[en] Plasma steroid concentrations measured in the post-menopausal women with breast cancer showed a close correlation between the various androgens. The post-menopausal women exhibited a correlation between estrogen receptors (ER) and "arterial" 17 alpha-hydroxyprogesterone levels in the breast. ER levels expressed as a function of plasma (arterial) steroid (P/17 P) molar concentration ratio were distributed within a hyperbola, suggesting the existence of a control mechanism for breast cell ER levels.
Disciplines :
Biochemistry, biophysics & molecular biology General & internal medicine
Author, co-author :
Duvivier, Joseph
Colin, Claude
Hustin, Jean
Albert, Adelin ; Université de Liège - ULiège > Département des sciences de la santé publique > Informatique médicale et biostatistique
Lavigne, Jean
Dive, Georges ; Université de Liège - ULiège > Centre d'ingénierie des protéines
Monfort, Franz
Language :
English
Title :
Comparison of levels of cytosol estrogen receptors with "arterial" and "venous" concentrations of gonadic steroids in mammary tumors.
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