poster presentation]. Séminaire Télévie, Liege, Belgium.
Editorial reviewed

Wuidar, V., Dias Da Silva, I., Duysinx, J., NIZET, C., & Pequeux, C. (14 December 2021). Human breast organoids: a useful tool to assess breast safety of new menopausal hormone therapy formulations [Poster presentation]. Giga-Cancer Day, Liège, Belgium.
Editorial reviewed

Wuidar, V., Dias Da Silva, I., Duysinx, J., NIZET, C., & Pequeux, C. (12 November 2021). Human breast organoids: a promising model to assess breast safety of new menopausal hormone therapy formulations [Paper presentation]. 14th Congress of the European Society of Gynecology, Venise, Italy.
Editorial reviewed

Pequeux, C., Gallez, A., & Foidart, J.-M. (10 November 2021). Estetrol and mammary gland : friends or foes? [Paper presentation]. 14° congress of the european society of Gynecology, Venise, Italy.
Peer reviewed

Gallez, A., Dias Da Silva, I., Wuidar, V., Foidart, J.-M., & Pequeux, C. (September 2021). Estetrol and Mammary Gland: Friends or Foes? Journal of Mammary Gland Biology and Neoplasia, 26 (3), 297 - 308. doi:10.1007/s10911-021-09497-0
Peer Reviewed verified by ORBi

Dias Da Silva, I., Wuidar, V., Duysinx, J., NISOLLE, M., & Pequeux, C. (2021). Patient-derived xenograft (PDX) of endometrium: a promising model to assess endometrium safety of new menopausal hormone treatments [Poster presentation]. GIGA Cancer Day.
Editorial reviewed

Wuidar, V., Gillot, L., Dias Da Silva, I., Lebeau, A., Gallez, A., & Pequeux, C. (2021). Sex-based differences in the tumor microenvironment. In Tumor Microenvironment - Novel Concepts. Springer Nature. doi:10.1007/978-3-030-73119-9_23
Peer reviewed

Dias Da Silva, I., Wuidar, V., Duysinx, J., NISOLLE, M., & Pequeux, C. (2021). Patient-derived xenograft (PDX) of endometrium: a promising model to assess endometrium safey of new menopausal hormone treatments [Paper presentation]. 14th Congress of the European Society of Gynecology, Venise, Italy.
Editorial reviewed

Gallez, A., Blacher, S., Maquoi, E., Konradowski, E., Joiret, M., Primac, I., Gérard, C., Taziaux, M., Houtman, R., Geris, L., Lenfant, F., Marangoni, E., Sounni, N. E., Foidart, J.-M., Noël, A., & Pequeux, C. (2021). Estetrol combined to progestogen for menopause or contraception indication is neutral on breast cancer. Cancers. doi:10.3390/cancers13102486
Peer Reviewed verified by ORBi

Pequeux, C. (02 December 2020). Comparison of MHT treatments based on Estradiol or Estetrol on breast cancer: a preclinical study [Paper presentation]. 19th Congress of the International Society of Gynaecological Endocrinology, Florence, Italy.
Editorial reviewed

Gallez, A., BLACHER, S., Foidart, J.-M., & Pequeux, C. (06 March 2020). Comparison of MHT treatments based on Estradiol or Estetrol on breast cancer : a preclinical study [Paper presentation]. 19th world congress Gynecologycal Endocrinology, Florence, Italy.

Gallez, A., BLACHER, S., Primac, I., Foidart, J.-M., & Pequeux, C. (04 March 2020). Comparison of Estradiol and Estetrol on Estrogen Receptor alpha signaling [Paper presentation]. ISGE 2020.
Peer reviewed

Dias Da Silva, I., Gallez, A., & Pequeux, C. (03 March 2020). Characterization of estrogen and analog molecular effects in breast cancer prevention and treatment [Poster presentation]. EMBO Practical Course: Techniques for Mammary Gland Research, Heidelberg, Germany.

Blacher, S., Gallez, A., Gérard, C., Dias Da Silva, I., & Pequeux, C. (03 March 2020). Quantitative assessment of mouse mammary gland morphology using automated digital image processing and TEB detection [Poster presentation]. EMBO Practical Course: Techniques for Mammary Gland Research, Heidelberg, Germany.

Gallez, A.* , Palazzo, C.* , Blacher, S., Tskitishvili, E., Noël, A., Foidart, J.-M., Evrard, B., Pequeux, C.* , & Piel, G.*. (05 January 2020). Liposomes and drug-in-cyclodextrin-in-liposomes formulations encapsulating 17β-estradiol: an innovative drug delivery system that prevents the activation of the membrane-initiated steroid signaling (MISS) of estrogen receptor α. International Journal of Pharmaceutics, 573, 118861. doi:10.1016/j.ijpharm.2019.118861
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Pequeux, C., Gérard, C., Gallez, A., & Foidart, J.-M. (2020). Oestrogènes, progestérone, progestatifs et sein. In M. Espié, Le SEIN, du Normal au Pathologique: état de l'art (4ème édition, pp. 64-79). Paris, France: ESKA.
Peer reviewed

DELHEZ, A., LEFEBVRE, P., Pequeux, C., Malgrange, B., & Delacroix, L. (2020). Auditory function and dysfunction:estrogen makes a difference. Cellular and Molecular Life Sciences, 77, 619-635. doi:10.1007/s00018-019-03295-y
Peer Reviewed verified by ORBi

Rocks, N., Vanwinge, C., Radermecker, C., Blacher, S., Gilles, C., Marée, R., Gillard, A., Evrard, B., Pequeux, C., Marichal, T., Noël, A., & Cataldo, D. (08 September 2019). Ozone-primed neutrophils promote early steps of tumor cell metastasis to lungs by enhancing their NET production [Poster presentation]. IASLC 2019 World Conference on Lung Cancer.

