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Aerts Joël

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Main Referenced Co-authors
Luxen, André  (95)
Lemaire, Christian  (73)
Plenevaux, Alain  (64)
Salmon, Eric  (28)
Degueldre, Christian  (23)
Main Referenced Keywords
PET (18); SV2A (10); fluorine-18 (6); epilepsy (4); positron emission tomography (4);
Main Referenced Unit & Research Centers
GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège [BE] (66)
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (5)
CERMEP Lyon (2)
Giga-CRC In vivo Imaging (1)
INSERM/CFB (1)
Main Referenced Disciplines
Radiology, nuclear medicine & imaging (35)
Chemistry (33)
Neurosciences & behavior (20)
Life sciences: Multidisciplinary, general & others (10)
Pharmacy, pharmacology & toxicology (7)

Publications (total 113)

The most downloaded
2462 downloads
Maquet, P., Laureys, S., Peigneux, P., Fuchs, S., Petiau, C., Phillips, C., Aerts, J., Del Fiore, G., Degueldre, C., Meulemans, T., Luxen, A., Franck, G., Van der Linden, M., Smith, C., & Cleeremans, A. (August 2000). Experience-dependent changes in cerebral activation during human REM sleep. Nature Neuroscience, 3 (8), 831-836. doi:10.1038/77744 https://hdl.handle.net/2268/13241

The most cited

589 citations (Scopus®)

Peigneux, P., Laureys, S., Fuchs, S., Collette, F., Perrin, F., Reggers, J., Phillips, C., Degueldre, C., Del Fiore, G., Aerts, J., Luxen, A., & Maquet, P. (28 October 2004). Are spatial memories strengthened in the human hippocampus during slow wave sleep? Neuron, 44 (3), 535-545. doi:10.1016/j.neuron.2004.10.007 https://hdl.handle.net/2268/21205

Lecomte, F.* , Aerts, J.* , Plenevaux, A., Defraiteur, C., Chappuis-Hugon, F., Rozet, E., CHIAP, P., Luxen, A., Pichon, V., Hubert, P.* , & Hubert, C.*. (20 February 2020). Performance evaluation of a MIP for the MISPE-LC determination of p-[18F]MPPF and a potential metabolite in human plasma. Journal of Pharmaceutical and Biomedical Analysis, 180. doi:10.1016/j.jpba.2019.113015
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Egli, A., Mandal, J., Schumann, D. M., Roth, M., Thomas, B. S., Lorne Tyrrell, D., Blasi, F. B., Kostikas, K. T., Boersma, W. G., Milenkovic, B. A., Lacoma, A., Rentsch, K. M., Rohde, G. G. U., Louis, R., Aerts, J., Welte, T., Torres, A. H., Tamm, M., & Stolz, D. (21 March 2018). IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes. BMC Pulmonary Medicine, 18 (1), 51. doi:10.1186/s12890-018-0616-6
Peer Reviewed verified by ORBi

Mandal, J., Roth, M., Papakonstantinou, E., Sun, Q., Costa, L., Boeck, L., Scherr, A., Rakic, J.-M., Louis, R., Milenkovic, B., Boersma, W., Kostikas, K., Blasi, F., Aerts, J., Rohde, G., Lacoma, A., Torres, A., Welte, T., Tamm, M., & Stolz, D. (2018). Treatment with long acting muscarinic antagonists stimulates serum levels of irisin in patients with COPD. Pulmonary Pharmacology and Therapeutics, 48, 111-116. doi:10.1016/j.pupt.2017.10.011
Peer Reviewed verified by ORBi

Serrano Navacerrada, M. E., Becker, G., Bahri, M. A., Warnier, C., Aerts, J., Mievis, F., Giacomelli, F., Lemaire, C., Salmon, E., Luxen, A., & Plenevaux, A. (December 2017). Sv2a protein levels in the kainic acid epilepsy rat model during the acute phase. Epilepsia, 58 (Supplement S5), 1–S225.

Bahri, M. A., Plenevaux, A., Aerts, J., Bastin, C., Becker, G., Mercier, J., Valade, A., Buchanan, T., Mestdagh, N., LEDOUX, D., Seret, A., Luxen, A., & Salmon, E. (November 2017). Measuring brain synaptic vesicle protein 2A with positron emission tomography and [18F]UCB-H. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 4 (4), 481-486. doi:10.1016/j.trci.2017.08.004
Peer Reviewed verified by ORBi

Serrano Navacerrada, M. E., Becker, G., Bahri, M. A., Warnier, C., Aerts, J., Mievis, F., Giacomelli, F., Lemaire, C., Salmon, E., Luxen, A., & Plenevaux, A. (01 February 2017). Evaluating the specificity of [18F] UCB-H for the isoform SV2A, compared with isoforms SV2B and SV2C [Poster presentation]. GIGA Day 2017, Liège, Belgium.

Serrano Navacerrada, M. E., Becker, G., Bahri, M. A., Warnier, C., Aerts, J., Mievis, F., Giacomelli, F., Lemaire, C., Salmon, E., Luxen, A., & Plenevaux, A. (2017). [18F]UCB-H RADIOTRACER AS A TOOL TO UNDERSTAND THE ROLE OF THE SV2A PROTEIN [Poster presentation]. PhD Student Day, Liège, Belgium.

Salmon, E., Bahri, M. A., Manard, M., Plenevaux, A., Becker, G., Seret, A., Mella, C., Aerts, J., Giacomelli, F., Luxen, A., & Bastin, C. (2017). Decreased Synaptic Density in Early Alzheimer’s Disease Assessed with [18F]UCB-H-PET. Alzheimer's and Dementia, 13 (7), 781.
Peer reviewed

Rouzet, F., Aerts, J., Hyafil, F., & Le Guludec, D. (2017). New-generation CZT cameras: the future of infection imaging? European Heart Journal, 38, 444–446. doi:10.1093/eurheartj/ehw376
Peer Reviewed verified by ORBi

Serrano Navacerrada, M. E., Becker, G., Bahri, M. A., Warnier, C., Aerts, J., Mievis, F., Giacomelli, F., Lemaire, C., Salmon, E., Luxen, A., & Plenevaux, A. (2017). IN VIVO STUDY OF THE SV2A PROTEIN IN AN EPILEPTIC RAT MODEL [Poster presentation]. 3rd Belgium Molecular Imaging Congress (BMIC 2017), Brussels, Belgium.

