Reference : Relative prognostic value of clinical, biochemical, echocardiographic and haemodynami...
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
Human health sciences : Laboratory medicine & medical technology
Relative prognostic value of clinical, biochemical, echocardiographic and haemodynamic variables in predicting in-hospital and one-year cardiac mortality after acute myocardial infarction.
Pierard, Luc mailto [Centre Hospitalier Universitaire de Liège - CHU > > Cardiologie >]
Albert, Adelin mailto [Université de Liège - ULiège > Département des sciences de la santé publique > Informatique médicale et biostatistique - Département de mathématique >]
Chapelle, Jean-Paul mailto [Université de Liège - ULiège > Département de pharmacie > Chimie médicale >]
Carlier, J. [> >]
Kulbertus, Henri mailto [Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine) >]
European Heart Journal
Oxford University Press
Yes (verified by ORBi)
United Kingdom
[en] Acute Disease ; Adult ; Aged ; Echocardiography ; Electrocardiography ; Female ; Follow-Up Studies ; Heart Ventricles/physiopathology ; Hemodynamics ; Hospitalization ; Humans ; Male ; Middle Aged ; Myocardial Infarction/enzymology/mortality/physiopathology ; Prognosis
[en] This study examined the relative value of clinical, biochemical, echocardiographic and haemodynamic variables, obtained early after acute myocardial infarction in predicting in-hospital and one-year cardiac mortality in 66 consecutive patients. Clinical examination and cross-section echocardiography were obtained in all 66 patients. An echocardiographic score index was calculated by grading wall motion from 0 to 5 in each of 16 left ventricular segments. Right-sided cardiac catheterization was performed soon after admission in 51 patients. Cardiac enzymes were measured every fourth hour in all patients and peak levels were identified in 55. During the follow-up of one year, 14 patients died of cardiac causes, seven of them during hospital stay; three patients died of a non-cardiac cause and were excluded from analysis. The echocardiographic score index was the best predictor of cardiac death and survival (chi 2 = 35), followed by Killip class on admission (chi 2 = 22), stroke volume index (chi 2 = 17) and a biochemical risk index (chi 2 = 11). Stepwise logistic discriminant analysis performed in the patients in whom all variables were obtained resulted in three independent prognostic variables: the echocardiographic score index, systemic vascular resistance at the time of catheterization and the development of infarct expansion. High- and low-risk patients are well identified by echocardiography in the acute phase of myocardial infarction.

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