[en] In this work, we demonstrated that neonatal cortical progenitors characterized by an expression of a polysialilated form on NCAM (Neural Cell Adhesion Molecule) are able to differentiate into astrocytes or oligodendrocytes. Moreover, those precursors are able of a phenotypic plasticity as they differnetiate into Schwann Cells when grafted into adult demyelinated lesions.
Rogister, Bernard ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine
Language :
French
Title :
Contribution à l'étude de la gliogenèse - Perspectives physiopathologiques et thérapeutiques
Alternative titles :
[en] Study of Gliogenesis - Physiological and therapeutical perspectives