Serrano Navacerrada, M. E., Becker, G., Bahri, M. A., Warnier, C., Aerts, J., Mievis, F., Giacomelli, F., Lemaire, C., Salmon, E., Luxen, A., & Plenevaux, A. (2017). IN VIVO STUDY OF THE SV2A PROTEIN IN THE KAINIC ACID EPILEPSY RAT MODEL [Poster presentation]. 12th European Molecular Imaging Meeting (EMIM 2017), Cologne, Germany.

Serrano Navacerrada, M. E., Aerts, J., Bahri, M. A., Becker, G., Giacomelli, F., Lemaire, C., Luxen, A., Mercier, J., Mestdagh, N., Mievis, F., Plenevaux, A., Salmon, E., & Warnier, C. (18 November 2016). EVALUATING THE SPECIFICITY OF [18F]UCB-H FOR THE ISOFORM SV2A, COMPARED WITH ISOFORMS SV2B AND SV2C [Poster presentation]. MedChem 2016 PET & Imaging : From Chemistry Lab to Clinical Applications, Mont-Saint-Guibert, Belgium.

Warnier, C., Lemaire, C., Becker, G., Zaragoza, G., Giacomelli, F., Aerts, J., Otabashi, M., Bahri, M. A., Mercier, J., Plenevaux, A., & Luxen, A. (06 September 2016). Enabling efficient PET imaging of Synaptic Vesicle glycoprotein 2A (SV2A) with a robust and one-step radiosynthesis of a highly potent 18F-labelled ligand ([18F]UCB-H). Journal of Medicinal Chemistry, 59, 8955-8966. doi:10.1021/acs.jmedchem.6b00905
Peer Reviewed verified by ORBi

Mikail, N., Louedec, L., Aid, R., Al Shoukr, F., Anizan, N., Aerts, J., Michel, J.-B., Chauvierre, C., Le Guludec, D., & Rouzet, F. (June 2016). Detection of myocardial ischemic memory using 99mTc-fucoidan: preclinical validation [Paper presentation]. ASNMMI.

Chollet, L., Saboural, P., Rouzet, F., Maire, M., Aerts, J., Louedec, Al-Shoukr, F., & Rachida, A. A. (2016). Fucoidan: a marine polysaccharide for SPECT diagnosis of thrombosis. In Frontiers. doi:10.3389/conf.FBIOE.2016.01.01999
Peer reviewed

Mikail, N., Louedec, L., Aid, R., Al Shoukr, F., Anizan, N., Aerts, J., Michel, J., Chauvièrre, C., Le Guludec, D., & Rouzet, F. (May 2016). Détection de la mémoire ischémique myocardique par le 99mTc-fucoïdane : validation pré-clinique [Paper presentation]. Journées Francophones de Médecine Nucléaire, Grenoble, France.

Bahri, M. A., Stifkens, M., Bastin, C., Aerts, J., Bretin, F., Warnock, G., Buchanan, T., Mella, C., Mestdagh, N., Otoul, C., Koester, F., Valade, A., Mercier, J., Lemaire, C., Giacomelli, F., Mievis, F., Léonard, M., Seret, A., Luxen, A., ... SALMON, E. (09 May 2015). [18F]UCB-H as a new PET radiotracer for Synaptic vesicle protein 2A: A first clinical trial. Tijdschrift voor Nucleaire Geneeskunde, 37 (3), 1457-1458.
Peer reviewed

Aerts, J., Giacomelli, F., Hubert, P., Ianniello, J., & Marini Djang'Eing'A, R. (09 May 2015). RADIOPHARMACY GMP QC HPLC VALIDATION [Paper presentation]. 17 th symposium the Belgian Society of Nuclear Medicine, Maastricht, Netherlands.

Bahri, M. A., Stifkens, M., Bastin, C., Aerts, J., Bretin, F., Warnock, G., Buchanan, T., Mella, C., Mestdagh, N., Otoul, C., Koester, F., Valade, A., Mercier, J., Lemaire, C., Giacomelli, F., Mievis, F., Léonard, M., Seret, A., Luxen, A., ... SALMON, E. (27 January 2015). [18F]UCB-H as a new PET radiotracer for Synaptic vesicle protein 2A: A first clinical trial [Poster presentation]. 2015 GIGA day, Liège, Belgium.

Bretin, F., Bahri, M. A., BERNARD, C., Warnock, G., Aerts, J., Mestdagh, N., Buchanan, T., Otoul, C., Koestler, F., Mievis, F., Giacomelli, F., Degueldre, C., Hustinx, R., Luxen, A., Seret, A., Plenevaux, A., & Salmon, E. (17 January 2015). Biodistribution and radiation dosimetry for the novel SV2A radiotracer [18F]UCB-H: First-in-human study. Molecular Imaging and Biology, 17, 557-564. doi:10.1007/s11307-014-0820-6
Peer Reviewed verified by ORBi

Aerts, J., Ballinger, J., Behe, M., Decristoforo, C., Elsinga, P., Faivre-Chauvet, A., Mindt, T., Kolenc Peitl, P., Todde, S., & Koziorowski, J. (05 September 2014). Guidance on current good radiopharmacy practice for the small-scale preparation of radiopharmaceuticals using automated modules: a European perspective. Journal of Labelled Compounds and Radiopharmaceuticals, 57. doi:10.1002/jlcr.3227
Peer Reviewed verified by ORBi

Warnock, G., Aerts, J., Bahri, M. A., Bretin, F., Lemaire, C., Giacomelli, F., Mievis, F., Mestdagh, N., Buchanan, T., Valade, A., Mercier, J., Wood, M., Gillard, M., Seret, A., Luxen, A., SALMON, E., & Plenevaux, A. (01 August 2014). Evaluation of [18F]UCB-H as a novel PET tracer for synaptic vesicle protein 2A in the brain. Journal of Nuclear Medicine, 55 (8), 1336-1341. doi:10.2967/jnumed.113.136143
Peer Reviewed verified by ORBi

Bahri, M. A., Bastin, C., Aerts, J., Bretin, F., Warnock, G., Buchanan, T., Mella, C., Mestdagh, N., Otoul, C., Koester, F., Valade, A., Mercier, J., Lemaire, C., Giacomelli, F., Mievis, F., Léonard, M., Seret, A., Luxen, A., Plenevaux, A., & Salmon, E. (06 June 2014). [18F]UCB-H AS A NEW PET RADIOTRACER FOR SYNAPTIC VESICLE PROTEIN 2A [Poster presentation]. European Molecular Imaging Meeting - EMIM 2014, Antwerp, Belgium.