Primac, I., Maquoi, E., Blacher, S., Heljasvaara, R., Van Deun, J., Smeland, H. Y. H., Canale, A., Louis, T., Stuhr, L., Sounni, N. E., Cataldo, D., Pihlajaniemi, T., Pequeux, C., De Wever, O., Gullberg, D., & Noël, A. (09 July 2019). Stromal integrin alpha11 regulates PDGFR-beta signaling and promotes breast cancer progression. Journal of Clinical Investigation, 130. doi:10.1172/JCI125890
Peer Reviewed verified by ORBi

Rocks, N., Vanwinge, C., Radermecker, C., Blacher, S., Gilles, C., Marée, R., Gillard, A., Evrard, B., Pequeux, C., Marichal, T., Noël, A., & Cataldo, D. (29 May 2019). Ozone-primed neutrophils promote early steps of tumor cell metastasis to lungs by enhancing their NET production. Thorax, 0, 1-12. doi:10.1136/thoraxjnl-2018-211990
Peer Reviewed verified by ORBi

Gallez, A., Gérard, C., BLACHER, S., Primac, I., Lenfant, F., Foidart, J.-M., & Pequeux, C. (May 2019). Impact of Estetrol versus Estradiol on mammary gland and breast cancer: an opportunity for menopause treatment [Poster presentation]. Eleventh Annual ENBDC workshop : Methods in mammary gland biology and breast cancer, Weggis, Switzerland.

Pequeux, C. (22 March 2019). Estetrol and breast safety [Paper presentation]. Conferences of the University of Pisa, Pise, Italy.

Foidart, J.-M., GASPARD, U., Pequeux, C., Jost, M., Gordenne, V., Tskitishvili, E., Gallez, A., Valera, M.-C., Gourdy, P., Fontaine, C., Henrion, D., Genazzani, A. R., Lenfant, F., & Arnal, J.-F. (2019). Unique Vascular Benefits of Estetrol, a Native Fetal Estrogen with Specific Actions in Tissues (NEST). In R. Diaz Brinton, A. Genazzani, T. Simoncini, ... J. Stevenson, Sex Steroids' Effects on Brain, Heart and Vessels: Volume 6: Frontiers in Gynecological Endocrinology. Cham, Switzerland: Springer Nature. doi:10.1007/978-3-030-11355-1
Peer reviewed

Dubois, C., Rocks, N., Blacher, S., Primac, I., Gallez, A., Garcia-Caballero, M., Gérard, C., Brouchet, L., Noël, A., Lenfant, F., Cataldo, D., & Pequeux, C. (2019). Lymph/angiogenesis contributes to sex differences in lung cancer through oestrogen receptor alpha signalling. Endocrine-Related Cancer, 26 (2), 201-216. doi:10.1530/ERC-18-0328
Peer Reviewed verified by ORBi

Palazzo, C., Laloy, J., Delvigne, A. S., Nys, G., Fillet, M., Dogne, J. M., Pequeux, C., Foidart, J.-M., Evrard, B., & Piel, G. (2019). Development of injectable liposomes and drug-in-cyclodextrin-in-liposome formulations encapsulating estetrol to prevent cerebral ischemia of premature babies. European Journal of Pharmaceutical Sciences, 9 (127), 52-59. doi:10.1016/j.ejps.2018.10.006
Peer Reviewed verified by ORBi

Pequeux, C. (19 December 2018). Estrogen and nanovectors [Paper presentation]. 1st CIRM day, Liège, Belgium.

Tskitishvili, E., Pequeux, C., VIELLEVOYE, R., Nisolle, M., Noël, A., & Foidart, J.-M. (13 November 2018). Estetrol, a newly designated orphan drug, for attenuation of neonatal Hypoxic-Ischemic Encephalopathy (HIE) [Poster presentation]. "From Rare to Care: Discovery, Modeling and Translation of Rare Diseases", Vienna, Austria.

Pequeux, C. (24 May 2018). Inclusion of 17beta-estradiol into liposome: a tool to study the molecular mechanisms of estrogen receptors [Paper presentation]. 8th Nuclear Receptor Meeting, Lyon, France.
Editorial reviewed

Gallez, A., Palazzo, C., Primac, I., Evrard, B., Noël, A., Piel, G., & Pequeux, C. (24 May 2018). Inclusion of 17β-estradiol into liposome : a tool to study the molecular mechanisms of estrogen receptors [Paper presentation]. 8th Meeting on Nuclear Receptors, Lyon, France.

