[en] Protein derived from human growth hormone (hGH), which no longer has the first two amino acids of the natural hypophysial hormone at the terminal end of the amino acid, retaining its main biological activity of bone and somatic growth stimulation, but no longer having the transitory and diabetogenic insulin effects generally observed when administering hGH. Said modified growth hormone protein can be used for therapeutic purposes, in particuliar for treating clinical cases where the effects of the growth hormone sugars on the metabolism are to be avoided: patients suffering from cachexia, new-born babies and the elederly.
Disciplines :
Biochemistry, biophysics & molecular biology
Inventor :
Martial, Joseph ; Université de Liège - ULiège > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire
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