Bahri, M. A., Bastin, C., Aerts, J., Bretin, F., Warnock, G., Buchanan, T., Mella, C., Mestdagh, N., Otoul, C., Koester, F., Valade, A., Mercier, J., Lemaire, C., Mievis, F., Léonard, M., Seret, A., Luxen, A., Plenevaux, A., & Salmon, E. (27 May 2014). [18F]UCB-H AS A BRAIN SV2A RADIOTRACER: A FIRST CLINICAL TRIAL [Poster presentation]. XIII Turku PET Symposium, Turku, Finland.

Léonard, M., Aerts, J., Voccia, S., Lemaire, C., Morelle, J.-L., Phillipart, G., & Luxen, A. (22 October 2013). Fully Automated Production of 68Ga-DOTA-NOC with a Trasis miniAIO® Synthesizer [Poster presentation]. EANM'13 - Annual Congress of the European Association of Nuclear Medicine, Lyon, France.

Warnier, C., Lemaire, C., Goblet, D., Aerts, J., Flagothier, J., Libert, L., & Luxen, A. (16 May 2013). Preliminary evaluation of two recently developed evaporation-free [18F]fluorination methods on aromatic precursors [Poster presentation]. 20th symposium on radiopharmaceutical sciences, Jeju, South Korea.

Bretin, F., Warnock, G., Bahri, M. A., Aerts, J., Mestdagh, N., Buchanan, T., Valade, A., Mievis, F., Giacomelli, F., Lemaire, C., Luxen, A., Salmon, E., Seret, A., & Plenevaux, A. (07 May 2013). Preclinical radiation dosimetry for the novel SV2A radiotracer [18F]UCB-H. EJNMMI Research, 3 (1), 35. doi:10.1186/2191-219X-3-35
Peer Reviewed verified by ORBi

Warnock, G., Aerts, J., Mestdagh, N., Valade, A., Mercier, J., Buchanan, T., Plenevaux, A., & Luxen, A. (2013). Evaluation of a new [18F] labeled tracer targeting synaptic vesicle protein 2C by ex vivo autoradiography and in vivo PET study in rat brain [Poster presentation]. European Molecular Imaging Meeting EMIM 2013.

Aerts, J., Otabashi, M., Giacomelli, F., Warnock, G., Bahri, M. A., Bretin, F., Sauvage, X., Thielen, C., Lemaire, C., Salmon, E., Plenevaux, A., & Luxen, A. (2013). Radiosynthesis and first small animal microPET imaging of [18F]UCB-H, a new fluorine-18 labelled tracer targeting synaptic vesicle protein 2A (SV2A) [Paper presentation]. 26th Annual Congress of the EANM.

Aerts, J., Renard, Léonard, M., & Luxen, A. (2013). Customizing an adaptive case management software in a GMP production lab as a quality management system for clinical trial PET radiopharmaceuticals development and production [Poster presentation]. European Molecular Imaging Meeting EMIM2013.

Warnock, G., Aerts, J., Bahri, M. A., Bretin, F., Buchanan, T., Klitgaard, H., Mestdagh, N., Valade, A., Mercier, J., Seret, A., Luxen, A., SALMON, E., & Plenevaux, A. (September 2012). CHARACTERIZATION OF A NOVEL RADIOTRACER TARGETING SYNAPTIC VESICLE PROTEIN 2A (SV2A) [Poster presentation]. World Molecular Imaging Congress, Dublin, Ireland.

Lemaire, C., Libert, L., Plenevaux, A., Aerts, J., Franci, X., & Luxen, A. (24 March 2012). Fast and reliable method for the preparation of ortho- and para-[18F]fluorobenzyl halide derivatives: Key intermediates for the preparation of no-carrier-added PET aromatic radiopharmaceuticals. Journal of Fluorine Chemistry, 138, 48-55. doi:10.1016/j.jfluchem.2012.03.015
Peer Reviewed verified by ORBi

Warnock, G., Bahri, M. A., Goblet, D., Giacomelli, F., Lemaire, C., Aerts, J., Seret, A., Langlois, X., Luxen, A., & Plenevaux, A. (10 August 2011). Use of a beta microprobe system to measure arterial input function in PET via an arteriovenous shunt in rats. EJNMMI Research, 1, 13. doi:10.1186/2191-219X-1-13
Peer Reviewed verified by ORBi

Bastin, C., Kerrouche, N., LEKEU, F., Adam, S., Guillaume, B., Lemaire, C., Aerts, J., D'Ydewalle, G., Collette, F., & SALMON, E. (2011). Neural correlates of controlled memory processes in questionable Alzheimer’s disease. In J. W. Ashford, A. Rosen, M. Adamson, P. Bayley, O. Sabri, A. Furst, S. E. Black, ... M. Weiner (Eds.), Advances in Alzheimer's Disease. Volume 2: Handbook of imaging the Alzheimer brain. Amsterdam, Netherlands: IOS Press.

collet, C., Lamandé-Langle, S., Balentova, E., Chrétien, F., Thonon, D., Aerts, J., Lemaire, C., Luxen, A., & Chapleur, Y. (2011). Synthesis and hydrolytic stability of novel 3-[18F]fluoroethoxybis(1-methylethyl)silyl]propanaminebased prosthetic groups [Poster presentation]. 19th International Symposium on Radiopharmaceutical Sciences.

