Random distribution of iron among the two binding sites of transferrin in patients with various hematologic disorders.

Beguin, Yves; Huebers, H.; Finch, C. A.

doi:10.1016/0009-8981(88)90017-4

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Random distribution of iron among the two binding sites of transferrin in patients with various hematologic disorders.

Beguin, Yves; Huebers, H.; Finch, C. A.

1988 • In Clinica Chimica Acta, 173 (3), p. 299-304

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https://hdl.handle.net/2268/6664

DOI
10.1016/0009-8981(88)90017-4

PubMed
3383429

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Keywords :

Hematologic Diseases/blood; Humans; Iron/blood; Isoelectric Focusing; Receptors, Transferrin/analysis

Abstract :

[en] The distribution of iron among the two binding sites of transferrin was studied by isoelectric focusing in 41 patients with a variety of disorders of iron metabolism and erythropoiesis. The proportion of diferric and the two monoferric transferrins were very close to the values predicted from the transferring saturation. It is concluded that iron distribution on transferrin is random or close to random within the experimental error in patients with a variety of clinical disorders.

Disciplines :

Hematology

Author, co-author :

Beguin, Yves ; Centre Hospitalier Universitaire de Liège - CHU > Hématologie clinique

Huebers, H.

Finch, C. A.

Language :

English

Title :

Random distribution of iron among the two binding sites of transferrin in patients with various hematologic disorders.

Publication date :

1988

Journal title :

Clinica Chimica Acta

ISSN :

0009-8981

eISSN :

1873-3492

Publisher :

Elsevier Science, Amsterdam, Netherlands

Volume :

173

Issue :

Pages :

299-304

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 19 February 2009

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Bibliography

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