No full text
Article (Scientific journals)
Ontogeny of GABA-ergic and dopaminergic mediation of gnawing behavior in the mouse
Tirelli, Ezio
1987In Psychopharmacology, 92 (1), p. 89-95
Peer Reviewed verified by ORBi
 

Files


Full Text
No document available.

Send to



Details



Abstract :
[en] Examined the ontogenetic course of dopaminergically mediated gnawing and the potentiation of this behavior by muscimol (a gamma-aminobutyric acid receptor agonist) in developing and young adult mice using a time-sampling or a corrugated paper procedure. In Exp I, the older group (14-53 days), displayed a dose-dependent gnawing behavior after intraperitoneal injections of methylphenidate ([MTPD], 20, 30, 50 mg/kg). In 5-, 8-, 11-, and 14-day-old pups, MTPD (10, 20, 50 mg/kg) evoked stereotyped gnawing. Muscimol pretreatment (0.025-2.3 mg/kg) induced a clear-cut potentiation of gnawing elicited by MTPD (10 or 20 mg/kg) as early as 8 days of age. It is argued that the effectiveness of MTPD in inducing gnawing-licking among 5-day-old pups confirms the early maturation of central dopamine receptors reported in the literature. ((c) 1997 APA/PsycINFO, all rights reserved)
Research center :
Centre de Neurosciences Cognitives et Comportementales - ULiège
Disciplines :
Neurosciences & behavior
Author, co-author :
Tirelli, Ezio ;  Université de Liège - ULiège > Département des sciences cognitives > Neuroscience comportementale et psychopharmacologie expér.
Language :
English
Title :
Ontogeny of GABA-ergic and dopaminergic mediation of gnawing behavior in the mouse
Publication date :
1987
Journal title :
Psychopharmacology
ISSN :
0033-3158
eISSN :
1432-2072
Publisher :
Springer Verlag, Berlin, Germany
Volume :
92
Issue :
1
Pages :
89-95
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 26 November 2009

Statistics


Number of views
50 (1 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
11
Scopus citations®
without self-citations
7
OpenCitations
 
10

Bibliography


Similar publications



Contact ORBi