Gallez, A., Palazzo, C., Evrard, B., Noël, A., Piel, G., & Pequeux, C. (2018). Inclusion of 17β-estradiol into liposome prevent the activation of membrane initiated signaling of ERalpha [Poster presentation]. EMBO Workshop/ Nuclear receptors and biological networks, Kolymbari, Greece.

Gallez, A., Palazzo, C., Evrard, B., Noël, A., Piel, G., & Pequeux, C. (2018). Liposomal and drug-in cyclodextrin-in-liposome formulations encapsulating 17β-estradiol prevent the activation of the non-genomic effects of estrogen receptor alpha [Paper presentation]. The 18th world congress of Gynecological Endocrinology, Florence, Italy.

Gallez, A., BLACHER, S., Gérard, C., Noël, A., Arnal, J.-F., Foidart, J.-M., & Pequeux, C. (07 November 2017). ERα- and dose-dependent effect of estetrol on angiogenesis and tumor growth [Poster presentation]. 10th Nuclear Receptor Research Network Meeting, leuven, Belgium.

Tskitishvili, E., Pequeux, C., Munaut, C., VIELLEVOYE, R., NISOLLE, M., Noël, A., & Foidart, J.-M. (20 October 2017). ESTROGEN RECEPTORS AND ESTETROL-DEPENDENT NEUROPROTECTIVE ACTIONS: A PILOT STUDY [Paper presentation]. The 12th International Congress of the European Society of Gynecology, Barcelona, Spain.

Nys, G., Gallez, A., Kok, M., COBRAIVILLE, G., Servais, A.-C., Piel, G., Pequeux, C.* , & Fillet, M.*. (05 June 2017). Whole blood microsampling for the quantitation of estetrol without derivatization by liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 140, 258-265. doi:10.1016/j.jpba.2017.02.060
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Gallez, A., BLACHER, S., Lenfant, F., Arnal, J.-F., Noël, A., Foidart, J.-M., & Pequeux, C. (19 May 2017). Dose-Dependant effect of Estetrol on Angiogenesis and Tumor growth [Paper presentation]. 7th Meeting on Nuclear Receptor (JRN), Montpellier, France.

Dubois, C., BLACHER, S., Primac, I., García Caballero, M., Gallez, A., Rocks, N., Pequeux, C., & Cataldo, D. (10 May 2017). Le microenvironement tumoral, un acteur essentiel de la différence liée au genre dans le développement des cancers pulmonaires [Paper presentation]. GSK award 2017, Bruxelles, Belgium.

Primac, I., Blacher, S., cimino, J., Carnet, O., Liaudet-Coopman, E., de Wever, O., Sounni, N. E., Pequeux, C., Gullberg, D., & Noël, A. (24 April 2017). Cancer associated fibroblast-derived integrin α11 regulates PDGFRβ signaling to promote breast cancer progression [Paper presentation]. 7eme Congrès de la Société Française d’Angiogenèse, Toulouse, France.

Gallez, A., Blacher, S., Lenfant, F., Arnal, J.-F., Polette, M., Birembaut, P., Noël, A., Foidart, J.-M., & Pequeux, C. (24 April 2017). Dose-dependent effect of Estetrol on Angiogenesis and Tumor Growth [Poster presentation]. 7ième congrès de la Société Française d'Angiogenèse, Toulouse, France.

Nys, G., Servais, A.-C., Pequeux, C., & Fillet, M. (29 March 2017). Lc-chip versus UHPLC-tandem mass spectrometry for the quantitation of estetrol and estradiol without derivatization after whole blood microsampling [Paper presentation]. 12éme congrès francophone sur les sciences séparatives et les couplages, Paris, France.

Gérard, C., Gallez, A., Dubois, C., Drion, P., Delahaut, P., Quertemont, E., Noël, A., & Pequeux, C. (March 2017). Accurate Control of 17beta-Estradiol Long-Term Release Increases Reliability and Reproducibility of Preclinical Animal Studies. Journal of Mammary Gland Biology and Neoplasia, 22 (1), 1-11. doi:10.1007/s10911-016-9368-1
Peer Reviewed verified by ORBi

Nys, G., Servais, A.-C., Pequeux, C., & Fillet, M. (March 2017). Microsampling and micropreparation of biological fluids for sensitive quantitation of estetrol by LC-(Chip)-MS/MS [Paper presentation]. 33th International Symposium on Microscale Bioseparations (MSB), Madrid, Spain.

Fillet, M., Nys, G., Servais, A.-C., & Pequeux, C. (March 2017). MICROSAMPLING AND MICROPREPARATION OF BIOLOGICAL FLUIDS FOR SENSITIVE QUANTITATION OF ESTETROL BY LC-(CHIP)-MS/MS [Paper presentation]. Microscale separation and bioanalysis (MSB).