Withofs, N., Grayet, B., Tancredi, T., Rorive, A., Mella, C., Giacomelli, F., Mievis, F., Aerts, J., Waltregny, D., Jerusalem, G., & Hustinx, R. (2011). 18F-fluoride PET/CT for assessing bone involvement in prostate and breast cancers. Nuclear Medicine Communications, 32 (3), 168-176. doi:10.1097/MNM.0b013e3283412ef5
Peer Reviewed verified by ORBi

Balentova, E., Collet, C., Lamande-Langle, S., Chretien, F., Thonon, D., Aerts, J., Lemaire, C., Luxen, A., & Chapleur, Y. (2011). Synthesis and hydrolytic stability of novel 3-[18F]fluoroethoxybis(1-methylethyl)silyl]propanamine-based prosthetic groups. Journal of Fluorine Chemistry, 132 (4), 250-257. doi:10.1016/j.jfluchem.2011.01.011
Peer Reviewed verified by ORBi

Thonon, D., Goblet, D., Goukens, E., Kaisin, G., Paris, J., Aerts, J., Lignon, S., Franci, X., Hustinx, R., & Luxen, A. (2011). Fully Automated Preparation and Conjugation of N-Succinimidyl 4-[(18)F]Fluorobenzoate ([ (18)F]SFB) with RGD Peptide Using a GE FASTlab Synthesizer. Molecular Imaging and Biology. doi:10.1007/s11307-011-0470-x
Peer Reviewed verified by ORBi

Bastin, C., Kerrouche N, Lekeu, F., Adam, S., Guillaume B, Lemaire, C., Aerts, J., d'Idewalle G, Collette, F., & Salmon, E. (June 2010). Controlled Memory Processes in Questionable Alzheimer's Disease: A View from Neuroimaging Research. Journal of Alzheimer's Disease, 20 (2), 547-560. doi:10.3233/JAD-2010-1393
Peer Reviewed verified by ORBi

Aerts, J., Voccia, S., Lemaire, C., Giacomelli, F., Goblet, D., Thonon, D., Plenevaux, A., Warnock, G., & Luxen, A. (2010). Fast production of highly concentrated reactive [18F] fluoride for aliphatic and aromatic nucleophilic radiolabelling. Tetrahedron Letters, 51, 64-66. doi:10.1016/j.tetlet.2009.10.085
Peer Reviewed verified by ORBi

Lemaire, C., Aerts, J., Voccia, S., Libert, L., Mercier, F., Goblet, D., Plenevaux, A., & Luxen, A. (2010). Fast Production of Highly Reactive No-Carrier-Added [18F]Fluoride for the Labeling of Radiopharmaceuticals. Angewandte Chemie International Edition, 49, 1-5. doi:10.1002/anie.200906341
Peer Reviewed verified by ORBi

Lemaire, C., Voccia, S., Aerts, J., Luxen, A., Morelle, J.-L., & Phillipart, G. (01 August 2009). Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium suitable for radiolabeling without any evaporation step by the use of strong organic bases.

Aerts, J., Lemaire, C., Plenevaux, A., & Luxen, A. (July 2009). Are Ionic Liquid Useful for Fluorine-18 Labeling? Journal of Labelled Compounds and Radiopharmaceuticals, 52 (S1), 193.
Peer Reviewed verified by ORBi

Libert, L., Lemaire, C., Denoël, T., Plenevaux, A., Aerts, J., & Luxen, A. (July 2009). New Improvements in the Enantioselective Synthesis of 2-[18F]Fluoro-L-Tyrosine and 6-[18F]Fluoro-L-Dopa. Journal of Labelled Compounds and Radiopharmaceuticals, 52 (S1), 196.
Peer Reviewed verified by ORBi

Lemaire, C., Aerts, J., Voccia, S., Plenevaux, A., & Luxen, A. (July 2009). Use of Organic Bases for 18F-Fluoride Anion Exchange Elution avoiding the Classical Azeotropic drying Step Before Labeling. Journal of Labelled Compounds and Radiopharmaceuticals, 52 (S1), 198.
Peer Reviewed verified by ORBi

Aerts, J., Voccia, S., Lemaire, C., Thonon, D., Plenevaux, A., & Luxen, A. (July 2009). Tertiary Alcohols to Avoid Evaporation in Fluorine-18 Labeling. Journal of Labelled Compounds and Radiopharmaceuticals, 52 (S1), 204.
Peer Reviewed verified by ORBi

Aerts, J., Voccia, S., Lemaire, C., Giacomelli, F., Goblet, D., Thonon, D., Plenevaux, A., & Luxen, A. (July 2009). Modified Non-Ionic Solid Supports: a Way to High Activity Fluorine-18 Radiochemistry in Microfluidic Devices. Journal of Labelled Compounds and Radiopharmaceuticals, 52 (S1), 12.
Peer Reviewed verified by ORBi

Bastin, C., Leclercq, Y., Collette, F., Lemaire, C., Aerts, J., Perani, D., Holthoff, V., Beuthien-Baumann, B., Sorbi, S., Herholz, K., & Salmon, E. (2009). Multivariate analysis of cognitive profiles in Alzheimer's disease. In Proceedings of the 8th bi-annual Meeting of the Belgian Society for Neuroscience (pp. 52).
Peer reviewed

Bastin, C., Adam, S., LEKEU, F., Guillaume, B., Lemaire, C., Aerts, J., Collette, F., & Salmon, E. (2009). Combiner les mesures métaboliques cérébrales et neuropsychologiques permet une meilleure prédiction de la conversion vers une maladie d’Alzheimer chez les patients MCI. Revue Neurologique, 165, 80.
Peer Reviewed verified by ORBi

Aerts, J. (2008). Composés radiopharmaceutiques marqués au fluor-18 utilisés en routine clinique: nouvelles méthodes de production et validation animale [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315338

Aerts, J., Plenevaux, A., Lemaire, C., Giacomelli, F., Warnock, G., Phillips, C., & Luxen, A. (07 November 2008). Metabolism of no-carrier-added 2-[18F]fluoro-L-tyrosine in rats. BMC Medical Physics, 8, 4. doi:10.1186/1756-6649-8-4
Peer Reviewed verified by ORBi

Voccia, S., Aerts, J., Lemaire, C., Luxen, A., Morelle, J.-L., & Philippart, G. (30 October 2008). Method for the preparation of reactive [18F]fluoride.

Aerts, J., Lemaire, C., Lignon, S., Luxen, A., Morelle, J.-L., Philippart, G., & Voccia, S. (28 August 2008). Methof for the elution of 18F fluoride trapped on an anion-exchange phase in a form suitable for efficient radiolabelling without any evaporation step.

