Reference : Ventral porencephaly: a cerebral defect associated with multiple congenital anomalies.
Scientific journals : Article
Social & behavioral sciences, psychology : Neurosciences & behavior
Human health sciences : Neurology
Ventral porencephaly: a cerebral defect associated with multiple congenital anomalies.
Stewart, R. M. [> > > >]
Williams, R. S. [> > > >]
Lukl, P. [> > > >]
Schoenen, Jean mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Neuro-anatomie >]
Acta Neuropathologica
Springer Verlag
Yes (verified by ORBi)
New York
[en] Abnormalities, Multiple/pathology ; Autopsy ; Brain/abnormalities ; Cerebral Arteries/abnormalities ; Circle of Willis/abnormalities ; Female ; Frontal Lobe/abnormalities ; Humans ; Infant, Newborn
[en] An infant with multiple congenital anomalies was found at autopsy to have a porencencephalic defect on the ventral surface of the left frontal lobe. The intracranial defect was seen in association with an anomalous configuration of the circle of Willis. The zone of tissue destruction corresponded to the vascular territory of the anterior choroidal and lenticulo-striate branches of the proximal middle cerebral arteries, which were absent on the left. The developmental anomaly of the circle of Willis may have predisposed to tissue destruction by compromising cerebral perfusion at midgestation, a stage of rapid brain growth.

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