Tskitishvili, E., Pequeux, C., Munaut, C., VIELLEVOYE, R., Nisolle, M., Noël, A., & Foidart, J.-M. (2017). Estrogen receptors and estetroldependent neuroprotective actions: a pilot study. Journal of Endocrinology, 232 (1), 85-95. doi:10.1530/JOE-16-0434
Peer Reviewed verified by ORBi

Dubois, C., Blacher, S., García Caballero, M., Rocks, N., Pequeux, C., & Cataldo, D. (08 December 2016). Gender differences in lung tumor development: implication of estrogens [Poster presentation]. Séminaire Télévie, Bruxelles, Belgium.

Dubois, C., Rocks, N., Blacher, S., Pequeux, C., Cataldo, D., & García Caballero, M. (08 December 2016). Estradiol increases lung tumor development in female mice through stromal estrogen receptor [Paper presentation]. Séminaire Télévie 2016, Bruxelles, Belgium.

Nys, G., Servais, A.-C., Pequeux, C., & Fillet, M. (17 October 2016). Pharmacokinetic study of estetrol in murin model developing a whole blood microsampling, extraction procedure and an UHPLC-MS/MS method [Paper presentation]. Forum of pharmaceutical sciences, Brussels, Belgium.

Dubois, C., Blacher, S., García Caballero, M., Rocks, N., Cataldo, D., & Pequeux, C. (14 October 2016). Gender differences in lung tumor progression : implication of estrogens [Poster presentation]. Journées de recherche respiratoire, Nice, France.

Dubois, C., Blacher, S., García Caballero, M., Rocks, N., Pequeux, C., & Cataldo, D. (09 September 2016). Gender differences in lung tumor development: implication of estrogens [Poster presentation]. Annual Mini symposium 2016, Bruxelles, Belgium.

Dubois, C., Blacher, S., García Caballero, M., Pequeux, C., & Cataldo, D. (09 September 2016). Gender differences in lung tumor development: implication of estrogens [Paper presentation]. Annual Mini symposium 2016, Bruxelles, Belgium.

Gallez, A., Gérard, C., Blacher, S., Noël, A., Foidart, J.-M., & Pequeux, C. (30 May 2016). Estetrol, a natural SERM exhibiting combined estrogenic and anti-estrogenic properties on mammary gland and breast cancer [Poster presentation]. Biomedica Life Sciences Summit 2016 - 30/31 May 2016, Aachen, Germany.

Dubois, C., Rocks, N., CATALDO, D., & Pequeux, C. (27 May 2016). Gender differences in lung tumor development : implication of estrogens [Paper presentation]. GIGA cancer séminaire 2016.

Tskitishvili, E., Pequeux, C., Munaut, C., VIELLEVOYE, R., Nisolle, M., Noël, A., & Foidart, J.-M. (2016). Use of Estetrol with other Steroids for Attenuation of Neonatal Hypoxic-Ischemic brain injury:to combine or not to combine? Oncotarget. doi:10.18632/oncotarget.9591
Peer Reviewed verified by ORBi

Dubois, C., Rocks, N., Cataldo, D., & Pequeux, C. (11 May 2016). Gender differences in lung tumor development : implication of estrogens [Paper presentation]. GSK award 2016, Bruxelles, Belgium.

Pequeux, C. (09 May 2016). Estetrol, a natural SERM exhibiting combined estrogenic and anti-estrogenic properties on mammary gland and breast cancer [Paper presentation]. 6th Nuclear Receptor Meeting, Paris, France.

Gérard, C., Gallez, A., Blacher, S., Noël, A., Silva, E., Gompel, A., Lenfant, F., Arnal, J.-F., Foidart, J.-M., & Pequeux, C. (09 May 2016). Estetrol, a natural SERM exhibiting combined estrogenic and antiestrogenic properties on mammary gland and breast cancer [Paper presentation]. 6th Nuclaer Receptor Meeting, Paris, France.

Tskitishvili, E., VIELLEVOYE, R., Gérard, C., Pequeux, C., Munaut, C., Nisolle, M., Noël, A., & Foidart, J.-M. (May 2016). Neonatal Hypoxic-Ischemic Encephalopathy: a new view of an old problem. Références en Gynécologie Obstétrique, 17 (1-1).
Peer reviewed

Dubois, C., Rocks, N., CATALDO, D., & Pequeux, C. (25 January 2016). In vivo and in vitro approaches to study how estradiol can impact lung cancer development [Poster presentation]. GIGA Day 2016.

Blacher, S., Gérard, C., Gallez, A., Foidart, J.-M., Noël, A., & Pequeux, C. (2016). Quantitative assessment of mouse mammary gland morphology using automated digital image processing and TEB detection. Endocrinology, 20151601. doi:10.1210/en.2015-1601
Peer Reviewed verified by ORBi

Gallez, A., Gérard, C., Blacher, S., Noël, A., Foidart, J.-M., & Pequeux, C. (2016). Impact of estetrol on breast cancer development, metastatic dissemination and angiogenesis [Poster presentation]. Giga Cancer Day, Liège, Belgium.

Dubois, C., Rocks, N., CATALDO, D., & Pequeux, C. (03 December 2015). Study of the impact of estradiol on lung tumor development, carcinogenesis and on the angiogenesis through three in vivo models and through the Lewis Lung Carcinoma (LLC) cells responses in vitro [Poster presentation]. Séminaire Télévie 2015.