Lacan, G., Plenevaux, A., Rubins, D. J., Way, B. M., Defraiteur, C., Lemaire, C., Aerts, J., Luxen, A., Cherry, S. R., & Melega, W. P. (2008). Cyclosporine, a P-glycoprotein modulator, increases [18F]MPPF uptake in rat brain and peripheral tissues: microPET and ex vivo studies. European Journal of Nuclear Medicine and Molecular Imaging, 35 (12), 2256-66. doi:10.1007/s00259-008-0832-z
Peer Reviewed verified by ORBi

Bastin, C., Kerrouche, N., LEKEU, F., Adam, S., Guillaume, B., Lemaire, C., Aerts, J., d'Ydewalle, G., Collette, F., & Salmon, E. (2008). Metabolic correlates of controlled memory processes in very early Alzheimer’s disease and stable questionable Alzheimer’s disease [Paper presentation]. Recollection workshop, Tours, France.

Bastin, C., Kerrouche, N., Lekeu, F., Adam, S., Guillaume, B., Lemaire, C., Aerts, J., & Salmon, E. (2008). Les corrélats métaboliques des processus contrôlés en mémoire dans la maladie d'Alzheimer très débutante. In A.-M. Ergis, N. Fiori, L. Chaby, C. Belin, L. Fabre, ... D. Gandini (Eds.), Xème colloque international sur le vieillissement cognitif (pp. 93). Paris, France: Publibook.

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (September 2007). PPERFORMANCE EVALUATION OF TWO MIPS FOR THE SPE-LC-UV DETERMINATION OF p-[18F]MPPF IN PLASMA [Poster presentation]. RDPA 2007, 12th Internatioinal Meeting on Recent Developments in Pharmaceutical Analysis, Island of Elba, Italy.

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Denjean, C., Chapuis-Hugon, F., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (June 2007). DEVELOPMENT AND VALIDATION OF A METHOD FOR THE LC DETERMINATION p-[18F]MPPF IN PLASMA USING A MISPE [Poster presentation]. HPLC 2007 - 31st International Symposium on High Performance Liquid Phase Separations and Related Techniques, Ghent, Belgium.

Rutten, I., Cabay, J.-E., Withofs, N., Lemaire, C., Aerts, J., Baart, V., & Hustinx, R. (May 2007). PET/CT of skull base meningiomas using 2-F-18-fluoro-L-tyrosine: Initial report. Journal of Nuclear Medicine, 48 (5), 720-725. doi:10.2967/jnumed.106.038216
Peer Reviewed verified by ORBi

Lecomte, F., Aerts, J., Houbart, V., Plenevaux, A., Lignon, S., Chiap, P., Crommen, J., Luxen, A., Pichon, V., & Hubert, P. (2007). EVALUATION DE DEUX POLYMERES A EMPREINTES MOLECULAIRES POUR LE DOSAGE DU p-[18F]MPPF DANS LE PLASMA [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages - SEP07, Grenoble, France.

Rutten, I., Cabay, J.-E., Withofs, N., Lemaire, C., Aerts, J., Baart, V., & HUSTINX, R. (2007). PET/CT imaging of skull base meningiomas using 2-18F-fluoro-L-tyrosine : Initial report. Journal of Nuclear Medicine, 48 (SUPPL), 11.
Peer Reviewed verified by ORBi

Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Haber, G., Boulanger, B., Chiap, P., Luxen, A., & Hubert, P. (September 2006). EVALUATION OF MOLECULARLY IMPRINTED POLYMERS BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF p-[18F]MPPF IN PLASMA [Poster presentation]. MIP2006 - Fourth International Workshop on Molecularly Imprinted Polymers, Cardiff, United Kingdom.

Destrebecqz, A., Peigneux, P., Laureys, S., Degueldre, C., Del Fiore, G., Aerts, J., Luxen, A., Van der Linden, M., Cleeremans, A., & Maquet, P. (2005). The neural correlates of implicit and explicit sequence learning : Interacting networks revealed by the process dissociation procedure. Learning and Memory, 12 (5), 480-490. doi:10.1101/lm.95605
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Peigneux, P., Laureys, S., Fuchs, S., Collette, F., Perrin, F., Reggers, J., Phillips, C., Degueldre, C., Del Fiore, G., Aerts, J., Luxen, A., & Maquet, P. (28 October 2004). Are spatial memories strengthened in the human hippocampus during slow wave sleep? Neuron, 44 (3), 535-545. doi:10.1016/j.neuron.2004.10.007
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Lemaire, C., Gillet, S., Guillouet, S., Plenevaux, A., Aerts, J., & Luxen, A. (2004). Highly enantioselective synthesis of no-carrier-added 6-[18F]Fluoro-L-dopa by chiral phase-transfer alkylation. European Journal of Organic Chemistry, (13), 2899-2904. doi:10.1002/ejoc.200400059
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Peigneux, P., Van der Linden, M., Garraux, G., Laureys, S., Degueldre, C., Aerts, J., Del Fiore, G., Moonen, G., Luxen, A., & Salmon, E. (March 2004). Imaging a cognitive model of apraxia: The neural substrate of gesture-specific cognitive processes. Human Brain Mapping, 21 (3), 119-142. doi:10.1002/hbm.10161
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Peigneux, P., Laureys, S., Fuchs, S., Destrebecqz, A., Collette, F., Delbeuck, X., Phillips, C., Aerts, J., Del Fiore, G., Degueldre, C., Luxen, A., Cleeremans, A., & Maquet, P. (September 2003). Learned material content and acquisition level modulate cerebral reactivation during posttraining rapid-eye-movements sleep. NeuroImage, 20 (1), 125-134. doi:10.1016/S1053-8119(03)00278-7
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Hustinx, R., Lemaire, C., Jerusalem, G., Moreau, P., Cataldo, D., Duysinx, B., Aerts, J., Fassotte, M.-F., Foidart, J., & Luxen, A. (April 2003). Whole-body tumor imaging using PET and 2-18F-fluoro-l-tyrosine: Preliminary evaluation and comparison with 18F-FDG. Journal of Nuclear Medicine, 44 (4), 533-539.
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Destrebecqz, A., Peigneux, P., Laureys, S., Degueldre, C., Del Fiore, G., Aerts, J., Luxen, A., Van Der Linden, M., Cleeremans, A., & Maquet, P. (2003). Cerebral correlates of explicit sequence learning. Cognitive Brain Research, 16 (3), 391-398. doi:10.1016/S0926-6410(03)00053-3
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Laureys, S., Antoine, S., Boly, M., Elincx, S., Faymonville, M.-E., Berré, J., Sadzot, B., Ferring, M., De Tiège, X., van Bogaert, P., Hansen, I., Damas, P., Mavroudakis, N., Lambermont, B., Del Fiore, G., Aerts, J., Degueldre, C., Phillips, C., Franck, G., ... Maquet, P. (December 2002). Brain function in the vegetative state. Acta Neurologica Belgica, 102 (4), 177-185.
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Laureys, S., Faymonville, M.-E., Peigneux, P., Damas, P., Lambermont, B., Del Fiore, G., Degueldre, C., Aerts, J., Luxen, A., Franck, G., Lamy, M., Moonen, G., & Maquet, P. (October 2002). Cortical processing of noxious somatosensory stimuli in the persistent vegetative state. NeuroImage, 17 (2), 732-741. doi:10.1016/S1053-8119(02)91236-X
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Mosdzianowski, C., Lemaire, C., Simoens, F., Aerts, J., Morelle, J. L., & Luxen, A. (June 2002). Epimerization study on [18F]FDG produced by an alkaline hydrolysis on solid support under stringent conditions. Applied Radiation and Isotopes, 56 (6), 871-875. doi:10.1016/S0969-8043(01)00145-2
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Plenevaux, A., Lacan, G., Defraiteur, C., Gillet, S., Way, B. M., Rubin, D. J., Lemaire, C., Aerts, J., Melega, W. P., & Luxen, A. (2002). Influence of P-glycoprotein on the tissue distribution in rats of the 5-HT1A antagonist p-[18F]MPPF [Paper presentation]. Society for Neuroscience, 32nd annual meeting, Orlando, United States.

