[en] The paper describes clinical signs and diagnosis in 81 cases of intranasal tumors n the dog, examined at the Small Animal Clinic of the Faculty of Veterinary Medicine of the University of Liege (1990-1995).
Recent diagnostic techniques and therapeutic options are discussed.
The most frequently encountered signs included a decreased or absence of unilateral air passage, observed in 78 cases (96%), and hemorrhagic discharge, observed in 65 cases (80%).
Histopathology identified 2 benign and 79 malignant tumors, 57 epithelial and 22 mesenchymatous, including 2 lymphomas. In 74 cases, rhinoscopy identified an intranasal neoplastic mass; in the 7 remaining cases, tissular material of undetermined nature was observed, and histology of biospsied material confirmed the neoplastic nature.
The time interval between the diagnosis and the death of the animal (spontaneous or by euthanasia) was longer in dogs with an intranasal sarcoma (mean time interval of 7 months) than in dogs with an intranasal carcinoma (mean time interval of 3 months).
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Clercx, Cécile ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Pathologie médicale des petits animaux
Peeters, Dominique ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Médecine interne des animaux de compagnie
Gilbert, S.
Snaps, Frédéric ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Imagerie médicale
Mc Entee, Kathleen ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Pathologie médicale des petits animaux
Henroteaux, Marc ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés
Coignoul, Freddy ; Université de Liège > Département de morphologie et pathologie (DMP) > Département de morphologie et pathologie (DMP)
Language :
English
Title :
Signes cliniques et diagnostic des tumeurs de la cavité nasale chez le chien: une analyse de 81 cas.
CLERCX C., WALLON J., GILBERT S., SNAPS F., COIGNOUL F. Imprint and brush cytology in the diagnosis od canine intranasal tumours. J. Sm. Anim. Pract., 1996, 37, 423-427.
CODNER E.C., LURUS A.G., MILLER J.B., GAVIN P.R., GALLINA A., and BARNEE D.D.Comparison of computed tomography with radiography as a noninvasive diagnostic technique for chronic nasal disease in dogs. J. Am. Vet. Med. Assoc., 1993, 202, 1106-1110.
CONFER A.W., DEPAOLI A. Primary neoplasms of the nasal cavity, paranasal sinuses and nasopharynx in the dog. A report of 16 cases from the files of the AFIP. Vet. Pathol. 1978, 15, 18-30.
DELISLE F. Tumeurs des cavités nasales et sinusales chez le chien, Le point vétérinaire, numéro spécial « Pathologie respiratoire des carnivores », 1995, 27, 579-584.
DELISLE F. , BEGON D. Imagerie des cavités nasosinusales chez le chien. Rec. Med. Vet., 1995, 171, 359-366.
EVANS S.M., GOLDSCHMIDT M., MCKEE L.J., HARVEY C.E. Prognostic factors and survival after radiotherapy for intranasal neoplasms in dogs : 70 cases (1974-1985). Reports of retrospective Studies. J. Am. Vet. Med. Assoc., 1989, 194, 1460-1463.
FORBES LENT SE, HAWKINS EC. Evaluation of rhinoscopy and rhinoscopy-assisted mucosal biopsy in diagnosis of nasal disease in dogs: 119 cases (1985-1989). J. Am. Vet. Med. Assoc. 1992, 201, 1424-1429.
GIBBS C., LANE J.G., DENNY H.R. Radiological features of intranasal lesions in the dog : a review of 100 cases. J. Small Anim. Pract. 1979, 20, 515-535.
HAHN K.A., KNAPP D.W., RICHARDSON R.C., and MATLOCK C.L. Clinical response of nasal adenocarcinoma to cisplatin chemotherapy in 11 dogs. J. Am. Vet. Med. Assoc., 1992, 200, 355-357.
HAYES H.M., WILSON C.P., FRAUMENI J.F. Carcinoma of the nasal cavity and paranasal sinuses in dogs : descriptive epidemiology. Cornell Vet. 1982, 72, 168-179.
KOBLIK P.D. and BERRY C.R. Dorsal plane computed tomographic imaging of the ethmoid region to evaluate chronic nasal disease in the dog. Vet. Radiol., 1990, 31, 92-97.
LAING E., BINNINGTON A G. Surgical therapy of canine nasal tumors: a retrospective study (1982-1986). Can. Vet. J., 29, 809-813.
LEGENDRE A.M., SPAULDING K., KRAHWINKEL D.J. Canine nasal and paranasal sinus tumors. J. Am. Anim. Hosp. Assoc., 1983, 19, 115-123.
MADEWELL B.R., PRIESTER W.A., GILLETTE E.L., SNYDER S.P. Neoplasms of the nasal passages and paranasal sinuses in domesticated Animals as reported by 13 veterinary colleges. Am. J. Vet. Res. 1976, vol. 37, 851-856.