Gérard, C., Gallez, A., Silva, E., Gompel, A., Lenfant, F., Arnal, J.-F., Foidart, J.-M., & Pequeux, C. (14 November 2015). Estetrol : a new natural estrogen providing a safe therapeutic window for the treatment of menopause [Poster presentation]. Congrès de la Société Belge de la Ménopause (BMS), Bruxelles, Belgium.

Palazzo, C., Karim, R., Furst, T., Pequeux, C., Tskitishvili, E., Mawet, M., Maillard, C., Foidart, J.-M., Evrard, B., & Piel, G. (25 October 2015). LIPOSOME ENCAPSULATING ESTETROL FOR THE TREATMENT OF ISCHEMIA DISEASES IN PREMATURE BABIES [Poster presentation]. 2015 AAPS Annual Meeting and Exposition, Orlando, FLA, United States.

Pequeux, C. (24 October 2015). Estetrol: a natural SERM that may provide a safe therapeutic window for the treatment of menopausal symptoms [Paper presentation]. 11th Congress of the European Society of Gynecology, Prague, Czechia.

Dubois, C., Primac, I., Rocks, N., CATALDO, D., & Pequeux, C. (11 September 2015). Role of estrogens in carcinogenesis and cancer progression of bronchial carcinoma [Poster presentation]. EDT Annual Mini symposium 2015.

Palazzo, C., Karim, R., Pequeux, C., Tskitishvili, E., Mawet, M., Maillard, C., Foidart, J.-M., Evrard, B., & Piel, G. (02 June 2015). Liposome Encapsulating Estetrol For The Treatment Of Ischemia Diseases In Prematures Babies [Poster presentation]. Biomedica 2015, Genk, Belgium.

Gérard, C., Mestdagt, M., Tskitishvili, E., Communal, L., Gompel, A., Silva, E., Arnal, J.-F., Lenfant, F., Noël, A., Foidart, J.-M., & Pequeux, C. (2015). Combined estrogenic and anti-estrogenic properties of estetrol on breast cancer may provide a safe therapeutic window for the treatment of menopausal symptoms. Oncotarget. doi:10.18632/oncotarget.4184
Peer Reviewed verified by ORBi

Dubois, C., Primac, I., Rocks, N., CATALDO, D., & Pequeux, C. (13 May 2015). Role of estrogens in carcinogenesis and cancer progression of bronchial carcinoma  [Poster presentation]. GIGA cancer Day séminaire 2015.

Dubois, C., Primac, I., Rocks, N., CATALDO, D., & Pequeux, C. (06 May 2015). Rôles des œstrogènes sur le développement du carcinome bronchique [Paper presentation]. GSK award 2015.

Dubois, C., Primac, I., Rocks, N., CATALDO, D., & Pequeux, C. (27 January 2015). Role of estrogens in carcinogenesis and cancer progression of bronchial carcinoma  [Poster presentation]. GIGA Day 2015.

Gérard, C., Blacher, S., Communal, L., Courtin, A., Tskitishvili, E., Mestdagt, M., Munaut, C., Noël, A., Gompel, A., Pequeux, C.* , & Foidart, J.-M.*. (2015). Estetrol is a weak estrogen antagonizing estradiol-dependent mammary gland proliferation. Journal of Endocrinology, 224 (1), 86-95. doi:10.1530/JOE-14-0549
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* These authors have contributed equally to this work.

Carnet, O.* , Lecomte, J.* , Masset, A., Primac, I., Durré, T., Maertens, L., Detry, B., Blacher, S., Gilles, C., Péqueux, C., Paupert, J., Foidart, J.-M., Jerusalem, G., Cataldo, D., & Noël, A. (2015). Mesenchymal stem cells shed amphiregulin at the surface of lung carcinoma cells in a juxtacrine manner. Neoplasia, 17 (7), 552-63. doi:10.1016/j.neo.2015.07.002
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* These authors have contributed equally to this work.

Pequeux, C., & Tskitishvili, E. (27 November 2014). Estrogens and neonatal neuroprotection [Paper presentation]. SAB-GIGA-Cancer.

Tskitishvili, E., Nisolle, M., Munaut, C., Pequeux, C., Gérard, C., Noël, A., & Foidart, J.-M. (November 2014). Estetrol attenuates neonatal hypoxic–ischemic brain injury. Experimental Neurology, 261, 298-307. doi:10.1016/j.expneurol.2014.07.015
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Dubois, C., Primac, I., Rocks, N., CATALDO, D., & Pequeux, C. (30 September 2014). Role of estrogens in carcinogenesis and cancer progression of bronchial carcinoma [Poster presentation]. EDT Annual Mini symposium 2014.

Dubois, C., Primac, I., Rocks, N., CATALDO, D., & Pequeux, C. (11 June 2014). Rôles des œstrogènes sur le développement du carcinome bronchique [Paper presentation]. GSK award 2014.