HUSTINX, R., Lemaire, C., JERUSALEM, G., MOREAU, P., Cataldo, D., DUYSINX, B., Aerts, J., & Luxen, A. (2002). 18F-fluoro-L-tyrosine : a potential tracer for whole-body tumor imaging with PET. Journal of Nuclear Medicine, 43, 77.
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Lemaire, C., Damhaut, P., Lauricella, B., Mosdzianowski, C., Morelle, J. L., Monclus, M., Van Naemen, J., Mulleneers, E., Aerts, J., Plenevaux, A., Brihaye, C., & Luxen, A. (2002). Fast F-18 FDG synthesis by alkaline hydrolysis on a low polarity solid phase supports. Journal of Labelled Compounds and Radiopharmaceuticals, 45 (5), 435-447. doi:10.1002/jlcr.572
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Peigneux, P., Laureys, S., Fuchs, S., Delbeuck, X., Degueldre, C., Aerts, J., Delfiore, G., Luxen, A., & Maquet, P. (September 2001). Generation of rapid eye movements during paradoxical sleep in humans. NeuroImage, 14 (3), 701-708. doi:10.1006/nimg.2001.0874
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Laureys, S., Peigneux, P., Phillips, C., Fuchs, S., Degueldre, C., Aerts, J., Del Fiore, G., Petiau, C., Luxen, A., Van der Linden, M., Cleeremans, A., Smith, C., & Maquet, P. (2001). Experience-dependent changes in cerebral functional connectivity during human rapid eye movement sleep. Neuroscience, 105 (3), 521-525. doi:10.1016/S0306-4522(01)00269-X
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Laureys, S., Faymonville, M.-E., Berre, J., Antoine, S., Damas, P., Van Bogaert, P., Lambermont, B., Damas, F., Janssens, N., Degueldre, C., Lemaire, C., Del Fiore, G., Aerts, J., Ebinger, G., Luxen, A., Moonen, G., Lamy, M., Goldrnan, S., & Maquet, P. (2001). Etudes par tomographie à émission de positons chez des patients en coma, en état végétatif ou de conscience minimale, en «locked-in syndrome» et en mort cérébrale. In L'évaluation neurophysiologique des comas, de la mort encéphalique et des états végétatifs (pp. 367-376).

Peigneux, P., Maquet, P., Meulemans, T., Destrebecqz, A., Laureys, S., Degueldre, C., Delfiore, G., Aerts, J., Luxen, A., Franck, G., Van der Linden, M., & Cleeremans, A. (August 2000). Striatum forever, despite sequence learning variability : A random effect analysis of PET data. Human Brain Mapping, 10 (4), 179-194. doi:10.1002/1097-0193(200008)10:4<179::AID-HBM30>3.0.CO;2-H
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Maquet, P., Laureys, S., Peigneux, P., Fuchs, S., Petiau, C., Phillips, C., Aerts, J., Del Fiore, G., Degueldre, C., Meulemans, T., Luxen, A., Franck, G., Van der Linden, M., Smith, C., & Cleeremans, A. (August 2000). Experience-dependent changes in cerebral activation during human REM sleep. Nature Neuroscience, 3 (8), 831-836. doi:10.1038/77744
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Plenevaux, A., Lemaire, C., Aerts, J., Lacan, G., Rubins, D., Melega, W. P., Brihaye, C., Degueldre, C., Fuchs, S., Salmon, E., Maquet, P., Laureys, S., Damhaut, P., Weissmann, D., Le Bars, D., Pujol, J.-F., & Luxen, A. (July 2000). [(18)F]p-MPPF: A radiolabeled antagonist for the study of 5-HT(1A) receptors with PET. Nuclear Medicine and Biology, 27 (5), 467-71. doi:10.1016/S0969-8051(00)00113-X
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Laureys, S., Faymonville, M., Del Fiore, G., Janssens, N., Degueldre, C., Aerts, J., Lamy, M., Luxen, A., Moonen, G., & Maquet, P. (2000). Brain activation during somatosensory and auditory stimulation in acute vegetative state of anoxic origin. In Physiological imaging of the brain with PET (pp. 319-327 (Chapter 47).

