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Patent (Patents)
Modified human growth hormone
Martial, Joseph; Lecomte, Corine
1990
 

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Keywords :
Human; Growth; Hormone
Abstract :
[en] Protein derived from human growth hormone (hGH), which no longer has the first two amino acids of the natural hypophysial hormone at the terminal end of the amino acid, retaining its main biological activity of bone and somatic growth stimulation, but no longer having the transitory and diabetogenic insulin effects generally observed when administering hGH. Said modified growth hormone protein can be used for therapeutic purposes, in particuliar for treating clinical cases where the effects of the growth hormone sugars on the metabolism are to be avoided: patients suffering from cachexia, new-born babies and the elederly.
Disciplines :
Biochemistry, biophysics & molecular biology
Inventor :
Martial, Joseph ;  Université de Liège - ULiège > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire
Lecomte, Corine
Language :
English
Title (54) :
Modified human growth hormone
Publication date (43-45) :
17 June 1990
Filing date (22) :
07 November 1989
Patent/publication number (10-11) :
WO 90/05185
Patent status (13) :
B
Priority number (30) :
88/14514
International classification (IPC) (51) :
C12P21/02; A61K38/27; A61P3/04; A61P43/00; C07K14/00; C07K14/575; C07K14/61; C12N1/21; C12N15/09; C12N15/18; A61K38/00; C12R1/19; C12P21/02; A61K38/27; A61P3/00; A61P43/00; C07K14/00; C07K14/435; C12N1/21; C12N15/09; C12N15/16; A61K38/00; (IPC1-7): A61K37/36; C07K13/00; C12N1/21; C12N15/18
European classification (ECLA) (52) :
C07K14/61
Applicant (71) :
ULg - Université de Liège
Publication organism (19) :
Intellectual Property Organisation
Available on ORBi :
since 21 June 2010

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