Dubois, C., Primac, I., Rocks, N., CATALDO, D., & Pequeux, C. (19 May 2014). Role of estrogens in carcinogenesis and cancer progression of bronchial carcinoma  [Poster presentation]. GIGA-Day 2014.

Pequeux, C. (2014). Estradiol promotes the growth of Estrogen Receptor (ER)-negative tumors through host ERα driven angiogenesis [Paper presentation]. 16th World Congress of Gynecological Endocrinology, Firenze, Italy.

Abot, A., Fontaine, C., Buscato, M., Solinhac, R., Flouriot, G., Fabre, A., Drougard, A., Rajan, S., Laine, M., Milon, A., Muller, I., Henrion, D., Adlanmerini, M., Valera, M.-C., Gompel, A., Gérard, C., Pequeux, C., Mestdagt, M., Raymond-Letron, I., ... Arnal, J.-F. (2014). The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor alpha modulation, uncoupling nuclear and membrane activation. EMBO Molecular Medicine, 6 (10), 1328-46. doi:10.15252/emmm.201404112
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Maertens, L., Erpicum, C., Detry, B., Blacher, S., Lenoir, B., Carnet, O., Pequeux, C., Cataldo, D., Lecomte, J., Paupert, J., & Noël, A. (2014). Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis. PLoS ONE, 9 (9), 106976. doi:10.1371/journal.pone.0106976
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Pequeux, C. (2013). Estradiol promotes the growth of Estrogen Receptor (ER)-negative tumors through host ERα driven angiogenesis [Paper presentation]. IUAP Progress meeting.

Pequeux, C. (2013). Estrogens and tumor microenvironment [Paper presentation]. First CAFFEIN summer school.

Munaut, C., LORQUET, S., Pequeux, C., Coulon, C., Le Goarant, J., CHANTRAINE, F., Noël, A., GOFFIN, F., Tsatsaris, V., Subtil, D., & Foidart, J.-M. (March 2012). Differential expression of Vegfr-2 and its soluble form in preeclampsia. PLoS ONE, 7 (3), 33475. doi:10.1371/journal.pone.0033475
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Maquoi, E., Assent, D., Detilleux, J., Pequeux, C., Foidart, J.-M., & Noël, A. (26 January 2012). MT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis. Oncogene, 31 (4), 480-93. doi:10.1038/onc.2011.249
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Pequeux, C., Raymond-Letron, I., Blacher, S., Boudou, F., Adlanmerini, M., Fouque, M., Rochaix, P., Noël, A., Foidart, J.-M., Krust, A., Chambon, P., Brouchet, L., Arnal, J., & Lenfant, F. (2012). Stromal Estrogen Receptor-α Promotes Tumor Growth by Normalizing an Increased Angiogenesis. Cancer Research, 72 (12), 3010-3019. doi:10.1158/0008-5472.CAN-11-3768
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Berndt, S., Detilleux, J., Blacher, S., PERRIER d'HAUTERIVE, S., Pequeux, C., Munaut, C., Huhtaniemi, I., Fournier, T., Evain-Drion, D., Noël, A., & Foidart, J.-M. (2011). TGFbeta-receptor-dependent angiostimulation through the hyperglycosylated isoform of human chorionic gonadotropin. Placenta, 32 (9), 44.
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Gengoux, E., LORQUET, S., Hendrick, E., Berndt, S., Noël, A., Foidart, J.-M., Munaut, C., & Pequeux, C. (2011). Basal and induced release of soluble VEGFR-2 by endothelial and lymphatic cells [Poster presentation]. Giga Day, Liège, Belgium.

Pequeux, C. (2011). Estradiol promotes the growth of estrogen receptor (ER)-negative tumors throughout host ERalpha driven angiogenesis [Paper presentation]. 3ème congrès de la société française d'angiogenèse, Bordeaux, France.

Berndt, S., Blacher, S., PERRIER d'HAUTERIVE, S., Thiry, M., Tsampalas, M., Cruz, A., Pequeux, C., LORQUET, S., Munaut, C., Noël, A., & Foidart, J.-M. (06 March 2010). hCG: a pregnancy-related hormone stimulating angiogenesis and pericyte recruitment [Poster presentation]. 14th World Congress of Gynecological Endocrinology (ISGE), Firenze, Italy.

Foidart, J.-M., Munaut, C., Pequeux, C., Akolekar, R., & Nicolaides, K. (04 March 2010). Pathogenesis of Preeclampsia – from Immunology to Angiogenesis Inhibition [Paper presentation]. 14th World Congress of Gynecological Endocrinology (ISGE), Florence, Italy.

LORQUET, S., Berndt, S., Blacher, S., Gengoux, E., Peulen, O., Maquoi, E., Noël, A., Foidart, J.-M., Munaut, C., & Pequeux, C. (2010). Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment. FASEB Journal, 24 (10), 3782-95. doi:10.1096/fj.09-149070
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Berndt, S., Blacher, S., PERRIER d'HAUTERIVE, S., Thiry, M., Tsampalas, M., Cruz, A., Pequeux, C., LORQUET, S., Munaut, C., Noël, A., & Foidart, J.-M. (2010). hCG: a pregnancy-related homone stimulating angiogenesis and pericyte recruitment [Poster presentation]. 16th Intenational Vascular Biology Meeting, Los Angeles, United States.

