[en] A model for reticulo-endothelial iron metabolism is proposed which characterises diseases of the reutilisation of iron in man. In idiopathic hemochromatosis the RE cell is defective in withholding iron freed from senescent red cells and unable to control the plasma iron level. Transferrin receptor can be measured in plasma, where its concentration is proportionnal to the number of cellular receptors. Plasma levels of transferrin receptor serve as a convenient monitor of total erythropoiesis.
Disciplines :
Hematology
Author, co-author :
Fillet, Georges ; Centre Hospitalier Universitaire de Liège - CHU > Hématologie clinique
Beguin, Yves ; Centre Hospitalier Universitaire de Liège - CHU > Hématologie clinique
Language :
French
Title :
Reutilisation du fer dans l'organisme et regulation du fer de reserve. Interet du dosage du recepteur de la transferrine dans le plasma.
Alternative titles :
[en] Reutilization of iron in the body and regulation of iron reserves. The value of plasma transferrin receptor levels
Publication date :
1989
Journal title :
Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique
ISSN :
0377-8231
Publisher :
Académie Royale de Médecine de Belgique, Bruxelles, Belgium