Plenevaux, A., Weissmann, D., Aerts, J., Lemaire, C., Brihaye, C., Degueldre, C., Le Bars, D., Comar, D., Pujol, J. F., & Luxen, A. (2000). Tissue distribution, autoradiography, and metabolism of 4-(2'-methoxyphenyl)-1-[2' -[N-2"-pyridinyl)-p-[(18)F]fluorobenzamido]ethyl]piperazine (p-[(18)F]MPPF), a new serotonin 5-HT(1A) antagonist for positron emission tomography: An In vivo study in rats. Journal of Neurochemistry, 75 (2), 803-11. doi:10.1046/j.1471-4159.2000.0750803.x
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LAUREYS, S., FAYMONVILLE, M.-E., JANSSENS, N., DAMAS, P., DEL FIORE, G., LAMBERMONT, B., Degueldre, C., Aerts, J., Franck, G., Luxen, A., Moonen, G., LAMY, M., & MAQUET, P. (2000). Cerebral processing in vegetative state I: Somatosensory stimulation. NeuroImage, 11(5):S698. doi:10.1016/s1053-8119(00)91628-8
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Laureys, S., Faymonville, M., Degueldre, C., Del Fiore, G., Damas, P., Lambermont, B., Janssens, N., Aerts, J., Franck, G., Luxen, A., Moonen, G., Lamy, M., & Maquet, P. (2000). Auditory processing in the vegetative state. Brain: a Journal of Neurology, 123 ( Pt 8), 1589-601. doi:10.1093/brain/123.8.1589
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Peigneux, P., Salmon, E., Van der Linden, M., Garraux, G., Aerts, J., Delfiore, G., Degueldre, C., Luxen, A., Orban, G., & Franck, G. (2000). The role of lateral occipitotemporal junction and area MT/V5 in the visual analysis of upper-limb postures. NeuroImage, 11 (6), 644-655. doi:10.1006/nimg.2000.0578
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LAUREYS, S., FAYMONVILLE, M.-E., DAMAS, P., DEL FIORE, G., LAMBERMONT, B., Degueldre, C., Aerts, J., Franck, G., Luxen, A., LAMY, M., Moonen, G., & MAQUET, P. (2000). Cerebral processing in vegetatieve state II: Auditory stimulation. NeuroImage, 11(5):S772.
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Laureys, S., Faymonville, M., Goldman, S., Degueldre, C., Phillips, C., Lambermont, B., Aerts, J., Lamy, M., Luxen, A., Franck, G., & Maquet, P. (2000). Impaired cerebral connectivity in vegetative state. In Physiological imaging of the brain with PET (pp. 329-334 (Chapter 48).

Laureys, S., Goldman, S., Phillips, C., van Bogaert, P., Aerts, J., Luxen, A., Franck, G., & Maquet, P. (April 1999). Impaired effective cortical connectivity in vegetative state : Preliminary investigation using PET. NeuroImage, 9 (4), 377-382. doi:10.1006/nimg.1998.0414
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Plenevaux, A., Lemaire, C., Salmon, E., Laureys, S., Fuchs, S., Maquet, P., Degueldre, C., Aerts, J., Brihaye, C., Damhaut, P., Biver, F., Goldman, S., Le Bars, D., Ginovart, N., Cinotti, L., Pujol, J.-F., & Luxen, A. (1999). 5-HT1A Receptors visualization with p-[18F]MPPF in healthy volunteers [Paper presentation]. XIIIth International Symposium on Radiopharmaceutical Chemistry, Saint Louis, United States.

Plenevaux, A., Weissmann, D., Lemaire, C., Aerts, J., Comar, D., Le Bars, D., Pujol, J.-F., & Luxen, A. (1999). p-[18F]MPPF, 5-HT1A antagonist: comparison to [3H]8-OH-DPAT with autoradiography [Paper presentation]. Society for Neuroscience, 29th annual meeting, Miami, United States.

Lemaire, C., Guillouet, S., Plenevaux, A., Brihaye, C., Aerts, J., & Luxen, A. (1999). The synthesis of 6-[18F]fluoro-L-dopa by chiral catalytic phase-transfer alkylation. Journal of Labelled Compounds and Radiopharmaceuticals, 42, 113.
Peer Reviewed verified by ORBi

Le Bars, D., Ginovart, N., Hassoun, W., Weissmann, D., Lemaire, C., Plenevaux, A., Aerts, J., Luxen, A., Pujol, J.-F., & Leviel, V. (1999). p-[18F]MPPF, a fluoro analog of WAY-100635 for visualisation of 5-HT1A receptors in cat. Journal of Labelled Compounds and Radiopharmaceuticals, 42, 395.
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Lemaire, C., Plenevaux, A., Aerts, J., Del Fiore, G., Brihaye, C., Le Bars, D., Comar, D., & Luxen, A. (1999). Solid phase extraction : An alternative to the use of rotary evaporators for solvent removal in the rapid formulation of PET radiopharmaceuticals. Journal of Labelled Compounds and Radiopharmaceuticals, 42 (1), 63-75. doi:10.1002/(SICI)1099-1344(199901)42:1<63::AID-JLCR167>3.0.CO;2-R
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Fuchs, S., Plenevaux, A., Degueldre, C., Lemaire, C., Aerts, J., Laureys, S., Salmon, E., Maquet, P., Le Bars, D., Pujol, J.-F., & Luxen, A. (1999). 5-HT1A receptor distribution in the human brain: preliminary PET data with p-[18F]MPPF. Society for Neuroscience / Abstracts, 25, 1462.
Peer reviewed

Damhaut, P., Plenevaux, A., Lemaire, C., Aerts, J., Biver, F., Monclus, M., Luxen, A., & Goldman, S. (1999). In vivo studies of p-[18F]MPPF metabolites in human. Journal of Labelled Compounds and Radiopharmaceuticals, 42, 661.
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Aerts, J., Plenevaux, A., Lemaire, C., Brihaye, C., & Luxen, A. (1998). Metabolism of no-carrier-added 2-[18F]fluoro-L-tyrosine in free mooving rats. Society for Neuroscience / Abstracts, 24, 428.
Peer reviewed

Le Bars, D., Lemaire, C., Ginovart, N., Plenevaux, A., Aerts, J., Brihaye, C., Hassoun, W., Leviel, V., Mekhsian, P., Weissmann, D., Pujol, J. F., Luxen, A., & Comar, D. (1998). High-yield radiosynthesis and preliminary in vivo evaluation of p-[18F]MPPF, a fluoro analog of WAY-100635. Nuclear Medicine and Biology, 25 (4), 343-50. doi:10.1016/S0969-8051(97)00229-1
Peer Reviewed verified by ORBi

Plenevaux, A., Aerts, J., Lemaire, C., Brihaye, C., Le Bars, D., Mekhsian, P., Weissmann, D., Pujol, J.-F., Comar, D., & Luxen, A. (29 May 1997). Métabolisme du p-[18]MPPF (antagoniste 5-HT1A) chez le rat [Poster presentation]. Journées franco-belges de pharmacochimie. Onzièmes journées. De la conception à la réalisation en pharmacochimie, Bruxelles, Belgium.