Pequeux, C., LORQUET, S., Berndt, S., Blacher, S., Gengoux, E., Noël, A., Munaut, C., & Foidart, J.-M. (2010). Soluble forms of VEGF receptor-1 and -2 can promote mural cell migration” 16th Intenational Vascular Biology Meeting [Poster presentation]. 16th Intenational Vascular Biology Meeting, Los Angeles, United States.

Pequeux, C. (2010). Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment [Paper presentation]. Symposium on angiogenesis, Toulouse, France.

Lorquet, S., Pequeux, C., Munaut, C., & Foidart, J.-M. (2010). Aetiology and physiopathology of preeclampsia and related forms. Acta Clinica Belgica, 65 (4), 237-41. doi:10.1179/acb.2010.051
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Berndt, S., Blacher, S., PERRIER d'HAUTERIVE, S., Thiry, M., Tsampalas, M., Cruz, A., Pequeux, C., LORQUET, S., Munaut, C., Noël, A.* , & Foidart, J.-M.*. (2009). Chorionic Gonadotropin Stimulation of Angiogenesis and Pericyte Recruitment. Journal of Clinical Endocrinology and Metabolism, 94 (11), 4567-74. doi:10.1210/jc.2009-0443
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* These authors have contributed equally to this work.

Foidart, J.-M., Noël, A., Chantraine, F., Lorquet, S., Petit, P., Munaut, C., Berndt, S., Pequeux, C., & Schaaps, J.-P. (2009). Les défauts d'implantation placentaire et leurs conséquences sur la fonction endothéliale maternelle. Bulletin Académique National de Médecine, 193 (5), 1059-66.
Peer reviewed

Lorquet, S., Berndt, S., Blacher, S., Noël, A., Munaut, C., Foidart, J.-M., & Pequeux, C. (2008). Implication of VEGF receptor soluble forms, sVEGFR-1 and sVEGFR-2, in angiogenesis. Acta Clinica Belgica, 63/1, 48-58.
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Lorquet, S., Berndt, S., Blacher, S., Noël, A., Munaut, C., Foidart, J.-M., & Pequeux, C. (2008). Implication of soluble receptors of VEGF, sVEGFR-1 and sVEGFR-2, in angiogenesis. American Journal of Reproductive Immunology, 60/1, 85.
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Munaut, C., Lorquet, S., Pequeux, C., Blacher, S., Berndt, S., Frankenne, F., & Foidart, J.-M. (2008). Hypoxia is responsible for soluble vascular endothelial growth factor receptor-1 (VEGFR-1) but not for soluble endoglin induction in villous trophoblast. Human Reproduction, 23 (6), 1407-15. doi:10.1093/humrep/den114
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Scantamburlo, G., Hansenne, M., Fuchs, S., Pitchot, W., Marechal, P., Pequeux, C., Ansseau, M., & Legros, J.-J. (May 2007). Plasma oxytocin levels and anxiety in patients with major depression. Psychoneuroendocrinology, 32 (4), 407-410. doi:10.1016/j.psyneuen.2007.01.009
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Berndt, S., PERRIER d'HAUTERIVE, S., Blacher, S., Pequeux, C., Lorquet, S., Munaut, C., Applanat, M., Herve, M. A., Lamande, N., Corvol, P., van den Brule, F., Frankenne, F., Poutanen, M., Huhtaniemi, I., Geenen, V., Noël, A., & Foidart, J.-M. (December 2006). Angiogenic activity of human chorionic gonadotropin through LH receptor activation on endothelial and epithelial cells of the endometrium. FASEB Journal, 20 (14), 2630-2632. doi:10.1096/fj.06-5885fje
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Keegan, B. P., Akerman, B. L., Pequeux, C., & North, W. G. (February 2006). Provasopressin expression by breast cancer cells: implications for growth and novel treatment strategies. Breast Cancer Research and Treatment, 95 (3), 265-277. doi:10.1007/s10549-005-9024-8
Peer Reviewed verified by ORBi

Pequeux, C. (2006). Implication of VEGF receptor soluble forms, sVEGFR1 and sVEGFR2, in pathological angiogenesis [Paper presentation]. Symposium on angiogenesis: fundamental and clinical perspectives, Maastricht, Netherlands.

Pequeux, C., Breton, C., Hagelstein, M. T., Geenen, V., & Legros, J.-J. (November 2005). Oxytocin receptor pattern of expression in primary lung cancer and in normal human lung. Lung Cancer, 50 (2), 177-188. doi:10.1016/j.lungcan.2005.05.027
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Pequeux, C. (2005). Oxytocin and vasopressin implications in growth of human small-cell lung cancer [Paper presentation]. 15th meeting of the belgian endocrine society, Bruxelles, Belgium.