McENTEE M.C., PAGE R.L., HEIDNER G.L., CLINE J.M. and THRALL D.E. A retrospective study of 27 dogs with intranasal neoplasms treated with cobalt radiation. Vet. Radiol. 1991, 32, 135-139.
Mac EWEN E.G., WITHROW S.J., PATNAIK A.K. Nasal tumors in the dog: retrospective evaluation of diagnosis, prognosis, and treatment. J. Am. Vet. Med. Assoc., 1977, 170, 45-48.
MOORE, M.P., GAVIN P.R., KRAFT S.L., DE HAAN C.E., LEATHERS C.W., and DORN R.V. MR, CT and clinical features from four dogs with nasal tumors involving the rostral cerebrum. Vet. Radiol. 1991, 32, 19-25.
MORGAN J.P., SUTER P.F., O'BRIEN T.R., PARK R.D. Tumors in the nasal cavity of the dog : a radiographic study. J. Am. Vet. Radiol. Soc. 1972, 73, 18-26.
MORRIS JS, DUNN KJ, DOBSON JM, WHITE RAS. Effects of radiotherapy alone and surgery and radiotherapy on survival of dogs with nasal tumours. J. Small Anim. Pract., 1994, 35, 567-573.
MORRIS JS, DUNN KJ, DOBSON JM, WHITE RAS. Radiological assessment of severity of canine nasal tumours and relationship with survival. J. Small Anim. Pract. 1996, 37, 1-6.
MOULTON J.E. Tumors of the respiratory system, Tumors in domestic animals, third edition, edited by J.E. Moulton, 1990, 308-313.
NORRIS A.M. Intranasal Neoplasms in the dog. J. Am. Anim. Hosp. Assoc., 1979, 15, 231-236.
PARK RD, BECK ED, LE COUTEUR RA, Comparison of computed tomography and radiography for detecting changes induced by malignant basal neoplasia in dogs. J. Am. Vet. Med. Assoc. 1992, 201, p. 1720 à 1724.
PARODI A.L. Tumeurs des cavités nasales et des sinus chez lc chien : caractères lésionnels et données épidémiologiques. Le point vétérinaire, 1987, 19, 5-10.
PATNAIK A.K. Canine Sinosal Neoplasms : Clinicopathological Study of 285 Cases. J. Am. Anim. Hosp. Assoc., 1989, 25, 103-114.
ROGER K.S., WALKER M.A., HELMAN R.G. Squamous cell carcinoma of the canine nasal cavity and frontal sinus: eight cases. J. Am. Anim. Hosp. Assoc. 1996, 32, 103-110.
ROMUSSI S. , MORTELLARO C.M., FONDA D., CANIATTI M., and P. TARONI. Surgery plus photodynamic therapy in canine nasal tumor management. Proceedings of BSAVA congress, Birmingham April 1993, 221.
SMITH M.O., TURREL J.M., BAILEY C.S. and CAIN G.R. Neurologic abnormalities as the predominant signs of neoplasia of the nasal cavity in dogs and cats: seven cases (1973-1986). J. Am. Vet. Med. Assoc., 1989, 195, 242-245.
SULLIVAN M., LEE R. and SKAE C.A. The radiological features of sixty cases of intra-nasal neoplasia in the dog. J. Small Anim. Pract. 1987, 28, 575-586.
THEISEN S.K., LEWIS D.D., HOSGOOD G. Intranasal tumors in dogs: diagnosis and treatment. The Compedium, 1966, 18, 131-139.
THÉON A.P., MADEWALL B.R., HARB M.K. and DUNGWORTH D.L. Megavoltage irradiation of neoplasms of the nasal and paranasal cavities in 77 dogs. J. Am. Vet. Med. Assoc., 1995, 202, 1469-1475.
THRALL D.E., ROBERTSON I.D., MCLEOD D.A. A comparison of radiographic and computed tomographic findings in 31 dogs with malignant nasal tumors. Vet. Radiol. 1989, 30, 59-66.
THRALL D.E., HARVEY C.E. Radiotherapy of malignant nasal tumors in 21 dogs. J. Am. Vet. Med. Assoc., 1983, 183, 633-666.
THOMPSON J.P., ACKERMAN N., BELLAH J.R., BEALE B.S., and ELLISON G.W. 192 Iridium brachytherapy, using an intracavitary afterload device, for treatment of intranasal neoplasms in dogs. Am. J. Vet. Res., 1992, 53, 617-622.
VENKER-VAN HAAGEN A.J., VAN OOSTERHOUT I.C.A.M., MEIJ B.P. and CLERCX C. L'examen rhinoscopique en clinique des petits animaux: analyse des résultats de 233 rhinoscopies. Pratique Médical et chirurgicale de l'Animal de Compagnie. 1990, 1, 79-86.
WITHROW S.J. Cryosurgical therapy for nasal tumors in the dog. J. Am. Anim. Hosp. Assoc., 1982, 18, 585-589.