Aerts, J., Plenevaux, A., Lemaire, C., Brihaye, C., & Luxen, A. (29 May 1997). Métabolisme de la 6-fluoro-L-tyrosine chez le rat [Poster presentation]. Journées franco-belges de pharmacochimie. Onzièmes journées. De la conception à la réalisation en pharmacochimie.

Ginovart, N., Le Bars, D., Lemaire, C., Plenevaux, A., Aerts, J., Pujol, J.-F., Weissmann, D., Mekhsian, P., Luxen, A., Comar, D., & Leviel, V. (25 May 1997). Le p-[18F]MPPF: un nouveau ligand pour l'étude par TEP des récepteurs 5-HT1A [Poster presentation]. 3ème Colloque de la Société des Neurosciences, Bordeaux, France.

Plenevaux, A., Aerts, J., Lemaire, C., Brihaye, C., Le Bars, D., Mekhsian, P., Weissmann, D., Pujol, J.-F., Comar, D., & Luxen, A. (1997). Evaluation of p-[18F]MPPF, 5-HT1A antagonist, a potential radiopharmaceutical for PET: tissue distribution, autoradiography and metabolism in rats. Society for Neuroscience / Abstracts, 23, 129.
Peer reviewed

Aerts, J., Plenevaux, A., Lemaire, C., Brihaye, C., & Luxen, A. (1997). Metabolism of no carrier added 2-[18F]fluoro-L-tyrosine in free moving rats. Journal of Labelled Compounds and Radiopharmaceuticals, 40, 145.
Peer Reviewed verified by ORBi

Le Bars, D., Ginovart, N., Lemaire, C., Plenevaux, A., Aerts, J., Pujol, J.-F., Mekhsian, P., Weissmann, D., Leviel, V., Luxen, A., & Comar, D. (1997). Microwave improved synthesis of p-[18F]MPPF, 5-HT1A antagonist and PET sudies on cat brain. Journal of Labelled Compounds and Radiopharmaceuticals, 40, 238.
Peer Reviewed verified by ORBi

Plenevaux, A., Aerts, J., Lemaire, C., Brihaye, C., Le Bars, D., Mekhsian, P., Weissmann, D., Pujol, J.-F., Comar, D., & Luxen, A. (1997). Tissue distribution, autoradiography and metabolism in rats of p-[18F]MPPF: 5-HT1A antagonist. Journal of Labelled Compounds and Radiopharmaceuticals, 40, 148.
Peer Reviewed verified by ORBi

Lemaire, C., Damhaut, P., Lauricella, B., Morelle, J.-L., Monclus, M., Van Naemen, J., Mulleneers, E., Aerts, J., Plenevaux, A., Brihaye, C., & Luxen, A. (1997). Synthesis of [18F]FDG with alkaline hydrolysis on a low polarity solid phase support. Journal of Labelled Compounds and Radiopharmaceuticals, 40, 256.
Peer Reviewed verified by ORBi

Plenevaux, A., Aerts, J., Lemaire, C., Brihaye, C., Le Bars, D., Mekhsian, P., Weissmann, D., Pujol, J.-F., Comar, D., & Luxen, A. (1997). Evaluation of p-[F-18]MPPF, 5-HT1A antagonist, in rats: tissue distribution, autoradiography and metabolism. Journal of Nuclear Medicine, 38, 56.
Peer Reviewed verified by ORBi

Le Bars, D., Lemaire, C., Plenevaux, A., Aerts, J., Leviel, V., Pujol, J.-F., Luxen, A., & Comar, D. (1997). High yield radiosynthesis of p-[F-18]MPPF, 5-HT1A antagonist, and PET studies in cat brain. Journal of Nuclear Medicine, 38, 56.
Peer Reviewed verified by ORBi

Lemaire, C., Plenevaux, A., Del Fiore, G., Aerts, J., Luxen, A., Le Bars, D., & Comar, D. (1995). Sep Pak as alternative to rotary evaporators for radiopharmaceutical formulations. Journal of Labelled Compounds and Radiopharmaceuticals, 37, 723.
Peer Reviewed verified by ORBi

Plenevaux, A., Lemaire, C., Aerts, J., Del Fiore, G., & Luxen, A. (1995). Fast quality control of short-lived radiopharmaceutical compounds with a photodiode array detector. Journal of Labelled Compounds and Radiopharmaceuticals, 37, 695.
Peer Reviewed verified by ORBi

Schmitz, F., Plenevaux, A., Del Fiore, G., Lemaire, C., Aerts, J., & Luxen, A. (1995). S-, N- and O-[11C]methylations of a Nor precursor adsorbed on Al2O3/KF. Journal of Labelled Compounds and Radiopharmaceuticals, 37, 106.
Peer Reviewed verified by ORBi

Del Fiore, G., Schmitz, F., Plenevaux, A., Lemaire, C., Aerts, J., & Luxen, A. (1995). Fast routine production of L-[11C-methyl]methionine with Al2O3/KF in a disposable unit. Journal of Labelled Compounds and Radiopharmaceuticals, 37, 746.
Peer Reviewed verified by ORBi

Schmitz, F., Del Fiore, G., Plenevaux, A., Lemaire, C., Aerts, J., & Luxen, A. (1995). [1-11C]Bromoethane: an alternative to the use of [1-11C]iodoethane. Journal of Labelled Compounds and Radiopharmaceuticals, 37, 111.
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