Hansenne, I., Rasier, G., Pequeux, C., Brilot, F., Renard, C., Breton, C., Greimers, R., Legros, J.-J., Geenen, V., & Martens, H. J. (January 2005). Ontogenesis and functional aspects of oxytocin and vasopressin gene expression in the thymus network. Journal of Neuroimmunology, 158 (1-2), 67-75. doi:10.1016/j.jneuroim.2004.08.007
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Pequeux, C., Keegan, B. P., Hagelstein, M. T., Geenen, V., Legros, J.-J., & North, W. G. (December 2004). Oxytocin- and vasopressin-induced growth of human small-cell lung cancer is mediated by the mitogen-activated protein kinase pathway. Endocrine-Related Cancer, 11 (4), 871-885. doi:10.1677/erc.1.00803
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Pequeux, C., Keegan, B. P., Hagelstein, M.-T., Geenen, V., North, W. G., & Legros, J.-J. (2003). Oxytocin and vasopressin autocrine/paracrine signaling in small cell lung carcinoma. International Journal of Molecular Medicine, 12/S1, 72.
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Pequeux, C. (2003). Oxytocin and vasopressin autocrine/paracrine signalling in small cell lung carcinoma [Paper presentation]. 8th world congress on advances in oncology and 6th international symposium on molecular medicine, Crete, Greece.

Pequeux, C. (2002). Expression membranaire et signalisation autocrine par l’ocytocine et la vasopressine dans les cancers pulmonaires à petites cellules [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/202896

Pequeux, C., Breton, C., Hendrick, J.-C., Hagelstein, M.-T., Martens, H., Winkler, R., Geenen, V., & Legros, J.-J. (15 August 2002). Oxytocin synthesis and oxytocin receptor expression by cell lines of human small cell carcinoma of the lung stimulate tumor growth through autocrine/paracrine signaling. Cancer Research, 62 (16), 4623-4629.
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Pequeux, C. (2002). Membrane conformation and transduction pathway of oxytocin and vasopressin in small cell lung cancer [Paper presentation]. Fifteenth annual neuroscience day at Dartmouth, Hanover, NH, United States.

Crasson, M., Beckers, V., Pequeux, C., Claustrat, B., & Legros, J.-J. (October 2001). Daytime 50 Hz Magnetic Field Exposure and Plasma Melatonin and Urinary 6-Sulfatoxymelatonin Concentration Profiles in Humans. Journal of Pineal Research, 31 (3), 234-41. doi:10.1034/j.1600-079X.2001.310307.x
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Pequeux, C., Hendrick, J.-C., Hagelstein, M.-T., Geenen, V., & Legros, J.-J. (2001). Novel plasma extraction procedure and development of a specific enzyme immunoassay of oxytocin: application to biological and clinical investigations of small-cell carcinoma of the lung. Scandinavian Journal of Clinical and Laboratory Investigation, 61 (5), 407-415. doi:10.1080/003655101316911468
Peer Reviewed verified by ORBi

Legros, J.-J., & Pequeux, C. (2001). Exploration de l'axe vasopressinergique dans les hyponatrémies. In N. Gueritée & J. Leclère (Eds.), Mises au point clinique d'endocrinologie, nutrition et métabolisme 2001.

Pequeux, C., Hagelstein, M.-T., Hendrick, J.-C., Geenen, V., North, W., & Legros, J.-J. (2001). Expression membranaire et signalisation autocrine par l'ocytocine et la vasopressine dans les cancers pulmonaires à petites cellules. Annales d'Endocrinologie.
Peer Reviewed verified by ORBi

Pequeux, C., Breton, C., Hagelstein, M.-T., Hendrick, J.-C., & Legros, J.-J. (2000). Oxytocin receptor of small cell carcinoma of human lung cell lines. Pflügers Archiv: European Journal of Physiology, 440/6.
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Boudare, M, Pequeux, C., Hagelstein, M.-T., Hendrick, JC, & Legros, J.-J. (1999). La vasopressine, mais pas l'ocytocinen ni le CRF, est impliquée dans la réponse du cortisol aux stress pschologiques, chez des humains sains mais anxieux. Annales d'Endocrinologie, 60 (4), 360.
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Pequeux, C., Brilot, F., Martens, H., Geenen, V., & Legros, J.-J. (1999). De nouveaux acteurs dans la physiopathologie du metabolisme de l'eau: les aquaporines. Revue Médicale de Liège, 54 (11), 867-74.
Peer reviewed

Boudarene, M., Pequeux, C., Hagelstein, M.-T., Timsit-Berthier, M., Petraglia, F., & Legros, J.-J. (1999). La vasopressine, mais pas l'ocytocine ni le CRF, est impliquée dans la réponse du cortisol au stress psychologique chez des humains sains mais anxieux. Annales d'Endocrinologie, 60/4.
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Pequeux, C. (1998). Vasopressine et ocytocine [Specialised master, UM - Université de Montpellier]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/202898

Pirard, F., Pequeux, C., Hendrick, J. C., & Legros, J.-J. (1997). Neurophysines et cancer pulmonaire a petites cellules. Revue Médicale de Liège, 52 (1), 22-6.
Peer reviewed

Pequeux, C. (1995). Agents de contraste hydrophobes pour l'imagerie de Résonance Magnétique, synthèse et propriétés de relaxation [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/202897

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