Reference : Correlation entre l'echelle de Liege et un marqueur biochimique de la lesion cerebrale.
Scientific journals : Article
Human health sciences : Laboratory medicine & medical technology
Correlation entre l'echelle de Liege et un marqueur biochimique de la lesion cerebrale.
[en] Correlation between the Liege scale and a biomechanical marker of the cerebral lesion
Born, J. D. [> > > >]
Hans, Pol [Centre Hospitalier Universitaire de Liège - CHU > > Anesthésie et réanimation >]
Chapelle, Jean-Paul mailto [Université de Liège - ULiège > Département de pharmacie > Chimie médicale >]
Bonnal, J. [> > > >]
Yes (verified by ORBi)
[en] Adolescent ; Adult ; Brain Injuries/cerebrospinal fluid/diagnosis/enzymology ; Cerebral Ventricles ; Child ; Child, Preschool ; Creatine Kinase/cerebrospinal fluid ; Female ; Humans ; Male ; Middle Aged ; Reflex
[en] Brain type creatine kinase isoenzyme (CK.-1) was measured in the ventricular cerebrospinal fluid in a series of 42 patients within 7 +/- 3,4 hours following severe head injury (GCS less than or equal to 7, LCS less than or equal to 12). The presence of the CK.-1 isoenzyme correlated with the degree of head injury as indexed by the Glasgow coma scale and the Liege coma scale. There was a significant logarithmic correlation between CK.-1 activity in the C.S.F. and the coma scores. However, the correlation with the Liege coma scale score (r = -0,84) is significantly better (Z = 1,97; p less than 0,05) than with the Glasgow coma scale score (r = -0,65). Thus, the Liege coma scale is a better index of neurological trauma.

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